Volume 15, Issue 61

6 March 2019 · pp. 177–361 · 25 articles

Volume: 15
Issue: 61
Published: 6 March 2019
Pages: 177–361
Articles: 25
Sections: 1
ISSN: Print - 0973-1296, Online - 0976-4062
Journal: PM

Original Article

In this issue

Original Article

Article
Quality Assessment of Pollen Typhae by High‑performance Liquid Chromatography Fingerprint, Hierarchical Cluster Analysis, and Principal Component Analysis
Xin Ma, Haimiao Zou, Yibin Pan, Jing Su, Yujiao Qiu, Mingfeng Qiu
pp. 177–182 · DOI: 10.4103/pm.pm_469_18 · Published 6 March 2019
Aim: This study aims to establish the quality assessment methods of Pollen Typhae. Materials and Methods: High performance liquid chromatography (HPLC) fingerprint analysis, hierarchical cluster analysis (HCA), and princ…
Article
Chamuangone‑Enriched Garcinia cowa Leaf Extract with Rice Bran Oil: Extraction and Cytotoxic Activity against Cancer Cells
Pirunrat Sae‑Lim, Supreeya Yuenyongsawad, Pharkphoom Panichayupakaranant
pp. 183–188 · DOI: 10.4103/pm.pm_472_18 · Published 6 March 2019
Objectives: Some vegetable oils were determined as an alternative green solvent for extraction of an anticancer compound, chamuangone from G. cowa leaf. The chamuangone‑enriched extract was standardized and evaluated for…
Article
Impact of Ginsenoside‑Rg3 on Catecholamine Secretion in the Perfused Model of the Rat Adrenal Medullae
Ki‑Hwan Kim, Hyo‑Jeong Lim, Young‑Jae Ki, Dong‑Yoon Lim
pp. 189–198 · DOI: 10.4103/pm.pm_200_18 · Published 6 March 2019
Background: The present study was the first attempt to explore the characteristics of ginsenoside-Rg3 (Rg3) on release of catecholamines (CA) in the perfused rat adrenal medullae and also to verify the underlying action …
Article
New Bioactive C15 Acetogenins from the Red Alga Laurencia obtusa
Mohamed A. Ghandourah, Walied M. Alarif, Nahed O. Bawakid
pp. 199–203 · DOI: 10.4103/pm.pm_298_18 · Published 6 March 2019
Objective: With regard to the uniqueness of the red algae of the genus Laurencia as the source of C15‑acetogenins, along with the diversity of biological applications; the acetogenin content of the Red Sea Laurencia obtu…
Article
Optimization of Infrared‑assisted Extraction of Bioactive Lactones from Saussurea lappa L. and their Effects against Gestational Diabetes
Karim Raafat, Nada El-Darra, Fatima A. Saleh, Hiba N. Rajha, Nicolas Louka
pp. 208–218 · DOI: 10.4103/pm.pm_380_18 · Published 6 March 2019
Objectives: The aim of the current study is to optimize an infrared‑assisted extraction (IR‑AE) method for S. lappa bioactive constituents, phytochemically investigate its content, isolate its most active constituent, an…
Article
Dictamnus dasycarpus Turcz., Root Bark Alleviates Oxazolone‑Induced Atopy‑Like Dermatitis in Mice
Beodeul Yang, Ji Hyo Lyu, Sura Kim, Young Chul Park, Koanhoi Kim, Hyungwoo Kim
pp. 219–225 · DOI: 10.4103/pm.pm_110_18 · Published 6 March 2019
Objective: We investigated the anti‑inflammatory effects of D. dasycarpus extract (DDE) using a mouse model with atopic dermatitis (AD)‑like dermatitis. Materials and Methods: The therapeutic effects of DDE on skin lesio…
Article
Antidepressant‑Like Effects of Methanol Extract and Fractions of Hypericum juniperinum Kunth in the Forced Swimming Test
