Pharmacognosy Magazine · Archive
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In this issue
1–20 of 28Original Article
- Article
Sharmistha Ganguly, Jyoti Kumar, Tapan Seal
pp. 209–215 · DOI: 10.4103/pm.pm_550_20 · 2021
Objectives: The present study focused on evaluation of the total phenolic content, total flavonoid content, and reducing and antioxidizing activities from methanolic extract of different plant parts, namely leaves, stem,…
- Article
Baolian Ma, Shilin Yang, Junmao Li, Zhiqi Wen, Hui Ouyang, Wugang Zhang, Yulin Feng, Mingzhen He
pp. 216–222 · DOI: 10.4103/pm.pm_336_20 · 2021
Objective: Curcumol extracted from the traditional Chinese medicine (TCM) E‑Zhu (Curcumae Rhizoma), is one of the chief bioactive ingredients of Curcuma oil (a marketed drug in China). Materials and Methods: To classify …
- Article
Huaying Zhou, Zhong Li, Dehan Luo, Hamid Gholamhosseini, Bin Han, Hexian Wang
pp. 223–230 · DOI: 10.4103/pm.pm_187_20 · 2021
Background: Amomi fructus (AF) (a dried fruit of Amomum villosum Lour.) has been used in the treatment of digestive diseases such as abdominal pain and dysentery and in the prevention of abortion. The active ingredient o…
- Article
Huixia Ma, Yafei Zhu, Zhengjun Zhang, Xinhui Zhang, Qipeng Zhao
pp. 231–235 · DOI: 10.4103/pm.pm_360_20 · 2021
Background: Costunolide (Co) has anti‑tumor, anti‑inflammation, and anti‑ulcer effects, it has the budding effect of anti‑apoptosis. This study was intended to explicate its inhibitory effect on caspase in a mice brain s…
- Article
Rameshkumar Santhanam, Gothai Sivapragasam, Thiruventhan Karunakaran, Katyakyini Muniandy, Senthilkumar Palani Kandasamy, Arulselvan Palanisamy
pp. 236–243 · DOI: 10.4103/pm.pm_433_20 · 2021
Objectives: The aim is to determine the anti‑inflammatory mechanism of various solvent fractions of F. deltoidea methanol extract against Lipopolysaccharide (LPS)‑induced nuclear factor‑kappa B (NF‑κB) inflammatory pathw…
- Article
Hua-Long Lin, Pei-Rui Chen, Chun-Chun Mao, Wei-E Zheng, Jia-Qi Wang
pp. 244–249 · DOI: 10.4103/pm.pm_53_20 · 2021
Objectives: In this current investigation, we observed the anticancer and proapoptotic potentials of ferruginol (FGL) in human colon cancer (HCT‑116) cells. Materials and Methods: We recognized that the potentials of FGL…
- Article
Hong Mu, Ying Pang, Lili Liu, Fengshan Li, Jianqi Wang
pp. 250–255 · DOI: 10.4103/pm.pm_242_20 · 2021
Background: Osteoporosis tends to be the major consequence of fractures in women above the age of 50 years and men are prone above the age of 65 years. The structure of bone is severely deteriorated by the reduction in b…
- Article
Li Li, Jingwen Gong, Hailong Li, Mingyan Zhou, Yinfeng Tan, Junqing Zhang
pp. 256–262 · DOI: 10.4103/pm.pm_65_20 · 2021
Background: Topical effects are essential mechanisms of nonsteroidal anti‑inflammatory drugs (NSAIDs)‑induced gastric damage. Our previous study showed that the extract of Alpinia officinarum (AOE) may have some protecti…
- Article
Arshi Naqvi, Reem A. K. Al‑Harbi, Samah Ali, Richa Malasoni, Swati Gupta, Anil Kumar Dwivedi
pp. 263–267 · DOI: 10.4103/pm.pm_317_20 · 2021
Objectives: In the present study, novel marker compounds (A and B) have been successfully isolated from NCCL and their various in silico traits and interactions were studied. Materials and Methods: Marker compounds A and…
- Article
Debo Yun, Yujiao Yang, Bin Shang, Heng Dong, Bo Luo, Tahani Awad Alahmadi, Qing Luo
pp. 268–274 · DOI: 10.4103/pm.pm_261_20 · 2021
