Volume 52, Issue 4S

2018 · pp. s119–s123 · 46 articles

Volume: 52
Issue: 4S
Published: 2018
Pages: s119–s123
Articles: 46
Sections: 3
ISSN: Online - 0019-5464
Journal: IJPER

Review Article Original Article Research Article

In this issue

Review Article

Review
OSCE-A New Assessment Method for Pharmaceutical Education
Amit Vanka, Othman Wali, Butchi Raju Akondi, Shanthi Vanka, Sreeja Ravindran
pp. s1–s6 · DOI: 10.5530/ijper.52.4s.68 · Published 2018
More reliable and validated method of assessment is the need of the hour for better summative evaluation of the students of pharmaceutical sciences. Competency or outcome based education models rely heavily on assessment…
Review
Bridging the Gap Between Industry and Academia in Pharmaceutical Education
Athira Balakrishnan, Girish Thunga, Sreedharan Nair, Vijayanarayana Kunhikatta, Kanav Khera
pp. s7–s10 · DOI: 10.5530/ijper.52.4s.69 · Published 2018
Though Pharmaceutical industries are growing at a rapid rate, Pharmacy curriculum is not taken pharmaceutical industry into consideration. Both industry and academia have different mindsets and goals. Pharma curriculum i…
Review
Potential Antithrombotic Effect of Crataegus Species
Rana Arslan, Nurcan Bektas
pp. s155–s157 · DOI: 10.5530/ijper.52.4s.93 · Published 2018
Hawthorn (Crataegus), a highly important medicinal and aromatic plant, has been used for many years in the treatment of various diseases. In folk medicine, hawthorn has been used to treat asthma, hyperlipidemia, heart fa…

Original Article

Article
Impact of Concomitantly Administered Curcumin on Pharmacokinetics of Daclatasvir in Mice Under the Frame of Herb-Drug Interaction
Asmita Magotra, Pankul Kotwal, Shipra Bhatt, Ashish Dogra, Gurdarshan Singh, Utpal Nandi
pp. s11–s15 · DOI: 10.5530/ijper.52.4s.70 · Published 2018
Objective:Daclatasvir is a new orally acting antiviral drug for the treatment of hepatitis C virus (HCV). It is substrate of both P-glycoprotein (P-gp) and CYP3A4 which are involved in the major pharmacokinetic interacti…
Article
Development of Fluconazole Suppositories for the Treatment of Candida Infection of Genitourinary Tract
R. Saketh Reddy, Lalit Kumar, Chinna Raja Pydi, M. Sreenivasa Reddy, Ruchi Verma
pp. s16–s22 · DOI: 10.5530/ijper.52.4s.71 · Published 2018
Background: Vulvovaginal candidiasis is a communal problem in virtually all the women which is caused by Candida albicans. Objective: Aim of the present study was to prepare and characterize vaginal suppositories of fluc…
Article
Simultaneous Determination of Some 5-Nitroimidazole Derivatives and Ciprofloxacin by High Performance Liquid Chromatography
Stanislav Bozhanov, Vania Maslarska, Boyka Tsvetkova, Lily Peikova
pp. s23–s28 · DOI: 10.5530/ijper.52.4s.72 · Published 2018
Objective: An isocratic high performance liquid chromatographic method for simultaneous determination of Metronidazole, Tinidazole and Ciprofloxacin was developed. Method: Separation was achieved with a C18 (250x4.6 mm, …
Article
Diosmin Phytosomes: Development, Optimization and Physicochemical Characterization
Prachi P Udapurkar, Omprakash G Bhusnure, Santosh R Kamble
pp. s29–s36 · DOI: 10.5530/ijper.52.4s.73 · Published 2018
Background: Diosmin is a flavonoids glycoside that possesses different therapeutic activity include vascular-protecting agent used to help improving chronic venous insufficiency (CVI), haemorrhoids, etc. Diosmin is bioac…
Article
Simultaneous Quantitative Determination of Bupropion and its Metabolites by High Performance Liquid Chromatography Tandem Mass Spectrometry Detection: Application to Bioequivalence Study
