Volume 53, Issue 2

Tomasz Kowalski, Agnieszka Skowron, Michał Nowakowski

pp. 186–191 · DOI: 10.5530/ijper.53.2.24 · 2019

Background: Objective structured practical examination (OSPE) is a new concept that allows students to assess their practical skills. These are multifunctional assessment tools that can be used to test a wide range of st…

Gaurav Tiwari, Ruchi Tiwari, Pranay Wal

pp. 192–201 · DOI: 10.5530/ijper.53.2.25 · 2019

Background: Cutting-edge issues for nanomedicine involve knowledge of the problems associated with toxicity and environmental effect of nanoscale substances (substances whose structure is on the dimensions of nanometers,…

Reddy Vobbineni Lokesh, Adusumilli Pramod K, Bhushan Shashi, Vivekandan Kalaiselvan, Singh Gyanendra Nath

pp. 202–207 · DOI: 10.5530/ijper.53.2.26 · 2019

Aim: Pharmacy Council of India (PCI) and the All India Council for Technical Education (AICTE) are the two professional organizations which are presently regulating the pharmacy education in India. Curriculum change of p…

Yanli Yang, Jie Zhong, Enzhong Li

pp. 208–211 · DOI: 10.5530/ijper.53.2.27 · 2019

Aim: An experimental teaching and learning program used in biochemistry and molecular biology with first-year students in the second term in the Faculty of Biological Sciences at Huanghuai University, China. Materials: S…

Karunrat Tewthanom

pp. 212–215 · DOI: 10.5530/ijper.53.2.28 · 2019

Background: Kahoot is a web-based learning that uses worldwide in the education field. From the review literature, lecture with a Kahoot web-based learning will improve the learning skill. However, there have been a few …

Velenti Chauhan, Vimal Patel, Bhavesh Akbari, Rohan Barse

pp. 216–224 · DOI: 10.5530/ijper.53.2.29 · 2019

Aim: Goserelin acetate is parenterally administered, a typical LHRH analogue for the treatment of prostate cancer. The objective of present work was to formulate and evaluate long acting in situ forming microparticles of…

Chaudhari Praveen, Desai Ujwala

pp. 225–235 · DOI: 10.5530/ijper.53.2.30 · 2019

Introduction: Our main purpose of present study was to find out the effect of different crosslinking agents along with its concentration during polymer synthesis and to find the most suitable polymer for ocular drug deli…

Wu Jian, Li Wen-lan, Xu Ying, Liu Ying-jie, Liu Ri-jia, Yu Miao

pp. 236–241 · DOI: 10.5530/ijper.53.2.31 · 2019

Aim: This study aims to develop a highly sensitive and specific UPLC-MS/MS method to explore the pharmacokinetic properties of three representative active alkaloids (benzoylhypaconine, benzoylmesaconine, benzoylaconine) …

Joydeep Paul, Mohammad Nasiruddin, Irfan Ahmad Khan, Rahat Ali Khan, Sayeedul Hasan Arif

pp. 242–249 · DOI: 10.5530/ijper.53.2.32 · 2019

Objectives: Tuberculosis is one the most prevalent microbial diseases worldwide and hepatotoxicity is one of the major side effects of first line anti-tubercular drug, Isoniazid. The reported pharmacological activities o…

Taofik Olatunde Sunmonu, Francis Bayo Lewu

pp. 250–260 · DOI: 10.5530/ijper.53.2.33 · 2019

Background: Diabetes is one of the most common metabolic disorders worldwide and the disease is generally believed to be incurable. However, the historical success of natural products as therapeutic agents has led to the…

Hajira Banu Haroon, Anita Murali

pp. 261–267 · DOI: 10.5530/ijper.53.2.34 · 2019

Aim: The aim of this study was to investigate the aldose reductase inhibition and anti-cataract property of W. volubilis root extract in rats with streptozotocin induced diabetes mellitus. Methods: Diabetes was induced b…

Salih Ökten, Makbule Ekiz, Ahmet Tutar, Burcu Bütün, Ümit Muhammet Koçyiğit, Gülaçtı Topçu, İlhami Gülçin

pp. 268–275 · DOI: 10.5530/ijper.53.2.35 · 2019

Background: The inhibition of both hydrolysis products of acetylcholine (ACh), Acetylcholinesterase (AChE) and Butyrylcholinesterase (BChE), is essential for successful treatment of Alzhemier patients. Objectives: This s…

Devika Bhai Rajamma, Girija Chamarahalli Ramakrishna Iyer, Inamul Hasan Madar, Prashantha Karunakar

pp. 276–285 · DOI: 10.5530/ijper.53.2.36 · 2019

Introduction: Investigations on Schiff bases are one of the current pharmaceutical research trends due to their broad-spectrum biological activities and unique structural features such as intramolecular hydrogen bond for…

Naresh Panigrahi, Swastika Ganguly, Jagadeesh Panda

pp. 286–300 · DOI: 10.5530/ijper.53.2.37 · 2019

Objective: The main objective of our present study, is to potentiate the antibacterial activity of biphenyl chalcones and oxazolidinones, thus in order to achieve the potent antibacterial agents, we coupled both derivati…

Prajakta Deepak Kapadnis, Shilpa Nilesh Shrotriya

pp. 301–309 · DOI: 10.5530/ijper.53.2.38 · 2019

Aim/ Background:Wounds are considered as a common health problem due to their considerable burden on social life. Polymeric nanofibers have attracted attention in wound dressings due to their large surface area, smaller …

Prasanthi Thayi, Lakshman Rao Atmakuri, Nandini Mandada, Hemanth Mandava, Bhuvaneswari Mandru, Chaitanya Manne

pp. 310–315 · DOI: 10.5530/ijper.53.2.39 · 2019

Aim: A simple, sensitive, accurate and precise RP-HPLC method was developed for the determination of Dothiepin HCl (DTH) in pure and tablet dosage form. Methods: The method was developed by using Phenomenex C18 (250 X 4.…

Powar Trupti Ashok, Hajare Ashok Ananda

pp. 316–324 · DOI: 10.5530/ijper.53.2.40 · 2019

Aim and Objective: The objective of this work was to develop and validate a high performance liquid chromatography (HPLC) method for the quantitative analysis of melphalan, an anticancer drug from lyophilized nanosuspens…

Shih-Wei Lai, Cheng-Li Lin, Kuan-Fu Liao

pp. 325–329 · DOI: 10.5530/ijper.53.2.41 · 2019

Objectives: This study’s aim was to investigate whether selective serotonin reuptake inhibitors use was associated with the risk of colorectal cancer. Methods: From the claims data of Taiwan National Health Insurance Pro…

Yong Wang, Fei Deng

pp. 330–333 · DOI: 10.5530/ijper.53.2.42 · 2019

Objective:This study aimed to discuss the clinical effects of pantoprazole and octreotide in upper gastrointestinal hemorrhage. Methods: A total of 114 patients with upper gastrointestinal hemorrhage admitted in our hosp…

Zorica Terzic-Supic, Dragica Bukumiric, Milena Santric-Milicevic, Aleksandar Corac, Milica Paut Kusturica, Momcilo Mirkovic, Zoran Bukumiric, Jovana Todorovic, Biljana Ristic, Goran Trajkovic

pp. 334–342 · DOI: 10.5530/ijper.53.2.43 · 2019

Background: The objective of this study was to examine the knowledge and practices regarding expired medications and to identify their potential predictors. Methods: A cross-sectional study was conducted, between August …