Journal of Young Pharmacists
Volume 8, Issue 4
· pp. 293–506 · 32 articles
- Volume
- 8
- Issue
- 4
- Published
- Pages
- 293–506
- Articles
- 32
- Sections
- 5
- ISSN
- Print - 0975-1483 | Online - 0975-1505
- Journal
- JYP
In this issue
Editorial
- Forum Article
Need for the Refinement of Licensing Procedure for Pharmacists in India
Ramalingam Peraman, Hari Hara Theja Dugga
pp. 293 · DOI: 10.5530/jyp.2016.4.1 · Published
As per the Pharmacy practice regulation of Pharmacy council of India, 2015 there are numerous numbers of pharmacist roles have been described in the official gazette of Govt. of India. The participation of a registered p…
Meta Analysis
- Article
Scientometric Assessment of India’s Migraine Research Publications during 2006-15
Ritu Gupta, B. M. Gupta, Jivesh Bansal, Ashok Kumar
pp. 294–301 · DOI: 10.5530/jyp.2016.4.2 · Published
The present study examines 579 Indian publications on “Migraine” research as covered in Scopus database during 2006-15, experiencing an annual growth rate of 17.37%, citation impact per paper of 8.32, international colla…
- Article
A Scientometric Assessment of Indian Publications on Vitamin D Deficiency during 2006-15
Ritu Gupta, B. M. Gupta, Kiran Baidwani, Jeevanjyot Kaur
pp. 302–309 · DOI: 10.5530/jyp.2016.4.3 · Published
The present study examines 536 Indian publications on “Vitamin D Deficiency” as covered in Scopus database during 2006-15, experiencing an annual average growth rate of 37.08%, citation impact per paper of 8.30 and inter…
- Article
Clinical Pharmacology Research in India: A Scientometric Assessment of Publication Output during 2005-14
K K Mueen Ahmed, B. M. Gupta, Ritu Gupta
pp. 310–318 · DOI: 10.5530/jyp.2016.4.4 · Published
The paper examines 8519 publications on clinical pharmacology research in India as covered in Scopus database during 2005-14, using various quantitative and qualitative parameters with a focus on its growth, citation qua…
Original Artcile
- Article
Synthesis and Biological Evaluation of some 3b-hydroxy-lup-20(29)-en-28-oic Acid Derivatives
Prince Prashant Sharma, Anurag A, Ram Kumar Roy, Rajneesh Dutt Kaushik, Vipin Kumar Sharma
pp. 319–323 · DOI: 10.5530/jyp.2016.4.5 · Published
Objective:The present study projected to the synthesis of 3b-Hydroxy-lup- 20(29)-en-28-oic acid analogues in order to evaluate their possible biological activity. In addition, the structure–activity relationship is also …
- Article
Formulation Development and Evaluation of a Gastroretentive in situ oral gel of Cefuroxime Axetil
Divyesh Harshadkumar Shastri, Hitesh Dhirubhai Dodiya, Pragna Shelat, Alkesh Kishanlal Bhanupriy
pp. 324–329 · DOI: 10.5530/jyp.2016.4.6 · Published
Objective: To develop a gastroretentive in situ oral gel to improve the bioavailability of the cephalosporin antibiotic drug, Cefuroxime Axetil. Methodology:Sodium alginate and pectin were the ionic dependent gel forming…
- Article
Formulation and Evaluation of Chitosan Nanospheres Containing Methotrexate Targeted Drug Delivery System
Sokkalingam Arumugam Dhanaraj, Selvadurai Muralidharan, Vijayan Venugopal, Puspavathy Kanniappan, Winnie Tan Sze Hui, Lim Li Qi
pp. 330–334 · DOI: 10.5530/jyp.2016.4.7 · Published
Objective: The aim of the present study is to prepare and evaluate nanoparticles containing methotrexate using chitosan as the polymer. The MTX-loaded CS-NPs were prepared by the emulsion polymerization method using glut…
- Article
Enhancing Transdermal Delivery of Glimepiride Via Entrapment in Proniosomal Gel
Marwa Helmy Abdallah, Shereen Ahmed Sabry, Azza Ali Hasan
pp. 335–340 · DOI: 10.5530/jyp.2016.4.8 · Published
Objective: The aim of this study is to formulate and evaluate proniosomal gel formulations as transdermal delivery systems of glimepiride (GM) to improve its therapeutic efficacy. Methods:Proniosomal formulations have be…
- Article