Pradeep Kumar Shahi, Haresh Patel, Vishal Shah, Ashutosh Bhokari, Rajamannar Thennati, Rakshit Ameta
pp. s37–s46 · DOI: 10.5530/ijper.52.4s.74 · Published 2018
Objective:A rapid, selective, sensitive, precise and accurate liquid chromatography in tandem with electro-spray ionization mass spectrometry method has been developed and validated for the simultaneous quantification of…
Article
Synchronous Estimation of Glycopyrrolate and Formoterol in Bulk and Pharmaceutical Dosage Form by RP-HPLC Method
Kishor Kumar Erukulla, Suseem Sundaram Rengitham
pp. s47–s55 · DOI: 10.5530/ijper.52.4s.75 · Published 2018
Objective:The objective is to develop and validate a fundamental, specific, novel and exact RP-HPLC (Reverse phase-High performance Liquid chromatography) methodology for the synchronous determination of Glycopyrrolate a…
Article
Development of a Validated Stability Indicating Liquid Chromatographic Method for the Determination of Pterostilbene
Mukthinuthalapati Mathrusri Annapurna, Bukkapatnam Venkatesh, Gunnam Ravi Teja
pp. s63–s70 · DOI: 10.5530/ijper.52.4s.77 · Published 2018
Introduction: Pterostilbene, a stilbenoid possess diversified pharmacological activities. In the present study, a stability-indicating liquid chromatographic method was proposed for the determination of Pterostilbene in …
Article
Cypermethrin-Induced in vitro Alterations on Oxidative Stress and Quality of Salmo coruhensis Spermatozoa
Filiz Kutluyer, Mehmet Kocabaş, Mine Erişir, Fulya Benzer
pp. s71–s76 · DOI: 10.5530/ijper.52.4s.78 · Published 2018
The use of insecticides has been increasing along with increasing agriculture activities and has caused deleterious environmental impacts. Non-target organisms in particular, including fish, are affected by pesticides. I…
Article
Neuroprotective Functions of Alpinia galanga in Forebrain Ischemia Induced Neuronal Damage and Oxidative Insults in Rat Hippocampus
Ravi Mundugaru, Senthilkumar Sivanesan, Padmaja Udaykumar, Vidyadhara D J, Suchitra Narayan Prabhu, Basavaiah Ravishankar
pp. s77–s85 · DOI: 10.5530/ijper.52.4s.79 · Published 2018
Introduction: The rhizomes of Alpinia galanga (L.) Willd (Zingiberaceae) commonly known as greater galangal, a ginger substitute for food and was traditionally used as nervine tonic and stimulant. The present study was d…
Article
Seasonal Changes of Phagocytic Activity Enhanced by an Acoholic Mint Extract in Cultured Rainbow Trout
Spînu Marina, Pall Emoke, Niculae Mihaela, Vasiu Aurel, Brudaşcă Gheorghe Florinel, Cerbu Constantin Gheorghe, Negrutiu Vlad, Vasiu Constantin, Silvana Popescu, Sandru Carmen Dana
pp. s86–s90 · DOI: 10.5530/ijper.52.4s.80 · Published 2018
Objective:We hypothesized that leukocyte numbers and their in vitro phagocytic activity in farmed rainbow trout are subject to negative influence of extreme temperatures for fish and that mint extract could alleviate the…
Article
Prolonged in vivo Stinging Nettle Treatment Impacts on Functional Capacity of Leukocytes in Immunologically Mature Chickens
Șandru Carmen Dana, Niculae Mihaela, Pall Emoke, Brudaşcă Florinel, Vasiu Aurel, Silvana Popescu, Cerbu Constantin, Giupana Radu, Vasiu Constantin, Valentin Tudor, Spînu Marina
pp. s91–s95 · DOI: 10.5530/ijper.52.4s.81 · Published 2018
Objective:The experiment aimed at establishing the effects of an alcoholic Urtica dioica extract on the in vitro blastogenic response in antigen stimulated, immunologically mature chickens. Materials and Methods: Three e…
Article
Antioxidant Capacity and Bioactive Contents of Mulberry Species from Eastern Anatolia Region of Turkey
Muttalip Gundogdu, Murat Tunçtürk, Selma Berk, Nazım Şekeroğlu, Sevgi Gezic
pp. s96–s101 · DOI: 10.5530/ijper.52.4s.82 · Published 2018
