Journal of Young Pharmacists volume 5, issue 4 cover
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Cover: Journal of Young Pharmacists

Journal of Young Pharmacists

Volume 5, Issue 4

· pp. 111–196 · 17 articles

Volume
5
Issue
4
Published
Pages
111–196
Articles
17
Sections
5
ISSN
Print - 0975-1483 | Online - 0975-1505
Journal
JYP

In this issue

Editorial

  1. Forum Article

    Late effect clinic e An integral part of childhood cancer treatment

    Biswajit B

    pp. 111 · DOI: 10.1016/j.jyp.2014.01.001 · Published

    The age adjusted incidence rate of childhood cancer in India is 38e124 per million children per year. The most common malignancies in childhood include Leukaemia, Lymphoma and Brain tumours.1 The 5 year overall survival …

Review Article

  1. Review

    Bedaquiline e The first ATP synthase inhibitor against multi drug resistant tuberculosis

    Mageshwaran Lakshmanan, Alphienes Stanley Xavier

    pp. 112–115 · DOI: 10.1016/j.jyp.2013.12.002 · Published

    Increasing incidence of MDR-TB, long duration of treatment and co-infection with HIV are the significant problems in achieving the eradication of tuberculosis. Bedaquiline is an anti-tuberculosis drug with unique mechani…

  2. Review

    Adverse drug reaction and concepts of drug safety in Ayurveda: An overview

    Manjunath Ajanal, Shradda Nayak, Buduru Sreenivasa Prasad, Avinash Kadam

    pp. 116–120 · DOI: 10.1016/j.jyp.2013.10.001 · Published

    Drug safety is a very basic and fundamental concept in medical practice. ADRs play an important role in assessing patient safety in any system of medicine. Pharmacovigilance study is thus significant to understand treatm…

Original Artcile

  1. Article

    Molecular characterization and its antioxidant activity of a newly isolated Streptomyces coelicoflavus BC 01 from mangrove soil

    Kothagorla Venkata Raghava Rao, Tamanam Raghava Rao

    pp. 121–126 · DOI: 10.1016/j.jyp.2013.10.002 · Published

    Objective: To isolate and identify the biologically active strain of Streptomyces species from mangrove soil of Visakhapatnam region. Materials and methods: Actinomycetes are isolated by using starch casein agar media an…

  2. Article

    Simultaneous estimation of degree of crystallinity in combination drug product of abacavir, lamivudine and neverapine using X-ray powder diffraction technique

    Pavan Kommavarapu, Arthanareeswari Maruthapillai, Ravikiran Allada, Kamaraj Palanisamy, Praveen Chappa

    pp. 127–132 · DOI: 10.1016/j.jyp.2013.10.003 · Published

    Objective: In the present study, simultaneous determination of degree of crystallinity content in abacavir (ABC), lamivudine (3TC) and neverapine (NVP) from there combination drug product using X-ray powder diffraction (…

  3. Article

    Development and validation of RP-HPLC method with ultraviolet detection for estimation of montelukast in rabbit plasma: Application to preclinical pharmacokinetics

    Om Prakash Ranjan, Usha Y. Nayak, Meka Sreenivasa Reddy, Swapnil J. Dengale, Prashant B. Musmade, Nayanabhirama Udupa

    pp. 133–138 · DOI: 10.1016/j.jyp.2013.10.006 · Published

    Objective: To develop a liquid–liquid extraction based reverse phase liquid chromatography method for estimation of montelukast in rabbit plasma. Methods: Chromatographic separation was carried out using Phenomenex Luna …

  4. Article

    Evaluation of quality and efficacy of an ethnomedicinal plant Ageratum conyzoides L. in the management of pediculosis

    Sunita Shailajan, Priyanka Wadke, Harshvardhan Joshi, Bhavesh Tiwari

    pp. 139–143 · DOI: 10.1016/j.jyp.2013.10.005 · Published

    Background:Infestation with the head louse, Pediculus humanus capitis, is one of the most common parasitic infestations of human worldwide. Traditionally, the main treatment for control of head lice is chemical control t…

  5. Article

    Prevalence and control of cardiovascular risk factors among type 2 diabetes mellitus patients in southern region of Saudi Arabia

    Sirajudeen S. Alavudeen, C.K. Dhanapal, Noohu Abdulla Khan, Khalid M. Al Akhali, Sam Daniel Paulliah

    pp. 144–147 · DOI: 10.1016/j.jyp.2013.11.006 · Published

    Background/Aim: Dyslipidemia is a significant predictor of cardiovascular events and mortality in diabetes patients. The aim of this study is to estimate the prevalence rates, characteristics of dyslipidemia and their co…

