Volume 55, Issue 2S

2021 · pp. 414–0 · 32 articles

Volume: 55
Issue: 2S
Published: 2021
Pages: 414–0
Articles: 32
Sections: 3
ISSN: Online - 0019-5464
Journal: IJPER

Review Article Original Article Analysis

In this issue

Review Article

Review
Solid Dispersion as a Technical Solution to Boost the Dissolution Rate and Bioavailability of Poorly Water-Soluble Drugs
Mohamed Salah Attia, Azza Ali Hasan, Fakhr-Eldin Soliman Ghazy, Eman Gomaa
pp. s327–s339 · DOI: 10.5530/ijper.55.2s.103 · Published 2021
Solid dispersion (SD) is one of the oldest and widely utilized techniques to improve the solubility of slowly dissolving drugs. A variety of pharmaceutically compatible additives using different emerging technology is us…
Review
Prescription: A Situation Analysis in Indian Health Care System
Sathish Venkatasamy Dhayalan, Arulkumaran G, Shalini Sivadasan
pp. s340–s344 · DOI: 10.5530/ijper.55.2s.104 · Published 2021
A prescription is the vital written communication from physician to patient, which consist of instruction to pharmacist on dispensing of drug regimen. Prescription writing is a critical task that suggests prescriber’s re…
Review
Medicinal and Nutritional Wonders of Miracle Moringa oleifera Lam.: Another Look
Raji Sundararajan, Edet Love Mendie, Lakshya Mittal, Gowrisree Varadarajan, Ignacio G Camarillo, Hemalatha Srinivasan
pp. s345–s352 · DOI: 10.5530/ijper.55.2s.105 · Published 2021
Background: Frequently described by Bogar and other greatest sithars, Moringa oleifera Lam (Moringa was derived from the Tamil word murungai)), is popular for its medicinal and nutritional values and benefits. Rich with …
Review
Comparison and Compilation of the Vaccine Approval Process of the United States of America and the European Union: A Road Map for the Emerging and Developing Countries in COVID-19 Crisis
Sumana Dosemane Radhakrishna, Ravi Gundadka Shriram, Shenaz Z. Khaleeli, Pankaj Dawar, Megha Chellath Kottayi, Akhilesh Dubey
pp. s353–s363 · DOI: 10.5530/ijper.55.2s.106 · Published 2021
Background: Vaccines are the-omit complex biological preparations that are meant to be used as a treatment or preventive measures against any specific disease condition. Vaccine research and development is a tedious, tim…

