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In this issue
21–37 of 37Original Research Article(continued)
- Article
Juan Wu, Gui-lin Feng, Wei Li, Xue Zhao, Neng-sheng Bao, Tian-yu Ge, Xi Huang, Qing-quan Xue, He Zhang
pp. 640–650 · DOI: 10.1177/09731296251340845 · 2026
Background: Myocardial ischemia-reperfusion injury (MIRI) exacerbates thrombosis and platelet hyperactivation postrevascularization, with limited therapeutic efficacy of existing antiplatelet agents. Agkistrodon halys ve…
- Article
Mutee Murshed, Jameel Al-Tamimi, Hind Alzaylaee, Saleh Al-Quraishy
pp. 651–660 · DOI: 10.1177/09731296251391596 · 2026
Background: Plant products are a reliable source of traditional and contemporary medications. Objectives: This research investigates the impact that the Calotropis procera plant has on the Eimeria magna oocysts and sporo…
- Article
Zhen Fang, Xia Wang, Wenjing Bu, Hui Wang, Youqi Xu
pp. 661–668 · DOI: 10.1177/09731296251342376 · 2026
Background: Rectal cancer has a high morbidity and mortality rate in China, endangering public health. Sterol regulatory element-binding protein cleavage-activating protein/sterol regulatory element-binding protein 1 (SC…
- Article
Jiao Chen, Fengyun Wu, Yongyong Cai
pp. 669–678 · DOI: 10.1177/09731296251351747 · 2026
Background: Polygonatum polysaccharide has certain limitations in drug delivery and cellular uptake. To overcome these problems, polystyrene nanoparticles serve as an effective carrier to improve its bioavailability and …
- Article
Kaimin Lu, Mingliang Wu
pp. 679–689 · DOI: 10.1177/09731296251362994 · 2026
Background: Cynaropicrin (CYN) exhibits anti-inflammatory and anti-thrombotic properties, but its effects on pulmonary embolism (PE) are poorly understood. Objectives: This study aimed to investigate the effects of CYN o…
- Article
Haiyan Chen, Pu Zhang
pp. 690–701 · DOI: 10.1177/09731296251355768 · 2026
Background: Lung cancer is a notorious disease due to its high malignancy and complex metabolic adaptations, often regulated by the Akt/mTOR pathway. Objectives: This study investigates the anti-cancer potential of scopo…
- Article
Shuangju Liao, Huiqiong Huang, Yuan Tang
pp. 702–713 · DOI: 10.1177/09731296251360081 · 2026
Background: Ketamine, a commonly used anesthetic, plays a significant role during surgery, but its potential risk for neurotoxicity has drawn considerable attention. Objectives: This study was aimed to investigate the ef…
- Article
Yuan Kong, Yan Chen, Fei Sun, Sixue Qin, Liang Shi
pp. 714–724 · DOI: 10.1177/09731296251360559 · 2026
Background: Asthma is a chronic respiratory disease featured as destruction of epithelial tight junctions. In order to protect the functional integrity of airway epithelial cells, more active and effective prevention and…
- Article
Yongshuo Li, Bin Guo, Zixian Wang, Ting Wu
pp. 725–732 · DOI: 10.1177/09731296251364929 · 2026
Background: Oral cancer is a major type of head and neck cancer that mostly affects the lips, tongue, buccal mucosa, and salivary glands. It is a malignant tumor affecting the oral cavity with an annual incidence of over…
- Article
Maged E. Mohamed, Bander Aldhubiab, Nancy S. Younis
pp. 733–744 · DOI: 10.1177/09731296251361321 · 2026
Background: Eucalyptol, a terpenoid oxide isolated from the essential oil of several Eucalyptus species, exhibits numerous pharmacological actions. Myocardial infarction is a major reason for death worldwide, although ma…
- Article
Chengliang Zhang, Lidong Zhang, Lei Liu, Dajiang Song, Baolin Zhu
pp. 745–753 · DOI: 10.1177/09731296251365003 · 2026
Background: Spinal tuberculosis involves many complex mechanisms. Motherwort has anti-inflammatory, antioxidant, and anti-tumor activities, but its effect on spinal tuberculosis is unclear. Objectives: In this study, mot…
- Article
Pengxiang Wang, Xiaolin Sun, Jitao Sun, Feng Deng
pp. 754–764 · DOI: 10.1177/09731296251362995 · 2026
Background: In Alzheimer’s disease (AD), β-amyloid protein and the blood–brain barrier (BBB) are important factors in its pathogenesis. Research has found that resveratrol has a certain therapeutic effect on AD. It inhib…
- Article
Xuebin Xia, Yulong Xiong, Yuangao Liao, Jiajun Wang
pp. 765–772 · DOI: 10.1177/09731296251365468 · 2026
Background: Resveratrol (RV) plays a crucial part in regulating the development of the nervous system. Tet methylcytosine dioxygenase 2 (TET2) has an important physiological significance in the nervous system. TET2 perta…
- Article
Zhi Xu, Chunyan Liu, Mingwen Huang
pp. 773–781 · DOI: 10.1177/09731296251365720 · 2026
Background: Quercetin possesses anti-oxidative stress effect with potential in the treatment of tumor-related diseases. Whether it plays a role in liver cancer remains unclear. Objectives: This study aims to explore its …
- Article
Jiansui Xu, Xiaocun Zhang, Keyun Li, Rui Wan
pp. 782–793 · DOI: 10.1177/09731296251367539 · 2026
Background: Astragalus polysaccharide (APS), a component of traditional Chinese medicine, has recently shown promise in treating sarcopenia. Objectives: This study investigates APS’s potential to reduce reactive oxygen s…
- Article
Tianyu Lu, Qibin Li, Zengtao Wang
pp. 794–801 · DOI: 10.1177/09731296251367865 · 2026
Background: Maprotiline intervention is noted to alleviate the body’s inflammatory response effectively, but its specific molecular mechanism remains elusive. Objectives: This study aimed to investigate the impact of map…
- Article
Haiying Wei, Dan Zheng
pp. 802–812 · DOI: 10.1177/09731296251374434 · 2026
Background: As diabetes continues to be a global epidemic, the prevalence of retinopathy, a frequent microvascular complication, is anticipated to increase significantly. Effective management of blood glucose, blood pres…
