Table of Contents

Original Article

1. Article

   In vitro Metabolism of Sodium 9‑dehydro‑17‑hydro‑ andrographolide‑19‑yl Sulfate in Rat Liver S9 by Liquid Chromatography–Mass Spectrometry Method

   Dongkun Zheng, Jun Shao, Weikang Chen, Yuehua Luo

   pp. S102–S108 · DOI: 10.4103/0973-1296.182194 · 2016

   Background: Sodium 9‑dehydro‑17‑hydro‑andrographolide‑19‑yl sulfate (DHAS) is the active ingredient of Xiyanping injection, a traditional Chinese medicine in clinical use. However, there has been no report about the meta…

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2. Article

   Effect of Procyanidin‑rich Extract from Natural Cocoa Powder on Cellular Viability, Cell Cycle Progression, and Chemoresistance in Human Epithelial Ovarian Carcinoma Cell Lines

   Shruti Taparia, Aparna Khanna

   pp. S109–S115 · DOI: 10.4103/0973-1296.182164 · 2016

   Background: Over the last 400 years, cocoa and chocolate have been described as having potential medicinal value, being consumed as a beverage or eaten as food. Concentration–dependant, antiproliferation, and cytotoxic e…

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3. Article

   Effect of Withinia Somnifera and Shilajit on Alcohol Addiction in Mice

   Priya Bansal, Sugato Banerjee

   pp. S121–S128 · DOI: 10.4103/0973-1296.182170 · 2016

   Background: Alcohol addiction is a social problem leading to both loss of health and economic prosperity among addicted individuals. Common properties of anti‑addictive compounds include anti‑anxiety, anticonvulsants, an…

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4. Article

   Flavonoids Derived from Abelmoschus esculentus Attenuates UV-B Induced Cell Damage in Human Dermal Fibroblasts Through Nrf2-ARE Pathway

   Juilee Patwardhan, Purvi Bhatt

   pp. S129–S138 · DOI: 10.4103/0973-1296.182175 · 2016

   Background: Ultraviolet‑B (UV‑B) radiation is a smaller fraction of the total radiation reaching the Earth but leads to extensive damage to the deoxyribonucleic acid (DNA) and other biomolecules through formation of free…

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5. Article

   Epicatechin Plus Treadmill Exercise are Neuroprotective Against Moderate‑stage Amyloid Precursor Protein/Presenilin 1 Mice

   Zhiyuan Zhang, Hao Wu, Houcai Huang

   pp. S139–S146 · DOI: 10.4103/0973-1296.182174 · 2016

   Background: Epidemiological evidence suggests that exercise and dietary polyphenols are beneficial in reducing Alzheimer’s disease (AD) risk. Materials and Methods: In the present study, 8 months old amyloid precursor pr…

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6. Article

   Protective Effect of High Molecular Weight Protein Sub‑fraction of Calotropis procera Latex in Monoarthritic Rats

   Priyanka Chaudhary, Marcio V. Ramos, Mirele da Silveira Vasconcelos, Vijay L. Kumar

   pp. S147–S151 · DOI: 10.4103/0973-1296.182151 · 2016

   Background: Proteins present in the latex of Calotropis procera have been shown to produce anti‑inflammatory effect and to afford protection in various disease models. Objectives: To determine the efficacy of high molecu…

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7. Article

   Reversed Phase High‑Performance Liquid Chromatographic Ultra‑violet (Photo Diode Array) Quantification of Oleanolic Acid and its Isomer Ursolic Acid for Phytochemical Comparison and Pharmacological Evaluation of Four Leucas Species Used in Ayurveda

   Pushpendra Kumar Shukla, Ankita Misra, Sharad Srivastava, Ajay K. S. Rawat

   pp. S159–S164 · DOI: 10.4103/0973-1296.182173 · 2016

   Objective: Evaluation of four industrially important Leucas species for their in vitro antidiabetic potential and radical scavenging effect along with high‑performance liquid chromatographic quantification of the bioacti…

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8. Article

   DNA Barcoding Identification of Kadsurae Caulis and Spatholobi Caulis Based on Internal Transcribed Spacer 2 Region and Secondary Structure Prediction