Objective: In this study, we examined the therapeutic role of kirenol against I/R‑induced neuronal damage by inhibiting inflammation in Sprague‑Dawley (SD) rats. Materials and Methods: I/R was induced in SD rats and subs…
- Article
Xinxin Liang, Jian Shen, Xueming Duan, Rongbing Zhou, Peng Liu, Xiaoming Chi
pp. 275–281 · DOI: 10.4103/pm.pm_41_20 · 2021
Objectives: In this study, the chemoprotective effect of resveratrol and its of mechanism of action against the Lipopolysaccharide (LPS)-induced lung inflammation was investigated. Materials and Methods: In this in vitro…
- Article
Yaoyao Wang, Yujiang Chen, Mao Yang, Chunlin Chen
pp. 282–287 · DOI: 10.4103/pm.pm_561_19 · 2021
Aim: The aim of this study was to evaluate the effects of ginsenoside Rb1 on the level of brain natriuretic peptide (BNP) in serum and the expression of caspase‑3 protein in the cardiomyocytes of CHF rats. Subjects and M…
- Article
Nootchanat Mairuae, Poonlarp Cheepsunthorn, Benjaporn Buranrat, Supataechasit Yannasithinon
pp. 288–292 · DOI: 10.4103/pm.pm_393_20 · 2021
Objectives: The present study aimed to investigate the anti‑inflammatory and antioxidant role of OIS extract in a neuroinflammatory model of lipopolysaccharide (LPS)‑stimulated microglia cells. Materials and Methods: BV2…
- Article
Lihua Chen, Yingying Shan, Chunmei Wang, He Li, Jianguang Chen, Jinghui Sun
pp. 293–301 · DOI: 10.4103/pm.pm_255_20 · 2021
Aim: In this study, we aimed to evaluate the hepatoprotective mechanism of SCP in immunological liver injury. Subjects and Methods: In this study, we performed rapid‑resolution liquid chromatography coupled with quadrupl…
- Article
Gerson S. Lima, Gerzia C. Machado, Maria A. M. Maciel, Aurea Echevarria
pp. 302–306 · DOI: 10.4103/pm.pm_345_20 · 2021
Objectives: The objective of the study is to evaluate the stem bark hydroalcoholic extract (CC‑EHA) of C. cajucara and their clerodane‑type diterpene fractions (F1‑7, F25‑27, and F28) on promastigotes and axenic amastigo…
- Article
Song Ee Han, Min Ji Kwon, Jeong Nam Kim, Eun Yeong Lim, Yun Tai Kim, Byung Joo Kim
pp. 307–314 · DOI: 10.4103/pm.pm_127_20 · 2021
Objectives: The mechanisms of cell death induction by CF were investigated in AGS human gastric adenocarcinoma cells. Materials and Methods: Cell viability assay, cell cycle analysis, caspase activity assay, western blot…
- Article
Yun Sun, Hui Yao, Xin Zhang, Xiao-Xuan Yuan, Han-Lin Xu
pp. 315–320 · DOI: 10.4103/pm.pm_275_20 · 2021
Objective: In this study, our primary goal was to understand the mechanism of action of Elaeagnus angustifolia L. leaves (EALs) in protecting Rat Schwann cells (RSC-96) against H2O2-induced oxidative stress. Materials an…
- Article
Yue Fan, Si-Lin Huang, Hong Li, Yu-Lin Cui, Dong-Yan Li
pp. 321–326 · DOI: 10.4103/pm.pm_312_20 · 2021
Objectives: In this study, we aimed to determine whether RES attenuates inflammation by regulating macrophage polarization through inhibition of toll‑like receptor 4 (TLR4)/ MyD88 signaling. Materials and Methods: We mea…
- Article
Meng Wang, Shuguang Yan, Jingyi Kong, Yongxue Zhou, Pei Xie
pp. 327–333 · DOI: 10.4103/pm.pm_85_20 · 2021
Background: The pathogenesis of depression is related to the NOD‑like receptor protein 3 (NLRP3) inflammasome activation and low level of mitophagy. In traditional Chinese medicine, Paeonia lactiflora Pall is a common he…
- Article
Na Song, Junyi Ma, Xuemei Zhang, Danni Qu, Ling Hui, Chunyan Sang, Haining Li
pp. 334–341 · DOI: 10.4103/pm.pm_251_20 · 2021
Objectives: The objective of this study was to examine the antitumor effect and primary mechanisms of LH on cell proliferation, cell cycle, and apoptosis in HepG2 cells. Materials and Methods: The cell viability and prol…