Journal of Young Pharmacists
Volume 5, Issue 4
· pp. 111–196 · 17 articles
- Volume
- 5
- Issue
- 4
- Published
- Pages
- 111–196
- Articles
- 17
- Sections
- 5
- ISSN
- Print - 0975-1483 | Online - 0975-1505
- Journal
- JYP
In this issue
Editorial
- Forum Article
Late effect clinic e An integral part of childhood cancer treatment
Biswajit B
pp. 111 · DOI: 10.1016/j.jyp.2014.01.001 · Published
The age adjusted incidence rate of childhood cancer in India is 38e124 per million children per year. The most common malignancies in childhood include Leukaemia, Lymphoma and Brain tumours.1 The 5 year overall survival …
Review Article
- Review
Bedaquiline e The first ATP synthase inhibitor against multi drug resistant tuberculosis
Mageshwaran Lakshmanan, Alphienes Stanley Xavier
pp. 112–115 · DOI: 10.1016/j.jyp.2013.12.002 · Published
Increasing incidence of MDR-TB, long duration of treatment and co-infection with HIV are the significant problems in achieving the eradication of tuberculosis. Bedaquiline is an anti-tuberculosis drug with unique mechani…
- Review
Adverse drug reaction and concepts of drug safety in Ayurveda: An overview
Manjunath Ajanal, Shradda Nayak, Buduru Sreenivasa Prasad, Avinash Kadam
pp. 116–120 · DOI: 10.1016/j.jyp.2013.10.001 · Published
Drug safety is a very basic and fundamental concept in medical practice. ADRs play an important role in assessing patient safety in any system of medicine. Pharmacovigilance study is thus significant to understand treatm…
Original Artcile
- Article
Molecular characterization and its antioxidant activity of a newly isolated Streptomyces coelicoflavus BC 01 from mangrove soil
Kothagorla Venkata Raghava Rao, Tamanam Raghava Rao
pp. 121–126 · DOI: 10.1016/j.jyp.2013.10.002 · Published
Objective: To isolate and identify the biologically active strain of Streptomyces species from mangrove soil of Visakhapatnam region. Materials and methods: Actinomycetes are isolated by using starch casein agar media an…
- Article
Simultaneous estimation of degree of crystallinity in combination drug product of abacavir, lamivudine and neverapine using X-ray powder diffraction technique
Pavan Kommavarapu, Arthanareeswari Maruthapillai, Ravikiran Allada, Kamaraj Palanisamy, Praveen Chappa
pp. 127–132 · DOI: 10.1016/j.jyp.2013.10.003 · Published
Objective: In the present study, simultaneous determination of degree of crystallinity content in abacavir (ABC), lamivudine (3TC) and neverapine (NVP) from there combination drug product using X-ray powder diffraction (…
- Article
Development and validation of RP-HPLC method with ultraviolet detection for estimation of montelukast in rabbit plasma: Application to preclinical pharmacokinetics
Om Prakash Ranjan, Usha Y. Nayak, Meka Sreenivasa Reddy, Swapnil J. Dengale, Prashant B. Musmade, Nayanabhirama Udupa
pp. 133–138 · DOI: 10.1016/j.jyp.2013.10.006 · Published
Objective: To develop a liquid–liquid extraction based reverse phase liquid chromatography method for estimation of montelukast in rabbit plasma. Methods: Chromatographic separation was carried out using Phenomenex Luna …
- Article
Evaluation of quality and efficacy of an ethnomedicinal plant Ageratum conyzoides L. in the management of pediculosis
Sunita Shailajan, Priyanka Wadke, Harshvardhan Joshi, Bhavesh Tiwari
pp. 139–143 · DOI: 10.1016/j.jyp.2013.10.005 · Published
Background:Infestation with the head louse, Pediculus humanus capitis, is one of the most common parasitic infestations of human worldwide. Traditionally, the main treatment for control of head lice is chemical control t…
- Article
Prevalence and control of cardiovascular risk factors among type 2 diabetes mellitus patients in southern region of Saudi Arabia
Sirajudeen S. Alavudeen, C.K. Dhanapal, Noohu Abdulla Khan, Khalid M. Al Akhali, Sam Daniel Paulliah
pp. 144–147 · DOI: 10.1016/j.jyp.2013.11.006 · Published
Background/Aim: Dyslipidemia is a significant predictor of cardiovascular events and mortality in diabetes patients. The aim of this study is to estimate the prevalence rates, characteristics of dyslipidemia and their co…
- Article
Efficacy of Cinnamomum cassia Blume. in age induced sexual dysfunction of rats
