Volume 3, Issue 4

Jishnu V, Prabhakaran R, Gilhotra RM

pp. 259–266 · DOI: 10.4103/0975-1483.90233

The aim of the present investigation was to prepare extended release film coated matrix tablets of cephalexin using binary mixture of two grades of hydrophilic polymer, hydroxypropyl methyl cellulose (HPMC), by direct co…

Pandit V, Gorantla R, Devi K, Pai RS, Sarasija S

pp. 267–274 · DOI: 10.4103/0975-1483.90234

Pioglitazone, a class II Biopharmaceutical Classification System drug having poor water solubility and slow dissolution rate may have a negative impact on its subtherapeutic plasma drug levels leading to therapeutic fail…

Bhosale UV, Kusum Devi V, Jain N

pp. 275–283 · DOI: 10.4103/0975-1483.90236

Acyclovir is an antiviral drug used for the treatment of herpes simplex virus infections, with an oral bioavailability of only 10-20% [limiting absorption in gastrointestinal tract to duodenum and jejunum] and half-life …

Cerqueira GS, Rocha NFM, Almeida JRGS, de Freitas APF, Lima EO, Filho JMB, de Freitas RM, Melo Diniz MFF

pp. 284–286 · DOI: 10.4103/0975-1483.90237

This is the first report about the antibacterial activity of Diplotropis ferrugineaBenth. In this study, the ethanol extract of D. ferrugineawas tested for its antimicrobial activity against strains gram-positive and gra…

Bharath Kumar P, Darlin Quine S, Mari Kannan M

pp. 287–296 · DOI: 10.4103/0975-1483.90239

The present study was designed to evaluate the cardioprotective effects of methanolic extract of Litsea deccanensis (MELD) against isoproterenol-induced myocardial infarction in rats by studying cardiac markers, lipid pe…

Upaganlawar A, Balaraman R

pp. 297–303 · DOI: 10.4103/0975-1483.90241

The present study was designed to evaluate the cardioprotective effects of Lagenaria siceraria fruit juice in isoproterenol-induced myocardial infarction. Rats injected with isoproterenol (200 mg/kg, s.c.) showed a signi…

Talla V, Veerareddy PR

pp. 304–309 · DOI: 10.4103/0975-1483.90242

The aim of the study is to examine the oxidative stress in patients on fluoroquinolones (ciprofloxacin, levofloxacin, gatifloxacin) therapy for complicated urinary tract infections and to correlate with plasma concentrat…

Bhat KI, Sufeera K, Chaitanya Sunil Kumar P

pp. 310–314 · DOI: 10.4103/0975-1483.90243

The reaction of p-bromoanilino acetohydrazide(II) with aromatic aldehydes in alcohol yielded 2-[4-bromo aniline] N-substituted benzylidine hydrazides (IIIa-IIIj), which in presence of yellow mercuric oxide and iodine in …

Arumugam K, Chamallamudi MR, Mallayasamy SR, Mullangi R, Ganesan S, Jamadar L, Ranjithkumar A, Udupa N

pp. 315–321 · DOI: 10.4103/0975-1483.90244

A highly sensitive and selective high performance liquid chromatographic fluorescence detection method has been developed and validated for the quantification of rivastigmine in rat plasma and brain. Protein precipitatio…

Vasantha J, Kannan G, Goud T, Palani T, Vanitha R, Anitha R, Priya JJM

pp. 322–329 · DOI: 10.4103/0975-1483.90245

Paclitaxel is a promising drug in the treatment of different solid tumors. It exhibits nonlinear pharmacokinetics, particularly when administered as a constant rate infusion for shorter duration (e.g., 3 h). Because of t…

Mateti UV, Rajakannan T, Nekkanti H, Rajesh V, Mallaysamy SR, Ramachandran P

pp. 329–333 · DOI: 10.4103/0975-1483.90246

Drug–drug interactions (DDIs) are defined as two or more drugs interacting in such a manner that the effectiveness or toxicity of one or more drugs is altered. DDI in patients receiving multidrug therapy is a major conce…

Jishnu V, Gilhotra RM, Mishra DN

pp. 334–342 · DOI: 10.4103/0975-1483.90248

In this world of specialization and globalization the pharmacy education in India is suffering from serious backdrops and flaws. There is an urgent need to initiate an academic exercise aimed at attaining revamping of cu…

Sreedhar D, Janodia MD, Ligade VS

pp. 343–344 · DOI: 10.4103/0975-1483.90250

Sir, Indian pharmaceutical industry has climbed the ladder to reach third position in terms of volume and fourteenth position in value terms. It is estimated to be worth US$ 4.5 billion at annual growth rate of 8–9%. Ind…

Devi AK

pp. 345–348

Adamu AK see Ahmed TS et al., Ahirwar D see Hade D et al. Ahmed TS, Magaji MG, Yaro AH, Musa AM, Adamu AK. Aqueous methanol extracts of Cochlospermum tinctorium (A. Rich) possess analgesic and anti-inflammatory activitie…

Pooja Sharma

pp. 349–350

A perspective for clinical pharmacy curriculum development and validation in Asian developing nations.