In this study, we aimed to determine biochemical contents of white (Morus alba L.) and black (Morus nigra L.) mulberry genotypes grown in the Hakkari region. At the end of the study, organic acids, phenolic compounds, su…
Article
Essential Oil Composition of Some Sage (Salvia spp.) Species Cultivated in İzmir (Turkey) Ecological Conditions
Ünal Karik, Orçun Çinar, Murat Tunçtürk, Nazım Şekeroğlu, Sevgi Gezici
pp. s102–s107 · DOI: 10.5530/ijper.52.4s.83 · Published 2018
Background: Salvia L., the largest genus of Lamiaceae, includes about 1000 species, widespread throughout the world. This genus is represented, in Turkish flora, by 99 species and 113 taxa, 58 of which are endemic. Some …
Article
Effect of Cadmium Application on Antimicrobial, Antioxidant and Total Phenolic Content of Basil Genotypes
Kürşat Korkmaz, Ömer Ertürk, Melek Çol Ayvaz, Mehmet Muharrem Özcan, Mehmet Akgün, Ayşegül Kirli, Duygu Odabaş Alver
pp. s108–s114 · DOI: 10.5530/ijper.52.4s.84 · Published 2018
Background: Exposure to heavy metals leads to increase in reactive oxygen species. Plants have many strategies to counteract the toxic effects of heavy metal stress by activating certain intermediary metabolic activities…
Article
Effect of Led Drying on Drying Behavior of Prunus domestica L. Fruit
Mithat Akgün, Levent Kandemir, Burhan Öztürk
pp. s115–s118 · DOI: 10.5530/ijper.52.4s.85 · Published 2018
Background: Energy efficiency is becoming increasingly important in storing foods preserving their own characteristics and fruits and vegetables by drying in terms of selflife as well. Objectives: Since the Black Sea Reg…
Article
An in vitro Study of Cytotoxic Activity of Euphorbia macroclada boiss on Mcf–7 Cells
Ayça Taş, Serap Şahin-Bölükbaşı, Esranur Çevik, Esma Özmen, Erkan Gümüş, Yavuz Siliğ
pp. s119–s123 · DOI: 10.5530/ijper.52.4s.86 · Published 2018
Objective:The study was aimed to evaluate the cytotoxic activity of acetone extract of leaves, flower and body of Euphorbia macroclada boiss on human breast cancer cell line (MCF-7). Material: The cells were plated at a …
Article
The Physical, Chemical and Antioxidant Properties of the Leafs of Chaerophyllum byzantinum Boiss. Plants
Ilkay Koca, Belkis Tekguler, Volkan Arif Yilmaz
pp. s124–s127 · DOI: 10.5530/ijper.52.4s.87 · Published 2018
Objective: Chaerophyllum byzantinum Boiss. is a plant which is popularly consumed in the Black Sea Region/Turkey. In spring, the leafs of the plant are mainly used for soup making. This study was carried out in order to …
Article
Assessment of Antioxidant Activity of Giant Snowdrop (Galanthus elwesii Hook) Extracts with Their Total Phenol and Flavonoid Contents
Ebru Bati Ay, Melek Gül, M. Akif Açikgöz, Tarik Yarilgaç, Ş. Metin Kara
pp. s128–s132 · DOI: 10.5530/ijper.52.4s.88 · Published 2018
Background: The aim of this study was to determine total phenolic and flavonoid contents and antioxidant activities of Giant Snowdrop (Galanthus elwesii Hook). Objective: Giant Snowdrop, the second most common snowdrop i…
Article
Detection of the Genotoxicity of Gentiana L. Extracts by Using RAPD-PCR and ISSR-PCR Techniques
İlham Eröz Poyraz, İsmail Poyraz, H. Tuba Kıyan, Nilgün Öztürk, Serdar Erken, Fatih Gülbağ, M. Ercan Özzambak
pp. s133–s139 · DOI: 10.5530/ijper.52.4s.89 · Published 2018
Background: The RAPD- and ISSR-PCR techniques are offering an insight into the detecting the genotoxicity of Gentiana extracts. Objective: It is aimed with the present study, to detect the genotoxicity of methanol extrac…
Article
Enhancement of Phytochemical Compounds Using Biotic and Abiotic Elicitors in Purple Coneflower (Echinacea purpurea L.)
