Journal of Young Pharmacists
Volume 2, Issue 2
· pp. 113–212 · 17 articles
- Volume
- 2
- Issue
- 2
- Published
- Pages
- 113–212
- Articles
- 17
- Sections
- 9
- ISSN
- Print - 0975-1483 | Online - 0975-1505
- Journal
- JYP
In this issue
Editorial
- Forum Article
Conflict of Interest in Peer-Reviewed Medical Journals: The World Association of Medical Editors Position on a Challenging Problem
Ferris LE, Fletcher RH
pp. 113–115 · DOI: 10.4103/0975-1483.63143 · Published
Conflict of interest in medical publishing exists when a participant’s private interests compete with his or her responsibilities to the scientific community, readers and society. While conflict of interest is common, it…
Pharmaceutics
- Article
Studies on In situ Hydrogel: A Smart Way for Safe and Sustained Ocular Drug Delivery
Shastri DH, Patel LD, Parikh RK
pp. 116–120 · DOI: 10.4103/0975-1483.63144 · Published
The present work describes the formulation development of ophthalmic in situ gelling system using thermoreversible gelling polymer, i.e. Pluronic F 127 (PF127). Because of high concentration (20 to 25%w/v) of this polyme…
- Article
Formulation and Evaluation of Extended-Release Solid Dispersion of Metformin Hydrochloride
Patil SA, Kuchekar BS, Chabukswar AR, Jagdale SC
pp. 121–129 · DOI: 10.4103/0975-1483.63147 · Published
The purpose of this research was to formulate and characterize solid dispersion (SD) of metformin hydrochloride using methocel K100M as the carrier by the solvent evaporation and cogrinding method. The influence of drug …
Pharmacognosy
- Article
Aqueous Extract of Ficus bengalensis Linn. Bark for Inflammatory Bowel Disease
Patel MA, Patel PK, Patel MB
pp. 130–136 · DOI: 10.4103/0975-1483.63149 · Published
The present study was designed to evaluate the effects of aqueous extract of Ficus bengalensis Linn. bark (AEFB) on inflammatory bowel disease (IBD). Effects of AEFB were studied on 2, 4, 6-trinitrobenzenesulfonic acid (…
- Article
Antioxidant, Antinociceptive and Anti-inflammatory Activities of Ethanolic Extract of Leaves of Alocasia indica (Schott.)
Mulla WA, Kuchekar SB, Thorat VS, Chopade AR, Kuchekar BS
pp. 137–14 · DOI: 10.4103/0975-1483.63152 · Published
Extracts obtained from the leaves of various Alocasia species have been used in India as folk remedy for the treatment of various inflammatory ailments including rheumatism and bruise. The ethanolic extract of leaves of …
Pharmacology
- Article
Glucagon Secreting Cells Responds to Insulin Secretion In vitro Using Immunocytochemistry
Aswar MK, Aswar UM, Subhedar NK
pp. 144–147 · DOI: 10.4103/0975-1483.63154 · Published
In the present study, pancreas of rats were dissected and transferred to HEPES buffer (25 mM, pH 7.4). The control tissue pieces were kept in culture medium for one hour and the treated tissues were kept in same medium f…
- Article
Possible Role of Hydrogen Sulfide in Insulin Secretion and in Development of Insulin Resistance
Patel MA, Shah GB
pp. 148–151 · DOI: 10.4103/0975-1483.63156 · Published
H2S has been proposed as physiological important molecule. It is considered as first endogenous gaseous K+ channel opener. K+ATP channel activity is mainly responsible for insulin secretion. K+ATP channel opening of β ce…
- Article
Drug–Drug Interaction between Pravastatin and Gemfibrozil (Antihyperlipidemic) with Gliclazide (Antidiabetic) in Rats
Sultanpur CM, Satyanarayana S, Reddy NS, Kumar KE, Kumar S
pp. 152–155 · DOI: 10.4103/0975-1483.63157 · Published
Diabetes mellitus is a condition of increased blood glucose level in the body. Antihyperlipidemic drugs like statins and fibrates are widely used for prophylactic treatment in dyslipideamia and atherosclerosis. Diabetic …
- Article
A Novel Approach for Oral Delivery of Insulin via Desmodium gangeticum Aqueous Root Extract
Kurian GA, Seetharaman AV, Seetharaman NR, Paddikkala J
