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In this issue
1–20 of 29Original Research Article
- Article
Jian-hui Zhang, Li-jun Xie, Han-lu Wang, Hui Chen, Xiao-rong Meng, Xing Lin, Xin-fu Lin, Li-sheng Liao, Ting Chen, Jie-Wei Luo, Lu-yu Hong, Xin Chen
pp. 7–15 · DOI: 10.1177/09731296231169588 · 2024
Background: Ferroptosis is a novel type of regulated cell death and targeting ferroptosis may be a potential treatment strategy for lung cancer. Ziyuglycoside II (ZYG II) has a significant inhibitory effect on the growth…
- Article
Supriya Sudhakar Bhalerao, Asavari Anirudha Joshi, Suresh Khadke, Arulmozhi Sathiyanarayan
pp. 30–42 · DOI: 10.1177/09731296231198316 · 2024
Background: The prevalence of obesity is rising worldwide. Due to the side effects associated with modern drugs, there is a need for an alternative treatment for obesity management. Triphala (TP), a polyherbal formulatio…
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the ACOX, mTOR/ULK1 Pathways Ying-Xiao Wang, Xin-Ge Ke, Chen Wang, Kang-Bo Peng, He-Zhen Wu, Yan-Fang Yang
pp. 43–56 · DOI: 10.1177/09731296231197299 · 2024
Background: Non-alcoholic fatty liver disease (NAFLD) is severely affecting the quality of people’s life. Rhapontigenin (RA) is a stilbene compound isolated from Rhubarb L., which has been reported to have an effect on c…
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Sapna Salar, Pankaj Sharma, Gaurav Gaurav
pp. 57–71 · DOI: 10.1177/09731296231189619 · 2024
Background: Medicinal plants standardization is more concerning for its regulatory aspects based on safety, quality, and efficacy. Nyctanthes arbor-tristris is an Indian-origin medicinal plant that is used for numerous a…
- Article
Yongjie Lu, Lushi Cheng, Lu Ren, Dongqiu Chen, Shumin Guan, Siyang Zhu, Xian Xu, Bing Zhang, Minghui Tang, Chijian Zhang, Yong Ai, Lanyue Zhang, Tinggang He
pp. 72–80 · DOI: 10.1177/09731296231198931 · 2024
Background: Glabridin is one of the main components of the isoflavonoids in Glycyrrhiza glabra and possesses antiinflammatory, anti-bacterial, and anti-cancer effects. Objectives: Herein, the therapeutic effects and mech…
- Article
Gang Wang
pp. 81–88 · DOI: 10.1177/09731296231190686 · 2024
Background: Modern strategies to alleviate the harmful effects of organophosphate pesticide diazinon (DN) abnormalities were focused mainly on using natural compounds or their derivatives. DN is an organophosphate compou…
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Jia-chen Shi, Ping Wu, Yong-mei Li, Xiao-rui Li
pp. 89–100 · DOI: 10.1177/09731296231190691 · 2024
Objectives: Psoriasis vulgaris is an immune-mediated inflammatory skin disease that is associated with depression. In this study, we investigated the effect of Xiegan–Liangxue–Jiedu (XGLXJD) decoction, a traditional Chin…
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Fevziye Deniz Güler, Nurullah Ozdemir
pp. 101–106 · DOI: 10.1177/09731296231201210 · 2024
Background: There are many active substances in the composition of the Hypericum perforatum L. plant that have different and complex structures and show different pharmacological effects. It was accepted as a medicinal p…
- Article
Qianyu He, Hu Hao, Keke Zhao
pp. 107–115 · DOI: 10.1177/09731296231203454 · 2024
Objectives: Rutin protects and stabilizes hepatocytes and is used to treat hepatitis, liver cirrhosis, and other diseases. However, there is little evidence to suggest that Rutin is associated with CCl4-induced hepatotox…
- Article
Hongling Zhao, Na Li, Xiaoyan Cui, Yongzhou Yu, Zi Liu, Jianhui Chen, Yuxuan Tian, Chunying Zhao, Hui Xiong
pp. 116–126 · DOI: 10.1177/09731296231204152 · 2024
Background: Sanqi Xueshangning Capsules (SXC) is a famous Chinese patent medicine with a good curative effect on various gynecological pain diseases in China. However, its chemical composition and potential active ingred…
- Article
Jun-Hua Meng, Ping Ni, Yu-Ling Cao, Yu Zhang, Xiong Wang, Hong Zhang, Yong-Gang Chen