  6. Article

    Efficacy of Cinnamomum cassia Blume. in age induced sexual dysfunction of rats

    Sumanta Kumar Goswami, Mohammed Naseeruddin Inamdar, Rohitash Jamwal, Shekhar Dethe

    pp. 148–153 · DOI: 10.1016/j.jyp.2013.11.001 · Published

    Objective:Cinnamomum cassia has been suggested in Ayurveda for the management of sexual dysfunction. This research work was conducted to shed some light on the mechanism of action of the extract, and evaluate the efficac…

  7. Article

    Synthesis, characterisation and evaluation of N-mannich bases of 2-substituted Benzimidazole derivatives

    Sekar Vinoth Kumar, Mohan Raj Subramanian, Santhosh Kumar Chinnaiyan

    pp. 154–159 · DOI: 10.1016/j.jyp.2013.11.004 · Published

    Rationale:Benzimidazoles and its derivatives represent one of the mainly biological active classes of literature. Aim:In this present study aimed to synthesize N-mannich bases derivatives compounds bearing of 2-substitut…

  8. Article

    Chitosanepectin polyelectrolyte complex as a carrier for colon targeted drug delivery

    Sonia Pandey, Ashish Mishra, Pooja Raval, Hetal Patel, Arti Gupta, Dinesh Shah

    pp. 160–166 · DOI: 10.1016/j.jyp.2013.11.002 · Published

    Objective:The objective of present work was to prepare a polyelectrolyte complex (PEC) between chitosan (polycation) & pectin (polyanion) and to develop enteric coated tablets for colon delivery using the PEC. Methodolog…

  9. Article

    Design and in vitro/in vivo evaluation of extended release matrix tablets of nateglinide

    Pushkar R. Sharma, Shaila A. Lewis

    pp. 167–172 · DOI: 10.1016/j.jyp.2013.11.003 · Published

    Aim:Nateglinide is a quick acting anti-diabetic medication whose potent activity lasts for a short duration. One of the dangerous side effects of nateglinide administration is rapid hypoglycemia, a condition that needs t…

  10. Article

    In silico QSAR analysis of quercetin reveals its potential as therapeutic drug for Alzheimer’s disease

    Md. Rezaul Islam, Aubhishek Zaman, Iffat Jahan, Rajib Chakravorty

    pp. 173–179 · DOI: 10.1016/j.jyp.2013.11.005 · Published

    Acetylcholine-esterase (AchE) inhibitors are one of the most potent drug molecules against Alzheimer’s disease (AD). But, patients treated with current AchE inhibitors often experience severe side effects. Quercetin is a…

  11. Article

    Design and evaluation of herbal hepatoprotective formulation against paracetamol induced liver toxicity

    Arti Gupta, Navin R. Sheth, Sonia Pandey, Dinesh R. Shah, Jitendra S. Yadav

    pp. 180–187 · DOI: 10.1016/j.jyp.2013.12.003 · Published

    Aim: To isolate and identify the quercetin from polyherbal hepatoprotective formulation. Polyherbal formulations were developed by using five bioactive fractionated extracts of Butea monosperma, Bauhinia variegata and Oc…

Short communication

  1. Communication

    Herbs in association with drugs: Enhancement of the aminoglycosideantibiotic activity by Pityrogramma calomelanos (L.) Link

    Teógenes M. Souza, Maria F.B. Morais-Braga, José G.M. Costa, Antônio A.F. Saraiva, Micheline A. Lima, Henrique D.M. Coutinho

    pp. 188–190 · DOI: 10.1016/j.jyp.2013.10.004 · Published

    Aims: In this work, the ethyl acetate and hexane fractions of Pityrogramma calomelanos (L.) were evaluated to antibacterial and antifungal activity against strains of Escherichia coli, Pseudomonas aeruginosa, Staphylococ…

  2. Communication

    Isolation, biochemical and genetic characterizations of alcohol-producing yeasts from the flowers of Woodfordia fruticosa

    Jagdish Manwar, Kakasaheb Mahadik, Anant Paradkar, Lohidasan Sathiyanarayanan, Mustafa Vohra, Sanjay Patil

    pp. 191–194 · DOI: 10.1016/j.jyp.2013.11.007 · Published

    Objective:To isolate and characterize the alcohol-producing yeasts from Woodfordia fruticosa flowers, which are used for the induction and maintenance of fermentation in the making of Ayurvedic formulations. Materials an…

Case Report

  1. Article

    Doxycycline induced generalized bullous fixed drug eruption e A case report

    Selvaraj Nitya, Kameswari Deepa, Adhimoolam Mangaiarkkarasi, Kaliaperumal Karthikeyan

    pp. 195–196 · DOI: 10.1016/j.jyp.2013.12.001 · Published

    Adverse drug reactions are a major hazard of modern medicine. Fixed drug eruption, which is a cutaneous adverse drug reaction, is commonly seen with antimicrobials and analgesics. Here we report 37- year-old female with …