Muhammed Akif Açikgöz, Tarık Yarılgaç, Şevket Metin Kara
pp. s140–s145 · DOI: 10.5530/ijper.52.4s.90 · Published 2018
Background: Phytochemicals also known secondary metabolites, naturally occurring in medicinal and aromatic plants, are of considerable importance for plant survival and human health. Objective: The objective of this stud…
Article
Development of Geospatial Model for Preparing Distribution of Rare Plant Resources Using UAV/Drone
Takashi Watanabe, Aedla Raju, Yasuhide Hiraga, Koji Sugimura
pp. s146–s150 · DOI: 10.5530/ijper.52.4s.91 · Published 2018
Background: The study of functioning of ecosystems is significant with understanding the composition and distribution of plant resources at spatial and temporal scales. For comprehensive plant survey, the traditional met…
Article
Use of Medicinal and Aromatic Plants in Therapeutic Gardens
Mükerrem Arslan, Zeynep Kalaylioglu, Erdi Ekren
pp. s151–s154 · DOI: 10.5530/ijper.52.4s.92 · Published 2018
Introduction: Today there is an accumulation of literature providing evidence for long and short term beneficial effects of living close to nature on various different health conditions ranging from psychological to phys…
Article
Preparation and Characterization of Silymarin Nanocrystals and Phytosomes with Investigation of their Stability using Gamma Irradiation
Ahmed Ibrahim El-Batal, Shahira F Elmenshawi, Ahmed M Abdelhaleem Ali, Enas Goodha Eldbaiky
pp. s174–s183 · DOI: 10.5530/ijper.52.4s.96 · Published 2018
Introduction: In this study, Silymarin exhibits poor water solubility so, we developed drug delivery system. Different formulation strategies have been proposed for this problem. Materials and Methods: We were study the …
Article
Insertion of Dual Drugs of Hypertension in Gelatin Pockets for Chrono pharmacotherapy and its Evaluation by in-vitro and ex- vivo Studies
Madhuri Desavathu, Pathuri Raghuveer, Pallikonda Sarada
pp. s184–s196 · DOI: 10.5530/ijper.52.4s.97 · Published 2018
Objective:The project was aimed to fabricate and evaluate a pulsatile capsule to program the release of dual antihypertensive drugs to mimic the circadian pattern of Blood Pressure. The formulation was optimized to repea…
Article
Development of Ketoconazole Shampoo with Dipterocarpus alatus Oil as a Permeation Enhancer
Daodee Supawadee, Monthakantirat Orawan, Chulikhit Yaowared, Punya Thanakorn
pp. s197–s201 · DOI: 10.5530/ijper.52.4s.98 · Published 2018
Purpose:To develop and evaluate a model ketoconazole shampoo that includes Dipterocarpus alatus oil as a natural permeation enhancer. Methods: Model shampoos containing ketoconazole, D. alatus oil (1-3% v/v), sodium laur…
Article
Chitosan Loaded Ketorolac Tromethamine Nanoparticles for Improved Ocular Delivery in Eye Inflammation
Shaweta Sharma, Akhil Sharma, Udayveer Singh Sara, Shekhar Singh
pp. s202–s209 · DOI: 10.5530/ijper.52.4s.99 · Published 2018
Aim: Ketorolac tromethamine (KT) is highly effective in treating post-operative eye inflammation, allergic conjunctivitis as well other ailments. It is reported that USFDA has approved a 0.45% ophthalmic solution of KT (…
Article
Evaluation of Comparative Immunomodulatory Potential of Solanum xanthocarpum Root and Fruits on Experimental Animal
Ravindra Kumar Pandey, Shiv Shankar Shukla, Anurekha Jain, Avijeet Jain, Vipin Bihari Gupta, Lokesh Deb
pp. s237–s245 · DOI: 10.5530/ijper.52.4s.103 · Published 2018
Aim: This study was aimed to justify the scientific basis in folklore use of Solanum xanthocarpum (solanaceae) as an Immunomodulatory agent in India. Materials and Methods: The ethanol and aqueous extracts of S. xanthoca…
Article
Phytotoxic, Cytotoxic and Insecticidal Activities of Chrysophthalmum dichotomum Boiss. and Heldr.
