Volume 58, Issue 1

Kamran Ashraf, Nur Fatin Adlin, Aina Nabila Basri, Wasim Ahmad, Sadia Sultan

pp. 1–14 · DOI: 10.5530/ijper.58.1.1 · 2024

Clitoria ternatea (Family: Fabaceae) is an important medicinal plant in traditional folk medicine. This plant was found to contain various types of metabolites. Many different pharmacological effects, including antioxida…

Aman Shrivastava, Jeetendra Kumar Gupta

pp. 15–20 · DOI: 10.5530/ijper.58.1.2 · 2024

Cannabinoids interact with Cannabinoid Receptors (CBRs) and some related non-cannabinoid transcription factors within neurological and non-neuronal-specific receptors. The current review has covered pharmacological molec…

Haranath Chinthaginjala, Varalakshmi Bogavalli, Abdul Ahad Hindustan, Jayasree Pathakamuri, Sai Sree Pullaganti, Aswini Gowni, Bandhavi Baktha

pp. 21–33 · DOI: 10.5530/ijper.58.1.3 · 2024

Nanotechnology is rapidly evolving in the development of new drug delivery systems. Nanostructured lipid carriers are the second era of Solid Lipid Nanoparticles (SLN). These are the alternative carrier system over the s…

Kajal Barge, Shivali Tank, Bhagyashri Parab, Mangal Nagarsenker, Supriya Shidhaye

pp. 34–44 · DOI: 10.5530/ijper.58.1.4 · 2024

Lifestyles and environmental changes draw people away from healthy and natural-looking skin. To hide the impaired and damaged skin texture as a result of several factors, people mostly prefer decorative cosmetics to get …

Suraj Mandal, Km. Bhumika, Mukesh Kumar, Jiyaul Hak, Prabhakar Vishvakarma, Umesh Kumar Sharma

pp. 45–63 · DOI: 10.5530/ijper.58.1.5 · 2024

Microsponges are porous microspheres ranging in size from 5 to 300 micrometers used in a polymeric delivery system. They have been studied for biomedical applications, including targeted medicine delivery, transdermal dr…

Peirong Chen, Bingjie Ma, Jinni Liu, Min Zhang, Jinzhe Li, Haigang Wu

pp. 64–68 · DOI: 10.5530/ijper.58.1.6 · 2024

Homeostasis of the animal gut microbiome is essential for maintaining intestinal health and normal growth and development. Baicalin is an O-glucuronidated flavonoid that possesses strong anti-bacterial, anti-inflammatory…

Omotejohwo Emily Okolosi-Patani, Ufuoma David Adje, John Ejophe Arute, Ufuoma Shalom Ahwinawhi

pp. 69–75 · DOI: 10.5530/ijper.58.1.7 · 2024

Background: To assess the self-reported quality of education received by undergraduate pharmacy students and to explore factors influencing career choice. Materials and Methods: A pretested questionnaire was administered…

Vedanshu Malviya, Srikant Pande

pp. 76–90 · DOI: 10.5530/ijper.58.1.8 · 2024

Introduction: Nasal medication delivery uses nasal mucosa for faster and higher drug absorption. Transmucosal nasal administration is promising. Many medicines obtain superior systemic absorption via nasal route than ora…

Jawaher Abdullah Alamoudi, Yosif Almoshari, Hadil Faris Alotaibi

pp. 91–98 · DOI: 10.5530/ijper.58.1.9 · 2024

Objectives: This study aims to prepare a topical cubosomal formulation that contains 5-Fluorouracil (5-FU), a hydrophilic anti-cancer drug, that belongs to the Biopharmaceutics Classification System (BCS-III) i.e., high …

Varsha Bandil, Jeetendra Kumar Gupta, Manoj Kumar Goyal

pp. 99–108 · DOI: 10.5530/ijper.58.1.10 · 2024

Background: The prime objective of our investigation was to optimize PLGA-chitosan nanoparticles containing vinorelbine ditartrate. Materials and Methods: The Vinorelbine ditartrate nanoparticles were formulated using em…

