Volume 59, Issue 4

Hua Li, Lin Liu, Mao Li, Yuhong Sun, Minghua Liu

pp. 1238–1244 · DOI: 10.5530/ijper.20257182 · 2025

Pharmacology laboratory teaching includes basic animal handling, basic experiments, integrated experiments, designed experiments and scenario-based discussions between doctors and patients. The problems in the evaluation…

Antony Sebastian Johnson, Balamuralidhara Veeranna, Saba Maanvizhi

pp. 1245–1253 · DOI: 10.5530/ijper.20250523 · 2025

The Food and Drug Administration (FDA) known for its rigorous regulatory oversight, conducts routine inspections in the pharmaceutical industry, utilizing Form 483 to highlight observed non-compliances. Inadvertent breac…

Dhakane Sumeet, Jain Rahul, Joshi Neeta

pp. 1254–1261 · DOI: 10.5530/ijper.20251071 · 2025

Lyophilization, often known as freeze-drying, is a critical process widely utilized in pharmaceuticals and biotechnology to preserve sensitive materials. This paper examines key parameters influencing lyophilization qual…

Purushottam Gangane, Nikita Raulkar, Nikita Wagh, Vijaya Rabade, Harigopal Sawarkar

pp. 1262–1271 · DOI: 10.5530/ijper.20253959 · 2025

In 1987 James Parkinson first describes Parkinson's Disease (PD) as a neurological syndrome. Over ten million people worldwide suffer with PD. The exact quantity of people suffered with PD is difficult to calculate becau…

Li Ming Wang, Yan Chun Wang, Shan Shan Li, Ying Jin

pp. 1272–1276 · DOI: 10.5530/ijper.20255653 · 2025

Background: Two-stage collaborative exams have been proven to improve students’ performance and enhance students’ learning efficiency. However, there is no quality study on students' perception of two-stage exams through…

Weiguo Hu, Zi Ye, Chou Chen, Wei Chen, Chan Li, Haijun Zhou, Ruiyang Chen

pp. 1277–1284 · DOI: 10.5530/ijper.20253776 · 2025

Aim/Background: This study investigated the relationship between thinking styles and classroom management among teachers at X (anonymous) Vocational College of China during the academic year 2021-2022. Materials and Meth…

Khushboo Katharotiya, Dhaval Katharotiya, Lalit Lata Jha

pp. 1285–1292 · DOI: 10.5530/ijper.20250371 · 2025

Objectives: The research aims to enhance understanding of aquasome preparation, offering insights into optimizing formulations for potential applications in drug delivery systems. Materials and Methods: Aquasomes compose…

Prashant Nayak, Rompicherla Narayana Charyulu

pp. 1293–1304 · DOI: 10.5530/ijper.20257236 · 2025

Background: Lung cancer continues to pose a major challenge to global health, with limited therapeutic options and high mortality rates. One factor that contributes to this is the overexpression of BCL2, an anti-apoptoti…

Yashowardhan Raut, Kishori Prasanna Sutar, Shivaraj Hooli, Gautam Naik, Vinayak Udagatti

pp. 1305–1311 · DOI: 10.5530/ijper.20251264 · 2025

Objectives: The goal of this work was to formulate a stable naringenin-loaded cubosomal in situ gel to improve naringenin absorption into the brain by direct nose-to-brain transfer. Materials and Methods: This investigat…

Mukesh P. Ratnaparkhi, Swati Dattatray Kshirsagar

pp. 1312–1322 · DOI: 10.5530/ijper.20251073 · 2025

Objectives: To develop and evaluate a Propolis-Loaded Nanosponge (PLN)-based topical gel with potential anti-inflammatory, antifungal and antibacterial activities. Materials and Methods: PLNs were prepared using the emul…

Shivraj Popat Jadhav, Prashant Kumar Dhakad, Tapasvi Gupta, Ritu Gilhotra

pp. 1323–1333 · DOI: 10.5530/ijper.20250282 · 2025

Introduction: Iloperidone is categorised as an antipsychotic drug and is used to treat schizophrenia. Iloperidone belongs to the Biopharmaceutics Classification System class II due to its low water solubility. Objectives…

