Journls PHARMACOGNOSY MAGAZINE Volume 12 · Issue 46S 11 May 2016 · pp. 0–302
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Pharmacognosy Magazine

Volume 12, Issue 46S

11 May 2016 · pp. 0–302 · 45 articles

Volume
12
Issue
46S
Published
11 May 2016
Pages
0–302
Articles
45
Sections
2
ISSN
Print - 0973-1296, Online - 0976-4062
Journal
PM

In this issue

Original Article

  1. Article

    In vitro Metabolism of Sodium 9‑dehydro‑17‑hydro‑ andrographolide‑19‑yl Sulfate in Rat Liver S9 by Liquid Chromatography–Mass Spectrometry Method

    Dongkun Zheng, Jun Shao, Weikang Chen, Yuehua Luo

    pp. S102–S108 · DOI: 10.4103/0973-1296.182194 · Published 11 May 2016

    Background: Sodium 9‑dehydro‑17‑hydro‑andrographolide‑19‑yl sulfate (DHAS) is the active ingredient of Xiyanping injection, a traditional Chinese medicine in clinical use. However, there has been no report about the meta…

  2. Article

    Effect of Procyanidin‑rich Extract from Natural Cocoa Powder on Cellular Viability, Cell Cycle Progression, and Chemoresistance in Human Epithelial Ovarian Carcinoma Cell Lines

    Shruti Taparia, Aparna Khanna

    pp. S109–S115 · DOI: 10.4103/0973-1296.182164 · Published 11 May 2016

    Background: Over the last 400 years, cocoa and chocolate have been described as having potential medicinal value, being consumed as a beverage or eaten as food. Concentration–dependant, antiproliferation, and cytotoxic e…

  3. Article

    Effect of Withinia Somnifera and Shilajit on Alcohol Addiction in Mice

    Priya Bansal, Sugato Banerjee

    pp. S121–S128 · DOI: 10.4103/0973-1296.182170 · Published 11 May 2016

    Background: Alcohol addiction is a social problem leading to both loss of health and economic prosperity among addicted individuals. Common properties of anti‑addictive compounds include anti‑anxiety, anticonvulsants, an…

  4. Article

    Flavonoids Derived from Abelmoschus esculentus Attenuates UV-B Induced Cell Damage in Human Dermal Fibroblasts Through Nrf2-ARE Pathway

    Juilee Patwardhan, Purvi Bhatt

    pp. S129–S138 · DOI: 10.4103/0973-1296.182175 · Published 11 May 2016

    Background: Ultraviolet‑B (UV‑B) radiation is a smaller fraction of the total radiation reaching the Earth but leads to extensive damage to the deoxyribonucleic acid (DNA) and other biomolecules through formation of free…

  5. Article

    Epicatechin Plus Treadmill Exercise are Neuroprotective Against Moderate‑stage Amyloid Precursor Protein/Presenilin 1 Mice

    Zhiyuan Zhang, Hao Wu, Houcai Huang

    pp. S139–S146 · DOI: 10.4103/0973-1296.182174 · Published 11 May 2016

    Background: Epidemiological evidence suggests that exercise and dietary polyphenols are beneficial in reducing Alzheimer’s disease (AD) risk. Materials and Methods: In the present study, 8 months old amyloid precursor pr…

  6. Article

    Protective Effect of High Molecular Weight Protein Sub‑fraction of Calotropis procera Latex in Monoarthritic Rats

    Priyanka Chaudhary, Marcio V. Ramos, Mirele da Silveira Vasconcelos, Vijay L. Kumar

    pp. S147–S151 · DOI: 10.4103/0973-1296.182151 · Published 11 May 2016

    Background: Proteins present in the latex of Calotropis procera have been shown to produce anti‑inflammatory effect and to afford protection in various disease models. Objectives: To determine the efficacy of high molecu…

