Zero Order Spectrophotometric Method for Estimation of Escitalopram Oxalate in Tablet Formulations
Sharma S1★, Rajpurohit H1, Sonwal C2, Bhandari A1, Choudhary VR1, Jain T1★ Corresponding author
- 1Faculty of Pharmaceutical Sciences, Jodhpur National University, Jodhpur, INDIA.
- 2Rajasthan Drug and Pharmaceutical Ltd, V.K.I. A. Road no. 12, Jaipur, INDIA.
CORRESPONDENCE
Sharma S
Faculty of Pharmaceutical Sciences, Jodhpur National University, Jodhpur, INDIA.
Volume 2, Issue 4 · pp. 420–423 · PUBLISHED · DOI: 10.4103/0975-1483.71626
ABSTRACT
A new, simple, fast and reliable zero order spectrophotometric method has been developed for determination of Escitalopram Oxalate in bulk and tablet dosage forms. The quantitative determination of drug was carried out using the zero order values (absorbance) measured at 238 nm. Calibration graph constructed at 238 nm was linear in concentration range of 2-20 μg/ml with correlation coefficient 0.9999. The method was found to be precise, accurate, specific, and validated as per ICH guidelines and can be used for determination of Escitalopram Oxalate in tablet formulations.
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S, S., H, R., C, S., A, B., VR, C., & T, J. (). Zero Order Spectrophotometric Method for Estimation of Escitalopram Oxalate in Tablet Formulations. Journal of Young Pharmacists, 2(4), 420–423. https://doi.org/10.4103/0975-1483.71626