International Journal of Pharmaceutical Investigation
Volume 16, Issue 2
2026 · pp. 1–761 · 43 articles
- Volume
- 16
- Issue
- 2
- Published
- 2026
- Pages
- 1–761
- Articles
- 43
- Sections
- 3
- ISSN
- Print - 2230-973X, Online -2230-9713
- Journal
- IJPI
In this issue
21–40 of 43Review Article
- Review
Mary Brenda Ogwang, Deepak Kumar Jha, Sandipan Chatterjee
pp. 371–383 · DOI: 10.5530/ijpi.20260022 · 2026
Aim and Objectives This study aims to evaluate and analyze the concept of neuroprotection in Parkinson’s Disease (PD) by investigating the underlying mechanisms responsible for dopaminergic neuronal death. It explores ho…
- Review
Vaishnavi N. Thute, Sukeshini Lote
pp. 384–397 · DOI: 10.5530/ijpi.20260274 · 2026
The process of drug discovery is slowly entering the era of change, wherein more efficient and effective approaches to identify the potential therapeutic compounds are sought. This review article explores the future of d…
- Review
Arige Sirisha, Rama Rao Vadapalli, Penmatsa Srinidhi, Bathula Mahalakshmi, Muchakarla Sri Yagna, Kanuri Teja, T. Sowmya Sri
pp. 398–404 · DOI: 10.5530/ijpi.20260341 · 2026
Cancer is the most leading cause of the death. Only few treatment options are available for treating the cancer such as radiation therapy, chemotherapy, and surgery. These treatment options can either used as single or c…
- Review
Thalal Mohamed, Srimathi Mahadevan, Jayashri Vidya Prabhakaran, Sundari Venkatesan, Mohammed Fayaz, Vijayakumar Thangavel Mahalingam
pp. 405–413 · DOI: 10.5530/ijpi.20260349 · 2026
Tirzepatide is redefining the treatment landscape for metabolic and non-metabolic disorders. By uniquely harnessing two critical hormonal pathways, the review provides comprehensive insights into how Tirzepatide’s dual m…
- Review
Harshith Naganna, Kumble Prakash Rao Tejas Rao, Tejaswi Hiremarali Lokanathan, Mathada Vamadevaiah Ravishankar
pp. 414–424 · DOI: 10.5530/ijpi.20260360 · 2026
Plastic is found with its wide applications worldwide to fulfil our domestic and industrial needs. Its vast diversified usability and unscientific disposal patterns cause tireless accumulation of various forms of plastic…
- Review
Kirtimaya Mishra, Asra Jabeen, Swetha Vegesna, Gowri Sankar Chintapalli, Debasis Patra, Diptimayee Jena
pp. 425–430 · DOI: 10.5530/ijpi.20260373 · 2026
Mouth Dissolving Tablets (MDTs) are considered as a novel approach to improvize patient compliance and fast drug delivery. They constitute a significant improvement in pharmaceutical technology. The dissertation explores…
- Review
Niyati Shah, Ritu Sapra, Maitry Suthar, Piyushkumar Sadhu, Nisha Mandloi, Mamta Kumari, Chitrali Talele, Chintan Aundhia
pp. 431–441 · DOI: 10.5530/ijpi.20260010 · 2026
Breast cancer remains a significant global health challenge, necessitating innovative therapeutic approaches to improve patient outcomes. Drug delivery systems have emerged as promising tools to enhance the efficacy and …
- Review
Kalyani Andraskar, Krishna Raj, Abhay Tiwary, Poonam Lal
pp. 442–449 · DOI: 10.5530/ijpi.20260430 · 2026
Nanoparticles of Titanium Dioxide (TiO₂) have also become an essential element of nanomedicine because of their multifunctionality and wide use in medicine. This review compiles current advances in the synthesis, functio…
- Review
Mayur Rajeshwar Dandekar, Isha anil Mirzapure, Yash Manoj Salve, Deepak Khobragade
pp. 450–461 · DOI: 10.5530/ijpi.20260432 · 2026
Real-time release Testing is now considered one of the breakthroughs in pharmaceutical quality control, replacing the old batch-testing paradigms with a modern, real-time, more efficient, data-driven approach. RTRT combi…
- Review
Mayur Dandekar, Deepak khobragade, Yash Salve, Sakshi Mandhane, Isha Mirzapure
pp. 462–469 · DOI: 10.5530/ijpi.20260480 · 2026