  7. Article

    Reversed Phase High‑Performance Liquid Chromatographic Ultra‑violet (Photo Diode Array) Quantification of Oleanolic Acid and its Isomer Ursolic Acid for Phytochemical Comparison and Pharmacological Evaluation of Four Leucas Species Used in Ayurveda

    Pushpendra Kumar Shukla, Ankita Misra, Sharad Srivastava, Ajay K. S. Rawat

    pp. S159–S164 · DOI: 10.4103/0973-1296.182173 · Published 11 May 2016

    Objective: Evaluation of four industrially important Leucas species for their in vitro antidiabetic potential and radical scavenging effect along with high‑performance liquid chromatographic quantification of the bioacti…

  8. Article

    DNA Barcoding Identification of Kadsurae Caulis and Spatholobi Caulis Based on Internal Transcribed Spacer 2 Region and Secondary Structure Prediction

    Xiaoxue Yu, Zhiyong Xie, Junwei Wu, Junfei Tao, Xinjun Xu

    pp. S165–S169 · DOI: 10.4103/0973-1296.182162 · Published 11 May 2016

    Background: Kadsurae Caulis and Spatholobi Caulis have very similar Chinese names. Their commodities were hard to distinguish because their stems were very alike after dried and processed. These two herbal drugs were oft…

  9. Article

    Cardioprotective and Antioxidant Influence of Aqueous Extracts from Sesamum indicum Seeds on Oxidative Stress Induced by Cadmium in Wistar Rats

    Babatunji Emmanuel Oyinloye, Basiru Olaitan Ajiboye, Oluwafemi Adeleke Ojo, Sarah Onyenibe Nwozo, Abidemi Paul Kappo

    pp. S170–S174 · DOI: 10.4103/0973-1296.182155 · Published 11 May 2016

    Background: Oxidative stress has been implicated in the pathogenesis of several acute and chronic diseases of the heart as a result of indiscriminate exposure to cardiotoxic heavy metals. The study reported here was desi…

  10. Article

    Minimization of the Risk of Diabetic Microangiopathy in Rats by Nigella sativa

    Juraiporn Somboonwong, Mariem Yusuksawad, Somboon Keelawat, Sirima Thongruay, Ubon Poumsuk

    pp. S175–S180 · DOI: 10.4103/0973-1296.182169 · Published 11 May 2016

    Background: Microangiopathy is a chronic diabetic complication resulting from metabolic derangements, oxidative stress, and increased pro‑inflammatory cytokine production. Nigella sativa Linn. is used as an herbal medici…

  11. Article

    High Performance Liquid Chromatography‑mass Spectrometry Analysis of High Antioxidant Australian Fruits with Antiproliferative Activity Against Cancer Cells

    Joseph Sirdaarta, Anton Maen, Paran Rayan, Ben Matthews, Ian Edwin Cock

    pp. S181–S194 · DOI: 10.4103/0973-1296.182178 · Published 11 May 2016

    Background: High antioxidant capacities have been linked to the treatment and prevention of several cancers. Recent reports have identified several native Australian fruits with high antioxidant capacities. Despite this,…

  12. Article

    The Anticholinesterase Properties of Plants from the Northeast of Brazil Selected by an Ethnopharmacological Study for Disorders Relating to the Nervous System

    Valerium Thijan Nobre de Almeida e Castro, Tadeu Jose da Silva Peixoto Sobrinho, Allan Jonathan Chernichiarro Corrêa, Thiago Antonio de Sousa Araújo, Terezinha Gonçalves Da Silva, Elba Lucia Cavalcanti de Amorim

    pp. S195–S200 · DOI: 10.4103/0973-1296.182166 · Published 11 May 2016

    Background: Various factors may trigger Alzheimer’s disease and the cholinergic hypothesis, which is one of the most widely accepted, argues damage to the brain nuclei, may reduce the production of the choline acetyltran…

  13. Article

    S201 Intrathecal Injection of Resveratrol Attenuates Burn Injury Pain by Activating Spinal Sirtuin 1

