Volume 59, Issue 1S

Gorantla Naresh Babu, M Menaka, Hindustan Abdul Ahad

pp. s243–s255 · DOI: 10.5530/ijper.20256428 · 2025

Introduction Mucoadhesive microspheres for drug delivery are retained in the stomach for an extended period for localized drug release and effect. Objectives This research aims to explore the mucoadhesive properties of A…

Yanping Li, Suresh Kumar, Hao Peng, Lihu Zhang

pp. s256–s263 · DOI: 10.5530/ijper.20250167 · 2025

Background Klebsiella pneumoniae is a ubiquitous opportunistic pathogen that poses a significant threat to hospitalized patients by causing a wide range of infections. The alarming increase in clinical resistance to all …

Dhanraj Patil, Kiran Shelar, Gayatri Korade, Prince Rituraj, Rushika Mhaske, Midhun Mathew Kizhakethil

pp. s264–s273 · DOI: 10.5530/ijper.20254916 · 2025

Background: Patient counselling is recognized as an integral component of healthcare services, providing essential guidance to patients. However, it has been observed that in India, practical attendance of designated pat…

Patel Vishva Shailesh kumar, Kapupara Pankaj Popatlal

pp. s274–s282 · DOI: 10.5530/ijper.20253781 · 2025

Aim This Study aimed to develop a stable, efficient, and reproducible RP-HPLC method that indicates stability, for the simultaneous determination of Remogliflozin Etabonate and Metformin HCl. Materials and Methods The Se…

Vighnesh Pradeep Nalawade, Faiz Hussain Sayyed, Sonali Ramgopal Mahule, Pandurang Maruti Chavhan, Nitin Rathod

pp. s283–s291 · DOI: 10.5530/ijper.20256210 · 2025

Background A quantifiable method has been developed to determine the key starting material, its intermediates and known impurities in the presence of Imipramine Hydrochloride in the final API of a synthetic laboratory sa…

Paduri Amani, Narender Malothu, Chamakuri Kantlam, Chakravarthi Guntupalli

pp. s292–s299 · DOI: 10.5530/ijper.20256853 · 2025

Aim This study introduces a novel simultaneous analytical quantification of Lopinavir (LPV) and Ritonavir (RTV) in drug products by using LC-MS/MS. Materials and Methods The present study were carried out on Acquity™ LC …

Pydi Geetha Bhavani, Durairaj Akila Devi

pp. s300–s311 · DOI: 10.5530/ijper.20250020 · 2025

Introduction Prazosin is a quinazoline derivative and a selective antagonist of the α1 adrenergic receptor. The atomic structure is C19H21N5O4 and its molecular weight is 383.41 Prazosin is a helpful medication for manag…

Vipul M. Patil, Harinath N. More

pp. s312–s322 · DOI: 10.5530/ijper.20256457 · 2025

Background Inflammation, a complex biological process mediated by arachidonic acid metabolites, plays a crucial role in various diseases like arthritis, psoriasis and neurodegenerative disorders. The Cyclooxygenase (COX)…

R. Manikandan, K. Devi, D. Rajalingam

pp. s323–s332 · DOI: 10.5530/ijper.20256349 · 2025

Aim To carry out Synthesis and Evaluation of novel 2, 5-substituted Pyrazolonefor Neuroprotective Potential in SH-SY5Y Human Neuroblastoma Cells. Materials and Methods Alzheimer’s Disease (AD) has become a serious public…

Yasmin Hamid Momin, Shailaja Prakash Desai, Pranali Ananda Chavan

pp. s333–s340 · DOI: 10.5530/ijper.20255768 · 2025

Aim Factor Vila is a glycosylated disulfide-linked heterodimer that belongs to the serine protease family involved in the coagulation process. Inhibition of factor Vila is one of the crucial targets for novel anticoagula…

