Table of Contents

Original Article

1. Article

   High performance liquid chromatography profiling of health‑promoting phytochemicals and evaluation of antioxidant, anti‑lipoxygenase, iron chelating and anti‑glucosidase activities of wetland macrophytes

   Keng‑Fei Ooh, Hean‑Chooi Ong, Fai‑Chu Wong, Nam‑Weng Sit, Tsun‑Thai Chai

   pp. 443–455 · DOI: 10.4103/0973-1296.139767 · 2014

   Background: The phytochemistry and bioactivity of wetland macrophytes are underexplored. Plants are known as the natural sources of phytochemical beneficial to health. Objective: The objective of this study is to analyze…

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2. Article

   Chemical constituents and toxicological studies of leaves from Mimosa caesalpiniifolia Benth., a Brazilian honey plant

   Nayana Bruna Nery Monção, Luciana Muratori Costa, Daniel Dias Rufino Arcanjo, Bruno Quirino Araújo, Maria do Carmo Gomes Lustosa, Klinger Antônio da França Rodrigues, Fernando Aécio de Amorim Carvalho, Amilton Paulo Raposo Costa, Antônia Maria das Graças Lopes Citó

   pp. 456–462 · DOI: 10.4103/0973-1296.139773 · 2014

   Background: Mimosa caesalpiniifolia Benth. (Leguminosae) is widely found in the Brazilian Northeast region and markedly contributes to production of pollen and honey, being considered an important honey plant in this reg…

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3. Article

   Anti‑melanogenic activity of the novel herbal medicine, MA128, through inhibition of tyrosinase activity

   mediated by the p38 mitogen‑activated protein kinases

   pp. 463–471 · DOI: 10.4103/0973-1296.139774 · 2014

   Background: Recently, our research group developed MA128, a novel herbal medicine, and demonstrated that MA128 is effective for the treatment of asthma and atopic dermatitis (AD). In particular, postinflammatory hyper‑pi…

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4. Article

   Ultra high performance liquid chromatography‑ ultraviolet‑electrospray ionization‑micrOTOF‑Q II analysis of flavonoid fractions from Jatropha tanjorensis

   Arun Kallur Purushothaman, Brindha Pemiah

   pp. 472–479 · DOI: 10.4103/0973-1296.139776 · 2014

   Background: Jatropha tanjorensis (Euphorbiaceae) an exotic traditional plant unique to Thanjavur district of Southern India also commonly called as Catholic vegetable. It has been used traditionally in decoctions for tre…

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5. Article

   Multiple shoot regeneration and effect of sugars on growth and nitidine accumulation in shoot cultures of Toddalia asiatica

   Chinthala Praveena, Ciddi Veeresham

   pp. 480–486 · DOI: 10.4103/0973-1296.139777 · 2014

   Background: Toddalia asiatica (Rutaceae) is an important medicinal plant in traditional medicinal system of India and China. Nitidine production from callus cultures of the plant had been investigated, but in vitro multi…

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6. Article

   Inhibition of inducible nitric oxide synthase and osteoclastic differentiation by Atractylodis Rhizoma Alba extract

   Sung‑Ho Choi, Sung‑Jin Kim

   pp. 494–500 · DOI: 10.4103/0973-1296.139780 · 2014

   Background: Atractylodis Rhizoma Alba (ARA) has been used in Korean folk medicine for constipation, dizziness, and anticancer agent. In the present study, we performed to test whether the methanolic extract of ARA has an…

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7. Article

   New steroidal saponin from Antigonon leptopus Hook. and Arn.

   Maria Karmella L. Apaya, Christine L. Chichioco‑Hernandez

   pp. 501–505 · DOI: 10.4103/0973-1296.139781 · 2014

   Background: Antigonon leptopus Hook. and Arn., Polygonaceae (cadena de amor), is a herbal remedy for pain and gout-like symptoms in the Philippines. The methanol extract of A. leptopus have shown strong inhibitory action…

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8. Article

   So‑Cheong‑Ryong‑Tang, a herbal medicine, modulates inflammatory cell infiltration and prevents airway remodeling via regulation of interleukin‑17 and GM‑CSF in allergic asthma in mice

   Hyung‑Woo Kim, Chi‑Yeon Lim, Bu‑Yeo Kim, Su‑In Cho

   pp. 506–511 · DOI: 10.4103/0973-1296.139784 · 2014

   Background: So‑Cheong‑Ryong‑Tang (SCRT), herbal medicine, has been used for the control of respiratory disease in East Asian countries. However, its therapeutic mechanisms, especially an inhibitory effect on inflammatory…

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9. Article

   Anticancer activity of flavane gallates isolated from Plicosepalus curviflorus

   Ghada Ahmed Fawzy, Areej Mohammad Al‑Taweel, Shagufta Perveen

   pp. 519–523 · DOI: 10.4103/0973-1296.139787 · 2014

   Background: Previous investigation of the methanol extract of Plicosepalus curviflorus leaves led to the isolation of two new flavane gallates (1, 2), together with other compounds including quercetin (3). The stems of P…

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10. Article

    Anticancer potential of Conium maculatum extract against cancer cells in vitro: Drug‑DNA interaction and its ability to induce apoptosis through ROS generation

    Jesmin Mondal, Ashis Kumar Panigrahi, Anisur Rahman Khuda-Bukhsh

    pp. 524–533 · DOI: 10.4103/0973-1296.139792 · 2014

    Objective: Conium maculatum extract is used as a traditional medicine for cervix carcinoma including homeopathy. However, no systematic work has so far been carried out to test its anti‑cancer potential against cervix ca…