   Xiaoxue Yu, Zhiyong Xie, Junwei Wu, Junfei Tao, Xinjun Xu

   pp. S165–S169 · DOI: 10.4103/0973-1296.182162 · 2016

   Background: Kadsurae Caulis and Spatholobi Caulis have very similar Chinese names. Their commodities were hard to distinguish because their stems were very alike after dried and processed. These two herbal drugs were oft…

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9. Article

   Cardioprotective and Antioxidant Influence of Aqueous Extracts from Sesamum indicum Seeds on Oxidative Stress Induced by Cadmium in Wistar Rats

   Babatunji Emmanuel Oyinloye, Basiru Olaitan Ajiboye, Oluwafemi Adeleke Ojo, Sarah Onyenibe Nwozo, Abidemi Paul Kappo

   pp. S170–S174 · DOI: 10.4103/0973-1296.182155 · 2016

   Background: Oxidative stress has been implicated in the pathogenesis of several acute and chronic diseases of the heart as a result of indiscriminate exposure to cardiotoxic heavy metals. The study reported here was desi…

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10. Article

    Minimization of the Risk of Diabetic Microangiopathy in Rats by Nigella sativa

    Juraiporn Somboonwong, Mariem Yusuksawad, Somboon Keelawat, Sirima Thongruay, Ubon Poumsuk

    pp. S175–S180 · DOI: 10.4103/0973-1296.182169 · 2016

    Background: Microangiopathy is a chronic diabetic complication resulting from metabolic derangements, oxidative stress, and increased pro‑inflammatory cytokine production. Nigella sativa Linn. is used as an herbal medici…

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11. Article

    High Performance Liquid Chromatography‑mass Spectrometry Analysis of High Antioxidant Australian Fruits with Antiproliferative Activity Against Cancer Cells

    Joseph Sirdaarta, Anton Maen, Paran Rayan, Ben Matthews, Ian Edwin Cock

    pp. S181–S194 · DOI: 10.4103/0973-1296.182178 · 2016

    Background: High antioxidant capacities have been linked to the treatment and prevention of several cancers. Recent reports have identified several native Australian fruits with high antioxidant capacities. Despite this,…

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12. Article

    The Anticholinesterase Properties of Plants from the Northeast of Brazil Selected by an Ethnopharmacological Study for Disorders Relating to the Nervous System

    Valerium Thijan Nobre de Almeida e Castro, Tadeu Jose da Silva Peixoto Sobrinho, Allan Jonathan Chernichiarro Corrêa, Thiago Antonio de Sousa Araújo, Terezinha Gonçalves Da Silva, Elba Lucia Cavalcanti de Amorim

    pp. S195–S200 · DOI: 10.4103/0973-1296.182166 · 2016

    Background: Various factors may trigger Alzheimer’s disease and the cholinergic hypothesis, which is one of the most widely accepted, argues damage to the brain nuclei, may reduce the production of the choline acetyltran…

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13. Article

    S201 Intrathecal Injection of Resveratrol Attenuates Burn Injury Pain by Activating Spinal Sirtuin 1

    Wei Cheng, Jin‑Feng Wang, Cong‑Xian Yang, Liang Wu, Qin Yin, He Liu, Zhi‑Jian Fu

    pp. S201–S205 · DOI: 10.4103/0973-1296.182167 · 2016

    Objective: The present study sought to detect spinal sirtuin 1 (SIRT1) and acetylation of histone H3 (Ac‑H3) expression in rats with burn injury pain (BIP model). Procedures and Results: A BIP model was first established…

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14. Article

    Evaluation of Xanthine Oxidase Inhibitory Potential and In vivo Hypouricemic Activity of Dimocarpus longan Lour. Extracts

    Shi-Yuan Sheu, Yuan-Tsung Fu, Wen-Dar Huang, Yung-Ann Chen, Yi-Chih Lei, Chun-Hsu Yao, Feng-Lin Hsu, Tzong-Fu Kuo

    pp. S206–S212 · DOI: 10.4103/0973-1296.182176 · 2016

    Background: Longan is a fruit tree known to contain many phenolic components, which are capable of protecting people from oxidative damage through an anti‑inflammatory mechanism. It may be also worthwhile to study the ef…

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15. Article

    Ketosteroid Standardized Cissus quadrangularis L. Extract and its Anabolic Activity: Time to Look Beyond Ketosteroid?