Fatima Ulya Yürük, Güldem Mercanoğlu, Gülrû Yüksel, Zeynep Yeşim Ay, Nazlıcan Uçar, Songül Tezcan

pp. s341–s346 · DOI: 10.5530/ijper.20255958 · 2025

Background As clinical responsibilities continue to grow, it becomes essential for clinical pharmacists to acquire advanced competences, such as patient monitoring, patient-specific drug therapy design and evaluation, an…

Aruna Dhamija, Shilpa Tandon, Sachit Paliwal, Parul Agrawal

pp. s347–s354 · DOI: 10.5530/ijper.20255436 · 2025

Aim/Background The purpose of the current study is to understand the COVID-19 pandemic as the greatest psychological challenge that humankind has ever faced. COVID-19 started in China in December 2019 and has conquered t…

Mohanraj Rathinavelu, Veeramani Ganesan, Mallela Vijaya Jyothi

pp. s355–s360 · DOI: 10.5530/ijper.20255423 · 2025

Background The “more-is-better” antimicrobial prescribing philosophy besides resistance is a significant contributor to suffering and death in children. Only a few nations have given comprehensive and comparable statisti…

Chaoyou Zhou, Qiongshan Li, Yinjian Zhou, Zhuangzhuang Xu, Yan Jin

pp. s361–s366 · DOI: 10.5530/ijper.20255955 · 2025

Background “Pre-eclampsia” is one of the most dangerous pregnancy complications, increasing the risk of both the mother and the baby dying prematurely. Because there have been conflicting findings on whether folic acid c…

Aryaa Ankalikar, Agadi Hiremath Viswanthaswamy, Vaishali Undale

pp. s367–s374 · DOI: 10.5530/ijper.20254509 · 2025

Background Obesity is typically characterized by excess deposition of adipose tissue. Along with dietary management, increase in physical activity, lifestyle modification, surgical intervention, drug treatment is also av…

Munther Abduljaleel Muhammad-Ali, Ekhlas Qanber Jasim, Abeer Issa Mohammed

pp. s375–s389 · DOI: 10.5530/ijper.20255394 · 2025

Aim: The objective of this study is synthesis of 1,2,4-triazole derivatives, evaluation there in vitro antimicrobial activity and showing the molecular docking. Materials and Methods: Two series of 5-alkylthio-3-aryl-4-p…

Prabhudatta Mohapatra, Durga Madhab Kar, Karmajeet Rath, Abhisek Pal

pp. s390–s396 · DOI: 10.5530/ijper.20255065 · 2025

Aim/Background Our objective is to describe the patterns of prescribing drug combinations and lifestyle modification in which therapy focuses on SGLT2 and DPP4 inhibitors and dose variation according to the blood glucose…

Joy Das, Utpal Bhui, Shreya Chowdhary, Subhajit Sarkar, Indra Kumar Ghoshal, Soumyadip Nayak, Rahul Bishayee, Navneet Khurana, Bimlesh Kumar, Neha Sharma

pp. s1–s15 · DOI: 10.5530/ijper.20250179 · 2025

Neurodegenerative diseases constitute a pressing global health challenge, characterized by the gradual loss of neuronal function and structure, leading to cognitive impairment and motor deficits. Biomarkers play a crucia…

Dilend Patle, Narendra Pratap Singh Sengar

pp. s16–s24 · DOI: 10.5530/ijper.20255296 · 2025

Background This comprehensive review highlights the importance of bio-conjugated metallic complexes in drug design, particularly in the field of metallo-pharmaceutical science. The review emphasizes the need for biologic…

Sadhana Sharma, Chandana Majee, Rupa Mazumder, Avijit Mazumder, Pankaj Kumar Taygi, Sachin Kumar Singh

pp. a25–a45 · DOI: 10.5530/ijper.20250270 · 2025

Oxadiazoles and their derivatives represent a significant class of organic compounds, wielding profound implications in both the realms of medicinal science and heterocyclic rings housing oxygen and nitrogen atoms, has g…