    Wei Cheng, Jin‑Feng Wang, Cong‑Xian Yang, Liang Wu, Qin Yin, He Liu, Zhi‑Jian Fu

    pp. S201–S205 · DOI: 10.4103/0973-1296.182167 · Published 11 May 2016

    Objective: The present study sought to detect spinal sirtuin 1 (SIRT1) and acetylation of histone H3 (Ac‑H3) expression in rats with burn injury pain (BIP model). Procedures and Results: A BIP model was first established…

  14. Article

    Evaluation of Xanthine Oxidase Inhibitory Potential and In vivo Hypouricemic Activity of Dimocarpus longan Lour. Extracts

    Shi-Yuan Sheu, Yuan-Tsung Fu, Wen-Dar Huang, Yung-Ann Chen, Yi-Chih Lei, Chun-Hsu Yao, Feng-Lin Hsu, Tzong-Fu Kuo

    pp. S206–S212 · DOI: 10.4103/0973-1296.182176 · Published 11 May 2016

    Background: Longan is a fruit tree known to contain many phenolic components, which are capable of protecting people from oxidative damage through an anti‑inflammatory mechanism. It may be also worthwhile to study the ef…

  15. Article

    Ketosteroid Standardized Cissus quadrangularis L. Extract and its Anabolic Activity: Time to Look Beyond Ketosteroid?

    Atul N. Jadhav, Mohammed Rafiq, Rajendran Devanathan, Mohammed Azeemuddin, Suryakanth D. Anturlikar, Akhil Ahmed, Ramchandran Sundaram, U. V. Babu, Rangesh Paramesh

    pp. S213–S217 · DOI: 10.4103/0973-1296.182177 · Published 11 May 2016

    Background: Cissus quadrangularis (CQ) L. reported to contain 3‑ketosteroids and have bone health benefits. Aim: This study aimed at establishing the relationship between the ketosteroid content and anabolic as well as b…

  16. Article

    Pyrostegia venusta (Ker Gawl.) Miers Crude Extract and Fractions: Prevention of Dental Biofilm Formation and Immunomodulatory Capacity

    Mayara Brito de Sousa, José Otávio Carrera Silva Júnior, Wagner Luiz Ramos Barbosa, Erika da Silva Valério, Andriele da Mata Lima, Marlon Heggdorne de Araújo, Michelle Frazão Muzitano, Celso Vataru Nakamura, João Carlos Palazzo de Mello, Francisco Martins Teixeira

    pp. S218–S222 · DOI: 10.4103/0973-1296.182150 · Published 11 May 2016

    Background: Caries and periodontal diseases remain as important diseases in the Brazilian population. One important pathogen associated with this situation is Streptococcus mutans and other important factor is this patho…

  17. Article

    Phytochemicals from Tradescantia albiflora Kunth Extracts Reduce Serum Uric Acid Levels in Oxonate-induced Rats

    Wen-Ling Wang, Shi-Yuan Sheu, Wen-Dar Huang, Ya-Ling Chuang, Han-Chun Tseng, Tzann-Shun Hwang, Yuan-Tsung Fu, Yueh-Hsiung Kuo, Chun-Hsu Yao, Tzong-Fu Kuo

    pp. S223–S227 · DOI: 10.4103/0973-1296.182171 · Published 11 May 2016

    Background: Tradescantia albiflora (TA) Kunth (Commelinaceae) has been used for treating gout and hyperuricemia as folklore remedies in Taiwan. Therefore, it is worthwhile to study the effect of TA extracts on lowering u…

  18. Article

    Life Span and Motility Effects of Ethanolic Extracts from Sophora moorcroftiana Seeds on Caenorhabditis elegans

    Xin Li, Junxian Han, Rongyan Zhu, Rongrong Cui, Xingming Ma, Kaizhong Dong

    pp. S228–S230 · DOI: 10.4103/0973-1296.182152 · Published 11 May 2016

    Background: Sophora moorcroftiana is an endemic shrub species with a great value in folk medicine in Tibet, China. In this study, relatively little is known about whether S. moorcroftiana is beneficial in animals’ nervou…