pp. 127–136 · DOI: 10.1177/09731296231189329 · 2024
Objectives: Prolactinoma is a common intracranial tumor with a high incidence and serious harm to human health. At present, there is only one therapeutic drug in China, bromocriptine, and the Chinese herb Prunella vulgar…
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Nouha Bouali, Hafedh Hajlaoui, Soumaya Arraouadi, Mohd Saeed, Munazzah Tasleem, Snoussi Mejdi, Adel Kadri
pp. 137–145 · DOI: 10.1177/09731296231202104 · 2024
Background: Phytopathogenic fungi remain the main infectious agents in plants, causing severe damage to the environment and human health. Thus, to reduce the usage of synthetically derived fungicides and perform agricult…
- Article
Sivasakthi Paramasivam, Senthamil Selvan Perumal
pp. 146–158 · DOI: 10.1177/09731296231196189 · 2024
Background: Osteoporosis is a chronic metabolic bone disease caused due to the dysregulation in the functioning of osteoblast and osteoclast cells leading to increased bone resorption predominantly in postmenopausal wome…
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Molecular Approach Jinwen Li
pp. 159–178 · DOI: 10.1177/09731296231203809 · 2024
Objectives: This study investigated the effects of BP and doxorubicin (DOX) on 4T1 tumor cells in a mouse model. Materials and Methods: After inducing breast tumors, 70 4T1-tumor-bearing BALB/c mice were divided into sev…
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Nidhi Sharma, Prerna Raina, Ghazalla Mulla, Anand Shindikar, Prajakta Patil, Supriya Bhalerao, Ruchika Kaul-Ghanekar
pp. 179–188 · DOI: 10.1177/09731296231204132 · 2024
Background: In India, cancer of the cervix is the second most common cancer in women. Nowadays, various traditional herbal formulations can be used as adjuncts during conventional cancer therapies due to their anticancer…
- Article
Xiaohui Chen, Panpan Liu, Yanni Mao, Guiqin Wang
pp. 189–205 · DOI: 10.1177/09731296231203458 · 2024
Matrine possesses a broad spectrum of pharmacological activities as one of the primary components of Chinese herbal medicine Sophora flavescens extract, along with fewer side effects and low toxicity. Matrine possesses a…
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Farah Syahibah Mohd Hariri, Asmah Hamid, Nor Fadilah Rajab
pp. 206–217 · DOI: 10.1177/09731296231207226 · 2024
Background: Zingiber zerumbet (L.) Smith (lempoyang) has a traditional application in the treatment of indigestion, worm infestation, loss of appetite, and postpartum conditions. Objectives: Extracts of Z. zerumbet (meth…
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Imen Bédoui, Hmed Ben Nasr, Kamilia Ksouda, Wajdi Ayadi, Nour Louati, Mohamed Chamkha, Sirine Choura, Jalel Gargouri, Serria Hammami, Hanen Affes, Walid S. Hamadou, Nourhene Zammel, Subuhi Sherwani, Khaled Zeghal, Riadh Badraoui
pp. 218–229 · DOI: 10.1177/09731296231207231 · 2024
Background: Finding new effective substances to develop drugs against cancer or to prevent it remains a big challenge facing scientists and clinicians. Objectives: In such an issue, we tested the anti-tumoral effect of S…
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Zi-Yao Li, Qin Yang, Xiao-Ge Cheng, Yan-Li Zhou, Xiang-Ling Piao, Li Qiu, Bo-Jun Zhou, Song-Tao Wu
pp. 230–244 · DOI: 10.1177/09731296231206300 · 2024
Background and Objectives: 4-Methylumbelliferone (4-MU) is a coumarin compound that can be extracted from the medicinal plant with anti-cancer properties, Smilax china L. In recent years, studies have revealed its potent…
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Antibiotic-treated Rats Di Cao, Zhengjiao Wang, Xiuting Shen, Xiaojun Song, Zhongxiang Zhao
pp. 245–256 · DOI: 10.1177/09731296231198608 · 2024
Background: Ilexsaponin A1 (IA1) is a bioactive triterpene saponin derived from natural medicinal plants. IA1 exhibits antiinflammatory and proangiogenic activities and improves intestinal barrier function. It has been r…