Table of Contents

Original Article

1. Article

   Three statistical experimental designs for enhancing yield of active compounds from herbal medicines and anti‑motion sickness bioactivity

   Yan Chen, Cuiping Zhang, Mei Zhang, Xiaobing Fu

   pp. 435–443 · DOI: 10.4103/0973-1296.160444 · 2015

   Background: Since antiquity, Zingiber officinale (ginger), pogostemonis herba, and radix aucklandiae have been used as traditional Chinese medicines to remit gastrointestinal discomfort. Recent evidences also show the ef…

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2. Article

   Purification and characterization of an anticoagulant oligopeptide from Whitmania pigra Whitman

   Xiaobei Zheng, Juan Li, Zhengwang Chen, Yimei Liu, Keli Chen

   pp. 444–448 · DOI: 10.4103/0973-1296.160446 · 2015

   Background: Dried Whitmania pigra is used for the treatment of cardiovascular and cerebrovascular diseases in traditional Chinese medicine and hot water and alcohol extracts also have anticogulant activity. However, a lo…

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3. Article

   Anti‑aging effect of polysaccharide from Bletilla striata on nematode Caenorhabditis elegans

   Yusi Zhang, Ting Lv, Min Li, Ting Xue, Hui Liu, Weiming Zhang, Xiaoyu Ding, Ziheng Zhuang

   pp. 449–454 · DOI: 10.4103/0973-1296.160447 · 2015

   Background: Polysaccharide isolated from Bletilla striata, a well‑known traditional Chinese medicine (Bletilla striata polysaccharide [BSP]) has been found to play important roles in endothelial cells proliferation, indu…

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4. Article

   A study of pharmacokinetic interactions among co‑existing ingredients in Viscum coloratum after intravenous administration of three different preparations to rats

   Yuying Ma, Ronghua Fan, Mengmeng Duan, Zhiguo Yu, Yunli Zhao

   pp. 455–462 · DOI: 10.4103/0973-1296.160448 · 2015

   Background: Viscum coloratum (Komar) Nakai, known as Hujisheng in china, has been widely used as a herb medicine to treat a variety of diseases, including cardiovascular diseases, cancer, hypertension, hepatitis and hemo…

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5. Article

   Optimization of ultrasonic‑assisted extraction of antioxidant compounds from Guava (Psidium guajava L.) leaves using response surface methodology

   Fansheng Kong, Shujuan Yu, Zeng Feng, Xinlan Wu

   pp. 463–469 · DOI: 10.4103/0973-1296.160451 · 2015

   Objective: To optimization of extraction of antioxidant compounds from guava (Psidium guajava L.) leaves and showed that the guava leaves are the potential source of antioxidant compounds. Materials and Methods: The bioa…

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6. Article

   Selective and cost‑effective protocol to separate bioactive triterpene acids from plant matrices using alkalinized ethanol: Application to leaves of Myrtaceae species

   Adélia M. Belem Lima, Antonio Carlos Siani, Marcos Jun Nakamura, Luiz Antonio D’Avila

   pp. 470–476 · DOI: 10.4103/0973-1296.160453 · 2015

   Background: Triterpenes as betulinic (BA), oleanolic (OA) and ursolic acids (UA) have increasingly gained therapeutic relevance due to their wide scope of pharmacological activities. To fit large‑scale demands, exploitab…

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7. Article

   A direct protein kinase B‑targeted anti‑inflammatory activity of cordycepin from artificially cultured fruit body of Cordyceps militaris

   Ju Young Yoon, Ji Hye Kim, Kwang‑Soo Baek, Geum Soog Kim, Seung Eun Lee, Dae Young Lee, Je Hun Choi, Seung Yu Kim, Hyun Bong Park, Gi‑Ho Sung, Kang Ro Lee, Jae Youl Cho, Hyung Jun Noh

   pp. 477–485 · DOI: 10.4103/0973-1296.160454 · 2015

   Background: Cordyceps militaris is one of well-known medicinal mushrooms with anti-inflammatory, anti-cancer, anti-diabetic, and anti-obesity activities. Objective: The objective of the following study is to isolate chem…

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8. Article

   Traditional medicine yanggyuksanhwa‑tang inhibits adipogenesis and suppresses proliferator‑activated receptor‑gamma expression in 3T3‑L1 cells

   Soo‑Jin Jeong, Sae‑Rom Yoo, Chang‑Seob Seo, Hyeun‑Kyoo Shin

   pp. 502–508 · DOI: 10.4103/0973-1296.160456 · 2015

   Background: Yanggyuksanhwa‑tang (YGSHT) is a specific traditional Korean herbal formula for Soyangin according to Sasang constitutional philosophy. Although its biological activities against inflammation and cerebral inf…

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9. Article

   Region‑selective biosynthesis of artemisinic acid glycosides by crown galls of Panax quinquefolium and their in vitro antitumor activities

   Jianhua Zhu, Lijia Chen, Xianjing Hu, Liyan Song, Mingxuan Wang, Rongmin Yu

   pp. 518–523 · DOI: 10.4103/0973-1296.160460 · 2015

   Background: The biosynthesis of artemisinin derivatives is one of the interesting subjects. Artemisinic acid (AA) has been widely studied as a supposed intermediate in the biosynthetic pathway leading to artemisinin in A…

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10. Article

    Protective effect of calycosin‑7‑O‑β‑D‑glucopyranosi de against oxidative stress of BRL‑3A cells induced by thioacetamide