Development of Fast Dissolving Tablets of Nisoldipine by Solid Dispersion Technology using Poloxamer 407 and Poloxamer 188
Manimaran Vasanthan, Damodharan Narayanasamy
pp. 341–349 · DOI: 10.5530/jyp.2016.4.9 · Published
Objective:The aim of the present study is to design oral fast-release tablets of nisoldipine and to optimize the drug dissolution profile by modifying the carrier concentration. Poloxamer 407 and Poloxamer 188 were selec…
- Article
Use of Box-Behnken Experimental design for Optimization of process Variables in Iontophoretic delivery of Repaglinide
Sriram Pavani, Yamsani Madusudhan Rao, Yamsani Shravan Kumar
pp. 350–355 · DOI: 10.5530/jyp.2016.4.10 · Published
Objective:In this study, a Box-Behnken design (BBD) of response surface method was used to investigate and optimize the process parameters of Repaglinide. Repaglinide is a suitable candidate for iontophoretic delivery du…
- Article
Solubility Enhancement of Nebivolol by Micro Emulsion Technique
Santosh Kale Nemichand, Sharada Deore Laxman
pp. 356–367 · DOI: 10.5530/jyp.2016.4.11 · Published
Nebivolol is a third-generation beta-a drenoceptor antagonist. It differs from other beta-a drenoceptor an tagonists as it combines highly selective beta (1)-adrenoceptor antagonist properties with nitric oxide-mediated …
- Article
Development and Characterization of Thermosensitive intranasal Gel Containing Paliperidone Loaded Microspheres
Apurva Jatinbhai Maniyar, Grishma Mahendrabhai Patel, Pragna Krishnachandra Shelat, Anita Nanikram Lalwani
pp. 368–377 · DOI: 10.5530/jyp.2016.4.12 · Published
Purpose:The objective of the present investigation was to fabricate a thermosensitive gel containing paliperidone loaded microspheres for the treatment of schizophrenia for brain delivery through nasal route. Incorporati…
- Article
Evaluation of In vitro Antioxidant Properties of Hydro Alcoholic Extract of Entire Plant of Cynodon dactylon
Roopesh Poojary, Nayanatara Arun Kumar, Reshma Kumarachandra, Ganesh Sanjeev
pp. 378–384 · DOI: 10.5530/jyp.2016.4.13 · Published
Background:Antioxidant plays a key role in preventing and scavenging free radicals providing safeguard to humans against diseases. Recent research has been directed towards “Natural antioxidants” from the herbal plants d…
- Article
Preliminary Pharmacognostical and Phytochemical Screening of DiaKure–A Polyherbal Antidiabetic Formulation
Ujwala TK, Sandra Celine, Shawn Tomy, Arulraj P, Sam Johnson Udaya Chander J
pp. 385–390 · DOI: 10.5530/jyp.2016.4.14 · Published
Background: Diakure is an indigenously prepared hypoglycemic polyherbal formulation, containing mixture of Vetiveria zizanoides(root), Hemidesmus indicus (rhizome), Strychnos potatorum (seed), Salacia reticulata (bark), …
- Article
Phytochemical screening, Antioxidant, Thrombolytic, α-amylase inhibition and cytotoxic activities of ethanol extract of Steudnera colocasiifolia K. Koch leaves
Mohammad Shah Hafez Kabir, Mohammed Munawar Hossain, Md. Imtiazul Kabir, Md. Mominur Rahman, Abul Hasanat, Talha Bin Emran, Md. Atiar Rahman
pp. 391–397 · DOI: 10.5530/jyp.2016.4.15 · Published
Objective: Present study aims to investigate both qualitative and quantitative phytochemicals presence, antioxidant, thrombolytic, α-amylase and cytotoxic activity of a Bangladeshi plant Steudnera colocasiifolia K. Koch …
- Article
Alcoholic Extract of Wrightia tinctoria leaves and Isolates there of afford DNA Protection in Post Irradiated Sprague Dawley Rats
Sathianarayanan S, Asha Jose, Ranganathan Balasubramanian, Diana Thomas, Ashitha Balakrishnan, Rajasekaran Aiyalu
pp. 398–405 · DOI: 10.5530/jyp.2016.4.16 · Published
Objective: The current study investigates the potential of alcoholic extract of Wrightia tinctorialeaves and its isolates in repairing the DNA damage induced by gamma radiation. Methodology: The ethanolic extract ofWrigh…
- Article
