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Journal of Young Pharmacists volume 9, issue 1 cover
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Cover: Journal of Young Pharmacists

Journal of Young Pharmacists

Volume 9, Issue 1

· pp. 1–139 · 28 articles

Volume
9
Issue
1
Published
Pages
1–139
Articles
28
Sections
6
ISSN
Print - 0975-1483 | Online - 0975-1505
Journal
JYP
EditorialReview ArticleOriginal ArtcileShort CommunicationLetter to the EditorCase Report

In this issue

Editorial

  1. Forum Article

    Let’s not ignore when the patient snores in clinic: an alarming call for oral health care professionals

    Chidambaram Ramasamy, Subrmani Parusuraman

    pp. 1–2 · DOI: 10.5530/jyp.2017.9.1 · Published

    Sleeping well is a fundamental right to any individual to maintain good physical and mental health. If that is so, should we mind when a patient dozes off in the medical units or dental reception? In layman’s terms in ad…

Review Article

  1. Review

    Switching Drugs from Rx to OTC status – A Regulatory Perspective

    Sharanya Sankaran Kartha, Girish Pai Kulyadi, Krishnamurthy Bhat, Muddukrishna Badamane Sathyanarayana

    pp. 3–7 · DOI: 10.5530/jyp.2017.9.2 · Published

    Initially drugs are available for consumption to the public only after con sulting with a healthcare professional and obtaining a prescription for the same. However, to enhance consumer access to a safe and effective dru…

  2. Review

    Perioceutics in the management of Periodontal Disease

    Rajeev Arunachalam, Vini Rajeev, Vaishnavi Vedam, Sivadas Ganapathy, Jawahar Dhanavel

    pp. 8–13 · DOI: 10.5530/jyp.2017.9.3 · Published

    Periodontal disease is an immuno-inflammatory condition involving the tissues that surround and support the teeth. Till date back bone of periodontal treatment is still mechanical removal of plaque and calculus deposits …

  3. Review

    Autoimmune Disorders–Immunopathogenesis and Potential Therapies

    Sivadas Ganapathy, Vaishnavi Vedam, Vini Rajeev, Rajeev Arunachalam

    pp. 14–22 · DOI: 10.5530/jyp.2017.9.4 · Published

    Autoimmune disorders are formed in the body as an outcome of in appropriate immune response against its own tissues. Failure of this immune system to recognize the body’s normal constituents as “self” will result in infl…

Original Artcile

  1. Article

    A Computational Approach to Design Potential Antiviral RNA for 3’UTR Post Transcriptional Gene Silencing of Different Strains of Zika Virus

    M.A Hashem, Moinul Abedin Shuvo, Arifuzzaman a

    pp. 23–30 · DOI: 10.5530/jyp.2017.9.5 · Published

    Background:Zika virus is a flare-up mosquito-borne virus that manifests itself in sporadic human infections with Zika fever. It has a serious affect in pregnant women. Mother transmits Zika virus infection to her infant …

  2. Article

    Morphological and Morphometric Study of Edaravone in Gentamicin-Induced Nephrotoxicity in Sprague Dawley Rats

    Rajavel Varatharajan, Lee Hui Jun, Tan Zhi Kai, Lim Wai Jian, James Anburaj, Venugopal Vijayan

    pp. 31–35 · DOI: 10.5530/jyp.2017.9.6 · Published

    Background:Gentamicin is an antibiotic that exhibits a broad spectrum of activity against microorganisms. Now a days uses of gentamicin are limited due to it potentially induces nephrotoxicity by selective accumulation o…

  3. Article

    Evaluation of Colorectal Cancer (CRC) Epidemiology A Pharmacogenomic Approach

    HimaVyshnavi A M, Lakshmi Anand C, Deepak O M, P K Krishnan Namboori

    pp. 36–39 · DOI: 10.5530/jyp.2017.9.7 · Published

    Background:The population-wise variation in proneness of Colorectal Cancer (CRC) has been studied in the manuscript. A population wise analysis of responsiveness towards colorectal cancer is carried out with genetic, epi…

  4. Article

    Changes in Leptin in Relation to Increased Testosterone Levels Associated with Eurycoma Longifolia Jack (Tongkat Ali) Root Extract Consumption in Male Rats

    Ghasak Ghazi Faisal, Mainul Haque, Ghazi Faisal Najmuldeen, Basma Ezzat Al-Ahmad, Ali Sabri Radeef, Ahmed Ghazi Alattraqchi

    pp. 40–42 · DOI: 10.5530/jyp.2017.9.8 · Published

    Objectives: Eurycoma longifolia jack root extract has been known for its aphrodisiac and anabolic properties. Our study aimed at investigating the effects of this extract on the serum leptin in relation to the well-known…

  5. Article

    Effects of Sulfur, Iron and Manganese Starvation on Growth, β-carotene Production and Lipid Profile of Dunaliella salina

    Saeedeh Shaker, Mohammad Hossein Morowvat, Younes Ghasemi

    pp. 43–46 · DOI: 10.5530/jyp.2017.9.9 · Published

    Objective:Microalgal pharmaceutical biotechnology is mainly dependent on the biomass yield and also the final concentration of the obtained lipids. β-carotene is one of the most precious nutraceuticals, of both preventiv…