The importance of GMP audits in ensuring the quality, safety, and efficacy of pharmaceuticals is unmistakable. These audits are systematic appraisals of facilities, processes, personnel, documentation, and quality manage…
- Review
Shweta Bhandari, Rahul Trivedi, Rajesh Hadia, Ajay kumar Saini, Vishal Garg, Ram Singh
pp. 470–475 · DOI: 10.5530/ijpi.20260588 · 2026
Vaccines have saved millions of lives and reduced the spread of infectious diseases, thereby transforming global health. This comprehensive overview traces the historical evolution of vaccines-from ancient inoculation pr…
- Review
Mohammed Tarique, Ziaullah Sain, Yusuf Ahmad
pp. 476–489 · DOI: 10.5530/ijpi.20260154 · 2026
Malaria, which is caused by Plasmodium parasites, remains a major international health issue, especially in developing countries. The problem of drug resistance has become a major concern, especially with respect to arte…
- Review
Rohit Bairagi, Ruchi Suryawanshi, Suankit Harane, Milind Umekar, Vinita Kale
pp. 490–499 · DOI: 10.5530/ijpi.20260578 · 2026
Juvenile Animal toxicity Studies (JAS) are conducted to evaluate potential safety risks, particularly those affecting postnatal growth and development, that may not be detectable through standard toxicity studies or pedi…
- Review
M Varsha, Sarumathy Sundararajan
pp. 500–506 · DOI: 10.5530/ijpi.20260065 · 2026
L-Carnitine, a naturally occurring quaternary amine, plays a crucial role in mitochondrial fatty acid transport and energy metabolism. This narrative review explores the pharmacological significance of L-Carnitine in rep…
- Review
Navigating the Landscape of OTC Drug Utilization and Regulatory Challenges in India: Insights Review
Blessy K George, Jaidev Kumar, Sunil Kumar, Balakeshaw Ramaiah
pp. 507–516 · DOI: 10.5530/ijpi.20260514 · 2026
This review article on utilization and regulations of OTC drugs aims to highlight the significance of establishing legal policies on "OTC medicines" in India by outlining the potentially harmful effects of these medicati…
- Review
Yogita Shinde, Tanishka Prakash Sharma, Archana Shaha, Rakesh Chaudhari, Rashmi Rajeghorpade, Dipali Talele, Chitrali Talele
pp. 517–522 · DOI: 10.5530/ijpi.20260539 · 2026
Messenger RNA (mRNA) therapies are a groundbreaking treatment for various conditions, including infectious diseases, cancer, and genetic disorders. This review examines the processing of mRNA therapeutics in the body, fo…
- Review
Qamre Alam, Reem Saeed Alazragi, Alaa Al-Kathiri, Alrayan Abass Albaz, Jawaher Mohammad Alshehri, Fatimah Ali Alsaffar, Dalia Alammari, Saleh Alqahtani
pp. 523–535 · DOI: 10.5530/ijpi.20260153 · 2026
This review thoroughly examines Breast Cancer Stem Cells (BCSCs) discussing their involvement, in tumor advancement and spread and their resistance to treatment while also discussing methods for targeting them for elimin…
- Review
Santosh Kumar Dash, Ashutosh Padhan, Abdul Sayeed Khan, Tusara Kanta Behera, Sachhidananda Mohapatra, Sulagna Parta, Ranjan Kumar Sahoo
pp. 536–540 · DOI: 10.5530/ijpi.20260109 · 2026
Cancer remains a leading cause of global mortality. Conventional treatments such as chemotherapy, radiation, and surgery often lead to severe side effects and limited effectiveness. Nanoparticulate Drug Delivery Systems …
- Review
Arya Deshmukh, Mujibullah Sheikh, Akanksha Dange
pp. 541–560 · DOI: 10.5530/ijpi.20260081 · 2026
Autism Spectrum Disorder (ASD) is a heterogeneous neurodevelopmental condition characterized by deficits in social interaction and communication alongside repetitive behaviors and restricted interests. Despite substantia…
- Review
Nandula Lavanya, Rashmi Nelligare Gopalakrishna
pp. 561–568 · DOI: 10.5530/ijpi.20260469 · 2026
Advancements in drug development emphasize enhancing efficacy, reducing side effects, and tailoring treatments to individual patient needs. Conventional antidepressant therapies often face limitations such as delayed ons…