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International Journal of Pharmaceutical InvestigationNOW IN
International Journal of Pharmaceutical Investigation volume 13, issue 2 cover
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Cover: International Journal of Pharmaceutical Investigation

International Journal of Pharmaceutical Investigation

Volume 13, Issue 2

· pp. 206–366 · 18 articles

Volume
13
Issue
2
Published
Pages
206–366
Articles
18
Sections
2
ISSN
Print - 2230-973X, Online -2230-9713
Journal
IJPI
Review ArticleOriginal Article

In this issue

Review Article

  1. Review

    Green Indicators-An Ecofriendly Endpoint

    Sri Nataraj Kalakonda, Srinivasa Rao Atla, Roja Naveena Puvvada, Prapul Kumar Nalli, Ijaz Sheik, Rajendra Prasad VVS

    pp. 206–214 · DOI: 10.5530/ijpi.13.2.028 · Published

    Although acid-base titrations can be done using numerous indicators which are either synthetic or semi-synthetic, the investigation was started for natural compounds as the former ones result in polluting the habitat des…

  2. Review

    A Detailed Insight of Monkey Pox Virus Infection in Adolescent

    Ankita Wal, Garima Vishnoi, Divyanshi Gupta, Parul Srivastava, Pranay Wal, Awani K Rai

    pp. 215–223 · DOI: 10.5530/ijpi.13.2.029 · Published

    Background: Smallpox-like symptoms are seen in the viral zoonotic illness known as monkeypox. In the current outbreaks being reported, the World Health Organization (WHO) claims that this is the first instance of chains …

  3. Review

    An Overview of Corrective Action and Preventive Action

    Shantanu S Thakre, Rohit S Gahilod, MP Venkatesh

    pp. 224–230 · DOI: 10.5530/ijpi.13.2.030 · Published

    Corrective and Preventive Actions (CAPA) are crucial for enhancing and raising the quality of the finished good or service. It is essential to every industry's ongoing development. In any pharmaceutical or medical device…

Original Article

  1. Article

    Development of a Floating Drug Delivery System for Prolonged Release of Metronidazole in the Stomach for Gastrointestinal Infection

    Aanantha Kumaran, Sruthi Laakshmi M, Gouranga Dutta, Abimanyu Sugumaran, Damodharan Narayanasamy

    pp. 231–237 · DOI: 10.5530/ijpi.13.2.031 · Published

    Introduction:Gastroretentive Drug Delivery System like floating tablets out performs traditional dosing forms. When compared to conventional tablets, floating tablets have higher bioavailability, higher drug concentratio…

  2. Article

    Evaluation of Sono-photocatalytic Removal of Ciprofloxacin Antibiotic Using Magnesium Oxide Nanoparticles from Aqueous Solutions

    Ferdos Kord Mostafapour, Mohammadreza Radmehr, Shaziya Haseeb Siddiqui, Davoud Balarak

    pp. 238–242 · DOI: 10.5530/ijpi.13.2.032 · Published

    Objectives: The entry of antibiotics into surface and groundwater will cause problems in the environment. This study aimed to investigate the removal efficiency of ciprofloxacin (CFX) from aqueous solutions using the son…

  3. Article

    Co-crystals: A Novel Approach to Improve the Solubility of Apixaban

    Amit V Asati, Kishor S Salunkhe, Rudra Pratap Singh Rajput, Sonali R Chintamani, Akshay U Khairnar, Nilesh S Patil, Ravindra N Chintamani

    pp. 243–247 · DOI: 10.5530/ijpi.13.2.033 · Published

    Objectives:The current study work was aimed to improve the solubility of Apixaban by forming co-crystals. Materials and Methods:Two solvents mainly Dimethyl Sulphoxide (DMSO) and 2,2,2-trifluoroethanol were tried during …

  4. Article

    Evaluation of Anthelmintic Activity and GC-MS Characterization of Urochloa distachya (L.)

    Smrutiranjan Dash, Janki Bohidar, Chandan Das, Arnabaditya Mohanty, Ashutosh Meher, Raghunandan Hota

    pp. 248–254 · DOI: 10.5530/ijpi.13.2.034 · Published

    Background:The helminthiasis parasitic worm present in the gastrointestinal tract of the animal cause infection and physiological damage. This occurs due to poor sanitation, impecunious personal hygiene, low socioeconomi…

  5. Article

    In-vitro Antioxidant and Antitumor Activity of Dihydropyrimidine-2(1-H)-thione Derivatives with Carbazole Moiety

    Purushotham KN, Bevinahalli Ramesh, Thoppalada Yunus Pasha

    pp. 255–260 · DOI: 10.5530/ijpi.13.2.035 · Published

    Aim:Prepared a series of molecules called Dihydropyrimidine- 2( -H)-thione of carbazole to evaluate antioxidant and antitumor activity. Materials and Methods: Compounds from DTP- to DTP- were prepared and subjected for S…

  6. Article

    Stability Indicating HPLC Method for Simultaneous Assessment of Clopidogrel Bisulfate and Aspirin: Development and Validation

    Shahnaz Usman, Muhammad Akram, Fasiha Shah, KVRNS Ramesh, Quamrul Islam

    pp. 270–278 · DOI: 10.5530/ijpi.13.2.037 · Published

    Objectives:The efforts were made to develop a HPLC analytical method for the simultaneous quantitative estimation of aspirin and clopidogrel and aim to identify and estimate the degradation of the drugs under the various…