  6. Article

    Pharmacists In National Public Health Programs In India: A Pilot Study Highlighting Physicians’ Perceptions

    Siva Prasada Reddy Maddirala Venkata, Peter Kielgast, Ubaidulla Udhumansha, Marja Airaksinen

    pp. 47–54 · DOI: 10.5530/jyp.2017.9.10 · Published

    Background:Community pharmacists could play more potential role when finding ways to allocate effectively limited healthcare resources in primary care in many developing countries, including India. Pharmacists could part…

  7. Article

    Adverse Reactions after Hepatitis B Vaccination: A Retrospective Analysis Using Spontaneous Reports

    M Kalaivani, Shruti Rastogi, V Kalaiselvan, G. N. Singh

    pp. 55–59 · DOI: 10.5530/jyp.2017.9.11 · Published

    Background: Safety of vaccines is more critical because they are used for immunization in children and Hepatitis-B vaccination is included in national immunization schedule for neonates and infants in India. The National…

  8. Article

    Study of Adverse Drug Effects of Antiepileptic Drugs used in Pediatric Patients in a Tertiary care rural Hospital–a Pharmacov igilance Study

    Akanksha Suman, Devesh. D. Gosavi

    pp. 60–64 · DOI: 10.5530/jyp.2017.9.12 · Published

    Objective: To assess the prescription pattern & Adverse Drug Reaction (ADR)) profile of Antiepileptic drug (AEDs) therapy in children of rural population. Materials and Methods: This prospective open label, observational…

  9. Article

    Efficacy of Corticosteroids in Acute Respiratory Distress Syn drome: An Observational Study

    Prabhu Varsha A, Awasthi Shivanshu, Shanavas Rithu, Kunhikatta Vijayanarayana, Thunga Girish, Nair Sreedharan, Acharya Raviraja

    pp. 65–68 · DOI: 10.5530/jyp.2017.9.13 · Published

    Background: Deficits in the treatment options makes Acute Respiratory Distress Syndrome (ARDS) management more challenging. With Involvement of inflammatory pathways, corticosteroid remains a vital choice for ARDS treatm…

  10. Article

    Modulation of Doxorubicin-Induced Cardiotoxicity by Averrhoa bilimbi extract

    Albi Francis, Yogendra Nayak

    pp. 69–77 · DOI: 10.5530/jyp.2017.9.14 · Published

    Introduction: Severe cardiotoxicity limits the use of doxorubicin in cancer treatment. Doxorubicin toxicity involves the generation of reactive oxygen species (ROS) and hence several antioxidants and plant products have …

  11. Article

    Development of Nanoparticulate Hydrogel Loaded with Crossandra infundibuliformis Extract

    Divya Jyothi, Sneh Priya, Jainey P James

    pp. 78–82 · DOI: 10.5530/jyp.2017.9.15 · Published

    Objective:Present study is aimed at formulation of hydrogel containing PLGA nanoparticles loaded with of Crossandra infundibuliformis (CI) extract. Leaf extract of Crossandra infundibuliformis has been reported to posses…

  12. Article

    Effect of Arginine on IL-6, IL-17 and TGF-β levels in high-fat Diet-Induced Hypercholesterolemia Rat

    Eryati Darwin, Eka Fithra Elf, Dachriyanus d

    pp. 83–86 · DOI: 10.5530/jyp.2017.9.16 · Published

    Objective: The aim with the present study was to determine that arginine affect to the level of IL-6, IL-17 and TGF-β in high-fat diet-induced hyper cholesterolemia in rats. Material and Methods: Male Wistar rats in eigh…

  13. Article

    Application of 32 Factorial D-Optimal Design in Formulation of Porous Osmotic Pump Tablets of Ropinirole; An Anti-Parkinson’s Agent

    Anoop Narayanan V, Praveena George, Dhamelia Akshay L

    pp. 87–93 · DOI: 10.5530/jyp.2017.9.17 · Published

    Objective:In the present study, our objective was to develop porous osmotic pump tablets of an anti-Parkinson’s agent, ropinirole. It also aimed to demonstrate the applicability of factorial designs and there by a statis…

  14. Article

    Use of Okra Mucilage and Chitosan Acetate in Verapamil Hydrochloride buccal patches development; In vitro and Ex vivo Characterization

    Raja Navamanisubramanian, Raghunandan Nerella, Chamundeeswari D, Shanmuganathan Seetharaman

    pp. 94–99 · DOI: 10.5530/jyp.2017.9.18 · Published

    Objective:Transmucosal buccal drug delivery could be an alternative for oral administration for systemic delivery of Verapamil Hydrochloride (VH), as it has low bioavailability 20 - 35 % due to its extensive first pass m…

  15. Article

    Mucoadhesive Film Embedded with Acyclovir Loaded Biopolymeric Nanoparticles: In vitro Studies

