Volume 58, Issue 4S

2024 · pp. s1271–s1281 · 16 articles

Volume: 58
Issue: 4S
Published: 2024
Pages: s1271–s1281
Articles: 16
Sections: 3
ISSN: Online - 0019-5464
Journal: IJPER

Guest Editorial Review Article Original Article

In this issue

Guest Editorial

Article
Research Planning, Statistical Analysis, Ethics, and Successful Publishing
Pitchai Balakumar, Renukha Sellappan, Shubhada Nagarkar, Avijit Hazra, Gowraganahalli Jagadeesh
pp. s1102–s1107 · DOI: 10.5530/ijper.58.4s.111 · Published 2024
Novice researchers are frequently inexperienced with basic concepts of research and successful scientific publishing. To strengthen their fundamental knowledge of scientific research, we recently conducted a brainstormin…

Review Article

Review
Bioactivities, Biopharmaceutics, and Advanced Drug Delivery Systems of Magnolol
Sabna Kotta, Bayan A. Eshmawi, Amerh Aiad Alahmadi, Hibah Mubarak Aldawsari, Shaimaa M. Badr-Eldin, Anroop B. Nair
pp. s1108–s1127 · DOI: 10.5530/ijper.58.4s.110 · Published 2024
Magnolia bark is an important food supplement. Magnolol (ML), 3,3′-Neoligna-8,8′-diene-4,4′- diol, is a bioactive phenolic molecule found in the Magnoliafamily. Advanced Drug Delivery Systems (DDSs) have been able to enh…
Review
Impact of Dietary Supplements in Alleviating Human Lifestyle and their Regulatory Aspects
Venkateswara Raju Kalidindi, Shankar Routhu, Dhamasri Gopisetty, Phanindra Varma Alluri, Lakshmi Prasanthi Nori
pp. s1128–s1144 · DOI: 10.5530/ijper.58.4s.112 · Published 2024
Dietary supplements generally items which have the goal of boosting the person's wellness and general well-being and are often ingested at mealtime or in scheduled times in order to improve a person's dietary routine. On…
Review
Critical Review of Risk Assessment Tools in Pharmaceutical Quality by Design
Palak Karia, Anita Ayre, Asrin Khan
pp. s1145–s1155 · DOI: 10.5530/ijper.58.4s.113 · Published 2024
Pharmaceutical Quality by Design is a systematic approach to product development that starts with specified objectives and emphasizes product knowledge, methodologies, and operational procedures. It is based on trustwort…
Review
Spray Dried Nanoparticle for Pulmonary Delivery: Current Developments and Future Perspectives
Yuvraj Sakharam Pawara, Hitendra Shaligram Mahajan
pp. s1156–s1168 · DOI: 10.5530/ijper.58.4s.114 · Published 2024
Aim: The study aims to comprehensively review advancements in spray-dried nanoparticles for pulmonary drug delivery. It focuses on understanding current techniques, nanoparticle types and applications. Additionally, it a…
Review
Immune Checkpoint Inhibitors for Cancer Therapy: Status and Future Directions
Md Shamsher Alam, Shenggang Wang, Asim Najmi
pp. s1169–s1184 · DOI: 10.5530/ijper.58.4s.115 · Published 2024
Among various treatment modalities available for the treatment of cancer, immunotherapy is one of the important strategies used for the management of different malignancies. Immune checkpoint inhibitors are used for the …
Review
Nanotechnology-Driven Approaches in Overcoming Drug Delivery Challenges for Neurodegenerative Diseases
Rajamanickam Palaniyappan, Saravanakumar Arthanari, Mohanraj Subramanian, Parthiban Periyasamy, Palanisamy Pethappachetty, Ragupathi Ganesan, Manivasakam Prakash, Anandharaj Govindaraj
pp. s1185–s1200 · DOI: 10.5530/ijper.58.4s.116 · Published 2024
The management of Neurodegenerative Diseases (NDs) is a substantial concern for healthcare systems at present. Alzheimer’s disease, frontotemporal dementia, Parkinson’s disease, prion disease, Huntington’s disease and Am…
Review
Question Paper Design in Line with Outcome-Based Education Policy
Parixit Bhandurge, Shailendra Sanjay Suryawanshi
pp. s1201–s1210 · DOI: 10.5530/ijper.58.4s.117 · Published 2024
Outcome-Based Education (OBE) is an educational framework that focuses on achieving specific, measurable outcomes in terms of student learning and performance. Unlike traditional education models that emphasize content d…

