Volume 17, Issue 3

Phaik Har Yong, Ng Soon Kee, Meram Azzani, Deepa Anbazhagan, Zhi Xiang Ng

pp. 483–494 · DOI: 10.5530/jyp.20251697 · 2025

Diabetes and related complications are becoming the leading causes of death in the world. In Malaysia, there are around 3.4 million of people affected by diabetes. Long-term diabetes can lead to the development of variou…

Kumara Swamy Samanthula, Agaiah Goud Bairi, Daniel Kothapally

pp. 495–503 · DOI: 10.5530/jyp.20251309 · 2025

In recent decades, there has been a growing fascination with delivering therapeutic agents through transmucosal (buccal, sublingual, nasal, rectal, and vaginal) drug delivery systems. Drug delivery through oral transmuco…

Priyanka Kotla, Rashmi Nelligare Gopalkrishna

pp. 504–510 · DOI: 10.5530/jyp.20251790 · 2025

This review focuses on the advancements in liquid chromatographic techniques to do both qualitative and quantitative research on cyclosporine and gingerol, with particular emphasis on their incorporation into Novel Drug …

Debasis Patra, Kirtimaya Mishra, Asra Jabeen, Prasanna Parida, Abhilash Dash, Gowri Sankar Chintapalli, Diptimayee Jena

pp. 511–519 · DOI: 10.5530/jyp.20251687 · 2025

Sjögren's Syndrome (SS), a systemic autoimmune condition, that is characterised by the presence of dry eyes along with dry mouth. However, it is important to note that the effects of this disorder are not limited to thes…

Deepak Kumar Jha, Darshan Rajashekhar

pp. 520–531 · DOI: 10.5530/jyp.20250012 · 2025

There is growing evidence highlighting a significant risk of cardiovascular complications in patients recovering from COVID-19, particularly among those experiencing long COVID or persistent post-acute symptoms. Numerous…

Vimala Ananthy, Priyadharsini Raman Palanisamy, Umamaheswari Subramanian

pp. 532–536 · DOI: 10.5530/jyp.20250058 · 2025

The discovery of biased agonism as a pharmacological technique that enables specific receptor pathway activation through ligands transformed receptor pharmacology. The analysis evaluates the fundamental mechanisms and me…

Fazlina Mustaffa, Geethaa Sahgal, Varatharajan Rajavel, Yamunna Parasmawaran, Mohamed Asem Ameerdin, Jeevandran Sundarasekar, Baala Sharmma, Vimalah Devi

pp. 537–542 · DOI: 10.5530/jyp.20250105 · 2025

Background:On average, 20 tree barks are used for the production of animal bedding for Malaysian research universities that carry out animal testing yearly. Even though this figure looks small, sustainable environmental …

Josef Yakin, Faruk Alam

pp. 543–550 · DOI: 10.5530/jyp.20250071 · 2025

Background:Medicinal plants have historically played a crucial role in healthcare, serving as the basis for many modern drugs. Among these, Drymaria cordata(L.) Willd. ex Schult., a small herbaceous plant of the Caryophy…

Richa Yadav, Jaya Parkash Yadav

pp. 551–558 · DOI: 10.5530/jyp.20251475 · 2025

Background:Concerns regarding the detrimental consequences of oxidative stress on human health have grown recently on a global scale and herbal treatment approaches to treat oxidative stress-related illnesses in humans a…

Vaibhav Kumar Rathi, Mukesh Singh Sikarwar, Pushpendra Kumar Shukla

pp. 559–570 · DOI: 10.5530/jyp.20250180 · 2025

Objectives:This study explores microscopic features, physicochemical properties, preliminary phytochemical profile, antioxidant and antibacterial activity of Ludwigia palustris. Materials and Methods:Macroscopic and micr…

Raman Lakshmisundaram, Kalaivani Madhavaram Kuppusamy, Logeshwari Muruganandham, Krishna Priya Rajaram Baskaran, Dhanalakshmi Muniyandi, Mudiganti Ram Krishna Rao, Jayasutha Jayram

pp. 571–580 · DOI: 10.5530/jyp.20250031 · 2025

Background:The present study deals the biological property of a medicinal plant, Peristrophe bicalyculata. This is a common herb used for a number of ailments ethno-pharmacologically. In the present study, the antioxidan…