    Anroop Balachandran Nair, Abbas Ahmed Al-ghannam, Bandar Essa Al-Dhubiab, Azza Ali Hasan

    pp. 100–105 · DOI: 10.5530/jyp.2017.9.19 · Published

    Objective:The efficiency of acyclovir, a potent antiviral agent, is mainly limited by its low permeability.The purpose of this investigation was to formulate and assess nanoparticle impregnated buccal films to improve ac…

  16. Article

    A novel and Rapid LC–MS/MS assay for the Determination of Mycophenolate and Mycophenolic Acid in Human Plasma

    Rambabu Maddela, Nageswara Rao Pilli, Srinubabu Maddela, Chalapathi Rao Pulipati, Srinivasa Rao Polagani, Ajitha Makula

    pp. 106–113 · DOI: 10.5530/jyp.2017.9.20 · Published

    Objective: The main goal of this research was to develop a simple, rapid and sensitive liquid chromatography/tandem mass spectrometry (LC–MS/ MS) method for the simultaneous quantification of mycophenolate mofetil and my…

  17. Article

    Effect of p53 Codon 72 Polymorphism on Clinical Outcome in Lo cally Advanced Breast Cancer Patients Receiving Anthracycline Based Neoadjuvant Chemotherapy

    Sambasivam Gopinath, Deepak Gopal Shewade, Biswajit Dubashi, Dharanipragada Kadambari, Ananthakrishnan Ramesh, Ramasamy Kesavan

    pp. 114–119 · DOI: 10.5530/jyp.2017.9.21 · Published

    Background: Breast cancer is the second most common cancer in the world after lung cancer and the most common cancer among women. Most of the women exhibit interindividual variation to cytotoxic therapy. It may be due to…

  18. Article

    Capillary Electrophoresis Method Development for Simultaneous Determination of Atorvastatin and Ezetimibe from Solid Dosage Form

    Mahesh Attimarad

    pp. 120–123 · DOI: 10.5530/jyp.2017.9.22 · Published

    Purpose: A simple, rapid, validated capillary zone electrophoresis (CZE) was established for the simultaneous estimation of atorvastatin and ezetimibe from solid dosage form. Method: The separation of both the drugs was …

Short Communication

  1. Communication

    In silico Docking Studies on ATP-Sensitive K+Channel, Insulin Receptor and Phosphorylase kinase Activity by Isolated Active Principles of Stereospermum tetragonum DC

    Bino Kingsley, Sunitha Kumari, Appian Subramoniam, Brindha Pemiah

    pp. 124–126 · DOI: 10.5530/jyp.2017.9.23 · Published

    Background: Stereospermum tetragonum is a medicinal plant that grows throughout tropical parts of Indian sub continent, particularly in sandy soils of river beds in Northern India. S. tetragonum is a potential source of …

  2. Communication

    Bioinsecticide Effect of Pinus merkusii Tree Bark Extract on Aedes aegypti larvae

    Setiawan s, Koerniasari k, Ngadino n, Sri Agus Sudjarwo

    pp. 127–130 · DOI: 10.5530/jyp.2017.9.24 · Published

    Objective:Aedes aegypti is the vector responsible for the transmission of dengue fever, and it is a cosmotropical species that proliferates in the water stagnant areas near the houses.Therefore, it is necessary to find n…

Letter to the Editor

  1. Article

    A Critical view of Pharmacy Education and Practice in Kenya

    Mitchel Otieno Okumu, Francis Okumu Ochola, Mary Atieno Onyango

    pp. 131–132 · DOI: 10.5530/jyp.2017.9.25 · Published

    The importance of the pharmacy practitioner to the healthcare team in general and to the patient in particular is under serious threat in Kenya. T he perception that the exclusive role of the pharmacist is to dispense me…

Case Report

  1. Article

    5-Fluorouracil induced severe febrile neutropenia and death

    Vinodkumar Mugada, Haribabu Ramineni, Dharmareddy Padala

    pp. 133–134 · DOI: 10.5530/jyp.2017.9.26 · Published

    5-Fluorouracil (5-FU) induced severe febrile neutropenia is a serious threat which, if unnoticed may lead to death. We present here a case of 46 years old female patient who suffered severe febrile neutropenia and finall…

  2. Article

    Hyperlipoproteinemia(a) and Hyperhomocysteinemia in an Young Female with Cerebrovascular Accident

    Krishna Sen, Anjan Adhikari, Moumita Ray

    pp. 135–136 · DOI: 10.5530/jyp.2017.9.27 · Published

    Background: Hyperhomocysteinemia is a recognized cause of cerebro vascular accident in young, in the Indian subcontinent population. But high lipoprotein(a) is not so much common and though associated with atherogenesis,…

  3. Article

    Proton Pump Inhibitor-induced Hypersensitivity Reaction: A Case Report

    Anjan Adhikari, Rania Indu, Moumita Ray, Sangita Bhattacharya, Rahul Biswas, Anup Kumar Das

    pp. 137–139 · DOI: : 10.5530/jyp.2017.9.28 · Published

    Introduction:Drug induced allergy or hypersensitivity reaction is of great clinical significance in therapeutics. Various factors may contribute like age, genetic composition, disease of the patients and the types of dru…