  7. Article

    Stability Indicating RP-HPLC Method for Quantitative Estimation of Levetiracetam and its Impurities in Pharmaceutical Dosage Form

    P Venkateswara Rao, V Anuradha, D Ramachandran, CV Nageswara Rao

    pp. 279–289 · DOI: 10.5530/ijpi.13.2.038 · Published

    Objectives: A simple, precise, accurate, robust and selective stability-indicating reverse phase high performance liquid chromatographic method for the separation and quantification of Levetiracetam and its impurities in…

  8. Article

    A Green Eco-friendly Analytical Method Development, Validation, and Stress Degradation Studies of Favipiravir in Bulk and Different Tablet Dosages Form by UV-spectro- photometric and RP-HPLC Methods with their Comparison by Using ANOVA and in-vitro Dissolution Studies

    Subhadip Chakraborty, Sumanta Mondal

    pp. 290–305 · DOI: 10.5530/ijpi.13.2.039 · Published

    Favipiravir is an antiviral drug with significant and widespread antiviral action. Favipiravir was crucial in the contest against the COVID-19 pandemic because of how well it treated the SARS-CoV-2 virus. It is well know…

  9. Article

    A Stability Indicating RP-HPLC Method for Simultaneous Estimation of Acebrophylline, Montelukast, and Fexofenadine in Bulk and Pharmaceutical Dosage Forms

    Sreedevi Adikay, Mounika Bhavanasi, Sai Sruthi Kaveripakam

    pp. 306–312 · DOI: 10.5530/ijpi.13.2.040 · Published

    Introduction: The goal of the current work is to create an RP-HPLC method for the quantitative analysis of Acebrophylline, Montelukast, and Fexofenadine in Pharmaceutical dosage form. Materials and Methods: Chromatograph…

  10. Article

    Synthesis, Characterization, RP-HPLC Method Development and Validation for Qualitative Estimation of (4Z) 3 Methyl 1 (4 Nitrobenzoyl) 1H Pyrazole 4,5 Dione 4[(4fluorophenyl) Hydrazone]

    Harsha Ashtekar, Natasha Aggarwal, Chaitra Raviraj, Gupta Dheeraj Rajesh, Nimmy Varghese

    pp. 313–320 · DOI: 10.5530/ijpi.13.2.041 · Published

    Aim: A new simple, accurate, precise, Reverse Phase High-performance Liquid Chromatography method was developed and validated for the estimation of newly synthesized (4Z) 3 methyl 1 (4 nitrobenzoyl) 1H pyrazole 4,5 dione…

  11. Article

    Fluorescence Emission and Molecular Docking Studies Identified Novobiocin as a Potent Inhibitor of the Japanese Encephalitis Virus (JEV) Envelope Protein

    Afaf S Alwabli

    pp. 321–328 · DOI: 10.5530/ijpi.13.2.042 · Published

    Introduction: The Japanese Encephalitis Virus (JEV) causes the acute inflammatory disease of the central nervous system known as Japanese encephalitis. JEV is a RNA virus (+strand) that is tiny, enclosed, and from the fa…

  12. Article

    A Pilot Study on Medication Adherence, Patient Satisfaction, KAP and Quality of Life of Hypertensive Patients

    Dilipkrishnan K, Gopalakrishnan G

    pp. 329–334 · DOI: 10.5530/ijpi.13.2.043 · Published

    Aim:The present study was designed as a pilot study to assess the prevalence and reasons for occurrence of hypertension and identify the various treatment options prescribed and to determine the patients’ awareness and a…

  13. Article

    Evaluation of Knowledge, Attitude and Practice towards Hypothyroidism among Population in Moradabad District: A Pilot Study

    Rahul Arora, Piyush Mittal, Anurag Verma, Jyoti Trivedi

    pp. 335–343 · DOI: 10.5530/ijpi.13.2.044 · Published

    Introduction:Thyroid problems are thought to be a widespread health problem in India, as they are across the world. However, there is a lack of data on these patients' knowledge, attitude, and practices (KAP). Objectives…

  14. Article

    Prevalence of Depression and Anxiety among General Population during COVID-19 Second Wave in Saudi Arabia

    Ahlam Furayhan Althobaiti, Shuruq Hamdan Alshalawi, Atheer Atallah Alqurashi, Waad Faris Altowairqi, Hajer Mubark Alsulami, Shaheen Sultana

    pp. 344–358 · DOI: 10.5530/ijpi.13.2.045 · Published

    Introduction:Coronavirus 22 9 (COVID- 9) pandemic had serious impact on people’s mental health in the 2 st century. Mental disorders have influenced economically on the society and have a dramatic effect on families too.…

  15. Article

    The Evaluation and Effectiveness of Regional Language Patient Information Leaflets for Persons with Chronic Kidney Disease

    Ruhul Amin, Biplab Kumar Dey, Faruk Alam

    pp. 359–366 · DOI: 10.5530/ijpi.13.2.046 · Published

    Objectives:The objective of this study was to develop Chronic Kidney Disease Patient Information Leaflets (CKD-PILs) to test their understandability and assess their usefulness. Materials and Methods:Prospective observat…