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In this issue
1–20 of 30Original Article
- Article
Gaurav Ranjan, Priyashree Sunita, Pritha Bose, Sugato Banerjee, Shakti P. Pattanayak
pp. 247–255 · DOI: 10.4103/pm.pm_89_22 · 2022
Background: Post‑traumatic stress disorder (PTSD) is a severe chronic psychiatric condition for which currently there is no specific therapy. Translocator protein (18 kDa; TSPO), a critical therapeutic target for treatin…
- Article
Hossam M. Abdallah, Gamal A. Mohamed, Sabrin R. M. Ibrahim, Abdulrahman E. Koshak, Ibrahim Alnashri, Abdullah Alghamdi, Abdulghani Aljohani, Abdulrahman Khairy
pp. 256–260 · DOI: 10.4103/pm.pm_118_21 · 2022
Background: Genus Commiphora (Burseraceae) includes about 150 species of aromatic shrubs located in Africa, India, and the Arabian region. C. gileadensis L. has been used for treating several ailments such as constipatio…
- Article
Tao Zhang, Xiaopeng Sun, Ruiping Fang
pp. 261–266 · DOI: 10.4103/pm.pm_14_21 · 2022
Background: Allergic rhinitis (AR) is the prevalent inflammatory disease in the airway due to allergic reactions in response to numerous allergens. AR is considered as a type‑I allergic condition and proceeded as early‑ …
- Article
Chong Liu, Qiuju Wang
pp. 267–272 · DOI: 10.4103/pm.pm_180_21 · 2022
Background: Chronic use of doxorubicin (DOX) as an anticancer and antineoplastic agent has a chief jeopardy of cardiotoxicity. About 10% of the treated population has logged to cause cardiac damage. Objectives: This stud…
- Article
ZS Siti, Nor Hazwani Ahmad, Shahrul Hamid
pp. 273–280 · DOI: 10.4103/pm.pm_338_21 · 2022
Background: Catharanthus roseus (CR) shows promising anticancer activity. However, there is limited information on its polymeric formulation. Objectives: Therefore, current study aimed to characterize poly(lactic‑co‑glyc…
- Article
Chao Yuan, Peihua Sun, Xin Ge, Minling Xu
pp. 281–285 · DOI: 10.4103/pm.pm_144_21 · 2022
Background: Mammary carcinoma is the most communal carcinoma of higher women mortality. Rehmanniae Radix (RR) a traditional Chinese medicine. Objectives: To examine the anti‑proliferative and anti‑apoptotic effect of RR …
- Article
Amit Manhas, Dipika Goyal, Bharti Biswas, Dipti Tripathi, Pragya Yadav, Singh Abhinav, Shri Krishna, Narender Tadigoppula, Madhu Dikshit, Kumaravelu Jagavelu
pp. 286–295 · DOI: 10.4103/pm.pm_79_21 · 2022
Background and Aim: The present study was undertaken to investigate the potential of ethyl acetate fraction obtained from the fruits of Xylocarpus moluccensis alcoholic extract (CDR‑267‑F018) against cardiac hypertrophy …
- Article
Benjaporn Buranrat
pp. 296–303 · DOI: 10.4103/pm.pm_442_21 · 2022
Background: Cratoxylum formosum (CF) is being used in Asian countries to treat disease and for eating purposes. Objectives: In the present study, the young leaf extract of CF was extracted by distilled water (DW) and 95%…
- Article
Minjie Li, Weiwei Feng, Wenping Zhang, Zhonghui Pang, Shaokun Pei, Lifeng Xia, Qiang Li, Huixiao Li
pp. 304–313 · DOI: 10.4103/pm.pm_450_21 · 2022
Background: Osteoporosis (OP) is a common disorder resulting in bone fragility and fracture. Due to OP, bone mass and microarchitectural bone tissues are damaged, increasing the risk of fracture. Objectives: To determine…
- Article
Anroop B. Nair, Santosh Fattepur, N. Raghavendra Naveen, Prakash Goudanavar, Naga Prashant Koppuravuri, Buduru Gowthami, Mallikarjun Telsang, Riyaz Ali Osmani, Nagaraja Sreeharsha, Mohammed Habeebuddin
pp. 314–320 · DOI: 10.4103/pm.pm_601_21 · 2022