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11. Article

    Euphorbia hirta accelerates fibroblast proliferation and Smad‑mediated collagen production in rat excision wound

    Aadesh Upadhyay, Pronobesh Chattopadhyay, Danswrang Goyary, Papiya M. Mazumder, Vijay Veer

    pp. 534–542 · DOI: 10.4103/0973-1296.139801 · 2014

    Background: Euphorbia hirta L. (Euphorbiaceae) is a traditional herbal medicine used for treatment of various diseases. Objective: E. hirta was investigated for in vitro/in vivo wound healing activity using human dermal …

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12. Article

    A new mulinane diterpenoid from the cushion shrub Azorella compacta growing in Perú

    Francisco Salgado, Carlos Areche, Beatriz Sepúlveda, Mario J. Simirgiotis, Fátima Cáceres, Cristina Quispe, Lina Quispe, Teresa Cano

    pp. 543–548 · DOI: 10.4103/0973-1296.139807 · 2014

    Background: Azorella compacta is a rare yellow‑green compact resinous cushion shrub growing from the high Andes of southern Perú to northwestern Argentina, and which is a producer of biologically active and unique diterp…

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13. Article

    Effect of three fatty acids from the leaf extract of Tiliacora triandra on P‑glycoprotein function in multidrug‑resistant A549RT‑eto cell line

    Chutima Kaewpiboon, Pakorn Winayanuwattikun, Tikamporn Yongvanich, Preecha Phuwapraisirisan, Wanchai Assavalapsakul

    pp. 549–556 · DOI: 10.4103/0973-1296.139779 · 2014

    Background: Cancer cells have the ability to develop resistance to chemotherapy drugs, which then leads to a reduced effectiveness and success of the treatment. Multidrug resistance (MDR) involves the resistance in the s…

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14. Article

    Strophanthus hispidus attenuates the Ischemia‑Reperfusion induced myocardial Infarction and reduces mean arterial pressure in renal artery occlusion

    Rohit Gundamaraju, Ravi Chandra Vemuri, Rajeev K Singla, Rishya Manikam, Ranga Rao A, Shamala Devi Sekaran

    pp. 557–562 · DOI: 10.4103/0973-1296.139782 · 2014

    Background: The myocardium is generally injured in the case of reperfusion injury and arterial damage is caused by hypertension. In reference to these statements, the present study was focused. Cardiac glycosides were sa…

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15. Article

    Hepatoprotective effects of Limonium tetragonum, edible medicinal halophyte growing near seashores

    Min Hye Yang, Na-Hyun Kim, Jeong-Doo Heo, Sang Hyun Sung, Eun Ju Jeong

    pp. 563–568 · DOI: 10.4103/0973-1296.139783 · 2014

    Background: During the process of hepatic fibrosis, the activation of hepatic stellate cells (HSCs) is responsible for the increased formation and reduced degradation of extracellular matrix in the liver. By employing th…

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16. Article

    The effects of extraction method on recovery rutin from Calendula officinalis L. (Asteraceae)

    Frederico Severino Martins, Edemilson Cardoso da Conceição, Elane Sousa Bandeira, José Otávio Carréra Silva Junior, Roseane Maria Ribeiro Costa

    pp. 569–573 · DOI: 10.4103/0973-1296.139785 · 2014

    Background: Calendula officinalis L. (Asteraceae) is a Mediterranean specie, but in Europe and America it is cultivated for ornamental or medicinal purposes. This species is widely used for presenting activities, antiinf…

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17. Article

    Chemical composition and hepatotoxic effect of Geranium schiedeanum in a thioacetamide‑induced liver injury model

    Juan Gayosso‑De‑Lucio, Mirandeli Bautista, C. Velazquez-González, De la O Arciniega M, J.A. Morales‑González, Juana Benedí

    pp. 574–580 · DOI: 10.4103/0973-1296.139788 · 2014

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18. Article

    Efficacy of ellagic acid and sildenafil in diabetes‑induced sexual dysfunction

    Sumanta Kumar Goswami, Manikanta Vishwanath, Suma Kallahalli Gangadarappa, Rema Razdan

    pp. 581–587 · DOI: 10.4103/0973-1296.139790 · 2014

    Background: Diabetes induced sexual dysfunction is a leading cause of male sexual disorder and an early indicator of cardiovascular complication. Reactive oxygen species generated in body during diabetes is a main causat…

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19. Article

    Anti‑inflammatory effect of Artemisiae annuae herba in lipopolysaccharide‑stimulated RAW 264.7 Cells

    You‑Chang Oh, Yun Hee Jeong, Taesoo Kim, Won‑Kyung Cho, Jin Yeul Ma

    pp. 588–595 · DOI: 10.4103/0973-1296.139793 · 2014

    Background: Artemisiae annuae herba (AAH) has been traditionally used as a drug for the treatment of malaria, heat stroke, bacterial infection, and fever in East‑Asia. Although AAH has been used for the treatment of infl…

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20. Article

    Bioassay‑guided isolation, identification and molecular ligand‑target insight of lipoxygenase inhibitors from leaves of Anisomeles malabarica R.Br.

    A. Sudha, P. Srinivasan

    pp. 596–605 · DOI: 10.4103/0973-1296.139795 · 2014

    Background: Anisomeles malabarica R. Br. (Lamiaceae) is extensively used in traditional medicine in major parts of India for several medicinal purposes, including their use in rheumatism. Materials and Methods: The air‑d…

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