pp. 156–161 · DOI: 10.4103/0975-1483.63158 · Published
Many challenges are associated with the oral delivery of insulin, relating to the physical and chemical stability of the hormone, and its absorption and metabolism in the human body. The present study aims to demonstrate…
Pharmaceutical Chemistry
- Article
Synthesis and Pharmacological Evaluation of Novel Schiff Base Analogues of 3-(4-amino) Phenylimino) 5-fluoroindolin-2-one
R Nirmal, CR Prakash, K Meenakshi, P Shanmugapandiyan
pp. 162–168 · DOI: 10.4103/0975-1483.63162 · Published
In our study, a series of novel 3-(4-(benzylideneamino) phenylimino) 4-fluoroindolin-2-one derivatives were synthesized and characterized by spectral (I.R, 1H NMR, mass) and elemental analysis. The title compounds (N1-N1…
- Article
Synthesis and Evaluation of 1,3 Di-Substituted Schiff, Mannich Bases and Spiro Isatin Derivatives
Mondal P, Banerjee M, Jana S, Bose A
pp. 169–172 · DOI: 10.4103/0975-1483.63164 · Published
Schiff bases of isatin with aminothiazole, its N-mannich bases and Spiro isatin derivatives were synthesized. Their chemical structures were confirmed by Infrared, 1H-Nuclear Magnetic Resonance data and elemental analysi…
- Article
Synthesis and Antimicrobial Activity of 2-[2-(2,6-dichloro phenyl) amino]benzyl-3-(5-substituted phenyl-4,5-dihydro-1H-pyrazol-3-ylamino)- 6,8-dibromoquinazolin-4(3H)ones
Patel NB, Patel JC, Barat GG
pp. 173–182 · DOI: 10.4103/0975-1483.63165 · Published
A series of 2-[2-(2,6-dichlorophenyl)amino]benzyl-3-(5-substituted phenyl-4,5-dihydro-1H-pyrazol-3-yl-amino)- 6,8-dibromoquinazolin-4(3H) ones 6a-m have been synthesized by the reaction of 2-[2-(2,6-dichlorophenyl) amino…
Pharmaceutical Analysis
- Article
Development and Validation of a Specific Stability Indicating High Performance Liquid Chromatographic Method for Valsartan
Rao KS, Jena N, Rao MEB
pp. 183–189 · DOI: 10.4103/0975-1483.63166 · Published
A stability-indicating HPLC assay method has been developed and validated for valsartan in bulk drug and pharmaceutical dosage forms. An isocratic RP-HPLC was achieved on Waters 2695 using Symmetry C18 (250mm × 4.6mm × 5…
- Article
Comparative Study of RP-HPLC and UV Spectrophotometric Techniques for the Simultaneous Determination of Amoxicillin and Cloxacillin in Capsules
Giang Do T, Hoang Vu D
pp. 190–195 · DOI: 10.4103/0975-1483.63168 · Published
Reversed-phase HPLC and UV spectrophotometric techniques using water as solvent have been developed and validated for the simultaneous determination of amoxicillin and cloxacillin in capsules. For both techniques, the li…
Pharmacy Practice
- Article
In vivo and In vitro Drug Interactions Study of Glimepride with Atorvastatin and Rosuvastatin
Galani VJ, Vyas M
pp. 190–200 · DOI: 10.4103/0975-1483.63169 · Published
Aim of this investigation was to study the in vivo and in vitro drug interaction of glimepride with atorvastatin and rosuvastatin. In vitro drug interaction of glimepride with atorvastatin and rosuvastatin was studied us…
Pharmaceutical Management
- Article
ABC and VED Analysis of the Pharmacy Store of a Tertiary Care Teaching, Research and Referral Healthcare Institute of India
Devnani M, Gupta AK, Nigah R
pp. 201–205 · DOI: 10.4103/0975-1483.63170 · Published
The ABC and VED (vital, essential, desirable) analysis of the pharmacy store of Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India, was conducted to identify the categories of items nee…
General Pharmacy
- Article
Recent Trends on the Future of Graduate Education in the Pharmaceutical Sciences and Research
Kushwaha KSS, Kushwaha N, Rai AK
pp. 206–212 · DOI: 10.4103/0975-1483.63173 · Published
Harmonization of pharmacy education has to be made a global agenda that will encompass the developments that have taken place in basic, medical, pharmaceutical sciences in serving the needs and expectations of the societ…