Background: Tragacanth, a natural gum, is frequently used as stabilizer for colloidal systems and as a binder in tablets. Materials from natural sources are in increasing demand to solve the current global environmental …
- Article
Yixing Wang, Xuping Zhang, Jin Zhou, Shilei Xu, Xiaodan Kou, Yuan Cheng
pp. 321–327 · DOI: 10.4103/pm.pm_345_21 · 2022
Background: Astilbin is a flavonoid phytoconstituent extracted from Chinese herb Rhizoma Smilacis Glabrae, a common Chinese food ingredient.Objectives: The present study used astilbin as a model drug to develop food‑base…
- Article
Baozhong Wei, Hongxia Zhu, Kai Wang, Shuangming Liu, Yihui Dai, Danhong Liu, Fengguo Xia, Hua Sun
pp. 328–333 · DOI: 10.4103/pm.pm_54_21 · 2022
Background: Gastric cancer is a malignant tumor of the digestive tract. It is the fifth most common cancer and the third leading cause of cancer death across the world. In this study, we investigated the antitumor and im…
- Article
Jinjin Qin, Bei Wang, Rui Li, Fang Wang, Yan An, Chenyuan Cao
pp. 334–340 · DOI: 10.4103/pm.pm_146_21 · 2022
Background: In recent years, the morbidity of gestational diabetes (GD) has increased by around 5%–10%, and it now affects around 8%–21% of all births, with around 3%–5% of these women suffering from long‑term diabetes a…
- Article
Potential Role of Tribulus terrestris Fruit Extract in Inhibition of Advanced Glycation End Products
Dinesh Kumar, Nidhi Shah, Khalid M. Al‑Anazi, Mohammad Abul Farah, M. Ajmal Ali, Joongku Lee, Ahmad Ali
pp. 341–347 · DOI: 10.4103/pm.pm_589_21 · 2022
Background: Glycation refers to the interaction between sugars and proteins leading to the production of harmful advanced glycation end‑products (AGEs). Many different diseases such as neurodegenerative, cardiovascular, …
- Article
Dong Yang, Guangfeng Niu, Jie Guo
pp. 348–352 · DOI: 10.4103/pm.pm_257_21 · 2022
Background: Goniothalamin (GTN) is a well‑known styryl lactone that possesses anti‑inflammatory and anticancer properties. In this study, we evaluated the potential of GTN on experimental arthritis based on the complete …
- Article
Pankaj Singh, Yatendra Singh, Sanjeev Kanojiya, Vineeta Tripathi, Dipak Kumar Mishra
pp. 353–359 · DOI: 10.4103/pm.pm_525_21 · 2022
Background: Calotropis gigantea (L.) W.T. Aiton, belonging to the family Apocynaceae, is a source of many bioactive cardiac glycosides. Accumulation of secondary metabolites in plants depends upon various external and in…
- Article
Yawei Shen, Periyannan Velu, Xin Huang, Taoping Dang
pp. 360–365 · DOI: 10.4103/pm.pm_270_21 · 2022
Background: During the past few years, thyroid cancer (TC) has increased in terms of rate of morbidity and mortality. Plant flavonoids have shown positive effect in regulating thyroid tumorigenesis via inhibition of apop…
- Article
Yingying Fan, Ge Ma, Qingyan Guo, Jian Wang, Periyannan Velu
pp. 366–372 · DOI: 10.4103/pm.pm_281_21 · 2022
Background: Cancer development is a sequential process as a result of various cellular adaptation events. Oral cancer (squamous cell carcinoma) is the most predominant variety of head and neck cancer. Betanin (BTN) is is…
- Article
Binghong Hua, Yin Xiao, Fuling Li
pp. 373–377 · DOI: 10.4103/pm.pm_331_21 · 2022
Purpose: In this study, we aimed to investigate the effects of β‑caryophyllene against oxidative stress‑induced apoptosis in the animal model of diabetes. Materials and Methods: Experimental diabetes was induced in the r…
- Article
Yunfan Liu, Yuemei Du, Liping Gao
pp. 378–385 · DOI: 10.4103/pm.pm_354_21 · 2022
Background: Lycium barbarum polysaccharide (LBP) is a water‑soluble polysaccharide extracted from Lycium barbarum. LBP exhibits potential pharmacological activity, including anti‑cancer activities. However, so far, the e…
