Volume 57, Issue 1

Benjaporn Buranrat, Laddawan Senggunprai, Auemduan Prawan, Veerapol Kukongviriyapan

pp. 161–166 · DOI: 10.5530/001954641324 · 2023

Background/Aim: Piperine (Pip) is an alkaloid that found from natural products and it has been reported to exert anticancer activities. Nevertheless, its anticancer effect has not yet been illustrated in cholangiocarcino…

Li Tan, Huanping Ding, Haimeng Xi

pp. 167–172 · DOI: 10.5530/001954642011 · 2023

Background: The prevalence of oral cancer is high and it is the sixth most occurring cancer in the world. Some of the drugs used to treat oral cancer cause adverse effects and are resistant to treatment. Objectives: This…

Heli H Amin, Nileshkumar Joitaram Patel, Nikita Patel, Dolar Govindbhai Patel

pp. 173–181 · DOI: 10.5530/001954640215 · 2023

Background: Myocardial infarction is a 2nd most important origin of universal death and after coronary revascularization, cardiovascular events occurs further a lot in subjects through DM: 3.5- as well as 2-fold fatality…

Obaid Afzal, Gopal Prasad Agrawal, Ghadah Rashed Ghazi Alotaibi, Raid Saleh Ali Shatat, Habibullah Khalilullah, Zabih Ullah, Mohammad Rashid, Ahmed F Elkirdasy, Benson Mathai K

pp. 182–193 · DOI: 10.5530/001954641726 · 2023

Background: Epilepsy is a deep rooted, partially curable brain illness that affects all individuals irrespective of ages and genders. Despite the discovery of various innovative antiepileptic drugs (AEDs), selectivity an…

Trupti S Chitre, Sheetal Parse, Kalyani Asgaonkar, Vijay Khedekar, Shivani Jadhav, Kunal Pradhan

pp. 194–201 · DOI: 10.5530/001954641712 · 2023

Aim and Background: Bacterial Infection is a leading cause of death worldwide. Triazoles and thiazolinones (fused) have been reported to possess many biological activities including antibacterial activity. To study 2D an…

Pushkar Kumar Ray, Salahuddin, Avijit Mazumder, Rajnish Kumar, Mohamed Jawed Ahsan, Mohammad Shahar Yar

pp. 202–209 · DOI: 10.5530/001954641727 · 2023

Aim/Background: This research work aims to design and synthesize novel compounds containing pyrazoline moiety in their structure with enhanced anticonvulsant activity in comparison with the standard (Phenytoin) drug. In …

Akhalesh Kumar, Rakhi Mishra, Rupa Mazumder, Avijit Mazumder

pp. 210–217 · DOI: 10.5530/001954641768 · 2023

Aim/Background: Across the world disease of cancer is one of the factors of death and to identify the emerging role of thiosemicarbazide analogs for the cancer disease it was decided to design, and synthesize novel thios…

Amr Salah Abouzied, Mohammed Khaled Bin Break, Bader Huwaimel, Weiam Hussein, Ahmed Alafnan, Kareem Mahmoud Younes

pp. 218–227 · DOI: 10.5530/001954642131 · 2023

Aim/ Background: Pancreatic lipase (PL) inhibition has been suggested to be an effective method for obesity management. In this study, 10 novel thiazole-benzimidazole conjugates were designed. Materials and Methods: Conj…

Khushbu Patel, Ujash Shah, Hirak Joshi, C.N Patel

pp. 228–233 · DOI: 10.5530/001954640245 · 2023

Aim: A simple and economic method was developed as a derivative spectrophotometric study for estimation of evogliptin tartrate in the tablet dosage form. The developed derivative method was validated as per the ICH guide…

Naveen Kumar KL, Ramgopal Dhanwad, Niranjan MS, KC Chaluvaraju

pp. 234–241 · DOI: 10.5530/001954640307 · 2023

In the present study an economic, a precise UV-spectrosphotometric method for estimating Aspirin and Pravastatin sodium in bulk and physical mixture is carried out as there is less paucity of literature on simultaneous e…

Keerthisikha Palur, Sreenivasa Charan Archakam, Bharathi Koganti

pp. 242–249 · DOI: 10.5530/001954641128 · 2023

Aim: The present study aimed to develop and validate chemometric assisted UV spectrophotometric methods for the simultaneous determination of ambroxol hydrochloride (ABH), terbutaline sulphate (TES) and guaiphenesin (GPN…

Sanyam Sharma, Subh Naman, Kamya Goyal, Ashish Baldi

pp. 250–263 · DOI: 10.5530/001954641318 · 2023

Background: Atovaquone are important drugs that are used in the treatment of malaria and in combination with mefloquine hydrochloride increases the efficacy and potency. Present study covers the development of UV-spectro…

Poonam Patil, Tara Shankar Basuri, Sonal Desai

pp. 264–270 · DOI: 10.5530/0019546402522 · 2023

Background: The goal of proposed study was to optimize and validate reversed phase high performance liquid chromatography (RP-HPLC) method for assessment of eluxadoline in presence of its forced degradation products in i…

Basavaraj Hiremath, Nagesh Gunavanthrao Yernale, Mahadev Dhanraj Udayagiri

pp. 271–277 · DOI: 10.5530/001954640247 · 2023

Aim: Cefpirome (CFP) in pure and pharmaceutical dosage forms determination by spectrophotometer; two very sensitive techniques have been developed. Materials and Methods: By mixing alkaline β-Naphthol (2-NPL) with diazot…

Miglena Smerikarova, Stanislav Bozhanov, Vania Maslarska

pp. 278–285 · DOI: 10.5530/001954641926 · 2023

Background: Transthyretin amyloidosis is a rare disease currently under wide investigation and many different therapeutic agents were developed for its control and treatment. In addition to the newly discovered drugs, it…

Jovana Ilkić, D. Obradović, Andrijana Milošević Georgiev, Valentina Marinković, Ivana Tadić

pp. 286–294 · DOI: 10.5530/001954641895 · 2023

Aim/Background: COVID-19 pandemic has casted a new light over the capacity of telepharmacy to increase access to pharmaceutical care, providing more support to patients and allowing new opportunities for pharmacists. How…

Manoj Kumar Vashisth, Yu Mi, Xiaolin Ye, Xiumei Wu, Zhizhong Mi, Xianzhang Tian, Bensi Zhang

pp. 295–300 · DOI: 10.5530/001954641962 · 2023

Background: In various human postural studies, foot is considered to be a rigid body. The flat foot, also referred to as the acquired disorder of the flat foot, results from the subsidence of the arches of the feet. Usua…

Srividya Ravi, Sammita Jadhav, Ravindra Ghooi

pp. 301–307 · DOI: 10.5530/001954641939 · 2023

Introduction: Repurposed drugs are not eligible for patent protection in India vide Sec 3 (d) of the Indian Patent Act, 1970. The data generated to establish the therapeutic efficacy of the repurposed drugs for the new i…

Valliappan Kannappan

pp. 308–309 · DOI: 10.5530/001954640002 · 2023

The Pharmacy degree course curriculum marks the most crucial stage of conventional pedagogy because specialized discipline-based, content-oriented courses in pharmaceutical and allied areas of knowledge are introduced at…