  19. Article

    Chemopreventive Agents from Physalis minima Function as Michael Reaction Acceptors

    Ruizhi Men, Ning Li, Chihong Ding, Yingzhan Tang, Yachao Xing, Wanjing Ding, Zhongjun Ma

    pp. S231–S236 · DOI: 10.4103/0973-1296.182153 · Published 11 May 2016

    Background: The fruits of some varieties of genus Physalis have been used as delicious fruits and functional food in the Northeast of China. Materials and Methods: To reveal the functional material basis, we performed bi…

  20. Article

    Preparation and Evaluation of Andrographolide Solid Dispersion Vectored by Silicon Dioxide

    Dingkun Zhang, Junzhi Lin, Fang Zhang, Xue Han, Li Han, Ming Yang, Wenquan Zou

    pp. S245–S252 · DOI: 10.4103/0973-1296.182156 · Published 11 May 2016

    Background: Andrographolide (Andro) is a “natural antibiotic” as well as a typical insoluble drug. The purpose of this study was to investigate the feasibility of commercially available silica (SiO2) as a carrier of soli…

  21. Article

    Simultaneous Determination of Eight Bioactive Compounds in Dianthus superbus by High‑performance Liquid Chromatography

    Bo-Ra Yun, Hye Jin Yang, Jin Bae Weon, Jiwoo Lee, Min Rye Eom, Choong Je Ma

    pp. S264–S269 · DOI: 10.4103/0973-1296.182159 · Published 11 May 2016

    Background: Dianthus superbus, one of traditional herbal medicine, is widely used to treat urethritis, carbuncles and carcinoma. Objective: A simultaneous determination method was established for controlling the quality …

  22. Article

    Quantitative Analysis and Comparison of Four Major Flavonol Glycosides in the Leaves of Toona sinensis (A. Juss.) Roemer (Chinese Toon) from Various Origins by High‑Performance Liquid Chromatography‑Diode Array Detector and Hierarchical Clustering Analysis

    Xiaoxiang Sun, Liting Zhang, Yaqi Cao, Qinying Gu, Huan Yang, James P. Tam

    pp. S270–S276 · DOI: 10.4103/0973-1296.182160 · Published 11 May 2016

    Background: Toona sinensis (A. Juss.) Roemer is an endemic species of Toona genus native to Asian area. Its dried leaves are applied in the treatment of many diseases; however, few investigations have been reported for t…

  23. Article

    Chromatographic and Spectrophotometric Analysis of Phenolic Compounds from Fruits of Libidibia ferrea Martius

    Magda R. A. Ferreira, Mônica T. M. Fernandes, Wliana A. V. da Silva, Isabelle C. F. Bezerra, Tatiane P. de Souza, Maria F. Pimentel, Luiz A. L. Soares

    pp. S285–S291 · DOI: 10.4103/0973-1296.182165 · Published 11 May 2016

    Background: Libidibia ferrea (Mart. ex Tul.) L.P. Queiroz (Fabaceae) is a tree which is native to Brazil, widely known as “Jucá,” where its herbal derivatives are used in folk medicine with several therapeutic properties…

  24. Article

    A New Sucrase Enzyme Inhibitor from Azadirachta indica

    Mohamed I. S. Abdelhady, Usama Shaheen, Ammar Bader, Mahmoud A. Youns

    pp. S293–S296 · DOI: 10.4103/0973-1296.185705 · Published 7 July 2016

    Background: Sucrase enzyme inhibitor considered as an oral anti-diabetic therapy that delays the absorption of eaten carbohydrates, reducing the postprandial glucose and insulin peaks to reach normoglycemia. Materials an…

  25. Article

    Storing of Extracts in Polypropylene Microcentrifuge Tubes Yields Contaminant Peak During Ultra-flow Liquid Chromatographic Analysis

