Indian Journal of Pharmaceutical Education and Research
Volume 55, Issue 1S
2021 · pp. 0–121 · 33 articles
- Volume
- 55
- Issue
- 1S
- Published
- 2021
- Pages
- 0–121
- Articles
- 33
- Sections
- 3
- ISSN
- Online - 0019-5464
- Journal
- IJPER
In this issue
Review Article
- Review
Nano-transethosomes: A Novel Tool for Drug Delivery through Skin
Kajal Jagdish Bajaj, Bhagyashri Surendra Parab, Supriya Shrihari Shidhaye
pp. S1–S10 · DOI: 10.5530/ijper.55.1s.33 · Published 2021
Transdermal drug delivery has become a popular tool from last few years. It overcomes drawbacks which are encountered with the oral route. Though very few routes are as attractive as transdermal route, transport of drug …
- Review
Niosome as a Novel Pharmaceutical Drug Delivery: A Brief Review Highlighting Formulation, Types, Composition and Application
Mahesh Gajanan Umbarkar
pp. S11–S28 · DOI: 10.5530/ijper.55.1s.34 · Published 2021
Aim: Formation of niosome by using non-ionic surfactant. The particle size of niosome must be required in the range in between 10 nm -100 nm. This is just due to avoid the aggregation of niosome and show proper result. M…
- Review
Natural Chimeras of Existing Drugs for Alzheimer’s Disease: Expanding the Target Landscape
Illham Dhala, Tabassum Khan, Arati Prabhu
pp. S29–S47 · DOI: 10.5530/ijper.55.1s.35 · Published 2021
Alzheimer’s disease (AD) has emerged as a complex, multi-faceted, neurodegenerative disorder. Multiple mechanisms seem to play a part in its pathogenesis, including amyloid beta aggregation, cholinergic deficit, oxidativ…
Original Article
- Article
Bioactive Compound Bisacurone in the Turmeric Extract (Turcuron) Prevents Non-alcoholic Fatty Liver Disease by Reduction of Lipogenesis
Kuluvar Gouthamchandra, Heggar Venkataramana Sudeep, Amritha Raj, Illuri Ramanaih, Chandrappa Siddappa, Kodimule Shyamprasad
pp. S48–S55 · DOI: 10.5530/ijper.55.1s.36 · Published 2021
Objectives: The current study was carried out to demonstrate potential role of Turcuron, a standardized turmeric extract containing 8% Bisacurone to protect against non-alcoholic fatty liver disease (NAFLD). Methods: Hep…
- Article
Solubility Enhancement of Oxcarbazepine by Melt Sonocrystallization Technique to Increase the Bioavailability
Vinayak Shivamurthy Mastiholimath, Gauri Pradeep Mashelkar, Vinodkumar Shirshalappa Mannur, Panchaxari Mallappa Dandagi, Pukar Khanal
pp. S56–S65 · DOI: 10.5530/ijper.55.1s.37 · Published 2021
Objectives: The present study aimed to enhance the solubility of Oxcarbazepine by melt sono crystallization technique as well as increase its bioavailability. Materials and Methods: Tablets of Melt Sonocrystallized Oxcar…
- Article
Transdermal Delivery of Fluconazole ß-cyclodextrin Complex Incorporated in Aloe vera Gel for Fungal Therapy: Development, Characterization and in vitro Evaluation
Deepak Aswal, Tanuja Bisht
pp. S66–S74 · DOI: 10.5530/ijper.55.1s.38 · Published 2021
Aim: The aim of the present investigation was to increase the dissolution rate of Fluconazole by solid dispersion technique and then it was incorporated into the gel for better diffusion profile. Fluconazole, an imidazol…
- Article
Preparation, Characterization and Optimization of Repurposed Valproic Acid Loaded Carboxymethyl Chitosan Nanoparticles by Box–Behnken Design for Alzheimer Management
Ayush Jaiswal, Senthil Venkatachalam, Anindita De, Bhavesh Namdev, Ravikumar Ramaswamy, Jawahar Natarajan
pp. S75–S86 · DOI: 10.5530/ijper.55.1s.39 · Published 2021
Aim/Background: Alzheimer’s disease (AD) is one of the most ominous diseases, leads dementia but highest unmet till today. The new strategy needed via repositioning due to the limitation of existing therapies. Valproic a…
- Article
Studies on Formulation and Evaluation of Eudragit RS PO Based Nanoparticulate System of Aceclofenac for Ocular Delivery
Sfurti Sakhare, Sachin Dnyandeo Shinde, Adhikrao Venkatrao Yadav, Amol Somnath Shete
pp. S87–S99 · DOI: 10.5530/ijper.55.1s.40 · Published 2021
Aim: Ocular drug delivery is the most challenging and interesting goal in front of the pharmaceutical scientist. Ocular inflammation is the most commonly affecting disease of the eye. The objectives of present investigat…
- Article
Gastroretentive Floating Tablets Enclosing Nanosponge Loaded with Lafutidine for Gastric Ulcer: Formulation and Evaluation
Poornima Poornima, Sneh Priya
pp. S100–S111 · DOI: 10.5530/ijper.55.1s.41 · Published 2021
Aim and Objectives: The present study aimed to formulate and evaluate gastroretentive nanosponge loaded with lafutidine for a gastric ulcer to overcome the drawbacks of oral conventional dosage forms such as the inabilit…
