Volume 16, Issue 3

Mohammad Daud Ali, Ebrahim Ahmed Jaber Al Hatef, Hassin Shabbab Hassin Alamri

pp. 374–384 · DOI: 10.5530/jyp.2024.16.49 · 2024

Qualitative research is a method of collecting data that does not involve numbers. It is used to understand human behavior, attitudes, beliefs and personality traits. It is different from quantitative research as it does…

Pooja Rathore, Vivek Mishra, Navneet Bansal, Ananya Sharma, Arti Saini, Inderjeet Verma

pp. 385–390 · DOI: 10.5530/jyp.2024.16.50 · 2024

Treponema pallidum(T. pallidum) transmits syphilis through sexual contact or perinatal transmission. T. pallidumis widely known for being invasive and immune-evasive; its clinical symptoms are commonly mistaken for those…

Mamta Kumari, Dipti Gohil, Piyushkumar Sadhu, Chitrali Talele, Niyati Shah, Nirmal Shah

pp. 391–399 · DOI: 10.5530/jyp.2024.16.51 · 2024

Rheumatoid Arthritis (RA) is a chronic autoimmune condition causing joint inflammation and damage. Despite treatment progress, effective topical therapies pose challenges. Animal models, like Collagen-Induced Arthritis (…

Sruthi Somadasan, Gopinath Subramaniyan, Meriton Stanly Athisayaraj, Satheesh Kumar Sukumaran

pp. 400–409 · DOI: 10.5530/jyp.2024.16.52 · 2024

Design and optimization are pivotal in a pharmaceutical company's formulation and manufacturing process. Various approaches and methodologies are employed in formulation design. A quantitative adjustment to a component, …

Lavani Firdos, Chinthaginjala Haranath, Singareddy Yasaswini, Rompicharla Narasimha Sai, Turubilli Satish

pp. 410–415 · DOI: 10.5530/jyp.2024.16.53 · 2024

A potential development in medication administration, transferosomes are lipid-based vesicles that have been designed with edge activators, especially for transdermal and transmucosal uses. Transferosomes, which are most…

Shobhana N, Prakash Goudanavar, Mallamma T, Butchi Raju Akondi

pp. 416–424 · DOI: 10.5530/jyp.2024.16.54 · 2024

Magnetic Nanoparticles (MNPs) are now being utilized more frequently in experimental research on cancer treatments, which has become one of the most difficult problems in medical science. The fundamental objective of thi…

Bipin Shaji, Juno Jerold Joel, Raghava Sharma

pp. 425–430 · DOI: 10.5530/jyp.2024.16.55 · 2024

Vitamin D has a crucial role in maintaining thyroid and immune function. In hypothyroidism, the gland is underactive and Vitamin D impacts this condition. Vitamin D regulates gene expression in thyroid hormone synthesis …

Saurav Raj, Megha Hegde, Sanatkumar Bharamu Nyamagoud, Shamita Shyam Sail, Chandrashekhar Patil, Kaushal Kumar, Nikhil Bohra

pp. 431–438 · DOI: 10.5530/jyp.2024.16.56 · 2024

The gut microbiome is being frequently acknowledged for its impact on intestinal and extra-intestinal conditions, notably cancer. Here, diet is the most extensively researched modulator of gut microbiota among various en…

Girish B S, Joel M. Johns, C. S Meghana, R. Srinivasan

pp. 439–446 · DOI: 10.5530/jyp.2024.16.57 · 2024

Cardiovascular Diseases (CVD) have claimed millions of lives, despite the efforts of medical professionals. There are several treatment methods for blocking a few neurohormonal cascades; however, it is debatable because …

Udigala Renukaprasad Rakshith, Salini Parameswaran Nair, Arjun Hunsur Ranganath, Praveen Halagali

pp. 447–455 · DOI: 10.5530/jyp.2024.16.58 · 2024

Drug interactions represent a significant challenge in modern medicine, as the concomitant use of multiple medications is prevalent in-patient care. Understanding the mechanisms behind drug interactions, accurately asses…