Quantification of Blonanserin in Human Plasma Using Liquid Chromatography- Electrospray Ionization-Tandem Mass Spectrophotometry-Application to Pharmacokinetic Study
Mondal Prasenjit, Shobharani Satla, Ramakrishna Raparla
pp. 406–414 · DOI: 10.5530/jyp.2016.4.17 · Published
Background:A novel LC-MS/MS method was developed for the estimation of blonanserin (BLN) in spiked human plasma. Methods: Liquid-liquid extraction (LLE) technique was adopted for the extraction of BLN from human plasma a…
- Article
Quantification of Tamoxifen Polymeric Nanoparticles in female rodent breast tissue by UPLC/ESI-Q-TOF MS/MS
Md Aftab Alam, Niyaz Ahmad, Rizwan Ahmad, Sushama Talegaonkar, Farhan Jalees Ahmad, Zeenat Iqbal, Amulya K. Panda
pp. 415–423 · DOI: 10.5530/jyp.2016.4.18 · Published
Objective:The present work aims to develop and validate stability indicating a novel liquid chromatography method with applicability i.e. to study the pharmacokinetics factor as well as estimate Tamoxifen (TMX) in bio-an…
- Article
Simultaneous Estimation of Atorvastatin and Aspirin in Bulk and Capsule Dosage Form by Chemometric Assisted Spectrophotometric Methods
Keerthisikha Palur, Bharathi Koganti, Sreenivasa Charan Archakam, Sridhar Chenchugari, Bhavana Nagireddy, Mahesh Babu Devabhaktuni, Meenakshi Sankranthi
pp. 424–429 · DOI: 10.5530/jyp.2016.4.19 · Published
Objective: To develop the UV-spectrophotometric method and to apply the Chemometric designs to the developed method for the simultaneous estimation of Atorvastatin calcium (ATR) and Aspirin (ASP) in intact capsule dosage…
- Article
Stability Indicating HPTLC Determination of Triamcinalone Acetonide in Bulk Drug and Sterile Injectable Suspension
Girish Pai Kulyadi, Muddukrishna Badamane Sathyanarayana
pp. 430–435 · DOI: 10.5530/jyp.2016.4.20 · Published
A sensitive, accurate, precise and stability indicating high-performance thin layer chromatographic method was developed and validated for analysis of triamcinalone acetonide (TRIA) in bulk drug and sterile injectable su…
- Article
Effect of Voltage-Gated Calcium Channels (Cav) Blocker on Ovariectomy Induced Osteoporosis in Rats
Vijay Rajeshwarrao Chidrawar, Abdulkhaliq Jassem Alsalman, Sibghatullah Muhammad Ali Sangi
pp. 436–446 · DOI: 10.5530/jyp.2016.4.21 · Published
Objective: The present study was conducted to investigate the effect of two different doses of two calcium channel blockers i.e. verapamil and nifedipine on genesis and control of osteoporosis by considering various bioc…
- Article
Insight of Medical Students of Clinical Years to Antimicrobials Prescribing and Resistance in Private Medical School, Chittagong, Bangladesh
Rozina Hoque, Asma Mostafa, Mainul Haque
pp. 447–455 · DOI: 10.5530/jyp.2016.4.22 · Published
Background:Physicians formally receive education regarding antimicrobials and microbial resistance during a 5-6 year curriculum of the undergraduate medical program. However, the once magical bullet of antibiotics is now…
- Article
The Impact of Modern Pharmacy Curriculum on the Student Attitude towards Weight Loss Product Advertisements: A Case Study
Moawia M. Al-Tabakha, Dana Emad Eddin Obaid, Khairi M. S. Fahelelbom, Bassem Sadek
pp. 456–462 · DOI: 10.5530/jyp.2016.4.23 · Published
Objective:To investigate whether particular courses in modern pharmacy curriculum equips enrolled students with knowledge/skills to differentiate between different claims of weight loss products. Methods:Claims from weig…
- Article
Multi-Hierarchical Pattern Recognition of Athlete’s Relative Performance as A Criterion for Predicting Potential Athletes
Mohamad Razali Abdullah, Ahmad Bisyri Husin Musawi Maliki, Rabiu Muazu Musa, Norlaila Azura Kosni, Hafizan Juahir, Mainul Haque
pp. 463–470 · DOI: 10.5530/jyp.2016.4.24 · Published