Laura A. Mejía-Agudelo, Maritza A. Rojas, Mario F. Guerrero-Pabón, Freddy A. Ramos, Leonardo Castellanos
pp. 226–231 · DOI: 10.4103/pm.pm_341_18 · Published 6 March 2019
Objective: The aim of this study was to evaluate the antidepressant‑like effects of a methanol extract, as well as ethyl acetate and butanol fractions, obtained from aerial parts of Hypericum juniperinum K. Materials and…
Article
Biological Evaluation and Molecular Docking Study of Metabolites from Salvadora persica L. Growing in Egypt
Mohammed M. Ghoneim, Wael M. Afifi, Mohamed Ibrahim, Mohamed Elagawany, Maan T. Khayat, Mohamed H. Aboutaleb, Ahmed M. Metwaly
pp. 232–237 · DOI: 10.4103/pm.pm_361_18 · Published 6 March 2019
Objective: Exploring the anti-MRSA activity of S. persica L. metabolites and its mechanism of action on a molecular level. Materials and Methods: Structure elucidation of the isolated metabolites was carried out by spect…
Article
Ameliorative Effects of Tannic Acid on Lipopolysaccharide‑induced Sepsis and Acute Lung Injury in Mice
Ruirui Zhang, Minyan Dang, Shoutian Qiu, Hongyan Gu, Pingping He, Gang Guo, Tao Zhang
pp. 238–243 · DOI: 10.4103/pm.pm_364_18 · Published 6 March 2019
Background: Acute lung injury (ALI) caused by endotoxins is a severe complication causing lethal conditions. Prevention of the inflammatory response is necessary to overcome this condition. Tannic acid is a polyphenol kn…
Article
Ameliorative Effect of Sargassum fusiforme Polysaccharides on Oxidative Stress and Inflammation in Ethanol‑induced Gastric Ulcer
Gangwu Sun, Tao Lian, Bin Yang, Yi Gu, Xiaojia Li
pp. 244–252 · DOI: 10.4103/pm.pm_457_18 · Published 6 March 2019
Background: Gastric ulcer is also known as stomach ulcer which is complex with multifactor‑associated disease and shows high prevalent worldwide. It affects most of the people around the world, and the initiation and pro…
Article
Antioxidant and Anti‑caspase‑3 Activity of Chitosan‑Pinus merkusii Extract Nanoparticle on Lead Acetate‑induced Hepatotoxicity
Sri Agus Sudjarwo, Giftania Wardani, Koerniasari Eraiko, Koerniasari Koerniasari
pp. 253–258 · DOI: 10.4103/pm.pm_393_18 · Published 6 March 2019
Objective: In the present study, we investigated the impact of Chitosan‑P. merkusii extract nanoparticle against lead acetate‑induced hepatotoxicity in rats. Materials and Methods: Chitosan‑P. merkusii extract nanopartic…
Article
Gracilaria foliifera (Forssk.) Børgesen Ethanolic Extract Triggers
Apoptosis via Activation of p53 Expression in HepG2 Cells Sasikumar Shebi, Devaraj Ezhilarasan, John Thomas, Natarajan Chandrasekaran, Amitava Mukherjee
pp. 259–263 · DOI: 10.4103/pm.pm_379_18 · Published 6 March 2019
Objective: To investigate the cytotoxic potentials of G. foliifera in HepG2 cells. Materials and Methods: HepG2 cells were fed with culture medium supplemented with different concentrations of ethanolic extract of G. fol…
Article
Pharmacokinetic Study of Hepatoprotective Coumarinolignoids from Cleome viscosa in Mice Using Validated High‑Performance Liquid Chromatography‑Photodiode Array Method
Kuldeep Singh Yadav, Ranjana Ranjana, Sudeep Tandon, Narayan Prasad Yadav, Karuna Shanker
pp. 270–276 · DOI: 10.4103/pm.pm_508_18 · Published 6 March 2019
