Volume 59, Issue 3S

Saravanakumar Kasimedu, UshaPriya Halapaka Selvam, Keerthishree Suresh Sharma, Navina Sreenivasan Arrivur, Niranjan Babu Mudduluru

pp. s776–s787 · DOI: 10.5530/ijper.20251674 · 2025

Nanotechnology is a promising technology in the creation of novel strategies in the field of the healthcare domain. Nano distribution of pharmaceuticals emerging new features for enhanced targeted drug delivery in the di…

Pooja Harakal, Nilesh Kulkarni, Suvarna Gore, Komal Khade, Shashikant Dhole

pp. s788–s801 · DOI: 10.5530/ijper.20255950 · 2025

Oral administration is the best way to administer both traditional and novel drugs because it decreases patient non-compliance and can also relieve the pain and discomfort associated with parenteral preparations. However…

Aman Shrivastava, Sumeet Dwivedi, Shiv Narayan, Abhishek Dwivedi, Jailani Shiekmydeen, Amit Anand, Arvind Kumar Tripathi, Kuldeep Singh

pp. s814–s824 · DOI: 10.5530/ijper.20250849 · 2025

The increasing prevalence of insulin resistance disorders, including type 2 diabetes and metabolic syndrome, underscores the urgent need for advanced diagnostic and therapeutic strategies. This review aims to explore the…

Mayur Popat Sawant, Gitanjali Sambhajirao Deokar

pp. s802–s813 · DOI: 10.5530/ijper.20257267 · 2025

The pharmaceutical and cosmetics industries, as well as the domains of research and clinical medicine, have all benefited from the advent of Solid Lipid Nanoparticles (SLN) as a promising new drug delivery technique. The…

Mehmet Kalayı, Arkan Yashar Barbar, Buket Aksu

pp. s825–s836 · DOI: 10.5530/ijper.20256989 · 2025

Aim/Background The objective of this research is to develop and enhance the formulation of aripiprazole rapid disintegrating tablets utilizing the Quality by Design (QbD) methodology. Materials and Methods A full factori…

Nagella Raveendra Babu, Rajendra Awasthi, Dhawal Ankola, Dheeraj Nagpal

pp. s837–s850 · DOI: 10.5530/ijper.20251074 · 2025

Aim: The current article aimed to synthesize new HPMC derivative polymers by esterification method. Background: 2 most common causes of drug candidate failures are a lack of effectiveness and PK/bioavailability issues. V…

Babita Agarwal, Sachin Jagdale, Tejaswini Kanakdande, Rushikesh Shinde

pp. s849–s862 · DOI: 10.5530/ijper.20251113 · 2025

Objectives: Emulgel, known for their unique combination of properties from both emulsions and gels, have attracted significant interest from the pharmaceutical and cosmetic industries for their versatility and usefulness…

Lakshmi Devi Gottemukkula, Raghuveer Pathuri, Sunitha Sampathi

pp. s863–s873 · DOI: 10.5530/ijper.20255690 · 2025

Background: Dolutegravir (DTG) is an integrase strand transfer inhibitor that prevents the integration of viral DNA into host cell DNA, which is one of the key phases in the life cycle of HIV, preventing the virus from m…

Jayadev Hiremath, Nimbagal Raghavendra Naveen, Prakash Goudanavar, Girish Meravanige, Santosh Fattepur, Rashed M. Almuqbil, Bandar Aldhubiab, Sreeharsha Nagaraja

pp. s874–s880 · DOI: 10.5530/ijper.20252845 · 2025

Background: Dolutegravir Sodium (DTG) is a poorly soluble antiretroviral drug that will find it difficult to achieve oral bioavailability. Preformulation and screening of excipients are mandatory as a stepping stone in f…

Rutuja Aher, Ritesh Karmarkar, Yash Bachhav, Kunal Bhambar, Poonam Patil

pp. s881–s889 · DOI: 10.5530/ijper.20251391 · 2025

Background: Background of the present research study was to investigate shea butter as absorption base and nerolidol as permeability enhancer for transdermal delivery of diclofenac diethylamine. Hypothesis: In present st…

