Volume 57, Issue 1

Swadesh Kumar Pattanik, Kishanta Kumar Pradhan

pp. 1–14 · DOI: 10.5530/001954642291 · 2023

Background: Reactive oxygen species mediate oxidative stress, is one of the major causes of the athero-thrombotic process involved in the etiology of peripheralarterial disease, ischemic strokes, and heart attack. Angiot…

Ankita Borse, Nirmala Shinde, Sachin Kawaduji Bhosale

pp. 15–21 · DOI: 10.5530/001954640093 · 2023

Dipeptide conjugates and conjugates of amino acids with heterocycles or other chemical entity are significant class of medicinal compounds with a wide range of biological actions including antibacterial, antiviral, antic…

Chandra Kishore Tyagi, Vaibhav Tripathi

pp. 22–27 · DOI: 10.5530/001954641253 · 2023

Introduction: Generally, animal models are regarded as very useful tools for studying pathophysiology and the clinical aspects of the disease and are always used as the first step for investigating a prospective new ther…

Weihua Chu

pp. 28–32 · DOI: 10.5530/001954641319 · 2023

Background: Pharmaceutical microbiology is an important applied branch of microbiology and it’s provided broad knowledge and understanding with regards to the principles, techniques and processes involved in pharmaceutic…

Uday Kumar Thummala, Eswar Gupta Maddi, Prameela Rani Avula

pp. 33–44 · DOI: 10.5530/001954641530 · 2023

Background: Fast-dissolving tablets (FDTs) were aimed to be developed for the latest approved combination drugs for Hepatitis-C treatment, Ledipasvir (LDV) and sofosbuvir (SBV) which suffered with poor water solubility. …

Rashed M. Almuqbil

pp. 45–52 · DOI: 10.5530/001954640001 · 2023

Aim: This study aimed to extract pectin from Citrus limon, synthesize thiolated pectin (TFP), and assess its mucoadhesion capability utilizing in-vitro and ex-vivo methodologies. Materials and Methods: Wilhelmy`s approac…

Ashish Y Pawar, Khanderao R Jadhav, Sharayu P Rathod, Ashwini S Sanap, Milind J Umekar

pp. 53–61 · DOI: 10.5530/001954641980 · 2023

Objectives: The objective of the research is to formulate a nanosponges loaded hydrogel of Metformin Hydrochloride for the treatment of Psoriasis. Psoriasis is currently treated with a variety of topical and systemic the…

Regulagadda Suryanarayana, Anjaneyulu Vinukonda, Seema Saroj, Neelu Jain, Harish Pandey, VSA Pavan Rudrabhatla, Thrimurthulu Gode

pp. 62–73 · DOI: 10.5530/001954641874 · 2023

Introduction: Nasal route is an alluring route for direct drug delivery to the central nervous system (CNS), owing to its avoidance of the hepatic first-pass metabolism and deciphering the blood–brain barrier passage iss…

Mengmeng Wang, Hongmei Xia, Xinying Yang, Qin Zhang, Yufan Li, Yu Wang, Ying Xia, Zili Xie

pp. 74–82 · DOI: 10.5530/001954642087 · 2023

Aim: Berberine hydrochloride is a Traditional Chinese Medicine component with antibacterial, antiviral, anti-inflammatory, antioxidant and lowering blood sugar effects. However, the application of berberine hydrochloride…

Priya Palanivelu, Vijayakumar Jagadesan, Rajagopalan Vijayaraghavan, Praveenkumar Parthiban, Madhankumar Swaminathan, Senthilkumar Sivanesan

pp. 83–93 · DOI: 10.5530/001954641032 · 2023

Objectives: The aim of the present study was to examinethe protective effect of bark extract of TA (Terminalia arjuna) on HFD (high fat diet) induced biochemical and histopathological changes in Wistar rats. Materials an…

Rakesh Kumar, Gurinder Kaur, Atamjit Singh, Jaijeet Singh, Balbir Singh, Sarabjit Kaur

pp. 94–100 · DOI: 10.5530/001954641261 · 2023

Introduction: With a tremendous spike in the cases of anxiety in recent years, scientists are looking for herbal drug alternatives for its treatment as all the conventional medication options available in the market have…

Nutan Kendre, Pravin Wakte

pp. 101–106 · DOI: 10.5530/001954641137 · 2023

Aim: The purpose of this paper was to develop a sensitive, reproducible Reverse Phase High Performance Liquid Chromatography (RP-HPLC) for extraction and quantitative estimation of Scutellarein, major flavone glycoside f…

Horacio Larqué, Eugenio Sánchez-Arreola, Gregorio Arellano-Ostoa, Luis R. Hernández, Horacio Bach, Abelardo Chávez-Montes

pp. 107–112 · DOI: 10.5530/001954641346 · 2023

Introduction: Mexican artisans use the linaloe tree for the production of handcrafts. The extracted oil from the endangered Mexican tree Bursera linanoe which main components are the terpenes linalol and linalyl acetate …

Abdullah A. Al-Ghanayem

pp. 113–119 · DOI: 10.5530/001954641705 · 2023

Aim: To determine the antifungal and antibiofilm activity of Cymbopogon flexuosus (Lemongrass oil) against C. parapsilosis and C. tropicalis. Materials and Methods: Lemongrass oil, was analyzed by GC-MS. Antifungal activ…

Gayathri Somashekar, Uma Sudhakar, Seshadri Srividya, Snophia Suresh

pp. 120–124 · DOI: 10.5530/001954641931 · 2023

Background: Ormocarpum cochinchinense is a medicinal herb known to be used by traditional bone setters for the healing of bone fractures. This herb has many active biomolecules, which are responsible for biological activ…

Rezarta Shkreli, Rihana Terziu, Lorena Memushaj, Klodiola Dhamo, Ledjan Malaj

pp. 125–133 · DOI: 10.5530/001954642109 · 2023

Background: Essential oils are currently the subject of intensive scientific study, and their potential as active medicinal compounds or natural preservatives has attracted the attention of the cosmetic and pharmaceutica…

Junhong Wan, Qian Xu, Tahani Awad Alahmadi, Prabakaran DS, Min Liu

pp. 134–140 · DOI: 10.5530/001954642201 · 2023

Background: Acute kidney injury (AKI) is a heterogenous condition, characterized by dysregulated kidney function along with reduced glomerular filtration, solute excretion, and urine output. Objectives: This work was foc…

Bahareh Bakhshi, Sudhakar Malla, S Lokesh

pp. 141–146 · DOI: 10.5530/001954642708 · 2023

Objectives: In this study, we focus on the amount of the two defence enzymes phenylalanine ammonia-lyase (PAL) and peroxidase (POX) expressed with regard to the treatment of green synthesized silver nanoparticles. Materi…

Danni Li, Xiaoxiao Man, Xiaoxia Ma, Jinbo Sun

pp. 147–154 · DOI: 10.5530/001954642194 · 2023

Background: Alzheimer’s disease is a prevalent neurodegenerative condition marked by the assembly of ß-amyloid deposits inside the brain parenchyma. Aluminium is a neurotoxin molecule that generates oxidative stress link…

Wenyan Ying, Tongbing Qi, Dongzi Shi, Jing Zhang, Ganghui Ye, Xuewen Tian, Qinglu Wang

pp. 155–160 · DOI: 10.5530/001954641252 · 2023

Background: Methylmercury (MeHg), manganese ions (Mn2+), and lead ions (Pb2+) are ubiquitous environmental pollutants and may be neurotoxic especially during fetal development. We decided to explore the toxic mechanisms …