Volume 2, Issue 3

Ambikanandan Misra

pp. 213–215 · DOI: 10.4103/0975-1483.66788

The article begins with the abstract, which is summary of the research work. It is a concise and focused representation of research work indicating the aim of the study, the methods used, results and major findings as a …

Koland M, Sandeep VP, CharyuluCharyulu NR

pp. 216–222 · DOI: 10.4103/0975-1483.66790

Ondansetron hydrochloride, a 5 HT3 antagonist is a powerful antiemetic drug which has oral bioavailability of 60% due to hepatic first pass metabolism and has a short half-life of 5 h. To overcome the above draw back, th…

Swapna N, Jithan AV

pp. 223–228 · DOI: 10.4103/0975-1483.66792

The aim of this study was to prepare zopiclone-loaded polycaprolactone microspheres by emulsion solvent evaporation technique with different drug-to-carrier ratios {MP 1 (1:1), MP 2 (1:2), MP 3 (1:3), and MP 4 (1:4)}, ch…

Sateesha SB, Rajamma AJ, Narode MK, Vyas BD

pp. 229–233 · DOI: 10.4103/0975-1483.66793

The matrix tablets of diltiazem hydrochloride were prepared by direct compression using hydroxypropyl methyl cellulose (HPMC) and various amounts (2.5%, 5.0%, 10% and 20%) of citric acid, malic acid and succinic acid. Th…

Remya KS, Beena P, Bijesh PV, Sheeba A

pp. 234–239 · DOI: 10.4103/0975-1483.66794

The present work was aimed at formulation development, evaluation and comparative study of the effects of superdisintegrants in Cefixime 50 mg oral disintegrating tablets. The superdisintegrants used for the present stud…

Bhoyar PK, Biyani DM, Umekar MJ

pp. 240–246 · DOI: 10.4103/0975-1483.66796

Ondansetron hydrochloride is an intensely bitter antiemetic drug used to treat nausea and vomiting following chemotherapy. The purpose of the present work was to mask the taste of ondansetron hydrochloride and to formula…

Shah S, Pandya S, Bhalekar MR

pp. 247–251 · DOI: 10.4103/0975-1483.66799

Ondansetron is a serotonin 5HT3 antagonist; anti-emetic drug. Bitter taste of the ondansetron is a major problem in ensuring patient compliance. The study was designed to formulate tasteless complexes of ondansetron with…

Jayalakshmi S, Patra A, Wahi AK

pp. 252–254 · DOI: 10.4103/0975-1483.66800

Luffa echinata Roxb., commonly known as Bindal in Hindi is used for its hypoglycemic activity in the indigenous system of medicine. No pharmacognostical study on stem is reported in the literature till date; therefore, i…

Sharma U, Sahu RK, Roy A, Golwala DK

pp. 255–260 · DOI: 10.4103/0975-1483.66803

Stephania hernandifolia (Menispermaceae) is a medicinal plant, used by herbalists for treating various diseases, one of which is diabetes mellitus, in Darjeeling. However, its antidiabetic activity has not been scientifi…

Ali N, Shah SWA

pp. 261–264 · DOI: 10.4103/0975-1483.66805

Objective:To study the possible effects of methanolic extract of fruits of Tamarindus indica on rabbit’s jejunum preparations. Materials and Methods:The study was carried out on rabbit’s jejunum preparations. Methanolic …

Kirana H, Srinivasan BP

pp. 265–268 · DOI: 10.4103/0975-1483.66806

Significant depletion of glutathione (GSH-reduced form) was observed in type 2 diabetes due to oxidative stress. Hence the present study was aimed to investigate a drug which restores GSH along with its anti-diabetic act…

Adepoju GKA, Adeyemi T

pp. 269–272 · DOI: 10.4103/0975-1483.66808

Aim:Citrus aurantifolia (Family Rutaceae) is commonly known as a familiar food and medicine, and s therapeutic effectiveness in a variety of diseases has been suggested in traditional medicine. Various complementary and …

Nannapaneni DT, Gupta Atyam VSSS, Reddy MI, Sarva Raidu Ch

pp. 273–279 · DOI: 10.4103/0975-1483.66809

The synthesized benzimidazoles compounds were prepared from the condensation reaction between o-Phenylenediamine and various carbonyl compounds, in the presence of ammonium chloride as a catalyst. Ammonium chloride is a …

Attimarad M

pp. 280–283 · DOI: 10.4103/0975-1483.66787

The objective of the study was to develop a high performance liquid chromatography (HPLC) method using ultra violet (UV) detection for the determination of flavoxate HCl in bulk and solid dosage forms by using ibuprofen …

Patel KM, Patel CN, Panigrahi B, Parikh AS, Patel HN

pp. 284–288 · DOI: 10.4103/0975-1483.66789

Three simple and sensitive visible spectrophotometric methods (A, B, and C) have been developed for the quantitative estimation of mesalamine in bulk drug and pharmaceutical dosage forms. Methods were based on the format…

Joshi HR, Patel AH, Captain AD

pp. 289–296 · DOI: 10.4103/0975-1483.66791

Two methods are described for determination of Doxophylline in a solid dosage form. The first method was based on ultraviolet (UV)-spectrophotometric determination of the drug. It involves absorbance measurement at 274 n…

Krishna Veni N, Surya Devi M, Rubini MF, Vishalini M, Pradeepa YJ

pp. 297–300 · DOI: 10.4103/0975-1483.66795

A simple, fast, specific, and precise high-performance thin layer chromatography method has been developed for the estimation of monosodium l-glutamate (MSG) in food products. Aluminum plates precoated with silica gel 60…

Mahajan R, Singh NR, Singh J, Dixit A, Jain A, Gupta A

pp. 301–305 · DOI: 10.4103/0975-1483.66797

Objective:In the last 30 years, concepts in pharmacology have moved from Essential Medicines (EM) to P-drugs via the Rational Use of Medicines (RUM), but no structured study has evaluated the level of understanding among…

Abay SM, Amelo W

pp. 306–310 · DOI: 10.4103/0975-1483.66798

The study was aimed at assessing the magnitude and factors of self-medication among medical, pharmacy, and health science students of GCMHS (Gondar College of Medicine and Health Sciences). A cross-sectional study with t…

Ali N, Shah SWA, Khan J, Rehman S, Imran M, Hussian I, Shehbaz N, Jamshed H, Khan S

pp. 311–314 · DOI: 10.4103/0975-1483.66801

A total of 856 diabetic patients were evaluated for pharmacotherapy-based problems like for possible drug interactions, adverse drug reactions, and other mismatches, if any. Poor correlation between the advised insulin t…