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In this issue
21–40 of 43Original Research Article(continued)
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Asma M. Hajla, Afrah Al-Khuraiji, Doaa M. El-Nagar, Nawal M. Al-Malahi, Ibrahim O. Alanazi, Rewaida Abdel-Gaber
pp. 1390–1398 · DOI: 10.1177/09731296251313618 · 2025
Background: Breast cancer remains a significant global health burden despite advancements in treatment. While conventional therapies often induce adverse effects, there is growing interest in exploring natural alternativ…
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that curcumin can activate Nrf, China. E-mail: zhangzhiyuan2024@163.com Polydopamine Nanoparticles-coated Curcumin Upregulates the Expression of Nrf2 through the Keap1/ARE Signaling Pathway to Improve Liver Injury in Mice with Liver Cancer Qingqing Zhou, Zhiyuan Zhang
pp. 1399–1408 · DOI: 10.1177/09731296251313613 · 2025
Background: Liver cancer is a complex disease, and the upregulation of Nrf2, a key molecule in the Keap1/ARE signaling pathway, is expected to become a new method for liver cancer and prevention. Curcumin is a natural an…
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Yanhua Yu, Tian Hu, Guiwei Zhong
pp. 1409–1417 · DOI: 10.1177/09731296251313641 · 2025
Background: The abnormal expression of metastasis-associated gene 1 (MTA1) is related to the proliferation of tumor cells. Curcumin lipid nanoemulsion can effectively inhibit the growth of cervical cancer cells. Objectiv…
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Xinjun Chen, Zhuo Wu
pp. 1418–1426 · DOI: 10.1177/09731296251313612 · 2025
Background: Gentamicin (GM), a commonly used aminoglycoside anti-biotic, is effective against various bacterial infections. However, its clinical use is often limited due to its significant nephrotoxic side effects. Neph…
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Jiayuan Yang, Jiawei Tian, Erhao Zheng, Qi Li, Chen Chen, Zhimin Geng, Jigang Bai
pp. 1427–1437 · DOI: 10.1177/09731296251313627 · 2025
Background: Curcuma phaeocaulis (CP) is utilized as a Chinese herbal medicine to treat abdominal distension and other related ailments. Curcuma phaeocaulis extracts (CPE) are rich in active components and exhibit anti-tu…
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Saurabh Maru, Sateesh Belemkar
pp. 1438–1448 · DOI: 10.1177/09731296241311345 · 2025
Background: Disease prevention prevailed in the post-COVID world. The global trends are trailing toward prevention and immunity enhancement with alternative therapies and herbal drugs. Objectives: The current research wa…
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Fangqin Li, Xinying Luan, Yingying Yao, Xiaohua Cao
pp. 1449–1458 · DOI: 10.1177/09731296251318787 · 2025
Background: Lung cancer is a deadly type of cancer and is the primary cause of cancer-related deaths in both males and females worldwide. The number of lung cancer cases has risen worldwide due to a growing population of…
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Katsuya Yuui, Risa Kudo, Shogo Kasuda, Shigeru Ueshima
pp. 1459–1468 · DOI: 10.1177/09731296251313616 · 2025
Background: The potential of cyanidin 3-O-β-D-glucoside (C3G), known for its anti-obesity and anti-diabetic properties, in suppressing arteriosclerosis progression remains unexplored. Objectives: This study aimed to eluc…
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Naihong Xu, Dongrong Zhao
pp. 1469–1479 · DOI: 10.1177/09731296251348082 · 2025
Background: Anxiety and depression are among the most widespread mental health conditions worldwide, impacting millions and imposing a considerable burden on individuals and healthcare systems. Objectives: The present re…
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Li Li, Le Liu, Tingting Wang
pp. 1480–1486 · DOI: 10.1177/09731296241312483 · 2025
Background: Scar recovery in elderly burn patients is essential for wound healing and psychological well-being. Total glycosides from Centella asiatica have gained attention for their anti-inflammatory, antioxidant, and …