    Parthraj R. Kshirsagar, Harsha Hegde, Sandeep R. Pai

    pp. S303–S306 · DOI: 10.4103/0973-1296.185719 · Published 7 July 2016

    Aim: This study was designed to understand the effect of storage in polypropylene microcentrifuge tubes and glass vials during ultra- flow liquid chromatographic (UFLC) analysis. Materials and Methods: One ml of methanol…

  26. Article

    Isolation and Structure Determination of 24-Methylenecycloartanyl Ferulate from Indian Rice Bran and Its Quantitative Analysis

    Amol P. Muthal, Supada R. Rojatkar, Subhash Laxmanrao Bodhankar

    pp. S307–S314 · DOI: 10.4103/0973-1296.185722 · Published 7 July 2016

    Background: γ‑oryzanol is a major bioactive constituent in rice. Most of the literature reports isolation of 24‑methylenecycloartanyl ferulate (24‑mCAF) from rice bran oil (RBO) of other than Indian variety. Current rese…

  27. Article

    Elicitation Based Enhancement of Secondary Metabolites in Rauwolfia serpentina and Solanum khasianum Hairy Root Cultures

    Mrinalini Srivastava, Swati Sharma, Pratibha Misra

    pp. S315–S320 · DOI: 10.4103/0973-1296.185726 · Published 7 July 2016

    Background: Rauwolfia serpentina and Solanum khasianum are well‑known medicinally important plants contained important alkaloids in their different parts. Elicitation of these alkaloids is important because of associated…

  28. Article

    Catha edulis Extract Induces H9c2 Cell Apoptosis by Increasing Reactive Oxygen Species Generation and Activation of Mitochondrial Proteins

    Syam Mohan, Siddig Ibrahim Abdelwahab, Yahya Hasan Hobani, Suvitha Syam, Adel S. Al‑Zubairi, Rashad Al‑Sanousi, Magbool Essa Oraiby

    pp. S321–S326 · DOI: 10.4103/0973-1296.185732 · Published 7 July 2016

    Background: Catha edulis (Khat) is an evergreen shrub or small tree, traditionally used by various peoples of the Arabian Peninsula and Africa as an integral component of the socioeconomic traditions. It is believed that…

  29. Article

    Purified Essential Oil from Ocimum sanctum Linn. Triggers the Apoptotic Mechanism in Human Breast Cancer Cells

    Thamilvaani Manaharan, Ramaraj Thirugnanasampandan, Rajarajeswaran Jayakumar, M. S. Kanthimathi, Gunasekar Ramya, Madhusudhanan Gogul Ramnath

    pp. S327–S331 · DOI: 10.4103/0973-1296.185738 · Published 7 July 2016

    Background: Essential oil of Ocimum sanctum Linn. exhibited various pharmacological activities including antifungal and antimicrobial activities. In this study, we analyzed the anticancer and apoptosis mechanisms of Ocim…

  30. Article

    A New Octadecenoic Acid Derivative from Caesalpinia gilliesii Flowers with Potent Hepatoprotective Activity

    Samir M. Osman, Alaadin E. El-Haddad, Mohamed A. El-Raey, Soad M. Abd El-Khalik, Mahmoud A. Koheil, Michael Wink

    pp. S332–S336 · DOI: 10.4103/0973-1296.185752 · Published 7 July 2016

    Background: Caesalpinia gilliesii Hook is an ornamental shrub with showy yellow flowers. It was used in folk medicine due to its contents of different classes of secondary metabolites. In our previous study, dichlorometh…

  31. Article

    Protective Effects of Silymarin, Alone or in Combination with Chlorogenic Acid and/or Melatonin, Against Carbon Tetrachloride‑induced Hepatotoxicity

    Nouf Al‑Rasheed, Laila Faddah, Nawal Al‑Rasheed, Yieldez A. Bassiouni, Iman H. Hasan, Ayman M. Mahmoud, Raeesa A. Mohamad, Hazar I. Yacoub

    pp. S337–S345 · DOI: 10.4103/0973-1296.185765 · Published 7 July 2016

    Objective: The aim of this study was to evaluate the hepatoprotective effects of silymarin (SIL), alone and combined with chlorogenic acid (CA) and/or melatonin (ME), using a rat model of carbon tetrachloride (CCl4)‑indu…

