Pharmacognosy Magazine · Archive
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In this issue
1–20 of 23Original Article
- Article
Marilyn Jane Yong, Ahmad Zaidi Tani, Falah Abass Mohamed Salih, Rahmawati Pare, Rina Norgainathai, Siat Yee Fong
pp. 689–694 · DOI: 10.4103/pm.pm_121_20 · 2021
Objectives: The study aimed to assess the anticancer efficacy and associated mechanisms of the crude aqueous extract of C. nutans leaves (cCN) in MDA‑MB‑231 triple‑negative human breast cancer cells. Materials and Method…
- Article
Yeong‑Geun Lee, Rong Bo Wang, Hyoung‑Geun Kim, Dae‑Young Lee, Yeon‑Ju Kim, Nam‑In Baek
pp. 695–699 · DOI: 10.4103/pm.pm_208_20 · 2021
Objectives: We reviewed for the effects of cytotoxic lignans against various human cancer cells. Materials and Methods: Solvent extraction of fruits in aqueous methanol and fractionation of the extract into H2O, n‑BuOH, …
- Article
Kukhwa Kim, Daniel Lee, Yoonhyoung Kang, Seonkyung Jang, Seung‑Jeong Yang, Hyungwoo Kim
pp. 700–705 · DOI: 10.4103/pm.pm_245_20 · 2021
Objectives: We investigate the anti‑inflammatory effects of an ethanol extract of the seeds of T. orientalis (EETO) on a dinitrofluorobenzene‑induced mouse model of contact dermatitis (CD). Materials and Methods: We inve…
- Article
Hasnah Bahari, Azrina Zainal Abidin, Santhra Segaran Balan, Kokila Vani Perumal, Nurain Syahirah Rosli, Amalia Hazirah Ahamad Lotafi, Sharmmila Danabala, Malarmugila Manimaran, Nurul Husna Shafie, Maizaton Atmadini Abdullah, Azmiza Syawani Jasni
pp. 706–712 · DOI: 10.4103/pm.pm_142_20 · 2021
Objectives: This study was aim to investigate the effect of E. tapos supplementation in obese rat prior pregnancy on the female offspring’s body weight, liver and kidney profile, and histological changes of heart, liver,…
- Article
Himanshu Makwana, Devang Pandya
pp. 713–721 · DOI: 10.4103/pm.pm_264_20 · 2021
Background: Loss of expertise in Sanskrit language and medicinal plant identification as per ayurvedic texts has resulted in the creation of “Controversial Drugs,” i.e., plants with different botanical identities being u…
- Article
Singamala Hari Prasad, Ganjikunta Venkata Subbaiah, Sahukari Ravi, Boreddy Venu Gopal Reddy, Bhasha Shanmugam
pp. 722–729 · DOI: 10.4103/pm.pm_272_20 · 2021
Objective: In this study we investigated the quantifying and profiling of phenols in Acalypha indica polyphenol-rich fraction (PLF) and their therapeutic potential on hepatic tissue damage in streptozotocin (STZ) induced…
- Article
Neeraj Kumar Fuloria, Shivkanya Fuloria, Vijay Kumar Sharma, Mohammed Ali, Amit Singh, Pradeep Kumar Sharma
pp. 730–732 · DOI: 10.4103/pm.pm_250_20 · 2021
Objectives: The present investigation was intended to explore the CAFME for the presence of any new phytoisolate. Materials and Methods: The study involved the preparation of CAFME, followed by critical isolation through…
- Article
Liang Song, Yang Xu, Yongli Xuan, Di Zheng, Quan Zhang, Wenhua Li
pp. 733–737 · DOI: 10.4103/pm.pm_81_20 · 2021
Objectives: In this study, we established a model of contrast‑induced acute kidney injury with iohexol. This model was used to investigate whether astaxanthin (AST) attenuates oxidative stress and apoptosis by activating…
- Article
Yijun Fan, Ze Chun, Gang Wang, Shangrao Pu, Yuanzhi Pan, Jie Ma, Rongsu Miao, Aoxue Luo
pp. 738–744 · DOI: 10.4103/pm.pm_109_20 · 2021
Objectives: In order to screen a polysaccharide with antioxidant activity from Pholiota nameko. Methods and Materials: A water-soluble acidic P. nameko polysaccharide (PNP) was found from extraction with alkaline water. …
- Article
Guijae Yoo, Taek Hwan Lee, Jae Hyuk Lee, Kyo Bin Kang, Heejung Yang, Yong Kon Park, Sun Yeou Kim, Seung Hyun Kim
pp. 745–749 · DOI: 10.4103/pm.pm_344_20 · 2021
