Volume 10, Issue 1

Subramani Parasuraman, Krishnamoorthy Venkates Kumar

pp. 1–2 · DOI: 10.5530/jyp.2018.10.1 · 2018

Stability is one of the key determinant in assessing the quality, safety and efficacy of Active Pharmaceutical Ingredient (API) or Finished Pharma ceutical Product (FPP). Stability issues in a pharmaceutical products cou…

Andika a, Linda Erlina, Azminah a, Arry Yanuar

pp. 3–6 · DOI: 10.5530/jyp.2018.10.2 · 2018

Objective: Sirtuins are protein deacetylases regulating cellular metabolism, lifespan, stress responses, and linked with diseases pathogenesis such as cancer and neurodegenerative diseases. SIRT1, one of human seven sirt…

Linda Erlina, Andika a, Azminah a, Arry Yanuar

pp. 7–11 · DOI: 10.5530/jyp.2018.10.3 · 2018

Objective: Nowadays, many researchers focused on finding and developing the new inhibitor of HDAC4 and HDAC7 using in silico tools such as docking, pharmacophore approaches, and molecular dynamics simulation. The aim of …

Alvan F. Shalas, Siswandono s, Marcellino Rudyanto

pp. 12–15 · DOI: 10.5530/jyp.2018.10.4 · 2018

Objective: The study aimed to synthesize four analogs of 1-allyl-3-benzoylthiourea (R= H; 2-Cl; 3-Cl; and 4-Cl), and evaluate their pain inhibition activities. Method: The chemical structure was drawn assisted by Chem- D…

Krishna kumar K, Dinesh kumar B, Rini Ramesh Punathil

pp. 16–19 · DOI: 10.5530/jyp.2018.10.5 · 2018

Objective: To synthesize silver nanoparticles from leaves extract ofHydnocarpus Pentandra (H. Pentandra) and test the anti-cancer activity of synthesized silver nanoparticles against breast cancer cell line (MCF-7 cells)…

Susana Elya Sudradjat, Kris Herawan Timotius, Abdul Mun’im, Effionora Anwar

pp. 20–23 · DOI: 10.5530/jyp.2018.10.6 · 2018

Background: Nutmeg oil is used in Asia as a traditional medicine for a stomach cramps, diarrhea, and insomnia. It’s quality need to be improved by increasing myristicin content. Objectives: This study aimed to increase t…

Captain Khushali, Kale Rupali, Shirolkar Satish

pp. 24–26 · DOI: 10.5530/jyp.2018.10.7 · 2018

Objective: To formulate and optimise stable caries removing gel using naturally extracted papain and clove, for non– invasive chemo–mechanical removal of dental caries. Methodology: Gel formulation was prepared using nat…

Silvia Surini, Sarah, Joshita Djajadisastra

pp. 27–31 · DOI: silvia.surini@ui.ac.id · 2018

Objective: Asiaticoside from gotu kola leaves extract (Centella asiatica L. Urban) could be used for anti-aging cosmetics. Nevertheless, its skin penetration is difficult, since it has a high molecular weight. Transferso…

Nagalakshmi Sethuraman, Anbarasan Balu, Ramesh Selvaraj, Thanka Johnson, Shanmuganathan Seetharaman

pp. 32–36 · DOI: 10.5530/jyp.2018.10.9 · 2018

Objective: The goal of the study was to formulate and characterized the pH stimuli sensitive based hydrogels for the effective treatment of infected eye. Method: Simple method of preparation was adapted. Result: The opti…

Siti Nashihah, Abdul Mun’im, Sutriyo s, Fadlina Chany Saputri

pp. 37–40 · DOI: 10.5530/jyp.2018.10.10 · 2018

Objective: This study was conducted to evaluate the encapsulated Rice Bran Oil with sodium alginate to improve stability and reduce rancidity by using ionic gelation method. Method: Response Surface Methodology design we…

Silvia Surini, Khansa Nursatyani, Delly Ramadon

pp. 41–47 · DOI: 10.5530/jyp.2018.10.11 · 2018

Objective: Grape seed oil (GSE) from Vitis vinifera L. has a high linoleic acid content, which plays a role in the skin moisturizing. However, linoleic acid is a liquid form and easily oxidized. The aims of this research…

Yahdiana Harahap, Fauzan Alkindy, Ghina Ashiila, Rahmayanti r

pp. 48–51 · DOI: 10.5530/jyp.2018.10.12 · 2018

Objective: This research aimed to determine rifampicin in dried blood spot of tuberculosis patients using cilostazol as internal standard by high performance liquid chromatography for supporting therapeutic drug monitori…

CN Prathyusha Naik, KB Chandra Sekhar

pp. 52–56 · DOI: 10.5530/jyp.2018.10.13 · 2018

Objective: A reliable RP-HPLC SIAM (stability indicating assay method) was developed for the approximation of armodafinil in presence of its degradation product in pharmaceutical dosage forms. Materials and Methods: Mobi…

Syed Kashif, Rema Razdan, Rohitash Jamwal, Sumanta Kumar Goswami

pp. 57–61 · DOI: 10.5530/jyp.2018.10.14 · 2018

Objective: A majority of the diabetic patients experience sexual dysfunction. The objective of the study was to investigate the effect of allantoin on sexual dysfunction in diabetic rats. Methods: Streptozotocin-induced …

Angeline Julius, Waheeta Hopper

pp. 62–65 · DOI: 10.5530/jyp.2018.10.15 · 2018

Background: Diabetes and cancer have been the leading cause of mortality all over the world. Studies on association between diabetes and cancers over a decade indicate a positive relationship between them. Epidemiologic …

Jas Min Oh, Long Chiau Ming, Faizah Safina Bakrin, Bey Hing Goh, Learn Han Lee, Tahir Mehmood Khan

pp. 66–73 · DOI: 10.5530/jyp.2018.10.16 · 2018

Background: This study explored the knowledge of attitudes to and perception of consumption of antibiotics, and understanding of antibiotic resistance among students and general population across South and East Asia regi…

Kamath Priyanka, Chowta Mukta Nithyananda, Ramapuram John Thomas, Shenoy Ashok Kudgi, Hadigal Sanjay

pp. 74–77 · DOI: 10.5530/jyp.2018.10.17 · 2018

Background and Objective: To compare the immunological response to antiretroviral therapy between genders and to identify other factors that could affect the immunological response. Methods: This was a prospective, obser…

Subratha C, Naveen Kumar, Bryal D’ Souza, Arun Mavaji, Rajesh Kamath

pp. 78–81 · DOI: 10.5530/jyp.2018.10.18 · 2018

Aim: To apply matrix analysis using the principles of Always Better Control(ABC), Vital, Essential and Desirable (VED) analysis and inventory index for inventory control and to identify the drugs that require management …

Chandresh B. Dumatar, Sandip S. Jadav, Aashutosh J. Patel

pp. 82–85 · DOI: 10.5530/jyp.2018.10.19 · 2018

Objective: To evaluate the usage pattern of antithrombotic in patients suffering from deep vein thrombosis (DVT) in a tertiary care teaching hospital. Methods: It was an observational, prospective and single centre study…

Dilip Chandrasekhar, Aswathi Shaji, Ardra Mariet Jose, Asifa Abdul Kareem, Levin Thomas

pp. 86–90 · DOI: 10.5530/jyp.2018.10.20 · 2018

Background: Due to low literacy rates and poor economic status rural women are either completely or partially unaware about modern Family Planning techniques and proper scientific maternal care and child care. “SAHELI”- …