  32. Article

    New Abietane Diterpenes from Euphorbia Pseudocactus Berger (Euphorbiaceae) and Their Antimicrobial Activity

    Azza Ramy Abdel‑Monem, Enas Hussein Abdelrahman

    pp. S346–S349 · DOI: 10.4103/0973-1296.185768 · Published 7 July 2016

    Background: Euphorbia is the largest genus in Euphorbiaceae. Terpenoids were isolated from most species of this genus. Objective: Since no previous study was reported about Euphorbia pseudocactus Berger, we started here …

  33. Article

    Cocculus hirsutus: Molecular Docking to Identify Suitable Targets for Hepatocellular Carcinoma by In silico Technique

    B. Samuel Thavamani, Molly Mathew, S. P. Dhanabal

    pp. S350–S352 · DOI: 10.4103/0973-1296.185769 · Published 7 July 2016

    Background: Protein–ligand interaction plays a major role in identification of the possible mechanism by which a ligand can bind with the target and exerts the pharmacological action. Objective: The aim is to identify th…

  34. Article

    Assessment of the Polyphenolic Content, Free Radical Scavenging, Anti‑inflammatory, and Antimicrobial Activities of Acetone and Aqueous Extracts of Lippia javanica (Burm.F.) Spreng

    Abiola M. Asowata‑Ayodele, Gloria A. Otunola, Anthony J. Afolayan

    pp. S353–S362 · DOI: 10.4103/0973-1296.185770 · Published 7 July 2016

    Background: Lippia javanica (Burm.F.) Spreng is one of the spice plants commonly found in almost every part of South Africa. Apart from its culinary uses, it is also traditionally used as an insect repellant and infusion…

  35. Article

    Potency of Massoia Bark in Combating Immunosuppressed‑related Infection

    Triana Hertiani, Sylvia Utami Tunjung Pratiwi, Agustinus Yuswanto, Prisci Permanasari

    pp. S363–S370 · DOI: 10.4103/0973-1296.185771 · Published 7 July 2016

    Background: As part of our search for new potential natural resources to eradicate infection, we have revealed the prominent potency of massoia bark (Massoia aromatica Becc, Lauraceae) in combating immunosuppressed‑relat…

  36. Article

    The Antioxidant Potential of Azadirachta indica Ameliorates Cardioprotection Following Diabetic Mellitus‑Induced Microangiopathy

    Naveen Kumar Gupta, Nidhi Srivastva, Parvesh Bubber, Sanjeev Puri

    pp. S371–S378 · DOI: 10.4103/0973-1296.185772 · Published 7 July 2016

    Background: Cardiac complications associated with diabetes mellitus have become major cause of concern. Antidiabetic drugs, with varied mode of action, are although available, apprehensions exist for their limited action…

  37. Article

    DNA‑based Simultaneous Identification of Three Terminalia Species Targeting Adulteration

    Sonal Sharma, Neeta Shrivastava

    pp. S379–S383 · DOI: 10.4103/0973-1296.185776 · Published 7 July 2016

    Background: Various parts of three Terminalia species, namely, Terminalia arjuna (stem bark), Terminalia bellirica (fruit), and Terminalia chebula (fruit) are widely known for their therapeutic principles and other comme…

  38. Article

    Efficiency of matK, rbcL, trnH-psbA, and trnL-F (cpDNA) to Molecularly Authenticate Philippine Ethnomedicinal Apocynaceae Through DNA Barcoding

    Vincent Louie Domingo Cabelin, Grecebio Jonathan Duran Alejandro

    pp. S384–S388 · DOI: 10.4103/0973-1296.185780 · Published 7 July 2016

    Background: The Philippines is home to some ethnomedicinal Apocynaceae that has been used to cure common ailments. They are perceived to be safe, but misidentification can lead to substitution and adulteration. Morpholog…

