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Journal of Young Pharmacists volume 2, issue 3 cover
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Cover: Journal of Young Pharmacists

Journal of Young Pharmacists

Volume 2, Issue 3

· pp. 213–336 · 25 articles

Volume
2
Issue
3
Published
Pages
213–336
Articles
25
Sections
10
ISSN
Print - 0975-1483 | Online - 0975-1505
Journal
JYP
EditorialPharmaceuticsPharmacognosyPharmacologyPharm ChemistryPharm AnalysisPharmacy PracticeClinical PharmacyGeneral PharmacyLetter to Editor

In this issue

Editorial

  1. Forum Article

    Refining a Research Manuscript

    Ambikanandan Misra

    pp. 213–215 · DOI: 10.4103/0975-1483.66788 · Published

    The article begins with the abstract, which is summary of the research work. It is a concise and focused representation of research work indicating the aim of the study, the methods used, results and major findings as a …

Pharmaceutics

  1. Article

    Fast Dissolving Sublingual Films of Ondansetron Hydrochloride: Effect of Additives on in vitro Drug Release and Mucosal Permeation

    Koland M, Sandeep VP, CharyuluCharyulu NR

    pp. 216–222 · DOI: 10.4103/0975-1483.66790 · Published

    Ondansetron hydrochloride, a 5 HT3 antagonist is a powerful antiemetic drug which has oral bioavailability of 60% due to hepatic first pass metabolism and has a short half-life of 5 h. To overcome the above draw back, th…

  2. Article

    Preparation, Characterization and in vivo Evaluation of Parenteral Sustained Release Microsphere Formulation of Zopiclone

    Swapna N, Jithan AV

    pp. 223–228 · DOI: 10.4103/0975-1483.66792 · Published

    The aim of this study was to prepare zopiclone-loaded polycaprolactone microspheres by emulsion solvent evaporation technique with different drug-to-carrier ratios {MP 1 (1:1), MP 2 (1:2), MP 3 (1:3), and MP 4 (1:4)}, ch…

  3. Article

    Influence of Organic Acids on Diltiazem HCl Release Kinetics from Hydroxypropyl Methyl Cellulose Matrix Tablets

    Sateesha SB, Rajamma AJ, Narode MK, Vyas BD

    pp. 229–233 · DOI: 10.4103/0975-1483.66793 · Published

    The matrix tablets of diltiazem hydrochloride were prepared by direct compression using hydroxypropyl methyl cellulose (HPMC) and various amounts (2.5%, 5.0%, 10% and 20%) of citric acid, malic acid and succinic acid. Th…

  4. Article

    Formulation Development, Evaluation and Comparative Study of Effects of Super Disintegrants in Cefixime Oral Disintegrating Tablets

    Remya KS, Beena P, Bijesh PV, Sheeba A

    pp. 234–239 · DOI: 10.4103/0975-1483.66794 · Published

    The present work was aimed at formulation development, evaluation and comparative study of the effects of superdisintegrants in Cefixime 50 mg oral disintegrating tablets. The superdisintegrants used for the present stud…

  5. Article

    Formulation and Characterization of Patient-Friendly Dosage Form of Ondansetron Hydrochloride

    Bhoyar PK, Biyani DM, Umekar MJ

    pp. 240–246 · DOI: 10.4103/0975-1483.66796 · Published

    Ondansetron hydrochloride is an intensely bitter antiemetic drug used to treat nausea and vomiting following chemotherapy. The purpose of the present work was to mask the taste of ondansetron hydrochloride and to formula…

  6. Article

    Molecular Properties and Evaluation of Indion 234–Ondansetron Resinates

    Shah S, Pandya S, Bhalekar MR

    pp. 247–251 · DOI: 10.4103/0975-1483.66799 · Published

    Ondansetron is a serotonin 5HT3 antagonist; anti-emetic drug. Bitter taste of the ondansetron is a major problem in ensuring patient compliance. The study was designed to formulate tasteless complexes of ondansetron with…

