Volume 9, Issue 1

Chidambaram Ramasamy, Subrmani Parusuraman

pp. 1–2 · DOI: 10.5530/jyp.2017.9.1

Sleeping well is a fundamental right to any individual to maintain good physical and mental health. If that is so, should we mind when a patient dozes off in the medical units or dental reception? In layman’s terms in ad…

Sharanya Sankaran Kartha, Girish Pai Kulyadi, Krishnamurthy Bhat, Muddukrishna Badamane Sathyanarayana

pp. 3–7 · DOI: 10.5530/jyp.2017.9.2

Initially drugs are available for consumption to the public only after con sulting with a healthcare professional and obtaining a prescription for the same. However, to enhance consumer access to a safe and effective dru…

Rajeev Arunachalam, Vini Rajeev, Vaishnavi Vedam, Sivadas Ganapathy, Jawahar Dhanavel

pp. 8–13 · DOI: 10.5530/jyp.2017.9.3

Periodontal disease is an immuno-inflammatory condition involving the tissues that surround and support the teeth. Till date back bone of periodontal treatment is still mechanical removal of plaque and calculus deposits …

Sivadas Ganapathy, Vaishnavi Vedam, Vini Rajeev, Rajeev Arunachalam

pp. 14–22 · DOI: 10.5530/jyp.2017.9.4

Autoimmune disorders are formed in the body as an outcome of in appropriate immune response against its own tissues. Failure of this immune system to recognize the body’s normal constituents as “self” will result in infl…

M.A Hashem, Moinul Abedin Shuvo, Arifuzzaman a

pp. 23–30 · DOI: 10.5530/jyp.2017.9.5

Background:Zika virus is a flare-up mosquito-borne virus that manifests itself in sporadic human infections with Zika fever. It has a serious affect in pregnant women. Mother transmits Zika virus infection to her infant …

Rajavel Varatharajan, Lee Hui Jun, Tan Zhi Kai, Lim Wai Jian, James Anburaj, Venugopal Vijayan

pp. 31–35 · DOI: 10.5530/jyp.2017.9.6

Background:Gentamicin is an antibiotic that exhibits a broad spectrum of activity against microorganisms. Now a days uses of gentamicin are limited due to it potentially induces nephrotoxicity by selective accumulation o…

HimaVyshnavi A M, Lakshmi Anand C, Deepak O M, P K Krishnan Namboori

pp. 36–39 · DOI: 10.5530/jyp.2017.9.7

Background:The population-wise variation in proneness of Colorectal Cancer (CRC) has been studied in the manuscript. A population wise analysis of responsiveness towards colorectal cancer is carried out with genetic, epi…

Ghasak Ghazi Faisal, Mainul Haque, Ghazi Faisal Najmuldeen, Basma Ezzat Al-Ahmad, Ali Sabri Radeef, Ahmed Ghazi Alattraqchi

pp. 40–42 · DOI: 10.5530/jyp.2017.9.8

Objectives: Eurycoma longifolia jack root extract has been known for its aphrodisiac and anabolic properties. Our study aimed at investigating the effects of this extract on the serum leptin in relation to the well-known…

Saeedeh Shaker, Mohammad Hossein Morowvat, Younes Ghasemi

pp. 43–46 · DOI: 10.5530/jyp.2017.9.9

Objective:Microalgal pharmaceutical biotechnology is mainly dependent on the biomass yield and also the final concentration of the obtained lipids. β-carotene is one of the most precious nutraceuticals, of both preventiv…

Siva Prasada Reddy Maddirala Venkata, Peter Kielgast, Ubaidulla Udhumansha, Marja Airaksinen

pp. 47–54 · DOI: 10.5530/jyp.2017.9.10

Background:Community pharmacists could play more potential role when finding ways to allocate effectively limited healthcare resources in primary care in many developing countries, including India. Pharmacists could part…

M Kalaivani, Shruti Rastogi, V Kalaiselvan, G. N. Singh

pp. 55–59 · DOI: 10.5530/jyp.2017.9.11

Background: Safety of vaccines is more critical because they are used for immunization in children and Hepatitis-B vaccination is included in national immunization schedule for neonates and infants in India. The National…

Akanksha Suman, Devesh. D. Gosavi

pp. 60–64 · DOI: 10.5530/jyp.2017.9.12

Objective: To assess the prescription pattern & Adverse Drug Reaction (ADR)) profile of Antiepileptic drug (AEDs) therapy in children of rural population. Materials and Methods: This prospective open label, observational…

Prabhu Varsha A, Awasthi Shivanshu, Shanavas Rithu, Kunhikatta Vijayanarayana, Thunga Girish, Nair Sreedharan, Acharya Raviraja

pp. 65–68 · DOI: 10.5530/jyp.2017.9.13

Background: Deficits in the treatment options makes Acute Respiratory Distress Syndrome (ARDS) management more challenging. With Involvement of inflammatory pathways, corticosteroid remains a vital choice for ARDS treatm…

Albi Francis, Yogendra Nayak

pp. 69–77 · DOI: 10.5530/jyp.2017.9.14

Introduction: Severe cardiotoxicity limits the use of doxorubicin in cancer treatment. Doxorubicin toxicity involves the generation of reactive oxygen species (ROS) and hence several antioxidants and plant products have …

Divya Jyothi, Sneh Priya, Jainey P James

pp. 78–82 · DOI: 10.5530/jyp.2017.9.15

Objective:Present study is aimed at formulation of hydrogel containing PLGA nanoparticles loaded with of Crossandra infundibuliformis (CI) extract. Leaf extract of Crossandra infundibuliformis has been reported to posses…

Eryati Darwin, Eka Fithra Elf, Dachriyanus d

pp. 83–86 · DOI: 10.5530/jyp.2017.9.16

Objective: The aim with the present study was to determine that arginine affect to the level of IL-6, IL-17 and TGF-β in high-fat diet-induced hyper cholesterolemia in rats. Material and Methods: Male Wistar rats in eigh…

Anoop Narayanan V, Praveena George, Dhamelia Akshay L

pp. 87–93 · DOI: 10.5530/jyp.2017.9.17

Objective:In the present study, our objective was to develop porous osmotic pump tablets of an anti-Parkinson’s agent, ropinirole. It also aimed to demonstrate the applicability of factorial designs and there by a statis…

Raja Navamanisubramanian, Raghunandan Nerella, Chamundeeswari D, Shanmuganathan Seetharaman

pp. 94–99 · DOI: 10.5530/jyp.2017.9.18

Objective:Transmucosal buccal drug delivery could be an alternative for oral administration for systemic delivery of Verapamil Hydrochloride (VH), as it has low bioavailability 20 - 35 % due to its extensive first pass m…

Anroop Balachandran Nair, Abbas Ahmed Al-ghannam, Bandar Essa Al-Dhubiab, Azza Ali Hasan

pp. 100–105 · DOI: 10.5530/jyp.2017.9.19

Objective:The efficiency of acyclovir, a potent antiviral agent, is mainly limited by its low permeability.The purpose of this investigation was to formulate and assess nanoparticle impregnated buccal films to improve ac…

Rambabu Maddela, Nageswara Rao Pilli, Srinubabu Maddela, Chalapathi Rao Pulipati, Srinivasa Rao Polagani, Ajitha Makula

pp. 106–113 · DOI: 10.5530/jyp.2017.9.20

Objective: The main goal of this research was to develop a simple, rapid and sensitive liquid chromatography/tandem mass spectrometry (LC–MS/ MS) method for the simultaneous quantification of mycophenolate mofetil and my…