Volume 10, Issue 2

Ravichandran V

pp. 131 · DOI: 10.5530/jyp.2018.10.30 · 2018

Chemistry is a distinguished part of our daily lives. Food and drink has been made safe to consume, the development of cosmetics allowed us to beautify and venerate our appearances and the whole area of pharma ceuticals …

Abhishek Sunil Dhoot, Anup Naha, Juhi Priya, Neha Xalxo

pp. 132–137 · DOI: 10.5530/jyp.2018.10.31 · 2018

A phase is a physically discrete and chemically homogeneous portion of a system, separated by boundaries from other portions of the system. The phase rule given by J.W Gibbs in 1874 is applied to define a system composed…

Kavitha Muthu, Vedam Vaishnavi, Ganapathy Sivadas

pp. 138–143 · DOI: 10.5530/jyp.2018.10.32 · 2018

Oral Cancer (Oral Squamous Cell Carcinoma; OSCC) contributes to one of the important causes of mortality in human beings. These impending malignancies however may present clinically with warning signs and symptoms which …

Suelen Carneiro de Medeiros, José Edvar Monteiro-Júnior, Gleilton Weyne Passos Sales, Thalles Barbosa Grangeiro, Nádia Accioly Pinto Nogueira

pp. 144–148 · DOI: 10.5530/jyp.2018.10.33 · 2018

Chitinases are hydrolases that catalyze the cleavage of the β-1,4-Oglycosidic linkages in chitin, a polysaccharide abundantly found in nature. Chitin is an important structural component of the cell wall of most fungi an…

Aryendu Kumar Saini, Pranay Wal, Manisha Verma, Suresh Chandra, Anurag Singh, Sanjeev Yadav, Himanshu Bansode, Kumar Nischaya, Nikita Saraswat

pp. 149–154 · DOI: 10.5530/jyp.2018.10.34 · 2018

Nebivolol is a third generation beta-blocker that possesses the highest selectivity for beta-1 receptors than beta-2 receptors than any other beta blocker in its class. Long-term therapy of nebivolol, in clinical trials,…

Pragati Srivastava, Rashmi Rao R, Preethi J Shenoy, Poornima Ajay Manjrekar, S Teerthanath, Bhuvaneshwari S

pp. 155–158 · DOI: 10.5530/jyp.2018.10.35 · 2018

Background: Antioxidant rich herbs possess significant activity against various disease conditions induced by oxidative stress. Anethum graveolens is a rich source of bioactive compounds that possess varying pharmacologi…

Welligton Luciano Braguini, Natalia Valendolf Pires, Bruno Bianchin Alves

pp. 159 · DOI: 10.5530/jyp.2018.10.36 · 2018

Objective: The aim of the study was evaluate the tannin content, antioxidant activity and the lethality of unripe fruits extract of Solanum viarum Dunal (Solanaceae) against brine shrimps. Methods: The tested samples for…

Leandro Maciel Uchoa Gadelha, Lídia Audrey Rocha Valadas, Nicole de Mello Fiallos, Sônia Luque Peralta, Keniesd Sampaio Mendonça, Mara Assef Leitão Lotif, Gilvan Lima Bezerra, Márcio Glauber Lopes de Aguiar, Érika Sabóia Guerra Diógenes, Edilson Martins Rodrigues Neto, George Otávio Asevedo, Ana Cristina de Mello Fiallos

pp. 164–168 · DOI: 10.5530/jyp.2018.10.37 · 2018

Objective: This research analyzed in vitro the antifungal activity of the solution composed by grapes seed extract Vitis vinifera (Doctor’s A-Z®) against Candida albicans (ATCC 20231) species aiming to determine the mini…

Alvi Kusuma Wardani, Abdul Mun’im, Arry Yanuar

pp. 169–172 · DOI: 10.5530/jyp.2018.10.38 · 2018

Objective: This research was conducted to screen inhibition of HIV-1 reverse transcriptase activity of selected Indonesia medicinal plants and to isolate HIV-1 reverse transcriptase inhibitor from Erythrina variegata lea…