Objective: Simultaneous determination of two diterpenoids; continentalic acid (CA) and kaurenoic acid, in the water extract of A. continentalis using the high‑performance liquid chromatography (HPLC) was established for …
- Article
Cuesta Cuesta, Mario Riera‑Romo, Olga Echemendia, Lívia Macedo Dutra, Jackson Roberto Guedes Da Silva Almeida, Dayana Pérez‑martínez, Laurent Picot, Idania Rodeiro Guerra
pp. 750–756 · DOI: 10.4103/pm.pm_24_20 · 2021
Background: Seagrasses are an important component of Nearshore marine ecosystems and a rich source of secondary metabolites with important pharmacological properties. Materials and Methods: In this work, crude hydroethan…
- Article
Bibu John Kariyil, P. T. A. Usha
pp. 757–763 · DOI: 10.4103/pm.pm_118_20 · 2021
Objectives: The present study was undertaken to evaluate the acute oral toxicity of methanolic extract of seeds of Annona muricata (MAM) and chloroform fraction of MAM and to derive the lethal dose 50 (LD50) of chlorofor…
- Article
P. K. Lakshmi, Shweta Kumar, Neha Dobriyal, Chandan Sahi, Rajesh Singh Pawar
pp. 764–773 · DOI: 10.4103/pm.pm_366_20 · 2021
Background: Tinospora tuberculata Bumee is a climbing vine distributed throughout the South Asian countries and it is known to be a hypoglycaemic agent. However, its role in cytoprotection and cellular oxidation is uncle…
- Article
Walied M. Alarif, Mohamed A. Ghandourah, Ahmed Abdel‑Lateff, Nahed O. Bawakid, Ahmed Abdullah Alotaibi, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi
pp. 774–779 · DOI: 10.4103/pm.pm_300_20 · 2021
Objective: Xenia is an octocoral genus of family Xeniidae. It contains 98 species and is rich of xenican‑type diterpenoids. These compounds play an important role in the biological activity of Xenia. Different bioactivit…
- Article
Lorina Ineta Badger-Emeka, Promise Madu Emeka, Saif Aldossari, Hany Ezzat Khalil
pp. 780–788 · DOI: 10.4103/pm.pm_199_20 · 2021
Objectives: The antimicrobial effects of Terfezia claveryi and Terfezia boudieri (T. boudieri) against bacteria isolates associated with eye infections and their molecular mechanism were investigated. Materials and Metho…
- Article
Guoxi Gao, Chao Zhang
pp. 789–796 · DOI: 10.4103/pm.pm_538_19 · 2021
Background: Inflammation plays an important role in the progression of arthritis. The imbalance between pro‑inflammatory and anti‑inflammatory mediators regulates the induction and progression of arthritis. Nuclear facto…
- Article
Chao Ning, Shaoqi Ning, Heng Luo, Lei Yan
pp. 803–811 · DOI: 10.4103/pm.pm_106_20 · 2021
Objective: The present study was undertaken to evaluate their possible mechanism of action against adjuvant‑induced arthritis (AIA), i.e., Freund’s complete adjuvant (FCA)‑induced arthritis, in experimental rats. Materia…
- Article
Liu‑Qiang Zhang, Hai‑Bing Xue, Wei‑Liang Zhu, Yi‑Ming Li, Kai‑Xian Chen
pp. 812–816 · DOI: 10.4103/pm.pm_91_20 · 2021
Objectives: This communication report presents the results of chemical investigation and antioxidant capacity of the fruits of C. ovata. Materials and Methods: The polar fraction from the fruits of C. ovata was isolated …
- Article
Qiaoling Yang1+, Mili Shi1+, Guangming Liu, Fang Peng, Xiaobo Liu, Meixian Guo
pp. 817–829 · DOI: 10.4103/pm.pm_499_19 · 2021
Objective: The objective was to study the synergistic and attenuating effects of CII‑3 combined with cisplatin. Materials and Methods: A Lewis tumor‑bearing mouse model was established. After 15 days of continuous admini…
- Article
Hina Kausar, Lubna Abidin, Mohd. Mujeeb, Mohd. Aqil, Ozair Alam
pp. 830–835 · DOI: 10.4103/pm.pm_295_20 · 2021
Objectives: The study objective was to analyze the optimization of extraction parameters of khellin from A. majus L. by response surface methodology (RSM). Materials and Methods: Box–Behnken Design (BBD) of RSM was used …