Volume 11, Issue 4

Kakuli Chakraborty, Pratiti Ghosh

pp. 345–348 · DOI: 10.5530/ijpi.2021.4.61 · 2021

P-glycoprotein is an efflux transporter belonging to the ATP Binding Cassette (ABC) family of transporters and is encoded by Multidrug resistance (MDR1) gene. It is primarily involved in efflux of xenobiotics that permea…

Mausami Vaghela, Pankaj Kapupara

pp. 349–353 · DOI: 10.5530/ijpi.2021.4.62 · 2021

Regardless of a product’s country of registration, a current and updated pharmaceutical product dossier is mandatory. But any kind of post-approval change to pharmaceutical products requires prior permission or at least …

Suresh Babu Bastipati, Chepuri Kalyani, Chidepudi Devi Sri Lalitha Naga Tulasi, Lavudi Saida

pp. 354–357 · DOI: 10.5530/ijpi.2021.4.63 · 2021

Objectives: In the present study, the anticancer potential of the plant extracts of Elytraria acaulis L. (E. acaulis L.) were investigated on human breast cancer cells (MDAMB-231). Methods: Different organic solvent extr…

Swapnil Prakash Chaudhari, Dheeraj Tukaram Baviskar

pp. 358–361 · DOI: 10.5530/ijpi.2021.4.64 · 2021

Background:The aim of present study is to evaluate the anti-inflmmatory activity of Chlorella vulgaris in acute and chronic experimental inflammatory model. Plant extract was analyzed for photochemical screening of diffe…

Brindha Sundaramoorthy, Achintya Kumar Mandal, Vinayak Soman, Shree Devi Munusamy Sampangiramulu, Sunil Kumar Koppala Narayana, Shakila Ramachandran, Sathiyarajeswaran Parameswaran, Kiruthiga Ganesan

pp. 362–367 · DOI: 10.5530/ijpi.2021.4.65 · 2021

Introduction:Siddha being one of the ancient systems of medicine, has been counted on by most of the population during the outbreak of pandemics in recent times. The decoctions like nilavempu kutinir and kapacura kutinir…

Sumera Mehfooz, Abdul Wadud, Hamiduddin H, Rajeev Ranjan

pp. 368–373 · DOI: 10.5530/ijpi.2021.4.66 · 2021

Background:Kushta, a dosage form of Unani medicine is prepared by employing well-designed procedures. The correct procedure ensures the production of Kamil (perfect) Kushta considered as safe, while a deviation from the …

Megha Tukaram Salve, Shailaja Bhanudas Jadhav

pp. 374–378 · DOI: 10.5530/ijpi.2021.4.67 · 2021

Background: Diabetes is a long-term illness characterized by high blood sugar levels. It is estimated that by 2045, there will be nearly 693 million diabetic patients worldwide, with half of the population remaining undi…

Puteri Heryani Supriatna, Harmita Harmita, Yahdiana Harahap

pp. 379–383 · DOI: 10.5530/ijpi.2021.4.68 · 2021

Objectives: The δ15N, δ13C, and δ2 H profile of the ephedrine as a methamphetamine precursor is a fingerprint to describing its origin. The origin of the precursor is one of the supporting data in methamphetamine profili…

Ferdos Kord Mostafapour, Maryam Bazi, Shaziya Haseeb Siddiqui, Hossein Bagheri, Davoud Balarak

pp. 384–388 · DOI: 10.5530/ijpi.2021.4.69 · 2021

Background:Antibiotics have lasting effects on the environment. Among the properties of these substances are non-biodegradable, carcinogenic, high toxicity, and an increase in antibiotic-resistant bacteria. Therefore, th…

B Sreenatha Gupta, Madhusudhan Rao Vallabhaneni

pp. 389–394 · DOI: 10.5530/ijpi.2021.4.70 · 2021

Background:Electrochemistry was the foremost subdivision of the chemistry its interred correlated to the entire other chemistries. Primarily it can settle on the nature of compound reactions by physically depends on the …

Shaik Reehana, Kamepalli Sujana

pp. 395–402 · DOI: 10.5530/ijpi.2021.4.71 · 2021

Background:Palbociclib is anti-cancer drug which interacts with cyclindependent kinase. There are no methods repoRTed for the characterization of palbociclib together with degradation products (DPs). The main aim of the …

Hyma Ponnaganti, Ramesh Alluri, Jyothi Vemuri

pp. 403–407 · DOI: 10.5530/ijpi.2021.4.72

Background:Systems of floating drug delivery have a bulk density less than gastric fluids and thus it remains buoyant in the stomach without having any effect on gastric emptying rate for prolonged period of time. Rilpiv…

Ankita Tiwari, Sanjay K Jain

pp. 408–413 · DOI: 10.5530/ijpi.2021.4.73 · 2021

Background:Curcumin has been extensively employed in the treatment of several diseases in traditional medicine, including cancer.The main obstacles that avert its approval as a therapeutic moiety are its low aqueous solu…

Neelam Pawar, Anoop Parmar, Kavita Bahmani, DN Mishra, Renu Malik, Neha Minocha, Pawan Jalwal, Rahul Pawar

pp. 414–419 · DOI: 10.5530/ijpi.2021.4.74 · 2021

Background:The optimization study was conducted in an attempt to develop a non-pressurized topical spray of Lidocaine without propellant. Methods:Central composite design was selected to determine the best conditions for…

Archana Nerella, MV Nagabhushanam

pp. 420–425 · DOI: 10.5530/ijpi.2021.4.75 · 2021

Background: Owing to overcome the dissolution limited bioavailability of Meloxicam, the current research involves the development of Orodispersible films using Meloxicam by employing Quality by Design. Methods:In this wo…

Amar Prashad Chaudhary, Jeswin George, Kaveri Kadowade, Lubna Faiyza, Rabiya Anjum, Uma V M, Sharath K N

pp. 426–431 · DOI: 10.5530/ijpi.2021.4.76 · 2021

Background: This survey aims to determine medication compliance among hypertension patients and discover factors influencing medication compliance. Methods:This study incorporated a cross-sectional study design. The Hill…

Jisha Annie, RC Doijad, Emmanuel James

pp. 432–436 · DOI: 10.5530/ijpi.2021.4.77 · 2021

Background:To analyze the drug prescription pattern for secondary prevention of stroke, medication adherence, knowledge and awareness about the disease, direct medical cost involved in the treatment of stroke. Methods:A …

Swati Siddheshwar Londhe, Amol Arun Joshi, Geeta Narsingrao Sapkale, Mangesh Gautam Bhosale

pp. 437–440 · DOI: 10.5530/ijpi.2021.4.78 · 2021

Background:The skin is a very sensitive protective layer for the human body and is exposed to environmental pollution, so it is very important to protect the skin. Facial skin can be protected by using various cosmetics …

Rashmi Wadhwa, Pankaj Gupta

pp. 441–443 · DOI: 10.5530/ijpi.2021.4.79 · 2021

Background: The current study focuses in vitro anti-inflammatory and anti-proliferative evaluation of the alcoholic extract of euphorbia hirta roots. Anti-inflammatory potential was screened by incorporating inhibition o…