- Article
Formulation and Evaluation of Orodispersible Tablets of Apremilast by Inclusion Complexation using β-Cyclodextrin
Darshana Pravinchandra Panhale, Rishikesh Shankar Bachhav, Sheetal Bhaskar Gondkar
pp. S112–121 · DOI: 10.5530/ijper.55.1s.42 · Published 2021
Introduction: The present study was carried out to formulate and evaluate orodispersible tablets of Apremilast with a purpose of providing better patient compliance to geriatric, pediatric, impaired, travelling and non-c…
- Article
Acyclovir Loaded Solid Lipid Nanoparticulate Gel for Ocular Delivery: Optimization by using Factorial Design
Subhabrota Majumdar, Suryakanta Swain, Muddana Eswara Bhanoji Rao, Puja Chakraborty, Sabya Sachi Das
pp. S122–S134 · DOI: 10.5530/ijper.55.1s.43 · Published 2021
Background: Acyclovir is a potent antiviral agent primarily used to treat viral infection in the eye, signified as Herpes Simplex Keratitis caused by Herpes Simplex Virus-1. But its applications are limited because of it…
- Article
Development of Raloxifene Hydrochloride Loaded mPEG-PLA Nanoparticles for Oral Delivery
Shabari Girinath Kala, Santhivardhan Chinni
pp. S135–S148 · DOI: 10.5530/ijper.55.1s.44 · Published 2021
Objectives: Raloxifene hydrochloride is used in the treatment of breast cancer which suffers from poor bioavailability problem i.e., only 2% due to excessive first pass metabolism. Development of a delivery system to ove…
- Article
Investigation of Solubility of Mebendazole Drug using Linear Prediction and Multilayer Feed Forward Neural Network
Chathurappan Raja, V Sampath Kumar, Chinnakannu Jayakumar
pp. S149–S156 · DOI: 10.5530/ijper.55.1s.45 · Published 2021
Objectives: A systematic in-vitro study has been achieved to decide the stability of a selection of three presidential hydrotropes to decorate the obvious aqueous solubility of the sparingly water- soluble drug, mebendaz…
- Article
Evaluation of Controlled Release Patterns of Ornidazole using Bio-degradable Polymers and Determination of its Antibacterial Activity
Mahesh Neurgaonkar, Shaila Veerappa Kothiwale
pp. S157–S163 · DOI: 10.5530/ijper.55.1s.46 · Published 2021
Aim: Controlled release (CR) local drug delivery (LDD) devices are useful in periodontitis management since they facilitate prolonged maintenance of high antimicrobial concentrations in the periodontal pockets. The study…
- Article
Development of Budesonide Oral Colon Specific Drug Delivery System using Interpolymer Complexation Method
Patil Ramgonda, Rajashree Shashidhar Masareddy, Archana Patil, Uday Bolmal
pp. S164–S174 · DOI: 10.5530/ijper.55.1s.47 · Published 2021
Background: Oral bioavailability of Budesonide is 10% due to its extensive first pass metabolism, its high volume of distribution and 85-90% of protein binding. Protection of drug release in stomach and targeting drug to…
- Article
Evaluation of Some Phenolic Acids in Diabetic Neuropathy
Shubhangi Pawar, Aman Upaganlawar, Chandrashekhar Upasani
pp. S176–S183 · DOI: 10.5530/ijper.55.1s.48 · Published 2021
Background: Streptozotocin (STZ) induced neuropathy is widely used preclinical model for diabetic neuropathy (DN). DN is majorly resulted due to nitrosative and oxidative stress induced by hyperglycemia. Phenolic acids a…
- Article
Protective Effect of Plumeria obtusa Leaves Extracts on Dexamethasone-induced Insulin-resistance Diabetes Mellitus in Rats
Sumeet Gupta, Hitendra Sharma, Mohamed Aly Morsy, Anroop Balachandran Nair, Kamalpreet Kaur, Satish Kumar, Meenakshi Dhanawat
pp. S184–S192 · DOI: 10.5530/ijper.55.1s.49 · Published 2021
Background: Plumeria obtusa L., a potential medicinal plant, is still unexplored for its anti-diabetic effect. The objective of this study was to examine the protective effect of Plumeria obtusa leaves extracts on insuli…
- Article
Response Surface Optimization of Flavonoids Extraction, Beta Carotene Bleaching and Lipid-reducing Capacity of Nelumbo nucifera Seed Kernel Extracts
Haq Nawaz, Muhammad Aslam Shad, Mohibullah Shah, Adnan Amjad, Tanzila Rehman, Arif Mehmood, Dure Shahwar, Sabiha Tahir Abbasi
pp. S193–S201 · DOI: 10.5530/ijper.55.1s.50 · Published 2021
Aim/Background: The safe and complete extraction of flavonoids from plant material influenced by various factors has been ever challenging for the researchers. The study was planned to optimize the extraction of flavonoi…
- Article
Biogenic Synthesis of Silver Nanoparticles (AgNPs) using Solanum indicum Linn.