S K Kavitha, Ali Mohammad, Bharathi D R, Yogesh H S

pp. 1334–1346 · DOI: 10.5530/ijper.20250803 · 2025

Aim: Nanotechnology is pivotal in the pharmaceutical industry, significantly augmenting drug properties and formulations. It enhances drug stability and controlled release, providing precise control over drug delivery sy…

Mani Uppada, Srinivasa Rao Yarraguntla, Sai Sri Vastav Mylavarapu, Persis Joni Kappala, Satyalakshmi Siragam

pp. 1347–1356 · DOI: 10.5530/ijper.20257306 · 2025

Background: The aim of this study was to explore the potential of repurposing the anti-HIV drug Efavirenz (EFZ) in combination with Curcumin (CUR) for cancer therapy. EFZ is an antiviral drug and selective anti-HIV drug …

Soma Uday Kumar Reddy, Divya Jyothi, Krishna Kana Veetil, Shreya Shreya, Rokeya Sultana, Sneh Priya

pp. 1357–1365 · DOI: 10.5530/ijper.20250520 · 2025

Objectives: Microwave-Assisted Extraction (MAE) has emerged as a promising technique for the extraction of bioactive compounds from plant materials due to its efficiency and reduced processing time. In the present study,…

Nan Gong, Huimin Chang, Mengchao He, Xiaohong Zhang, Wenjing Li

pp. 1366–1374 · DOI: 10.5530/ijper.20251122 · 2025

Background: Allergic Rhinitis (AR) is a prevalent inflammatory disorder of the nasal mucosa, often triggered by an IgE-mediated immune reaction to allergens. The underlying cause of AR can be attributed to the genetic pr…

Li Jiang, Tao Zhang, Fangtao Yan, Jian Shen, Abdullah A. Alarfaj, Abdurahman Hajinur Hirad

pp. 1375–1384 · DOI: 10.5530/ijper.20251124 · 2025

Background: Acute Lung Injury (ALI) is a severe, serious condition characterized by the development of pulmonary edema, hypoxemia and respiratory distress. Objectives: The current work was intended to disclosing the bene…

Abdulaziz Asiri

pp. 1385–1394 · DOI: 10.5530/ijper.20251924 · 2025

Background: Inhibiting Cyclin-Dependent Kinase 2 (CDK2) holds significant therapeutic potential for lung cancer by targeting a critical regulator of the cell cycle. CDK2 inhibition halts cancer cell proliferation, induce…

Yan Tao, Nan Cai, Juxia Zhang, Yaoping Zhao, Yan Zhou, Pengfei Liu

pp. 1395–1407 · DOI: 10.5530/ijper.20251146 · 2025

Background: The nociceptive pain is a fundamental sensory response that works as a crucial protective mechanism for the human body. Chronic pain constitutes a substantial public health issue, impacting millions of indivi…

Pradeep Kumar Mavinatop Ramanagouda, Santosh Basavaraj Patil, Sangameshwar Girimallappa Halkavatagi, Pankaj Kumar, Gupta Dheeraj Rajesh, Manisha Kuvalekar

pp. 1408–1418 · DOI: 10.5530/ijper.20255884 · 2025

Aim/Background: Traditionally, Phaseolus vulgaris is used to treat common diseases. However, the affinity of its phytocompounds with proteins involved in the pathogenesis of Tuberculosis (TB) has not yet been illuminated…

Jing Xu, Fei Wang, Minjuan Zhang, Maoyuan Chen, Ke Zhao, Yang Liu, Dong Li

pp. 1419–1428 · DOI: 10.5530/ijper.20251256 · 2025

Background: Managing wounds in diabetic patients requires specialized approaches due to their unique healing challenges. Diabetic wounds, particularly Diabetic Foot Ulcers (DFUs), often exhibit delayed healing, increased…