Hafiz A. Makeen, Mohammad Albratty

pp. 109–121 · DOI: 10.5530/ijper.58.1.11 · 2024

Aim: The current research was performed for the preparation and optimization of Transniosomes (TN) preparation for the dermic distribution of Ursolic Acid (UA). Materials and Methods: The formulation was optimized by usi…

Sandeep Ghangas, Praveen Kumar Ashok, Tanuj Hooda

pp. 122–130 · DOI: 10.5530/ijper.58.1.12 · 2024

Aim/Background: The objective of this research was to develop a nano-emulsified formulation by using a central composite design for topical drug delivery. Materials and Methods: Isotretinoin-loaded nano-emulsified drug d…

Girish Meravanige, Ranjitha B, Prakash Goudanavar, GSN Koteswara Rao, B Nirmala Devi, N. Raghavendra Naveen, Afzal Haq Asif, Sree Harsha Nagaraja, Mohammed Monirul Islam, Pavan Kumar Pavagada Sreenivasalu, Mallikarjun Telsang, Krishna Swaroop Duddi Sreehari

pp. 131–138 · DOI: 10.5530/ijper.58.1.13 · 2024

Background: The topical administration of antifungal drugs by Solid Lipid Nanoparticles (SLNs) has enormous potential. This study aimed to develop a topical 5-flucytosine-loaded SLNs gel to improve the efficacy of the we…

Ying Zhao, Qinqin Sun

pp. 139–144 · DOI: 10.5530/ijper.58.1.14 · 2024

Background: Nursing care of diabetic wounds remains a significant challenge due to a variety of reasons including low blood flow, impaired activity of inflammatory responses, and high oxidative stress in the diabetic wou…

Ahmed Reda Belmamoun, Abdelkader Ammam, Chafik Mhamdia, Redouane Chadli, Afaf Baki, Abdenacer Tou, Hafidh Zemour, Didier Villemin, Walid Soufan, Fathi Abdellatif Belhouadjeb

pp. 145–153 · DOI: 10.5530/ijper.58.1.15 · 2024

Background: Our study evaluated the effect of Chrysanthemum coronarium L. (CC) leaves on ethanol-induced acute gastric ulcers in Wistar rats. Materials and Methods: The organic extract of CC was obtained by Soxhlet extra…

Abdulaziz S. Alothaim

pp. 154–161 · DOI: 10.5530/ijper.58.1.16 · 2024

Background: Cancer is ranked among the world's leading causes of death in 2020 with an estimated 10 million recorded fatalities attributable to the disease. After breast, colorectal, and lung cancer, cervical cancer is t…

Sanjita Das, Saumya Das, Sakshi Pal

pp. 162–171 · DOI: 10.5530/ijper.58.1.17 · 2024

Aim: The aim of the current research is the evaluation of immunomodulatory and anti-asthmatic activity of Actinidia deliciosa on Swiss albino mice by using a number of experimental models. Materials and Methods: The immu…

Meesala Guru Sekhar, Kondeti Ramudu Shanmugam, Kanchi Siva Prasad, Ramakrishna Chilakala

pp. 172–177 · DOI: 10.5530/ijper.58.1.18 · 2024

Aim: Alcoholism leads to heart diseases, lung diseases and liver disorders. Alcoholism impairs heart homeostasis and causes cardio vascular diseases. The current investigation was carried out to know the hypolipidemic ef…

Gobika Arumugam, Sangilimuthu Alagar Yadav

pp. 178–186 · DOI: 10.5530/ijper.58.1.19 · 2024

Introduction: Resveratrol, Epigallocatechin -3-gallate (EGCG) and Diallyl Trisulfide (DATS) are bioactive compounds in which two polyphenols and an organosulfur are naturally occurring bioactive chemicals that can be eff…

Orhan Polat, Turan Yaman, Ahmet Ufuk Kömüroğlu

pp. 198–203 · DOI: 10.5530/ijper.58.1.21 · 2024

Background: The aim of the present study was to investigate the hepatoprotective effect of Shepherd's Purse (SP) herbal tea on ethanol (EtOH)-induced liver toxicity. Materials and Methods: Male Wistar rats (n = 32) were …