    Li Jian, Lin Xin, Ma Yufang, Huang Yifan

    pp. 524–532 · DOI: 10.4103/0973-1296.160461 · 2015

    Background: Calycosin‑7‑O‑β‑D‑glucopyranoside (CG) is a natural isoflavone found in traditional Chinese medicines Astragali Radix (AR). Objective: Calycosin‑7‑O‑β‑D‑glucopyranoside, an isoflavone isolated from AR, has be…

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11. Article

    The ethanolic extract of Juglans sinensis leaves and twigs attenuates CCl4‑induced hepatic oxidative stress in rats

    Heejung Yang, Sang Hyun Sung, Young Choong Kim

    pp. 533–539 · DOI: 10.4103/0973-1296.160463 · 2015

    Background: The nuts of Juglans sinensis Dode, walnut tree, are rich in unsaturated fatty acids and bioactive compounds with antioxidant activity on liver damages. However, hepatoprotective activity of the leaves and twi…

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12. Article

    Simultaneous quantification of crocetin esters and picrocrocin changes in Chinese saffron by high‑performance liquid chromatography‑diode array detector during 15 years of storage

    Yingpeng Tong, Yongqiu Yan, Xingyi Zhu, Ruoxi Liu, Feng Gong, Ling Zhang, Ping Wang

    pp. 540–545 · DOI: 10.4103/0973-1296.160467 · 2015

    Background: Saffron, which is made up of the dried stigmas of Crocus sativus L., has been successfully cultivated in China since 1970s and Zhejiang province is now the largest producing area in China, but the contents of…

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13. Article

    Microwave‑assisted extraction of polysaccharides from Yupingfeng powder and their antioxidant activity

    Dan Wang, Bi‑Bo Zhang, Xiao‑Xia Qu, Feng Gao, Min‑Yong Yuan

    pp. 546–554 · DOI: 10.4103/0973-1296.160468 · 2015

    Background: Microwave‑assisted reflux extraction of polysaccharides YPF-P from the famous Chinese traditional drug, Yupingfeng powder, optimization of extracting conditions and evaluation of their antioxidant activity we…

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14. Article

    Simultaneous determination of nine marker compounds in the traditional Korean medicine, Dangguisu‑san by high‑performance liquid chromatography

    Chang‑Seob Seo, Hyeun‑Kyoo Shin

    pp. 555–561 · DOI: 10.4103/0973-1296.160457 · 2015

    Background: Dangguisu-san (DGSS) has been widely used to treat ecchymosis, blood stagnation and pain resulting from physical shock in Korea. Objective: A high‑performance liquid chromatography– photodiode array detection…

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15. Article

    Simultaneous determination of three sesquiterpene lactones in Aucklandia lappa Decne by high‑performance liquid chromatography

    Chang‑Seob Seo, Hyeun‑Kyoo Shin

    pp. 562–566 · DOI: 10.4103/0973-1296.160471 · 2015

    Background: Aucklandia lappa Decne, a well‑known traditional herbal medicine, is used for the treatment of asthma, rheumatism, coughs, tuberculosis, and many other diseases. Objective: We performed simultaneous analysis …

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16. Article

    Total saponins from Discorea nipponica makino ameliorate urate excretion in hyperuricemic rats

    Qi Zhou, Dong-Hua Yu, Shu-Min Liu, Ying Liu

    pp. 567–573 · DOI: 10.4103/0973-1296.160442 · 2015

    Objective: The objective was to study the mechanism of reducing level of the uric acid by rhizoma dioscoreae nipponese. Materials and Methods: A total of 40 rats were divided into four groups: A normal group, hyperuricem…

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17. Article

    Optimization of induction, subculture conditions, and growth kinetics of Angelica sinensis (Oliv.) Diels callus

    Bing Huang, Lijuan Han, Shaomei Li, Chunyan Yan

    pp. 574–578 · DOI: 10.4103/0973-1296.160443 · 2015

    Background: Angelica sinensis (Oliv.) Diels is an important traditional Chinese medicine, and the medicinal position is its root. This perennial herb grows vigorously only in specific areas and the environment. Tissue cu…

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18. Article

    Neuroprotective activity of parawixin 10, a compound isolated from Parawixia bistriata spider venom (Araneidae: Araneae) in rats undergoing intrahippocampal NMDA microinjection

    Helene Aparecida Fachim, Marcia Renata Mortari, Leonardo Gobbo‑Netto, Wagner Ferreira dos Santos

    pp. 579–585 · DOI: 10.4103/0973-1296.160450 · 2015

    Background: Parawixia bistriata is a semi‑colonial spider found mainly in southeastern of Brazil. Parawixin 10 (Pwx 10) a compound isolated from this spider venom has been demonstrated to act as neuroprotective in models…

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19. Article

    Metabolic fingerprinting to understand therapeutic effects and mechanisms of silybin on acute liver damage in rat

    Qun Liang, Cong Wang, Binbing Li, Ai‑hua Zhang

    pp. 586–593 · DOI: 10.4103/0973-1296.160469 · 2015

    Background: Metabolic fingerprinting is a rapid and noninvasive analysis, representing a powerful approach for the characterization of phenotypes and the distinction of specific metabolic states due to environmental alte…

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20. Article

    Biological activities of Croton palanostigma Klotzsch

    Eduardo Ferreira Mota, Diele Magno Rosario, Andreza Socorro Silva Veiga, Davi Do Socorro Barros Brasil, Fernando Tobias Silveira, Maria Fâni Dolabela

    pp. 601–606 · DOI: 10.4103/0973-1296.160449 · 2015

    Background: Different species of Croton are used in traditional Amazonian medicine. Among the popular uses are treatment of bacterial diseases, poorly healing wounds and fevers. Objective: This study evaluated the antile…

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