Original Article

Article
Impact of International Accreditation in Pharmacy Education: Pharmacy School Students’ Perspective
Rula Darwish, Mohammad Saleh, Khawlah Ammar, Mohammad AlMasri
pp. s364–s372 · DOI: 10.5530/ijper.55.2s.107 · Published 2021
Background: The accreditation of undergraduate Pharmacy Schools is an important quality assurance process. In spite of the widespread adoption of international accreditation processes and an increasing attention on accre…
Article
Transformation of Teachers to Mentors: Prerequisite of Time is to Excel Innovative Practices in Academics
Neelesh Malviya, Sapna Malviya, Rajiv Saxena, Manisha Dhere
pp. s373–s378 · DOI: 10.5530/ijper.55.2s.108 · Published 2021
The perception of Mentoring is definitely not new; indeed, it comes from a character named “Mentor” in Homer’s Odyssey. He was a trusted mentor to Odysseus’ son. The recent studies and Figures have given rise to prospero…
Article
Role of Learning Approach in Determining Learning Outcome During Active and Passive Learning Sessions in Pharmacology
Vimala Ananthy, Suresh Narayanan, Arthi Asokan
pp. s379–s384 · DOI: 10.5530/ijper.55.2s.109 · Published 2021
Objectives: The objective of the study is to estimate the difference in knowledge gain between the students of varied learning approaches during didactic lectures and concept mapping lectures. Materials and Methods: The …
Article
Preparation and Characterization of Chitosan Silicate Conjugate: It’s Role as a Super Disintegrant in Orally Fast Dissolving Films
Satheesha Babu Birur Kotappa, Podamala Rama Smriti
pp. s385–s395 · DOI: 10.5530/ijper.55.2s.110 · Published 2021
Aim: The aims of the present research work was to prepare and characterize the chitosan silicate conjugate, conjugate was included in orally fast dissolving films of levo cetirizine di hydrochloride as a super disintegra…
Article
Datura stramonium Leaves Mucilage Aided Buccoadhesive Films of Aceclofenac using 32 Factorial Design with Design-Expert Software
Hindustan Abdul Ahad, Haranath Chinthaginjala, Manchikanti Sai Priyanka, Dasari Rahul Raghav, Madana Gowthami, Varam Naga Jyothi
pp. s396–s404 · DOI: 10.5530/ijper.55.2s.111 · Published 2021
Aim and Objectives: The main motto of this work was to search the additive effect of Datura stramonium leaves mucilage in the making of buccoadhesive film by taking Aceclofenac as a model drug. Materials and Methods: Nin…
Article
Solubility Enhancement of Embelin by Complexation with Beta Cyclodextrin
Jashna K Kani, Elizabeth N Xavier
pp. s405–s413 · DOI: 10.5530/ijper.55.2s.112 · Published 2021
Introduction: Embelin, a phytoconstituent obtained from Embelia ribes of the Myrsinaceae family, has anti-cancer, anti-inflammatory, anti-bacterial, anti-fertility, analgesic, antidiabetic, anti-depressant and wound heal…
Article
Development of Colon Targeting Tablet of a JAK Inhibitor to Combat Chronic Ulcerative Colitis: A Novel Approach for Local Drug Delivery
Vakar Vakar, Rupa Mazumder, Swarupanjali Padhi, Kirpa Shanker Tiwari, Parikh Kinjal
pp. 414–s427 · DOI: 10.5530/ijper.55.2s.113 · Published 2021
Background: Tofacitinib, a pan-Janus kinase (JAK) inhibitor, initially used for the treatment of rheumatoid arthritis, was later found to have robust efficacy in Phase 2 and Phase 3 ulcerative colitis clinical trials. It…
Article
Curcumin Loaded Eudragit S100/PLGA Nanoparticles in Treatment of Colon Cancer: Formulation, Optimization, and in-vitro Cytotoxicity Study
Apeksha Saraf, Nidhi Dubey, Nitin Dubey, Mayank Sharma
pp. s428–s440 · DOI: 10.5530/ijper.55.2s.114 · Published 2021
Introduction: Polymeric nanoparticles provide a promising strategy for site-specific delivery of dietary phytochemicals in the treatment of colon cancer. Curcumin (CU) is a dietary phytochemical with well-proven anti-can…
Article
Polyacrylamide Grafted Gum Acacia (GA-g-PAM) Graft Copolymer as Efficient Polymeric Scaffold
Trishna Bal, Priyashi Singh, Aditya Dev Rajora, Sandeep Garg, Barnali Dasgupta Ghosh, Ashok Kumar Pattnaik
pp. s441–s447 · DOI: 10.5530/ijper.55.2s.115 · Published 2021
Background: Natural polysaccharides are mostly not stable in their original form but their biodegradable properties can be beneficial for use as polymeric scaffolds for tissue engineering. Microwave irradiation assisted …
Article
Proof-of-concept for Site-specific Delivery of Mesalamine Nanoparticles for Effective Therapy in Colitis
Nagaraja Sreeharsha, Rashmi Narayan, Joshi Vijaya, Anroop Nair
pp. s448–s456 · DOI: 10.5530/ijper.55.2s.116 · Published 2021
Background: Mesalamine loaded polymeric nanoparticles were prepared using three different polymers namely, Eudragit RS100, PLGA (50:50), or Eudragit RLPO, with an aim of targeted delivery to the inflamed colon. Materials…
Article
Protective Role of Caffeic Acid in Cognitive Dysfunction and Oxidative Stress Induced by Colchicine in Rats
Surubhotla Raviteja, Suman Manandhar, Keerthi Priya, Gangadhar Hari, K Sreedhara Ranganath Pai
pp. s457–s467 · DOI: 10.5530/ijper.55.2s.117 · Published 2021
Purpose: Alzheimer’s is a disease affecting mostly the Older population leading to the deterioration of cognitive capabilities. The protective effect of Caffeic acid in Colchicine-induced dementia was evaluated in the cu…
Article
Embelin and Levodopa Combination Therapy Mitigates Parkinson's Disease Complications in Mice
Anand Koppal, Senthilkumar Sivanesan, Vagdevi Hangarakatte Ramachandra, Ethirajan Sukumar, Rajagopalan Vijayaraghavan
pp. s468–s478 · DOI: 10.5530/ijper.55.2s.118 · Published 2021
Purpose: The present work evaluated the neuroprotective potential of embelin either alone and in combination with Levodopa in rotenone induced PD (Parkinson’s disease) model mice. Methods: Swiss albino male adult mice we…
Article
Effect of β-sitosterol on Insulin Receptor, Glucose Transporter 4 Protein Expression and Glucose Oxidation in the Gastrocnemius Muscle of High Fat Diet Induced Type -2 Diabetic Experimental Rats
Madhan Krishnan, Shyamaladevi Babu, Ponnulakshmi Rajagopal, Sohara Parveen Nazar, Mayilvanan Chinnaiyan, Selvaraj Jayaraman
pp. s479–s491 · DOI: 10.5530/ijper.55.2s.119 · Published 2021