Objective: This study investigates the relative performance quality pattern of athletes that trains under Terengganu sports development program based on physical fitness and psychological components. Methods: Relative pe…
- Article
A Survey on Knowledge, Attitude and Practice of Pharmacovigilance towards Adverse drug reactions reporting among Doctors and Nurses in a Tertiary Care Hospital in South India
Subramaniyan Ganesan, Gunaseelan Vikneswaran, Kishtapati Chenchu Reddy, DK Subrahmanyam, Chandrasekaran Adithan
pp. 471–476 · DOI: sganesh770@gmail.com · Published
Background:Spontaneous reporting of adverse drug reaction is globally practiced it under pharmacovigilance programme. But the major drawback of this system is underreporting. In this context the present survey was conduc…
- Article
An Exploratory Study on the Consumers Use of Medicine in the State of Sarawak, Malaysia
Chuo Yew Ting, Kah Seng Lee, Robin Tiow-Heng Tan, Wei Chern Ang, Long Chiau Ming
pp. 477–482 · DOI: 10.5530/jyp.2016.4.26 · Published
Introduction:The quality of a healthcare service relies on the rational use and the tight regulation of evidence-based medicine. By understanding how consumers take their medicines, policy makers were able to make approp…
- Article
The Effectiveness of Aerobic Exercises at difference Intensities of Managing Blood Pressure in Essential Hypertensive Information Technology Officers
Mohamad Razali Abdullah, Vijayamurugan Eswaramoorthi, Rabiu Muazu Musa, Ahmad Bisyri Husin Musawi Maliki, Norlaila Azura Kosni, Mainul Haque
pp. 483–486 · DOI: 10.5530/jyp.2016.4.27 · Published
Background:The appropriate exercise intensity has been shown to be effective in managing essential hypertension. However, this can be achieved only when an individual is aware of the right volume of the exercise intensit…
- Article
Hazardous Drug Handling Awareness Among Faculty Members
Noor Kamil
pp. 487–491 · DOI: 10.5530/jyp.2016.4.28 · Published
Background:Hazard to the health care professionals from hazardous drugs and chemicals rooted out from intrinsic toxicity and the level of exposure to these drugs in the course of their job responsibilities. Any drug or c…
Short Communication
- Communication
Structural and Optical studies of Traditional Indian Medicine: Kajjali & Narikela Lavan
Balkrishan Acharya, Mishra Nayan, Hira Narinder Kaur, Yadav Shailendra, Manikyam Hemanth Kumar, Chaudhary Ritu
pp. 492–495 · DOI: 10.5530/jyp.2016.4.29 · Published
Background:Traditional Indian system of medicine (Ayurveda) has its existence since ages but it is lacking characterization of drugs with the help of advanced techniques. It can help this system to find its place in toda…
- Communication
Antidiabetic effect of Polyherbal Formulation “Kathakakhadiradi Kashyam” in Streptozotocin induced Diabetic rats
Abdul Azeez, Shawn Tomy, Faisal Mohamed Ali Abdalla, R Suresh, Benito Johnson
pp. 496–499 · DOI: 10.5530/jyp.2016.4.30 · Published
Aim:The aim of the present study was to evaluate the antidiabetic potential of “kathakakhadiradi kashyam” (KKS) an indigenious polyherbal ayurvedic formulation in streptozotocin induced diabetes rat model. Methodology: I…
- Communication
Adoption and Reasons for Withdrawal of ICH Q1F Guidelines
Siddharth Jadeja, Girish pai kulyadi, Muddukrishna Badamane Sathyanarayana
pp. 500–504 · DOI: 10.5530/jyp.2016.4.31 · Published
ICH Q1 F guideline provided astability data package for the registration applications of drug substance and drug product in Climatic Zones III (hot and dry) and IV (hot and humid). These guidelines were adopted by the IC…
Letter to Editor
- Article
Acute renal damage in Acetaminophen poisoning
Faizan Mazhar, Shahzad Akram
pp. 505–506 · DOI: 10.5530/jyp.2016.4.32 · Published
Acetaminophen is one of the most commonly used analgesic globally. It is first-line pharmacologic agent for the symptomatic treatment of mild to moderate pain recommended by WHO. Acetaminophen may act as a potent hepatot…