Volume 14, Issue 1

Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy, Lizanne Fernandes, Sadaf Sultana, Saurav Raj, Megha Hegde, Dhananjay Tikadar, Aju Alex, Raviteja Kanavi

pp. 165–171 · DOI: 10.5530/ijpi.14.1.21 · 2023

Background: Postpartum Depression (PPD) is one of the least vocalized topics surrounding pregnancy and motherhood in India. The study aimed to assess the postpartum depression in women who had cesarean and normal vaginal…

Rohit Jaysing Bhor, Adesh Chandrakant Agale, Gaikwad Mayur Sitaram, More Dhanraj Navnath, Wayse Siddheshwar Sunil

pp. 172–179 · DOI: 10.5530/ijpi.14.1.22 · 2023

Background:The serine/threonine kinase p38 Mitogen-Activated Protein (MAP) kinase is one of the most well studied kinases in the inflammatory process. The goal of this study was to see how a p38 MAP Kinase inhibitor (PDB…

Jisha Mohanan, Gopinath Subramaniyan, Arul Kuttalingam, Damodharan Narayanasamy

pp. 180–185 · DOI: 10.5530/ijpi.14.1.23 · 2023

Introduction: The study aimed to assess the bioavailability of two sublingual formulations i.e., fast-dissolving films and tablets of the poorly bioavailable immunosuppressant drug, tacrolimus, and to compare with its ma…

Aayushi Jaiswal, Mudumba Srivarshini, Patlolla Akshitha Reddy, Tripura Sundari, Sirisha Sunkavalli, Ramya Vandanasetti, Shaheen Begum, Arifa Begum SK

pp. 186–190 · DOI: 10.5530/ijpi.14.1.24 · 2023

Background:The Levonorgestrel-releasing intrauterine system was inserted in patients with conditions like Abnormal Uterine Bleeding (AUB), adenomyosis and Perimenopausal Bleeding (PMB). This study aimed to find the effec…

Sandhya Murali, Prasanth Viswanadhan Vasantha

pp. 191–203 · DOI: 10.5530/ijpi.14.1.25 · 2023

Purpose:This study aimed to prepare and evaluate mucoadhesive buccal patches of Sumatriptan Succinate (SUS) made from natural polymers to improve bioavailability, patient compliance, and dose-dependent adverse effects as…

Kalepu Eswar Krishna Sai, Medidi Srinivas, Bula Udaya Kumari, Chepyala Sumalatha, Arram Madhavi

pp. 204–211 · DOI: 10.5530/ijpi.14.1.26

Objectives: A straightforward, accurate, and precise reverse-phase high-performance liquid chromatography method was developed to determine the quantity of Lobeglitazone in both bulk and pharmaceutical dosage forms. Mate…

Tejas B Patel, Shantilal P Padhiyar, Vipul T Prajapati, Vashisith P Bhavsar, Nishit D. Patel, Dharmik A. Shah

pp. 212–224 · DOI: 10.5530/ijpi.14.1.27 · 2023

Background:This research was conducted to create a treatment for osteoporosis (bone degenerating disorder) with hormone replacement therapy using Hydroxyapatites and chitosan as a composite. The research aims to develop …

Pravalika Mupparapu, Afra Azeenath, Tahsina Firdous, Tamanna Yeasmin, Mohd Azharuddin

pp. 225–231 · DOI: 10.5530/ijpi.14.1.28 · 2023

Background: Diabetes is persistent illness that develops mostly when the body produces insufficient amount of the insulin hormone. The insulin hormone regulates blood glucose levels. In recent epidemiological research st…

Sanju Trizah Saji, Prasanth Viswanadhan Vasantha

pp. 232–238 · DOI: 10.5530/ijpi.14.1.29 · 2023

Aim and Objectives: This study examined SSRI-related adverse drug reactions (ADRs), medication adherence, commonly prescribed SSRIs, and gender and age distribution in patients with depression at three tertiary care hosp…

Ayesha Naz, CVS Subrahmanyam, Shyam Sunder Rachamalla

pp. 239–249 · DOI: 10.5530/ijpi.14.1.30 · 2023

Background:The present study aims to develop an Elementary Osmotic tablet (EOP) of Rivastigmine Hydrogen Tartrate (RHT). EOP consists of a core tablet suitably coated with a polymeric solution, and an orifice drilled on …

Anand Shripal Ammanage, Vinayak Shivamurthi Mastiholimath

pp. 250–257 · DOI: 10.5530/ijpi.14.1.31

Background:Diabetes is an endocrine disorder characterized by an abnormal increase in blood sugar level. Vildagliptin is a Dipeptidyl Peptidase-4 (DPP-4) inhibitor used in the treatment of type 2 diabetes mellitus. Purpo…

Lekhana Bandi, Naga Shivani Lakshmisetty, Keerthana Ankireddy, Leela Lakshmi Vaishnavi Pulipati, Asritha Lakshmi Bontu, Ranganadha Reddy Aluru, Chandrasekhar Chanda

pp. 258–262 · DOI: 10.5530/ijpi.14.1.32 · 2023

Objectives:Lipases are widely used in biodiesel, food, detergent, and pharmaceutical industries. To fulfil the rising demand for these crucial industrial enzymes, an extensive study on lipases from various micro-organism…

Megha Hegde, Saurav Raj, Anil Ashvil, Dhananjay Tikadar, Sanatkumar Bharamu Nyamagoud

pp. 263–267 · DOI: 10.5530/ijpi.14.1.33 · 2023

Background: Toxic Epidermal Necrolysis (TEN), also known as Lyell's syndrome, is a rare but severe connective tissue condition that is a common cause of substantial skin damage as well as mucous membrane breakdown. This …