Sadeq Khalid Alhag, Hamed Ali Ghramah, Lamya Ahmed Al-keridis, Fahd Abdu Al-Mekhlafi, Essam Hassan Ibrahim, Khalid Ali Khan
pp. S202–S208 · DOI: 10.5530/ijper.55.1s.51 · Published 2021
Background: Synthesis of silver nanoparticles (AgNPs) using green plants is important for biocompatibility, reduced hazards, green policy and eco-friendliness. Materials and Methods: In this study, a leaf extract of Sola…
- Article
Exploration of Elephant Foot Yam (Amorphophallus paeoniifolius) Starch: An Alternative Natural Disintegrant for Pharmaceutical Application
Ujjwala Yadav Kandekar, Tejal Ramdas Abhang, Rohini R. Pujari, K.R. Khandelwal
pp. S209–S219 · DOI: 10.5530/ijper.55.1s.52 · Published 2021
Aim and Objectives: The aim of the current study is to isolate the starch from elephant foot yam (Amorphophallus paeonifolius) and investigate its potential as a disintegrant in tablet formulation as compare to standard …
- Article
Silver Nanoparticles Biosynthesized from Vaccinium myrtillus L. against Multiple Antibiotic Resistance and Biofilm Forming Escherichia coli and Pseudomonas aeruginosa
Nilay Ildiz, Firdevs Korkmaz, Sadi Yusufbeyoğlu, Ayşe Baldemir Kilic, İsmail Ocsoy
pp. S220–S224 · DOI: 10.5530/ijper.55.1s.53 · Published 2021
Background: Despite new innovations and process improvements, biofilm forming bacterial infections still pose a serious threat to patients. Silver nanoparticles (AgNPs) have been shown to have antibacterial properties an…
- Article
In-vitro and in-vivo Immunomodulatory Effect of Polyherbal Suspension on Cyclophosphamide Induced Experimental Animal
Ashish Majumdar, Shiv Shankar Shukla, Ravindra Kumar Pandey
pp. S225–S232 · DOI: 10.5530/ijper.55.1s.54 · Published 2021
Aim: The aim of present investigation was to determine the efficacy of a polyherbal formulation. [Composed of Nelumbo nucifera (NN), Euryale ferox (EF) and Trapa natans (TN)]. Materials and Methods: The seeds of NN and E…
- Article
Synthesis, Identification and in-silico Approach for wound Healing Potential in Gnaphalium polycaulon Extracts
Karuppusamy Shanmugapriya, Periaswamy Sivagnanam Saravana, Rajakumari Karuppusamy, Thangavelu Thayumanavan
pp. S233–S241 · DOI: 10.5530/ijper.55.1s.55 · Published 2021
Aim/Background: The secondary metabolites can be identified from G. polycaulon and used as effective compounds for wound healing potential. The aims of the present study to identify the metabolites from G. polycaulon ext…
- Article
Biopreservative Action of Bacteriocin from Pediococcus pentosaceus on the Microbial Load of Apple Juice
Riyanka Majumder, Ankita Aditya, Sreyosi Dey, Jannatul Firdous Siddique, Nivetha Anbalagan, Subathra Devi, Mohanasrinivasan Vaithilingam
pp. S242–S250 · DOI: 10.5530/ijper.55.1s.56 · Published 2021
Aim: The aim of the study is to explore the bio preservative role of Pediococcus pentosaceus. Background: Bacteriocins are proteinaceous or peptidic in nature produced by lactic acid bacteria and generally recognized as …
- Article
Therapeutic Interventions using Monotherapy versus Combination Therapy of Aloe vera and Omega-3 Fatty Acids on Gentamicin-initiated Renal Toxicity via Attenuation of Renal Biomarkers
Rajesh A. Maheshwari, Gurpreet Kaur, Dhanya B. Sen, Ghanshyam Parmar, Ramachandran Balaraman, Avinash K. Seth, Ashim K. Sen
pp. S251–S258 · DOI: 10.5530/ijper.55.1s.57 · Published 2021
Background and Aim: The proposed work was planned to evaluate the potential protective role of aqueous Aloe vera (AV) concentrate and/or Omega-3 fatty acids (O3FAs) against GM -initiated renal toxicity in rats. Materials…
- Article
Translational Allergy and Omalizumab: The Pioneer
Maria Maddalena Sirufo, Francesca De Pietro, Enrica Maria Bassino, Lia Ginaldi, Massimo De Martinis