Pharmacognosy

  1. Article

    Cytomorphological Studies on Stem of Luffa echinata Roxb

    Jayalakshmi S, Patra A, Wahi AK

    pp. 252–254 · DOI: 10.4103/0975-1483.66800 · Published

    Luffa echinata Roxb., commonly known as Bindal in Hindi is used for its hypoglycemic activity in the indigenous system of medicine. No pharmacognostical study on stem is reported in the literature till date; therefore, i…

  2. Article

    In vivo Antidiabetic and Antioxidant Potential of Stephania hernandifolia in Streptozotocin-Induced-Diabetic Rats

    Sharma U, Sahu RK, Roy A, Golwala DK

    pp. 255–260 · DOI: 10.4103/0975-1483.66803 · Published

    Stephania hernandifolia (Menispermaceae) is a medicinal plant, used by herbalists for treating various diseases, one of which is diabetes mellitus, in Darjeeling. However, its antidiabetic activity has not been scientifi…

Pharmacology

  1. Article

    Spasmolytic Activity of Fruits of Tamarindus indica L.

    Ali N, Shah SWA

    pp. 261–264 · DOI: 10.4103/0975-1483.66805 · Published

    Objective:To study the possible effects of methanolic extract of fruits of Tamarindus indica on rabbit’s jejunum preparations. Materials and Methods:The study was carried out on rabbit’s jejunum preparations. Methanolic …

  2. Article

    Aqueous Extract of Garcinia indica Choisy Restores Glutathione in Type 2 Diabetic Rats

    Kirana H, Srinivasan BP

    pp. 265–268 · DOI: 10.4103/0975-1483.66806 · Published

    Significant depletion of glutathione (GSH-reduced form) was observed in type 2 diabetes due to oxidative stress. Hence the present study was aimed to investigate a drug which restores GSH along with its anti-diabetic act…

  3. Article

    Evaluation of the Effect of Lime Fruit Juice on the Anticoagulant Effect of Warfarin

    Adepoju GKA, Adeyemi T

    pp. 269–272 · DOI: 10.4103/0975-1483.66808 · Published

    Aim:Citrus aurantifolia (Family Rutaceae) is commonly known as a familiar food and medicine, and s therapeutic effectiveness in a variety of diseases has been suggested in traditional medicine. Various complementary and …

Pharm Chemistry

  1. Article

    Synthesis, Characterization, and Biological Evaluation of Benzimidazole Derivatives as Potential Anxiolytics

    Nannapaneni DT, Gupta Atyam VSSS, Reddy MI, Sarva Raidu Ch

    pp. 273–279 · DOI: 10.4103/0975-1483.66809 · Published

    The synthesized benzimidazoles compounds were prepared from the condensation reaction between o-Phenylenediamine and various carbonyl compounds, in the presence of ammonium chloride as a catalyst. Ammonium chloride is a …

Pharm Analysis

  1. Article

    Liquid Chromatographic Determination of Flavoxate HCl in Pharmaceutical Formulation

    Attimarad M

    pp. 280–283 · DOI: 10.4103/0975-1483.66787 · Published

    The objective of the study was to develop a high performance liquid chromatography (HPLC) method using ultra violet (UV) detection for the determination of flavoxate HCl in bulk and solid dosage forms by using ibuprofen …

  2. Article

    Development and Validation of Spectrophotometric Methods for the Estimation of Mesalamine in Tablet Dosage Forms

    Patel KM, Patel CN, Panigrahi B, Parikh AS, Patel HN

    pp. 284–288 · DOI: 10.4103/0975-1483.66789 · Published

    Three simple and sensitive visible spectrophotometric methods (A, B, and C) have been developed for the quantitative estimation of mesalamine in bulk drug and pharmaceutical dosage forms. Methods were based on the format…

  3. Article

    Spectrophotometric and Reversed-Phase High-Performance Liquid Chromatographic Method for the Determination of Doxophylline in Pharmaceutical Formulations

    Joshi HR, Patel AH, Captain AD

    pp. 289–296 · DOI: 10.4103/0975-1483.66791 · Published

    Two methods are described for determination of Doxophylline in a solid dosage form. The first method was based on ultraviolet (UV)-spectrophotometric determination of the drug. It involves absorbance measurement at 274 n…

