Pharmacognosy Magazine · Archive
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In this issue
1–20 of 28Original Article
- Article
Peng-Nian Yew, Yau-Yan Lim, Wai-Leng Lee
pp. 523–531 · DOI: 10.4103/pm.pm_620_18 · 2019
Objectives: This study aimed to scientifically examine porcupine bezoars as a potential anticancer agent and to investigate their principal bioactive constituents. Materials and Methods: The porcupine bezoars were extrac…
- Article
Gabriel Akyirem Akowuah, Jin Han Chin, Siew Wei Yeong, Suk Yen Quah, Mariam Ahmad
pp. 532–537 · DOI: 10.4103/pm.pm_138_19 · 2019
Aim: The objective of the present study was to evaluate the in vitro effect of aqueous extract of Clinacanthus nutans leaves and the juice on the activity of UDP‑glucuronosyltransferase (UGT), cytochrome P (CYP) 3A4, and…
- Article
Cell Growth, Cell Migration Benjaporn Buranrat, Supavadee Boontha
pp. 538–546 · DOI: 10.4103/pm.pm_109_19 · 2019
Objective: Our study purposes to illuminate the inhibition of PN effects on breast cancer cells growth and migration along with its mechanisms. Materials and Methods: The piperine in the young fruit of PN extract was det…
- Article
Jayalakshmi Ramasamy, Ruckmani Kandasamy, Selvamani Palanisamy, Subramanian Nadesan
pp. 547–556 · DOI: 10.4103/pm.pm_647_18 · 2019
Objective: The objective of this study is to optimize the UAE conditions such as ethanol concentration (50%–100%), solvent‑to‑solid ratio (10–50 mL/g), and sonication time (20–60 min) for the extraction of flavonoids and…
- Article
De Ji, Jin‑Chun Qiu, Xiao‑Nan Su, Yu‑Wen Qin, Min Hao, Lin Li, Tu‑Lin Lu, Xiao‑Kun Li, Cheng‑Xi Jiang
pp. 557–567 · DOI: 10.4103/pm.pm_65_19 · 2019
Objective: The main objective of the study is to establish an ultra‑high‑performance liquid chromatography‑tandem mass spectrometry (MS/MS) method to determine the concentrations of five bioactive constituents in rats’ p…
- Article
Ibrahim S. Al Nasr, Waleed S. Koko, Tariq A. Khan, Gamal E. Elghazali
pp. 568–572 · DOI: 10.4103/pm.pm_646_18 · 2019
Aim: In the present study, extracts from the leaves and fruit of Azadirachta indica A. Juss. collected from different areas, along with two other medicinal plants (Argemone mexicana L. and Xanthium brasilicum Vell.) with…
- Article
Qing Luo, Kang Hu, Fang Chen, Feng‑Jiao Gan, Yuan‑Xiu Leng, Xu‑Mei Chen, Su‑Hong Sun
pp. 573–578 · DOI: 10.4103/pm.pm_604_18 · 2019
Objective: The objective was to observe the effect of Juglone on the protein expression of caspase‑3, 9 in the apoptosis of Human Breast Cancer Cells (MCF7) and apoptosis‑related protein, Bcl‑2‑associated X protein (Bax)…
- Article
Effects of Atractylodes macrocephala Rhizoma on Isoproterenol‑Induced Myocardial Hypertrophy in Mice
Ke‑Zhao Wei, Xiao‑Hua Cui, Jia‑Hua Feng, Ping‑An Yao, Jian‑Ping Gao
pp. 579–585 · DOI: 10.4103/pm.pm_617_18 · 2019
Objective: The purpose of this study was to assess the effects of AMR on attenuating myocardial hypertrophy induced by isoproterenol (ISO) in mice. Materials and Methods: Mice were randomly divided into normal control gr…
- Article
Abd El‑Salam I. Mohammed, Arafa Musa, Marwa S. Abu‑Bakr, Hatem S. Abbass
pp. 586–591 · DOI: 10.4103/pm.pm_67_19 · 2019
Objective: The objective of the study is to investigate the anti‑eczematic activity, acute toxicity, and molecular modeling of A. microcarpus seeds. Materials and Methods: Nuclear magnetic resonance, ultraviolet, and mas…
- Article
Muneera S.M. Al-Saleem, Lamya H. Al-Wahaibi, Wael M. Abdel-Mageed, Yaser G. Gouda, Hanaa M. Sayed
pp. 592–599 · DOI: 10.4103/pm.pm_165_19 · 2019
Objective: We have studied the antioxidant chemical components from A. maurorum to determine their in vitro antiproliferative and hepatoprotective activities. Materials and Methods: The alcoholic extract of A. maurorum r…