pp. S259–S264 · DOI: 10.5530/ijper.55.1s.58 · Published 2021
Backgound: The introduction of monoclonal antibodies into therapy has brought great progress in every field of medicine. Omalizumab is the first monoclonal antibody successfully used in allergology. We wanted to evaluate…
- Article
Ethanolic Extract of Capparis decidua Fruit Ameliorates Methotrexate-Induced Hepatotoxicity by Activating Nrf2/HO-1 and PPARγ Mediated Pathways
Preetha Santhakumar, Anitha Roy, Karthik Ganesh Mohanraj, Selvaraj Jayaraman, Rajkumar Durairaj
pp. S265–S274 · DOI: 10.5530/ijper.55.1s.59 · Published 2021
Introduction: Methotrexate, a folate antimetabolite, immunosuppressant and cytotoxic chemotherapeutic agents employed for malignant conditions. Continuous exposure of methotrexate produces adverse side effects especially…
- Article
Docking Studies and Evaluation of Antimicrobial Activity of Chroman Carboxamide Derivatives
Pinki Rawat, Saurabh Manaswita Verma, Piyush Kumar
pp. S275–S284 · DOI: 10.5530/ijper.55.1s.60 · Published 2021
Aim: Based on our previous work, a series of chroman derivatives, which were first used as antiepileptic agents, are evaluated for their antimicrobial potency. Materials and Methods: The present study involves docking st…
- Article
Smart UV Derivative Spectrophotometric Methods for Simultaneous Determination of Metformin and Remogliflozin: Development, Validation and Application to the Formulation
Smart UV Derivative Spectrophotometric Methods for Simultaneous Determination of Metformin, Remogliflozin: Development, Validation Validation, Application to the Formulation
pp. S293–S302 · DOI: 10.5530/ijper.55.1s.62 · Published 2021
Background: The result of pharmaceutical industry research for the new class and the new combination of drugs for the treatments of diabetes is the newly approved combination of metformin (MET) and remogliflozin (REM). F…
- Article
Quantification of Fluoxetine in Human Plasma by the Development of Liquid Chromatography-tandem Mass Spectrometry Method
Geeta Negi, Jaseela Majeed, Saurabh Arora, Sachin Rana, Manoj Singh, Jaideep Tomar
pp. S303–S311 · DOI: 10.5530/ijper.55.1s.63 · Published 2021
Aim: The aim of this research paper is the development and validation of an easy, selective and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of fluoxetine in human K3E…
- Article
Investigation of the Effects of Polypharmacy on Cognitive Functions: Cohort Study
Muhammed Yunus Bektay, Mustafa Gokce, Rabia Selvitop, Erkut Bolat, Gulsen Babacan Yildiz
pp. S312–S317 · DOI: 10.5530/ijper.55.1s.64 · Published 2021
Background: Alzheimer’s Disease (AD) is a major concern in growing chronic diseases in the geriatric society and its connection with polypharmacy has not been sufficiently understood. Aim: This Study investigate the asso…
- Article
Clinical Pharmacist Approach towards Effectiveness of Pulmonary Rehabilitation of the Patient with COPD: A Randomized Controlled Study
Mahantha Vastrad, Shashikala Wali, Madiwalayya Shivakantayya Ganachari, Ashish Singh Parihar, Ramesh Bhandari
pp. S318–S324 · DOI: 10.5530/ijper.55.1s.65 · Published 2021
Background: COPD is characterized by chronic obstruction of lung airflow that interferes with normal breathing and is not fully reversible. Pulmonary rehabilitation is widely accepted as a best result outcome treatment f…
Commentary
- Article
Applicability of Group Discussion as a Pedagogic Practice in a Classroom Setting in Health Education- A Brief Commentary
Astha Chaudhry
pp. s325–s325 · DOI: 10.5530/ijper.55.1s.66 · Published 2026
Student centered learning (SCL) has brought a paradigm shift in the concept of teaching and learning process from an “Instruction paradigm” to “Learning paradigm”. Based on the Andragogic principles of ‘self- directed le…