Fatma Ayaz, Nurg n K kboyac, Bar Bani, Bilge ener, Muhammad Iqbal Choudhary
pp. s252–s256 · DOI: 10.5530/ijper.52.4s.105 · Published 2018
Background: Chrysophthalmum dichotomum Boiss. and Heldr. (Asteraceae) is an endemic herbaceous plant to Southern part of Turkey. Aim: To investigate in vitro phytotoxic, cytotoxic and insecticidal activities of C. dichot…
Article
Agreement between Creatinine and Cystatin C-Based Equations in the Estimation of Glomerular Filtration Rate among Malaysian Patients with Renal Impairment
Nor Asyikin Mohd Tahir, Abdul Halim Abdul Gafor, Farida Hanim Islahudin, Shamin Mohd Saffian, Hamizah Abdul Manan, Hanita Othman, Mohd Makmor-Bakry
pp. s257–s267 · DOI: 10.5530/ijper.52.4s.106 · Published 2018
Background: Cystatin C-based equations have been proposed as an alternative for creatinine-based equations in the estimation of Glomerular Filtration Rate (eGFR). Limited studies were available with regards to the Asian …
Article
Pharmacophore and Atom Based 3D QSAR Studies on the Novel 5-Alpha-Reductase Inhibitors
Abhishek Shah, Richard Lobo, Nandakumar Krishnadas, Aravinda Pai
pp. s296–s302 · DOI: 10.5530/ijper.52.4s.110 · Published 2018
Aim/Background: The anomalous production of dihydrotestosterone (DHT) observed in benign prostatic hyperplasia and prostate cancer particularly in tissues of the prostate gland. The primary male sex hormone, testosterone…
Article
Development of Novel Dynamic Drop-to-Drop Microextraction Coupled with GC-MS for the Trace Level Screening of Phenothiazine Drug in Human Biological Samples
Pratik Kumar Jagtap, Kavita Tapadia
pp. s303–s308 · DOI: 10.5530/ijper.52.4s.111 · Published 2018
A novel analytical technique of dynamic drop-to-drop solvent microextraction (DDSME) is developed to determine phenothiazine drug promethazine commonly used in cough syrups and in aesthetic drinks, purple drank most comm…
Article
Quinazoline Derivatives as Anticancer Agents: QSAR, Molecular Docking and in silico Pharmacokinetic Prediction
Siddharth Jitendrakumar Modi, Vithal Madhvarao Kulkarni
pp. s309–s325 · DOI: 10.5530/ijper.52.4s.112 · Published 2018
Context:Molecular target specific treatment for the cancer is different from the conventional chemotherapy and radiotherapy in terms of selectivity and specificity towards the cancer cells. Amongst the different molecula…
Article
Evaluation of Neuroprotective Potential of Some Newly Synthesized Benzopyran-2-One Derivatives in Swiss Albino Mice
Arif Hussain Tippu, Imaduddin Mohammed
pp. s326–s332 · DOI: 10.5530/ijper.52.4s.113 · Published 2018
Background: Present study was carried out to evaluate neuroprotective activity of newly synthesized Benzopyran-2-one derivatives. Methods: Three compounds namely 7-(2-(o-furan)-phenyl thiazolidinyl)-4-methyl benzopyran-2…
Article
Design, Synthesis, Antioxidant and Anticancer Activity of Novel Schiff’s Bases of 2-Amino Benzothiazole
D. Saipriya, Arun Prakash, Suvarna G Kini, Varadaraj Bhatt G, K Sreedhara Ranganath Pai, Subhankar Biswas, Mohammed Shameer K
pp. s333–s342 · DOI: 10.5530/ijper.52.4s.114 · Published 2018
Introduction: Around 5,00,000 women are affected by cervical cancer and nearly half of them end up losing the battle of life with this deadly disease. So, there is an urgent need for the synthesis and development of new,…

Research Article

Article
Role of Communication Skill and Good Documentation Practice in the Overall Development of the Pharmacy Graduates in India: An Observational Study with Classroom Record-Daily Laboratory Record-Human Resource Record (CR-DR-HR) Model
Akhilesh Dubey, Ravi Ravi Gundadka Shriram, Srinivas Hebbar, Chakrakodi Shashidhara Shastry, Rompicherla Narayana Charyulu
pp. s158–s163 · DOI: 10.5530/ijper.52.4s.94 · Published 2018
Objective:The aim of this observational research study was to bring up the issues related to Communication skill (CS) and Good documentation practice (GDP) in one of the pharmacy college in India and its impact on the st…