Sumanta Kumar Goswami, Mohammed Naseeruddin Inamdar, Rohitash Jamwal, Shekhar Dethe
pp. 148–153 · DOI: 10.1016/j.jyp.2013.11.001 · Published
Objective:Cinnamomum cassia has been suggested in Ayurveda for the management of sexual dysfunction. This research work was conducted to shed some light on the mechanism of action of the extract, and evaluate the efficac…
- Article
Synthesis, characterisation and evaluation of N-mannich bases of 2-substituted Benzimidazole derivatives
Sekar Vinoth Kumar, Mohan Raj Subramanian, Santhosh Kumar Chinnaiyan
pp. 154–159 · DOI: 10.1016/j.jyp.2013.11.004 · Published
Rationale:Benzimidazoles and its derivatives represent one of the mainly biological active classes of literature. Aim:In this present study aimed to synthesize N-mannich bases derivatives compounds bearing of 2-substitut…
- Article
Chitosanepectin polyelectrolyte complex as a carrier for colon targeted drug delivery
Sonia Pandey, Ashish Mishra, Pooja Raval, Hetal Patel, Arti Gupta, Dinesh Shah
pp. 160–166 · DOI: 10.1016/j.jyp.2013.11.002 · Published
Objective:The objective of present work was to prepare a polyelectrolyte complex (PEC) between chitosan (polycation) & pectin (polyanion) and to develop enteric coated tablets for colon delivery using the PEC. Methodolog…
- Article
Design and in vitro/in vivo evaluation of extended release matrix tablets of nateglinide
Pushkar R. Sharma, Shaila A. Lewis
pp. 167–172 · DOI: 10.1016/j.jyp.2013.11.003 · Published
Aim:Nateglinide is a quick acting anti-diabetic medication whose potent activity lasts for a short duration. One of the dangerous side effects of nateglinide administration is rapid hypoglycemia, a condition that needs t…
- Article
In silico QSAR analysis of quercetin reveals its potential as therapeutic drug for Alzheimer’s disease
Md. Rezaul Islam, Aubhishek Zaman, Iffat Jahan, Rajib Chakravorty
pp. 173–179 · DOI: 10.1016/j.jyp.2013.11.005 · Published
Acetylcholine-esterase (AchE) inhibitors are one of the most potent drug molecules against Alzheimer’s disease (AD). But, patients treated with current AchE inhibitors often experience severe side effects. Quercetin is a…
- Article
Design and evaluation of herbal hepatoprotective formulation against paracetamol induced liver toxicity
Arti Gupta, Navin R. Sheth, Sonia Pandey, Dinesh R. Shah, Jitendra S. Yadav
pp. 180–187 · DOI: 10.1016/j.jyp.2013.12.003 · Published
Aim: To isolate and identify the quercetin from polyherbal hepatoprotective formulation. Polyherbal formulations were developed by using five bioactive fractionated extracts of Butea monosperma, Bauhinia variegata and Oc…
Short communication
- Communication
Herbs in association with drugs: Enhancement of the aminoglycosideantibiotic activity by Pityrogramma calomelanos (L.) Link
Teógenes M. Souza, Maria F.B. Morais-Braga, José G.M. Costa, Antônio A.F. Saraiva, Micheline A. Lima, Henrique D.M. Coutinho
pp. 188–190 · DOI: 10.1016/j.jyp.2013.10.004 · Published
Aims: In this work, the ethyl acetate and hexane fractions of Pityrogramma calomelanos (L.) were evaluated to antibacterial and antifungal activity against strains of Escherichia coli, Pseudomonas aeruginosa, Staphylococ…
- Communication
Isolation, biochemical and genetic characterizations of alcohol-producing yeasts from the flowers of Woodfordia fruticosa
Jagdish Manwar, Kakasaheb Mahadik, Anant Paradkar, Lohidasan Sathiyanarayanan, Mustafa Vohra, Sanjay Patil
pp. 191–194 · DOI: 10.1016/j.jyp.2013.11.007 · Published
Objective:To isolate and characterize the alcohol-producing yeasts from Woodfordia fruticosa flowers, which are used for the induction and maintenance of fermentation in the making of Ayurvedic formulations. Materials an…
Case Report
- Article
Doxycycline induced generalized bullous fixed drug eruption e A case report
Selvaraj Nitya, Kameswari Deepa, Adhimoolam Mangaiarkkarasi, Kaliaperumal Karthikeyan
pp. 195–196 · DOI: 10.1016/j.jyp.2013.12.001 · Published
Adverse drug reactions are a major hazard of modern medicine. Fixed drug eruption, which is a cutaneous adverse drug reaction, is commonly seen with antimicrobials and analgesics. Here we report 37- year-old female with …