Background: The newly available medications are ineffective because of their unintended side effects in the treatment of type 2 diabetes. Hence, search drugs, from plant sources. β-sitosterol is plant sterols with struct…
Article
An Agro-ecological Zoning Model Highlighting Potential Growing Areas for Medicinal Plants in Punjab
Preet Amol Singh, Anil Sood, Ashish Baldi
pp. s492–s500 · DOI: 10.5530/ijper.55.2s.120 · Published 2021
Background: The Ministry of AYUSH, Government of India has decided to emerge cultivation of medicinal plants as an attractive farming option due to a sharp increase in demand for medicinal plants. Punjab produces approxi…
Article
Evaluation of Antioxidant, Immunomodulatory and Anticancer Properties of Methanolic Extract of Neolamarckia cadamba Linn. Fruits
Amrita Chatterjee, Neelima Sharma, Papiya Mitra Mazumder
pp. s501–s509 · DOI: 10.5530/ijper.55.2s.121 · Published 2021
Background: The immune system plays an important role in various diseased conditions. Patients with compromised immune function are at increased risk of exposure. Thus, the evaluation of immunomodulatory activity of plan…
Article
Green-synthesis of Silver Nanoparticles by Hygrophila auriculata Extract: Innovative Technique and Comprehensive Evaluation
Smita Nayak, Priyanka Ghugare, Bhaskar Vaidhun
pp. s510–s517 · DOI: 10.5530/ijper.55.2s.122 · Published 2021
Background: Metal nanoparticles are of great scientific interest as they bridge the gap between the bulk and atomic structures. A number of methods of synthesizing nanoparticles have been developed and can be grouped int…
Article
The Anti-inflammatory Effect of Ethanol Extract Gel of Fig Leaves (Ficus carica Linn.) and Sidr Leaves (Ziziphus mauritiana Linn.)
Muhammad Fariez Kurniawan, Ariffadli Prakoso, Muhammad Indra Irawan
pp. s518–s527 · DOI: 10.5530/ijper.55.2s.123 · Published 2021
Inflammation is a form of the body's response to tissue damage with a sign of epidermal thickness, an increase in the number of inflammatory cells and the expression of the COX-2 enzyme. The fig leaves and sidr dry leave…
Article
Neuroprotective Effect of Petroleum Ether, Methanolic and Aqueous Extracts of Fruits of Benincasa hispida on Lipofuscinogenesis and Fluorescence Product in Brain of D-galactose Induced Aging Accelerated Mice
Digambar Balkrishna Ambikar, Guru Prasad Mohanta
pp. s528–s534 · DOI: 10.5530/ijper.55.2s.124 · Published 2021
Background: Aging is one of the major factors of development of neurodegenerative disorder and also involved in gradual learning and memory loss. In recent years discovery of antiaging drugs is one of the important topic…
Article
Scientific Evaluation of Anti-obesity Potential of Methanolic Leaves extract of Ocimum sanctum (Linn.) in Monosodium Glutamate - High Fat Diet Induced Obese Mice
Satyajit Mohanty, Ashok Pattnaik
pp. s535–s543 · DOI: 10.5530/ijper.55.2s.125 · Published 2021
Background: obesity is the deposition of body fat mass from the imbalance between calorie intake and vitality consumption. The metabolic syndrome brings the risk of health hazards like type-2diabetes, stroke and cardiova…
Article
Endophytic Fungi, Drechslera spicifera, Mediated Synthesis of Biogenic Silver Nanoparticles
Sharada Laxman Deore, Bhushan Arun Baviskar, Preeti N Sonar, Anjali Ashokarao Kide, Bhavana Ashokarao Shende
pp. s544–s551 · DOI: 10.5530/ijper.55.2s.126 · Published 2021
Aim: In present communication, endophytic fungi Drechslera spicifera is isolated from leaves of Cardiospermum halicacabum and used as a reducing agent for silver nanoparticles (AgNPs) synthesis. Materials and Methods: Sy…
Article
Methanolic Extract of Angelica glauca Edgew Root and Stem: A Possible Component of Herbal Medicines against Respiratory Infections
Prashant Arya, Jagat Prakash Mehta, Vineet Kumar Maurya
pp. s552–s562 · DOI: 10.5530/ijper.55.2s.127 · Published 2021
Plants are identified to produce a variety of compounds to protect themselves against a diversity of pathogens. This study assessed the antibacterial, antioxidant potential and phytochemical screening of medicinal plant …
Article
Protective Effect of Boerhavia diffusa in Attenuating Pro-inflammatory Cytokines and Inhibition of Activated NF-κB-TNF-α-Nrf2 in Freund’s Adjuvant-induced Rheumatoid Arthritis
Ritu Karwasra, Shivkant Sharma, Nitin Sharma, Kushagra Khanna
pp. s563–s571 · DOI: 10.5530/ijper.55.2s.128 · Published 2021
Background: Boerhavia diffusa is widely used in Asian and African countries in the treatment of inflammatory disorders in adjunct with other herbal formulations. The current research work was devised with an aim to exami…
Article
Development and Validation of Ultraviolet Spectroscopic Method for Estimation of Methoxsalen in Bulk Using Methanol and Phosphate Buffer (pH 7.4)
Shraddha Unde, Nalini Kurup
pp. s572–s579 · DOI: 10.5530/ijper.55.2s.129 · Published 2021
Background: Psoriasis is an inflammatory condition of a body wherein erythematous, sharply demarcated papules and round-shaped plaques appear onto skin due to the hyperproliferation of epidermis. Psoralens are the class …
Article
Synchronized Quantitative Assessment of Corticosteroid and Bronchodilator in Rotacaps by HPTLC using Fractional Factorial Design
Aarti Sachin Zanwar, Dhanya B Sen, Charu Paresh Pandya, Avinash Kumar Seth, Rajesh Maheshwari, Ashim Kumar Sen
pp. s580–s588 · DOI: 10.5530/ijper.55.2s.130 · Published 2021
Background: A validated high performance planar chromatographic analysis for a combination medication of corticosteroids mometasone furoate and bronchodilators formoterol fumarate available as Evocort®: inhaler in market…
Article
Novel Analytical Method Development, Validation and Stability Study of Anticancer Drug Erlotinib in Tablet Dosage Form by RP-UFLC
K Purvini, Chethan IA, Jaishree Vaijanathappa
pp. s589–s594 · DOI: 10.5530/ijper.55.2s.131 · Published 2021
Present work is aimed to develop a novel, simple and accurate reverse phase-ultrafast liquid chromatographic (RP-UFLC) method for erlotinib (ELB) in tablet dosage form. The chromatogram was achieved by using Eclipse plus…