Neena Elsa Varghese, Vinitha Chandrasekaran, Krishnaveni Kandasamy, Kameswaran Ramalingam

pp. 456–460 · DOI: 10.5530/jyp.2024.16.59 · 2024

The global impact of Severe Acute Respiratory Syndrome Coronavirus-2 (SARSCOV2) is profound, with Coronavirus Disease 2019 (COVID-19) presenting a clinical spectrum that leads to multi-systemic failure, particularly affe…

Anjali S. Katore, Anita Wanjari, Utkarsha Kandalkar, Harlin Swer

pp. 461–468 · DOI: 10.5530/jyp.2024.16.60 · 2024

Background:Medicated oils and Clarified butter are often utilized in the Traditional System of Indian Medicine for internal and external use. To improve the durability and efficacy of therapeutic oil unique processing is…

Sanjay R. Ugare, Nayeem A. Khatib, Faizan A. Beerwalaa, Ashwini Ratnakar, Dhanashree Patil, Vishal S. Pati, Darasaguppe R. Harish

pp. 469–479 · DOI: 10.5530/jyp.2024.16.61 · 2024

Background:Non-Alcoholic Fatty Liver Disease (NAFLD) is most prevalent global health problem, develops due to accumulation lipids in the hepatocytes in the form of Triglycerides (TG) and Free Fatty Acids (FFA). Tradition…

Rama Manda, Narsimha Reddy Yellu

pp. 480–487 · DOI: 10.5530/jyp.2024.16.62 · 2024

Objectives:Alzheimer's disease is primarily caused by neurotoxic effects of amyloid beta Aβ(25-35) peptide accumulation and increased levels of Acetylcholinesterase Enzyme (AChE). Acetylcholinesterase inhibitors report f…

Kamlesh Machewar, Rajendra Kakde, Prafulla Sabale

pp. 488–497 · DOI: 10.5530/jyp.2024.16.63 · 2024

Background:The present study is designed to develop a novel dosage form i.e. microemulgel which will enhance the rate of absorption in the systemic circulation and ultimately enhance the pharmacological effect of the Men…

Nikita Shridhar Andhale, Rohit Jaysing Bhor, Mahesh Hari Kolhe, Tanishka Anil Pawar, Pornima Ramdas Tambe, Rupali Mahadev Ghule, Sarthak Anil Bhange, Bhakti Sharad Thete, Pruthviraj Vijay Kute, Pratik Vijay Malvade, Jyoti Ramkisan Bhagat, Poonam Prakash Waykar

pp. 498–505 · DOI: 10.5530/jyp.2024.16.64 · 2024

Background:Five-membered heterocycle with one neighbouring nitrogen atoms is present in the indole nucleus. Heterocyclic substances feature two adjacent benzene and pyrrole ring atoms. Indole are heterocyclic compounds w…

Kurubara Amaresh, Madiwalayya Shivakantayya Ganachari, Revanasiddappa Devarinti

pp. 506–519 · DOI: 10.5530/jyp.2024.16.65 · 2024

Background:Pharmaceutical sponsors have a significant responsibility in gathering and overseeing the storage of leftover human biological samples. Understanding the proper utilization and potential risks associated with …

Rithanya Sureshkumar, Nithyananth Muniswamy

pp. 520–534 · DOI: 10.5530/jyp.2024.16.66 · 2024

Background:Gemcitabine (GEM), a Biopharmaceutical Classification System (BCS) class-III drug, holds promise for non-small cell lung cancer treatment. Utilizing lipid-based nanoparticles for targeted delivery has proven e…

Koushik Yetukuri, Barakathulla Mohammad, Vimala Nookala, Nikitha Pentyala, Ujwala Kondaveeti, Shalini Palla, Vikas Madapati, Venkateswara Rao Vishnumolakala, Rama Rao Nadendla

pp. 535–546 · DOI: 10.5530/jyp.2024.16.67 · 2024

Background:In this study, neemoil's therapeutic potential against bacterial inflammations is explored through nanoemulsion technology. Despite its historical significance in traditional medicine, neemoil formulations fac…

Rincy Roy, Veintramuthu Sankar, Pranav Ragavendra

pp. 547–555 · DOI: 10.5530/jyp.2024.16.68 · 2024

Background:Nano-structure Lipid Carriers (NLCs) are small spheres extending in scale from 10 to 1000 nanometres comprised of biocompatible and biodegradable lipids. These spheres can encapsulate both hydrophilic and lipo…