ORIGINAL ARTICLE

  1. Article

    Kinetics of Inhibition of Monoamine Oxidase Using Curcumin and Ellagic Acid

    Dharmendra Kumar Khatri, Archana Ramesh Juvekar

    pp. S116–20 · DOI: 10.4103/0973-1296.182168 · Published 11 May 2016

    Background: Curcumin and ellagic are the natural polyphenols having a wide range of pharmacological actions. They have been reported to have their use in various neurological disorders. Objective: This study was aimed to…

  2. Article

    Pharmacognostic Screening of Piper trichostachyon Fruits and its Comparative Analysis with Piper nigrum Using Chromatographic Techniques

    Vinayak Upadhya, Sandeep R. Pai, Gireesh M. Ankad, Harsha V. Hegde

    pp. S152–8 · DOI: 10.4103/0973-1296.182172 · Published 11 May 2016

    Background: Piper trichostachyon is a wild, endemic Piper species from Western Ghats of India. The folklore healers of Belagavi region use this plant, similar to Piper nigrum. Aims: The present study investigates the com…

  3. Article

    Quercetin Suppresses the Migration and Invasion in Human Colon Cancer Caco‑2 Cells Through Regulating Toll‑like Receptor 4/Nuclear Factor‑kappa B Pathway

    Mingyang Han, Yucheng Song, Xuedong Zhang

    pp. S237–44 · DOI: 10.4103/0973-1296.182154 · Published 11 May 2016

    Objective: The migration and invasion features, which were associated with inflammatory response, acted as vital roles in the development of colon cancer. Quercetin, a bioflavonoid compound, was widely spread in vegetabl…

  4. Article

    Total Alkaloids of Sophora alopecuroides Inhibit Growth and Induce Apoptosis in Human Cervical Tumor HeLa Cells In vitro

    Jian-Guang Li, Xiao-Yi Yang, Wei Huang

    pp. S253–6 · DOI: 10.4103/0973-1296.182157 · Published 11 May 2016

    Background: Uygur females of Xinjiang have the higher incidence of cervical tumor in the country. Alkaloids are the major active ingredients in Sophora alopecuroides, and its antitumor effect was recognized by the medica…

  5. Article

    The Inhibitory Effect of Rhein on Proliferation of High Glucose-induced Mesangial Cell Through Cell Cycle Regulation and Induction of Cell Apoptosis

    Shouzhu Xu, Yanying Lv, Jing Zhao, Junping Wang, Guangjian Wang, Siwang Wang

    pp. S257–63 · DOI: 10.4103/0973-1296.182158 · Published 11 May 2016

    Objectives: Increased mesangial cell proliferation and accumulation of extracellular matrix (ECM) are the major pathological features of early‑stage diabetic nephropathy. This study was sought to investigate the inhibito…

  6. Article

    Optimization Extraction Process of Polysaccharides from Suillus granulatus and Their Antioxidant and Immunological Activities In vitro

    Feng Zhou, Song Yan, Shuang Chen, Liying Gong, Tingting Su, Zhanyong Wang

    pp. S277–84 · DOI: 10.4103/0973-1296.182161 · Published 11 May 2016

    Background: Suillus granulatus is an edible and medicinal fungus in China. S. granulatus polysaccharide (SGP) was considered as the main bioactivity compounds in S. granulatus. Therefore, the extraction of SGP and their …

  7. Article

    Screening of Chonemorpha fragrans Bioactive Extracts for Cytotoxicity Potential and Inhibition Studies of Key Enzymes Involved in Replication

    Pradnya Prakash Kedari, Nutan Padmanabh Malpathak

    pp. S297–302 · DOI: 10.4103/0973-1296.185708 · Published 7 July 2016

    Background: Chonemorpha fragrans (Moon) Alston, a liana belonging to family Apocynaceae, is used in traditional medicinal systems for the treatment of various ailments. It is an unexplored medicinal plant with respect to…