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Ashok Godavarthi, Seul A. Seo, Sang Hyun Park, Soo-Hyeon Heo, H.N. Shivaprasad
pp. 1487–1499 · DOI: 10.1177/09731296251317254 · 2025
Background: Age-related macular degeneration (AMD) is one of the major leading irreversible reasons for severe blindness in the aged population. Oxidative stress is said to be a leading cause of AMD and is very progressi…
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Jingwen Shao, Shaoyi Qu, Jingwang Jingwang, Dan Sun, Qing Hu, Zhongxiang Luo
pp. 1500–1509 · DOI: 10.1177/09731296251321905 · 2025
Background: Cerebral ischemic stroke, a devastating neurological condition, occurs when the blood supply to a specific region of the brain is interrupted, leading to a cascade of complex physiological and biochemical pro…
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Yuanzhi Li, Chaochi Yue, Yingyin Liao, Weiliang Du
pp. 1510–1518 · DOI: 10.1177/09731296251320700 · 2025
Background: In our previous research, we addressed the issues of poor stability and water solubility of scutellarin by developing scutellarin nanoparticles. Our findings indicated that these nanoparticles exhibited enhan…
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Guochen Sui, Zhuoran Zhang, Xuejun Tian, Yunping Miao, Min Cheng, Wei Pan, Gaoli Zheng, Xiaodi Ye
pp. 1519–1529 · DOI: 10.1177/09731296251324706 · 2025
Background: Cordyceps sinensis is a unique and precious Traditional Chinese Medicine. The fermented mycelia of C. sinensis are obtained from the medicinal strains isolated from C. sinensis by liquid-submerged fermentatio…
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Ahmad A. Alghamdi
pp. 1530–1536 · DOI: 10.1177/09731296251321565 · 2025
Background: Cynanchum radians (C. radians) is a small herb from the Asclepiadoid genera, found in both the Old and New Worlds. The plant has potential medicinal properties, but its effects on coagulation have yet to be f…
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Jiaxin Wang, Juan Liu, Yahui Wang, Kailibinuer Abulaiti, Weili Sun, Maihesumu Aikemu, Muhebuli Abulizi
pp. 1537–1548 · DOI: 10.1177/09731296251321906 · 2025
Background: Vitiligo is a skin condition characterized by depigmentation and has proven difficult to treat. Traditional Chinese Medicine (TCM) offers potential therapeutic alternatives. Compound Baqian Danshen Liniment (…
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Jie Zhou, Weilong Li, Xina Yu, Ye Wu, Pei Luo, Qingquan Kong, Zhifeng Zhang
pp. 1549–1561 · DOI: 10.1177/09731296251322836 · 2025
Background: Animal-derived remedies are prominent in folk medicine worldwide, and discovering potent anti-inflammatory agents is attractive for rheumatoid arthritis (RA) treatment. Himalayan marmot oil (HMO), a tradition…
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Downregulating ACSL4 Meixiao Liu, Yuelin Sui, Yin Pang, Jianhui Liu, Haifeng Zhang
pp. 1574–1584 · DOI: 10.1177/09731296251322834 · 2025
Background: Diabetic nephropathy (DN) is a severe complication in patients with diabetes mellitus, which is mainly characterized by glomerular podocyte injury. Ferroptosis is crucial in the pathogenesis of DN. Moringa ol…
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Esam S. Al-Malki, Rewaida Abdel-Gaber, Najwa Almutairy, Nawal Al-Hoshani, Rasha Alonaizan, Andreas Meryk, Esam M. Al-Shaebi, Mohamed A. Dkhil, Saleh Al Quraishy
pp. 1585–1596 · DOI: 10.1177/09731296251313859 · 2025
Background: Coccidiosis is considered a protozoan disease affecting wild and domestic animal species which leads to economic losses. Regarding drug resistance, scientists are focused on alternative sources rather than co…
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Hua Jin, Ta Na, Yue-hui Liu, Qian-qian Ma, Ming-qi Liu, Ruo-shui Zhou, Liang Wei, Hong-quan Jin, Dong-wei Zhang
pp. 1597–1607 · DOI: 10.1177/09731296251324721 · 2025
Objectives: To study the antioxidant effects of the traditional Mongolian medicine Zha-Chong-Shi-San-Pill ethanol extract (EEZC) on cerebral stroke for future clinical use. Materials and Methods: Active components and me…