    Atul N. Jadhav, Mohammed Rafiq, Rajendran Devanathan, Mohammed Azeemuddin, Suryakanth D. Anturlikar, Akhil Ahmed, Ramchandran Sundaram, U. V. Babu, Rangesh Paramesh

    pp. S213–S217 · DOI: 10.4103/0973-1296.182177 · 2016

    Background: Cissus quadrangularis (CQ) L. reported to contain 3‑ketosteroids and have bone health benefits. Aim: This study aimed at establishing the relationship between the ketosteroid content and anabolic as well as b…

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16. Article

    Pyrostegia venusta (Ker Gawl.) Miers Crude Extract and Fractions: Prevention of Dental Biofilm Formation and Immunomodulatory Capacity

    Mayara Brito de Sousa, José Otávio Carrera Silva Júnior, Wagner Luiz Ramos Barbosa, Erika da Silva Valério, Andriele da Mata Lima, Marlon Heggdorne de Araújo, Michelle Frazão Muzitano, Celso Vataru Nakamura, João Carlos Palazzo de Mello, Francisco Martins Teixeira

    pp. S218–S222 · DOI: 10.4103/0973-1296.182150 · 2016

    Background: Caries and periodontal diseases remain as important diseases in the Brazilian population. One important pathogen associated with this situation is Streptococcus mutans and other important factor is this patho…

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17. Article

    Phytochemicals from Tradescantia albiflora Kunth Extracts Reduce Serum Uric Acid Levels in Oxonate-induced Rats

    Wen-Ling Wang, Shi-Yuan Sheu, Wen-Dar Huang, Ya-Ling Chuang, Han-Chun Tseng, Tzann-Shun Hwang, Yuan-Tsung Fu, Yueh-Hsiung Kuo, Chun-Hsu Yao, Tzong-Fu Kuo

    pp. S223–S227 · DOI: 10.4103/0973-1296.182171 · 2016

    Background: Tradescantia albiflora (TA) Kunth (Commelinaceae) has been used for treating gout and hyperuricemia as folklore remedies in Taiwan. Therefore, it is worthwhile to study the effect of TA extracts on lowering u…

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18. Article

    Life Span and Motility Effects of Ethanolic Extracts from Sophora moorcroftiana Seeds on Caenorhabditis elegans

    Xin Li, Junxian Han, Rongyan Zhu, Rongrong Cui, Xingming Ma, Kaizhong Dong

    pp. S228–S230 · DOI: 10.4103/0973-1296.182152 · 2016

    Background: Sophora moorcroftiana is an endemic shrub species with a great value in folk medicine in Tibet, China. In this study, relatively little is known about whether S. moorcroftiana is beneficial in animals’ nervou…

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19. Article

    Chemopreventive Agents from Physalis minima Function as Michael Reaction Acceptors

    Ruizhi Men, Ning Li, Chihong Ding, Yingzhan Tang, Yachao Xing, Wanjing Ding, Zhongjun Ma

    pp. S231–S236 · DOI: 10.4103/0973-1296.182153 · 2016

    Background: The fruits of some varieties of genus Physalis have been used as delicious fruits and functional food in the Northeast of China. Materials and Methods: To reveal the functional material basis, we performed bi…

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20. Article

    Preparation and Evaluation of Andrographolide Solid Dispersion Vectored by Silicon Dioxide

    Dingkun Zhang, Junzhi Lin, Fang Zhang, Xue Han, Li Han, Ming Yang, Wenquan Zou

    pp. S245–S252 · DOI: 10.4103/0973-1296.182156 · 2016

    Background: Andrographolide (Andro) is a “natural antibiotic” as well as a typical insoluble drug. The purpose of this study was to investigate the feasibility of commercially available silica (SiO2) as a carrier of soli…

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