Analysis

Article
Synthesis and Anticonvulsant Evaluation of 3-(5-(4-substitutedphenyl)-4,5-dihydro-1H-pyrazol-3-ylamino)-2-(2-methylphenyl)quinazolin-4(3H)-one Derivatives
Sachin Kumar, Keshari Kishore Jha, Rati Kailash Prasad Tripathi, Nishant Kumar, Anurag Chaudhary
pp. s595–s604 · DOI: 10.5530/ijper.55.2s.132 · Published 2021
: Epilepsy arise due to discharge of electric current in CNS and it is Characterized by repeated seizure because of different factors like social, neurological and environmental or it may be due to genetic or non-genetic…
Article
Assessment of Toxicity and Drug-Drug Interaction of Combination Therapy Prescribed by Physicians/ Clinicians for Treatment of Diabetes using Experimental Animals
Hemlata Dewangan, Raj Kumar Tiwari, Vikas Sharma, Shiv Shankar Shukla, Ravindra Kumar Pandey
pp. s605–s615 · DOI: 10.5530/ijper.55.2s.133 · Published 2021
Purpose: The management of diabetes associated with hyperlipidemia is a challenge not only to the physician but also to medical fraternity. Hence most of the physicians prefer to prescribe antihyperglycemic drug along wi…
Article
A Recent Regulatory Update on Consequences of Data Integrity Issues and its Management in Pharmaceutical Scenario
Remya James, Srija Das, Anjali Kumari, Mikal Rekdal, Girish Pai Kulyadi, Muddukrishna Badamane Sathyanarayana
pp. s616–s622 · DOI: 10.5530/ijper.55.2s.134 · Published 2021
Purpose: Pharmaceutical industry ensures that data entered for various steps of drug development is accurate, which gives us confidence that the drugs produced by the industry are within specified parameters. Data integr…