Objectives: However, the bioavailability and pharmacokinetics of Cliv‑92 are still not clear. The present study is the first validated method which deals with the assay of Cliv‑92 in mouse plasma. Methods: Single‑step sa…
Article
Antiproliferative and Antiangiogenic Effects of Zerumbone from Zingiber zerumbet L. Smith in Sprague Dawley Rat Model of Hepatocellular Carcinoma
Nozlena Abdul Samad, Ahmad Bustamam Abdul, Heshu Sulaiman Rahman, Rasedee Abdullah, Tengku Azmi Tengku Ibrahim, Hemn Hassan Othman
pp. 277–282 · DOI: 10.4103/pm.pm_118_18 · Published 6 March 2019
Aims: This study aimed to investigate the in vivo antiproliferative and antiangiogenesis effects of ZER using rats with diethylnitrosamine‑induced hepatocellular carcinoma (HCC). Materials and Methods: The antiproliferat…
Article
Hepatoprotective and Antioxidant Potential of Radish Seed Aqueous Extract on Cadmium‑induced Hepatotoxicity and Oxidative Stress in Mice
Qingfeng He, Yunjing Luo, Pingping Zhang, Chengsong An, Ailin Zhang, Xiaodan Li, Lingling You, Cuicui Liu
pp. 283–289 · DOI: 10.4103/pm.pm_365_18 · Published 6 March 2019
Objective: The research aimed to investigate the mitigation effect of RSE against Cd‑induced hepatotoxicity in experimental animals. Materials and Methods: The mice were administered intraperitoneally with Cd Chloride (C…
Article
Ameliorating Effects of Geranium koreanum Kom on Esophageal Damage in Reflux Esophagitis via Nuclear Factor‑κB Signaling‑Mediated Anti‑Inflammatory Activities
Hyeon Hwa Nam, Li Nan, Byung Kil Choo
pp. 290–297 · DOI: 10.4103/pm.pm_367_18 · Published 6 March 2019
Objective: In the present study, we wanted to demonstrate the anti‑inflammatory effects of G. koreanum extracts on esophagus damage in acute reflux esophagitis (RE)‑induced rats. Materials and Methods: The anti‑inflammat…
Article
Effect of Gardenia/Acanthopanax‑Medicated Serum on High Level Corticosterone‑induced Pheochromocytoma Cell Apoptosis and Calcium Ion Concentration
Xiang‑Dong Xu, Xiang‑Qing Xu, Hong Yun Wu, Zhi Jun Li
pp. 298–303 · DOI: 10.4103/pm.pm_273_18 · Published 6 March 2019
Objective: This study aims to investigate the effect of gardenia/ acanthopanax‑medicated serum on pheochromocytoma (PC12) cell apoptosis and calcium ion concentration, and explore the antidepression mechanism of gardenia…
Article
Drug interaction between Shoseiryuto Extract or Catechins and Fexofenadine through Organic‑Anion‑transporting Polypeptide 1A2 In vitro
Katsuhiko Masumoto, Zhiyang Quan, Kan’ichiro Ishiuchi, Takashi Matsumoto, Junko Watanabe, Toshiaki Makino
pp. 304–308 · DOI: 10.4103/pm.pm_386_18 · Published 6 March 2019
Objective: Fexofenadine is an anti‑allergy drug frequently used to treat rhinitis, which is absorbed through organic‑anion‑transporting polypeptide (OATP) 1A2 in the intestine. Clinical studies have revealed that grapefr…
Article
Neuroprotective Potential of Methanolic Extract of Saraca asoca Bark against Doxorubicin‑Induced Neurotoxicity
Sri Pragnya Cheruku, Mallikarjuna Rao Chamallamudi, Grandhi Venkata Ramalingayya, Subhankar Biswas, Karthik Gourishetti, Krishnadas Nandakumar, Raviraj Devkar, Sanchari Basu Mallik, Madhavan Nampoothiri