Article
Community Pharmacists’ Perceptions and Experiences towards Values, Ethics and Decisionmaking: A Qualitative Study
Kingston Rajiah, Rajesh Venkataraman
pp. s164–s173 · DOI: 10.5530/ijper.52.4s.95 · Published 2018
Background: In Community Pharmacy, prescriptions, medical devices and other over the counter products are dispended by community pharmacists. Ethical issues do exist while dispensing medications based on prescription and…
Article
Formulation of Dispersed Gliclazide Powder in Polyethylene Glycol–Polyvinyl Caprolactam– Polyvinyl Acetate Grafted Copolymer Carrier for Capsulation and Improved Dissolution
Ather Ahmed Mahdi Dukhan, Nursazreen Amalina, May Kyaw Oo, Pinaki Sengupta, Abd Al Monem Doolaanea, Khater Ahmed Saeed Aljapairai, Bappaditya Chatterjee
pp. s210–s219 · DOI: 10.5530/ijper.52.4s.100 · Published 2018
Background: Oral bioavailability of gliclazide, a hypoglycemic drug, is hindered by its low aqueous solubility. Improvement of solubility will enhance dissolution rate and in turn the bioavailability. This research aimed…
Article
Development and Evaluation of Nevirapine Extended Release Tablets using QbD Approach
Vasantakumar Pai Karkala, Harsha Jinadatharaya, Devagowda Vishakante Gowda, Praveen Sivadasu Department o
pp. s220–s228 · DOI: 10.5530/ijper.52.4s.101 · Published 2018
Objective:To develop and evaluate Nevirapine (NVP) Extended release tablets for reducing the dosing frequency using Methylcellulose USP Methocel A15-LV and Hypromellose USP Methocel K4M Premium CR used as rate retarding …
Article
Impact of Surfactants on Formulation Parameters and in vitro Cytotoxicity of Boswellic Acids Loaded Nanoparticles on Human Colon Cancer Cell Lines
Neeta Solanki, Harish Dureja
pp. s229–s236 · DOI: 10.5530/ijper.52.4s.102 · Published 2018
Objective:Boswellic acids extracted from the gum resin of plant Boswellia serrata are well reported for anti-inflammatory and anticancer activities. The Present investigation was aimed to optimize the surfactant concentr…
Article
Chorioallantoic Membrane (CAM) Assay of Different Extracts of Rhizome and Inflorescence of Heliconia rostrata
Moonmun Dhara, Lopamudra Adhikari, Raja Majumder
pp. s246–s251 · DOI: 10.5530/ijper.52.4s.104 · Published 2018
Background: Rhizomes of Heliconia rostrata (Heliconiaceae) has antiophidic, in vitro antioxidant and antibacterial activity. Aim: Extracts of rhizome and inflorescence of H. rostrata were studied to test their angiogenes…
Article
Novel Quinolone Substituted Quinazolin-4(3H)-Ones as Anti-Inflammatory, Anticancer Agents: Synthesis and Biological Screening
Santosh Kumar, Jignesh Chhaganbhai Aghara, Angel Treasa Alex, Jesil Mathew Aranjani, Alex Joesph
pp. s268–s276 · DOI: 10.5530/ijper.52.4s.107 · Published 2018
Background: Quinolones and, quinazolinones are important pharmacodynamic heterocyclic nuclei which when incorporated into different heterocyclic templates, have been reported to possess potent anti-inflammatory and antic…
Article
Development and Validation of a LC-ESI-MS/MS Based Bioanalytical Method for Dapagliflozin and Saxagliptin in Human Plasma
Swapna Goday, Abdul Rahaman Shaik, Prameelarani Avula
pp. s277–s286 · DOI: 10.5530/ijper.52.4s.108 · Published 2018
Objective:To develop a new, rapid and sensitive LC-ESI –MS/MS method for the simultaneous estimation of Dapagliflozin and saxagliptin in human K2EDTA plasma by Liquid –liquid Extraction method (LLE) using deutereated dap…
Article
A LC/MS-MS Guided Isolation of Laccaic Acid-A: A Potent Antimicrobial Agent
Suddhasattya Dey, Manik Ghosh
pp. s287–s295 · DOI: 10.5530/ijper.52.4s.109 · Published 2018
Background: Lac is traditionally used as a dye because of its coloring properties and it is obtained from Laccifer lacca Kerr. Now a days, it is widely used in food and coloring industry. Purpose: To evaluate the antioxi…