Aiman Rabiya, Mohamed Hassan Dehghan

pp. s890–s901 · DOI: 10.5530/ijper.20252275 · 2025

Objectives: This study aimed to develop a novel bi-compound pharmaceutical capsule containing nifedipine gastro-retentive floating microspheres and telmisartan immediate-release solid dispersions using a Quality by Desig…

Sagar Koirala, Preethi Sudheer, Litha Thomas, Ashwini Alur, Johnsi Srinivasan

pp. s902–s909 · DOI: 10.5530/ijper.20256572 · 2025

Background: The current study aimed to design dorzolamide hydrochloride nanoparticle (NP)-laden contact lenses to control drug release for the effective management of glaucoma. Materials and Methods: Ionotropic gelation …

Seyyedeh Mahdokht Maddah, Golaleh Mostafavi, Masoud Vaali, Ehsan Ranjbar

pp. s910–s920 · DOI: 10.5530/ijper.20255499 · 2025

Aim/Background: Cancer is the second deadliest disease worldwide. Medicinal plants have been recognized for their cytotoxic and antitumor properties. This study aimed to assess the potential anticancer effects of the hyd…

Ade Dwi Pratiwi, Jekson Martiar Siahaan, Endy Juli Anto

pp. s921–s929 · DOI: 10.5530/ijper.20250752 · 2025

Background: This study investigated the effect of rosella flower petal (Hibiscus sabdariffa L.) ethanol extract gel on incision wound healing in a rat model of diabetes mellitus. Wounds are skin disorders that can be cau…

Afaf Salim Alwabli, Mohammed Balubaid, Mohammed Tarique

pp. s930–s944 · DOI: 10.5530/ijper.20251313 · 2025

Background Dengue Virus (DENV) infection poses a formidable global health threat, spanning from mild breakbone fever to severe conditions such as dengue hemorrhagic fever and dengue shock syndrome. The NS5-MTase enzyme a…

Ahmed Ridha El Ouederni, Rania Omrani, Sonia Taktouk, Yasmine El Ouederni, Nour El Ouederni, Aida Katar

pp. s945–s949 · DOI: 10.5530/ijper.2025489 · 2025

Background: This paper focuses on an experimental investigation of an indirect solar dryer, specifically designed for drying aromatic and medicinal plants. Objectives: The purpose of this study is to utilize solar energy…

Koppala Rakesh Viswa Sai Chaitanya, Sridevi Korimelli, Supriya Reddy Gaddam, Manuri Kavya, Ramya Chandupatla, Venna Rajeswari Surya Anusha

pp. s950–s960 · DOI: 10.5530/ijper.20250416 · 2025

Background: Cognitive impairment is a pervasive and perplexing concern that transcends the boundaries of various neuropsychiatric disorders like schizophrenia and Alzheimer’s. As research continues to unravel the intrica…

Sushmita Semwal, Neeraj Kumar, Bhuwan Chandra Joshi, Pankaj Budhlakoti

pp. s961–s968 · DOI: 10.5530/ijper.20251207 · 2025

Background: Cinnamomum tamala(Lauraceae), commonly known as Tejpaat or Bay leaves, find application in foods, along with traditional uses for curing a number of ailments. The objective of the current study was to investi…

Umar Farooq Mir, Deepak Kumar Jha, Sandipan Chatterjee, Harshitha Nagaraj, Mehdi Fathima, Saroj Kumar Sah

pp. s969–s977 · DOI: 10.5530/ijper.20251234 · 2025

Objectives: The study aimed to evaluate the nephroprotective effects of the methanolic extract of Leucaena leucocephala seeds against Cisplatin-Induced Nephrotoxicity (CIN) in rats through biochemical, antioxidant and hi…

Saravanan Muthaiah, Seema Mudhol, Muthukumar Serva Peddha

pp. s978–s988 · DOI: 10.5530/ijper.20256700 · 2025

Background: The secondary metabolites from natural herbs are exploited to treat various human ailments. The present study aimed to investigate the ameliorative effect of the methanolic extract of Cassia auriculata (C. au…