pp. 309–316 · DOI: 10.4103/pm.pm_79_18 · Published 6 March 2019
Aim: The present study was designed to assess the neuroprotective potential of Saraca asoca bark against Dox‑induced neurotoxicity, considering its previously reported anticlastogenic effect. Materials and Methods: Metha…
Article
Anti‑Inflammatory Activity of Corylopsis coreana Uyeki Extracts and Isolated Compounds by Inhibiting Nitric Oxide and Cytokine Production
Jun Yin, HyeSoo Wang, MinWon Lee
pp. 317–321 · DOI: 10.4103/pm.pm_144_18 · Published 6 March 2019
Aims: To study the anti‑inflammatory effects of C. coreana Uyeki leaf and bark extracts as well as their major active compounds, we evaluated in vitro levels of tumor necrosis factor‑α (TNF‑α), interleukin‑6 (IL‑6), and …
Article
Antinociceptive Activity of the Peptide Fraction from the Venom of Social Wasp Pseudopolybia vespiceps Testacea
Lilian Carneiro Dos Anjos, Jacqueline Coimbra Gonçalves, Bruna Ramos De Araujo, Marcia Renata Mortari
pp. 322–326 · DOI: 10.4103/pm.pm_238_18 · Published 6 March 2019
Background: The genus <em>Crotalaria</em> (Fabaceae) is known for its diverse pharmacological activities. Objective: The present study was aimed to evaluate the anti-inflammatory and antioxidant activities of <em>Crotala…
Article
Cucurbita argyrosperma Seed Extract Ameliorating Oxidative Stress in H9c2 Cardiomyocytes through Suppression of Intracellular Reactive Oxygen Species Production
Rosa Martha Perez-Gutierrez, Maria Fernanda Estrella-Mendoza, Javier Flores Estrada, Rebeca Lopez Marure
pp. 327–334 · DOI: 10.4103/pm.pm_432_18 · Published 6 March 2019
Background: Oxidative stress induced by the excessive reactive oxygen species (ROS) generation is involved in the pathogenesis of various diseases. Methanol extract from Cucurbita argyrosperma (CM) was used to test for a…
Article
Protective Effects of Genistein Alleviate Alcohol-Induced Liver Injury in Rats
Wanlapa Leelananthakul, Duangporn Werawatganon, Naruemon Klaikeaw, Maneerat Chayanupatkul
pp. 342–347 · DOI: 10.4103/pm.pm_530_18 · Published 6 March 2019
Article
Determination of Three Active Components in Euphorbia humifusa Willd. Using High‑performance Liquid Chromatography with Diode‑array Detection and Autophagy and Apoptosis Analysis of Normal Rat Kidney and HeLa Cells
Shuge Tian, E. Wen, Na Mi, Hui Li
pp. 348–355 · DOI: 10.4103/pm.pm_348_18 · Published 6 March 2019
Objective: To evaluate the anticervical cancer activity of EH and its main active ingredient Gallic acid (GA) by studying on autophagy and apoptosis of normal rat kidney (NRK) and HeLa cell lines, respectively. Materials…
Article
Photoprotective Activity of Medicinal Plants From the Caatinga Used as Anti-inflammatories
Bruno de Almeida Andrade, Allan Jonathan Chernichiarro Corrêa, Ana Klarissa Soares Gomes, Patrícia Maria da Silva Neri, Tadeu José da Silva Peixoto Sobrinho, Thiago Antônio de Sousa Araújo, Valerium Thijan Nobre de Almeida e Castro, Elba Lúcia Cavalcanti de Amorim
pp. 356–361 · DOI: 10.4103/pm.pm_482_18 · Published 6 March 2019
Objective: The present study aims to determine the in vitro sun protection factor (SPF) of 15 species from the Caatinga region used in popular medicine as anti‑inflammatories. Materials and Methods: Samples of duly ident…