- Article
Hong Li, Yuefeng Zhang, Hsiao‑Huei Chen, En Huang, Hailin Zhuang, Dan Li, Feng Ni
pp. 600–606 · DOI: 10.4103/pm.pm_22_19 · 2019
Objective: This study aimed to detect whether RA could inhibit the proliferation and migration of BCSCs through hedgehog (Hh) signaling while promoting apoptosis via Bcl‑2/ Bax. Materials and Methods: BCSCs from the huma…
- Article
Liqun Chen, Zhaoqun Jiao, Yufei Chen, Pingtian Yu, Yang Zheng, Yaya Yang, Yuping Shen, Huan Yang
pp. 607–612 · DOI: 10.4103/pm.pm_640_18 · 2019
Objective: In this study, we aimed to develop a species‑specific polymerase chain reaction (PCR) approach to detect deoxyribonucleic acid (DNA) fragments of ACC and TCC for rapid authentication purpose. Materials and Met…
- Article
Sheri‑Ann Tan, Shi Yun Lim, Chieu Shie Law, Chen Son Yue, Tze Ven Poh, Wan Zuhainis Saad, Saila Ismail, Khatijah Mohamad Yusoff, Chui Fung Loke
pp. 613–620 · DOI: 10.4103/pm.pm_84_19 · 2019
Objective: The present study aimed to determine the antioxidative and photocytotoxic effects of CME and SME toward liver cancer cells. Materials and Methods: Cell‑based (2′,7′‑dichlorodihydrofluorescein diacetate) and ch…
- Article
Lu Liu, Xiang Ding, Yiling Hou
pp. 621–630 · DOI: 10.4103/pm.pm_673_18 · 2019
Background: Polysaccharide has played the part of great role in pharmacology and physiology. Materials and Methods: In this study, the polysaccharides (CIS‑A) from Catathelasma imperiale (Fr.) Sing, were isolated and pur…
- Article
José Angel Santiago‑Cruz, Jesús Arrieta, Jazmín García‑Machorro, Daniel Arrieta‑Baez, María Elena Sánchez-Mendoza
pp. 631–637 · DOI: 10.4103/pm.pm_106_19 · 2019
Objective: The aim of the present study was to carry out a bioassay‑guided fractionation of Rauvolfia tetraphylla leaves to evaluate the activity on cervical cancer (HeLa) and normal cells. Materials and Methods: Of hexa…
- Article
Junjie Li, Yong Zhang, Linshan Jiao, Opeyemi Joshua Olatunji, Bing He
pp. 638–644 · DOI: 10.4103/pm.pm_164_19 · 2019
Background: The protective effects of the crude polysaccharide extract Polysaccharide Lycium chinense (PLC) from the leaves of Lycium chinense (Chinese wolfberry) were evaluated in streptozotocin (STZ)‑induced diabetic r…
- Article
Mingyu Cui, Conghui Li, Xiaoyue Kong, Kai Zhang, Yuanyuan Liu, Qimeng Hu, Yingli Ma, Yanfeng Li, Tingting Chen
pp. 645–651 · DOI: 10.4103/pm.pm_584_18 · 2019
Background: Galium verum L., a traditional Chinese medicine, has been widely used in the folk in China. Preparations of G. verum L. were used to treat thromboembolic disease in clinic for many years and often combined wi…
- Article
Zeng‑Kun Qian, Fan Cui, Yun‑Xi Ling, Wen‑Juan Zhu, Xiao‑Qin Li, Zheng Mao, Min‑Ting Li
pp. 652–658 · DOI: 10.4103/pm.pm_441_18 · 2019
Background: Alismatis rhizome (AR) is a popular traditional Chinese medicine, used for hyperlipidemia and diabetes in China for centuries; Alisma polysaccharides (AP) are the bioactive components in AR. This study invest…
- Article
Alaa El‑Din E. Abdel‑Hamid, Riham Salah El Dine, Jandirk Sendker, Soheir M. El Zalabani, Meselhy R. Meselhy, Elena Jimenez‑Negro, Ashraf B. Abdel‑Naim
pp. 659–670 · DOI: 10.4103/pm.pm_547_18 · 2019
Background: To assess the liver antifibrotic action of ethanolic extract of aerial parts of Solanum villosum Mill subsp. miniatum (Bernh. ex Willd.) (SVE) and correlate this activity with its high performance liquid chro…
- Article
Hossam Mohamed Abdallah, Gamal A. Mohamed, Sabrin R. M. Ibrahim, Hani Z. Asfour, Maan T. Khayat
pp. 671–674 · DOI: 10.4103/pm.pm_668_18 · 2019
Objective: In this work, the chemical investigation of Pulicaria undulata aerial parts was performed. In addition, the cytotoxic activity of the isolated metabolites was estimated toward various cell lines. Materials and…