  4. Article

    Analysis of Monosodium l-Glutamate in Food Products by High- Performance Thin Layer Chromatography

    Krishna Veni N, Surya Devi M, Rubini MF, Vishalini M, Pradeepa YJ

    pp. 297–300 · DOI: 10.4103/0975-1483.66795 · Published

    A simple, fast, specific, and precise high-performance thin layer chromatography method has been developed for the estimation of monosodium l-glutamate (MSG) in food products. Aluminum plates precoated with silica gel 60…

Pharmacy Practice

  1. Article

    Assessment of Awareness among Clinicians about Concepts in Undergraduate Pharmacology Curriculum: A Novel Crosssectional Study

    Mahajan R, Singh NR, Singh J, Dixit A, Jain A, Gupta A

    pp. 301–305 · DOI: 10.4103/0975-1483.66797 · Published

    Objective:In the last 30 years, concepts in pharmacology have moved from Essential Medicines (EM) to P-drugs via the Rational Use of Medicines (RUM), but no structured study has evaluated the level of understanding among…

  2. Article

    Assessment of Self-Medication Practices Among Medical, Pharmacy, and Health Science Students in Gondar University, Ethiopia

    Abay SM, Amelo W

    pp. 306–310 · DOI: 10.4103/0975-1483.66798 · Published

    The study was aimed at assessing the magnitude and factors of self-medication among medical, pharmacy, and health science students of GCMHS (Gondar College of Medicine and Health Sciences). A cross-sectional study with t…

Clinical Pharmacy

  1. Article

    Pharmacotherapy-Based Problems in the Management of Diabetes Mellitus: Needs Much More to be Done!

    Ali N, Shah SWA, Khan J, Rehman S, Imran M, Hussian I, Shehbaz N, Jamshed H, Khan S

    pp. 311–314 · DOI: 10.4103/0975-1483.66801 · Published

    A total of 856 diabetic patients were evaluated for pharmacotherapy-based problems like for possible drug interactions, adverse drug reactions, and other mismatches, if any. Poor correlation between the advised insulin t…

General Pharmacy

  1. Article

    Pharmacovigilance: A Worldwide Master Key for Drug Safety Monitoring

    Jeetu G, Anusha G

    pp. 315–320 · DOI: 10.4103/0975-1483.66802 · Published

    Pharmacovigilance is like a sunshade to describe the processes for monitoring and evaluating ADRs and it is a key component of effective drug regulation systems, clinical practice and public health programmes. The number…

  2. Article

    To Recognize the Use of International Standards for Making Harmonized Regulation of Medical Devices in Asia-Pacific

    Anand K, Saini KS, Chopra Y, Binod SK

    pp. 321–325 · DOI: 10.4103/0975-1483.66804 · Published

    ‘Medical Devices’ include everything from highly sophisticated, computerized, medical equipment, right down to simple wooden tongue depressors. Regulations embody the public expectations for how buildings and facilities …

  3. Article

    Drug Interaction and Pharmacist

    Ansari JA

    pp. 326–331 · DOI: 10.4103/0975-1483.66807 · Published

    The topic of drug–drug interactions has received a great deal of recent attention from the regulatory, scientific, and health care communities worldwide. Nonsteroidal anti-inflammatory drugs, antibiotics and, in particul…

  4. Article

    TGN1412: From Discovery to Disaster

    Attarwala H

    pp. 332–336 · DOI: 10.4103/0975-1483.66810 · Published

    After a drug is confirmed as safe and efficacious in preclinical studies, it is tested in healthy human volunteers for first in man trials. In 2006, a phase I clinical study was conducted for a CD28 superagonist antibody…

Letter to Editor

  1. Article

    Ayurveda and Urinary Tract Infections

    Jain R, Kosta S, Tiwari A

    pp. 337 · DOI: · Published

    Sir, Urinary tract infections (UTIs), the second most common type of infection in the body is one the most serious health problem affecting millions of people each year. The urinary tract infection (UTI) involves infecti…