Chella Perumal Palanisamy, Anofi Omotayo Tom Ashafa

pp. 173–177 · DOI: 10.5530/jyp.2018.10.39 · 2018

Objectives: To evaluate the potential inhibitors aginst CXCR4 from hexane extract of Euclea crispa (E. crispa) leaves. Methods: The natural compounds were identified and charecterized through GC-MS analysis. Molecular do…

Rahma Muhammad Adamu, B. K. Malik

pp. 178–182 · DOI: 10.5530/jyp.2018.10.40 · 2018

Objective: To model a 3D-structure of Thymic Stromal Lymphopoietin (TSLP) and docking of small molecules for development of novel natural anti-allergic drug. Method: Crystal structure of the Mus musculus cytokine recepto…

Niken Indriyanti, Joewono Soeroso, Junaidi Khotib

pp. 183–186 · DOI: 10.5530/jyp.2018.10.41 · 2018

Background: Quercetin-3-O-rhamnoside (QUE) has anti-inflammatory and anti-oxidative effects which probably beneficially used in lupus. Objective: This research was focused on analyzing the effects of QUE on FOXP3 modulat…

Maximus M Taek, Bambang Prajogo EW, Mangestuti Agil

pp. 187–192 · DOI: 10.5530/jyp.2018.10.42 · 2018

Objective: This study aims to document ethnomedicinal plants used in the traditional treatment of malaria in some areas of Malaka District in West Timor, Indonesia. Methods: Semi-structured questionnaire interviews and f…

Pozdnyakov DI, Voronkov AV, Zolotych DS, Arlt AV

pp. 193–196 · DOI: 10.5530/jyp.2018.10.43 · 2018

Objective: To assess the effect of 4-hydroxy-3,5-di-tret-butyl cinnamic acid on the state of endothelial function under conditions of experimental cerebral ischemia. Materials and Methods: Antioxidant properties of 4-hyd…

Raja D, Deepthi Merin Raju, Indu TH, Sruthy KV, Jayakumar C, Ponnusankar S

pp. 197–201 · DOI: 10.5530/jyp.2018.10.44 · 2018

Introduction: Diabetes mellitus (DM) is a predominant source of morbidity in India. The incidence of depression is found to be increased among type 2 DM patients that makes the glycemic control as an exhaustive task and …

Manoj K Mudigubba, Yogananda Rajashekarachari, Saurabh Dahiya

pp. 202–207 · DOI: 10.5530/jyp.2018.10.45 · 2018

Objectives: To study the incidence and to evaluate the risk factors of suspected adverse drug reactions developed in the hospitalized patients of various departments and to assess the causality and severity of adverse dr…

Dilip Chandrasekhar, VM Ganesan, Sreelekha Sreekumar, Anuja Pradeep, Asha Susan Geoji, Athira Elezabath George, Athira V

pp. 208–212 · DOI: 10.5530/jyp.2018.10.46 · 2018

Aim: The study aims to evaluate the medication adherence behavior of individuals by using validated questionnaire and to enhance the adherence by using various cost effective interventional methods which likely have a gr…

Shraddha Milind Pore, Shreyas Ramchandra Burute, Amar Dinkar Shinde, Sunita Jaiprakash Ramanand

pp. 213–217 · DOI: 10.5530/jyp.2018.10.47 · 2018

Objective: The present study was undertaken to evaluate pattern, commonly implicated drugs, causality and severity of adverse drug reactions (ADRs) reported with antimicrobial drugs. Methodology: Antimicrobial drug relat…

Anmar Al-Taie, Aygül Koseoğlu

pp. 218–221 · DOI: 10.5530/jyp.2018.10.48 · 2018

Background: Port-A catheter is an implanted device used for frequent chemotherapy administration. It is not complications free and often requires an additional intervention for the assessment of possible complications an…

Bangunawati Rahajeng, Zullies Ikawati, Tri Murti Andayani, Iwan Dwiprahasto

pp. 222–225 · DOI: 10.5530/jyp.2018.10.49 · 2018

Objective: Pregabalin is an off-label drug used to reduce central neuropathy pain that often accompanies and affects the quality of life in central poststroke pain (CPSP). This study was conducted to determine the effect…