Shailesh Deshpande, Meha Gandhi, Vaishali Deshpande

pp. 581–591 · DOI: 10.5530/jyp.20250163 · 2025

Background:Meha Mudgara Rasa(MMR) is a classical Ayurvedic herbo-mineral formulation that is traditionally used in the management of diabetes. Despite its long-standing therapeutic use, scientific validation of its pharm…

Afrasim Moin, VRSS Prashanth Pedamallu, Sateesha Shivally Boregowda, Rajamma Abbur Jayaramu, Sathvik Kudkuli, Amr Selim Abu Lila

pp. 592–603 · DOI: 10.5530/jyp.20251479 · 2025

Background:An antifungal drug, fluconazole, was selected as a model drug in this study to comprehend the effect of temperature and moisture on polymorphic transformation. Materials and Methods:Three polymorphs of flucona…

Pritam Timothy Pradhan, Aradhana Panigrahi, Jasaswi Ray, Rabi Sankar Dash, Gurudutta Pattnaik, Abhisek Sahu, Bikash Ranjan Jena, Yashwant Giri

pp. 604–611 · DOI: 10.5530/jyp.20251665 · 2025

Background:Onychomycosisis is a fungal nail infection mainly caused by funguses like Trichophyton rubrum, Aspergillus, and various species of Candida that impact the nail. Symptoms can manifest as a color change of the n…

Koushik Yetukuri, Surya Pavan Kumar Gollapudi, Aditya Reddy Mukkala, Guna Shankar Mandala, Ameenul Ahad Shaik, Ayush Katyayan, Rama Rao Nadendla

pp. 612–619 · DOI: 10.5530/jyp.20250006 · 2025

Background:The formulation and optimization of an activated charcoal-based antibacterial soap were investigated to enhance cleansing efficacy and antimicrobial properties. The study was conducted at Chalapathi Institute …

Naser M.Y. Hasan

pp. 620–626 · DOI: 10.5530/jyp.20250153 · 2025

Background:The increasing interest in the field of Lipid Self-Emulsifying Technology (LSET) is due to the fact that 40% of new chemical entities exhibit poor oral bioavailability because of their low water solubility. Se…

Ajit Nahak, Aditya Narayana Padhi, Anjan Kumar Mahapatra, Asish Sahu, Kakinada Sonu Kumar, Amaresh Prusty

pp. 627–635 · DOI: 10.5530/jyp.20250088 · 2025

Background:Lipstick is a solid cosmetic designed to impart vibrant colour, hydration, and textural enhancement to the lips. With a growing consumer shift toward natural products. Interest in plant-based colorants and nat…

Sachin Balkrishna Somwanshi, Harsha Kailas Donde

pp. 636–645 · DOI: 10.5530/jyp.20250014 · 2025

Background:Itraconazole, a broad-spectrum antifungal agent, exhibits poor aqueous solubility and limited skin permeability, restricting its effectiveness in conventional topical formulations. Film-Forming Gels (FFGs) rep…

Nisha Shirkoli, Vinayak Mastiholimath

pp. 646–652 · DOI: 10.5530/jyp.20250213 · 2025

Background:This study is aimed to establish a novel and reliable UV-visible spectrophotometric method for simultaneous quantification of Adapalene and Erythromycin. Purpose:There is no documented Ultra Violet analysis fo…

Atul Desai, Hemshree Desai, Rutvij Desai, Anali Patel, Chirag Desai, Ankit Merai, Arindam Paul

pp. 653–660 · DOI: 10.5530/jyp.20251785 · 2025

Aim:This study aimed to evaluate the anti-gout activity of ACUPEN formulation using the Monosodium Urate (MSU)-induced gouty arthritis model and assess its Xanthine Oxidase (XO) inhibitory activity. Materials and Methods…