Original Article

Article
Enhanced Antifungal Efficacy of Transferosomal Gel Containing Clotrimazole and Miconazole Nitrate: A Novel Approach for Topical Treatment by QbD
Girish Meravanige, Madhu Bommanahalli Krishnegowda, Kumarswamy Kunigal Chandru, Prakash S Goudanavar, Suryawanshi Sopan Vishwambhar, Nimbagal Ragavendra Naveen, Afzal Haq Asif, Predeepkumar Narayanappa Shiroorkar, Nagaraja Sreeharsha, Ranjith Kumar Karnati
pp. s1211–s1223 · DOI: 10.5530/ijper.58.4s.118 · Published 2024
Aim: This study focuses on developing and evaluating a transferosomal gel containing clotrimazole and miconazole nitrate, antifungal medications used to treat fungal infections, including superficial tinea and nail infec…
Article
Establishment and Validation of LC-MS/MS Technique for Pafolacianine Quantification in Rat Plasma, with Application to Pharmacokinetic Assessment
Sandhya Pilli, Sri Nataraj Kalakonda, Vijayalakshmi Rajendran
pp. s1224–s1233 · DOI: 10.5530/ijper.58.4s.119 · Published 2024
Background: Establishing and validating a sensitive and accurate LC-MS method for quantifying pafolacianine in rat plasma was the primary objective of this study. Phenylalanine was used as the internal standard, and the …
Article
Evaluation of Cardiac Myosin Binding Protein-C3 (cMyBP-C3) as Potential Risk Factor of Acute Coronary Syndrome in Diabetic Patients
Wafaa Sh. Al-Zuhairi, Leila Sadeghi, Ekhlas Abdallah Hassan
pp. s1234–s1241 · DOI: 10.5530/ijper.58.4s.120 · Published 2024
Background: Recent years, the prevalence of Type 2 Diabetes Mellitus (T2DM) has increased annually. The major complication of T2DM is Cardiovascular Disease (CVD). Cardiovascular disease is the main cause of death in T2D…
Article
Effects of Foliar Application of Chitosan on Some Vegetative Growth and Biochemical Parameters of Strawberry Under Salt Stress
Beril Kocaman
pp. s1242–s1249 · DOI: 10.5530/ijper.58.4s.149 · Published 2024
Aim/Background: This research, which was carried out as a pot experiment in a plastic greenhouse to examine the effects of three different salt (NaCl) doses (Control, 30, 60 mmol/L) and three different chitosan doses (Co…
Article
Greenness and Whiteness Assessed Mathematically Filtered UV Spectroscopic Approaches for Quality Control of Amlodipine, Telmisartan and Metoprolol from Ternary Formulation
Mahesh Attimarad, Krishna Swaroop Duddi Sreehari, Bandar Aldhubiab
pp. s1250–s1261 · DOI: 10.5530/ijper.58.4s.148 · Published 2024
Background: Latest studies highlight the effectiveness of a new combination tablet that contains Amlodipine (AML), Telmisartan (TEL), and Metoprolol (MET) for the treatment of hypertension. The present work demonstrates …
Article
A Validated LC-MS/MS Method for Determination at Trace Level of Nitrosamine Impurities in Doxofylline API
Swetha Sri Remidicherla, Guntupalli Chakravarthi, Narender Malothu
pp. s1262–s1270 · DOI: 10.5530/ijper.58.4s.121 · Published 2024
Background: The FDA looked at popular amine-based API synthesis processes and found that these processes might additionally introduce nitrosamine-hazardous substances. The current method describes trace-level quantificat…
Article
An Albumin-Based Amygdalin-Glutaraldehyde Nanoparticle Induces Apoptosis in Oral Cancer KB Cells
Murugan Alwarkurichi Munusamy, Kalpana Sukumar, Muruganantham Bharathi, Abdullah A. Alarfaj, Samer Hasan Hussein-Al-Ali
pp. s1271–s1281 · DOI: 10.5530/ijper.58.4s.122 · Published 2024
Background: There is potential for nanotechnology to address the drawbacks associated with conventional cancer therapies. The current study was undertaken to formulate amygdalin-functionalized Albumin-Glutaraldehyde Nano…
Article
Pharmacokinetic Profile of Bioanalytical Method Development and Validation of Clarithromycin from Human Plasma by Using Liquid Chromatography Tandem Mass Spectrometer
Jayaprakash Jayavel, Umamaheshwari Duraisamy, Kumar Mohan
pp. s1282–s1288 · DOI: 10.5530/ijper.58.4s.123 · Published 2024
Aim: To develop and validate a sensitive and specific bioanalytical method for the quantification of clarithromycin in human plasma using Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS). Additionally, to charac…