Table of Contents

Katharigatta N. Venugopala, Jasmine Chaudhary, Vishal Sharma, Akash Jain, Manish Kumar, Diksha Sharma, Pottathil Shinu, Bandar E. Aldhubiab, PranKishore Deb, Osama I. Alwassil, Mahesh Attimarad, Anroop B. Nair, Nagaraja Sreeharsha, Rashmi Venugopala, Mahmoud Kandeel, Christophe Tratrat, Wael El-Deeb, Michelyne Haroun, Mohamad Fawzi Mahomoodally, Viresh Mohanlall, Mohamed A. Morsy

pp. 791–807 · DOI: 10.4103/pm.pm_372_22 · 2022

Diabetes is a metabolic complication distinguished mainly by persistent hyperglycemia and is involved in the formation of reactive oxygen species, thereby causing oxidative stress, which is the major culprit for diabetic…

Syeda Nashvia Adin, Isha Gupta, Mohd. Aqil, Mohd. Mujeeb

pp. 808–814 · DOI: 10.4103/pm.pm_160_22 · 2022

Objectives: The study compares the efficacy of different modern and traditional methods for baicalin extraction. Box–Behnken design (BBD) was availed for optimization of process parameters for the extraction of baicalin …

Haeyeop Kim1,+, Laily Rahmawati1,+, Yo Han Hong, Su‑Young Choi, Jae Y. Cho

pp. 815–820 · DOI: 10.4103/pm.pm_40_22 · 2022

Background: Complex Great Powerful Blend (GPB) (a great powerful blend) is a hot water extract of three well‑known dried fruits: goji berry, mulberry, and jujube. These fruits have been used as food for a long time, and …

Darshit Ram, Devang Pandya

pp. 821–829 · DOI: 10.4103/pm.pm_544_21 · 2022

Objectives: Resistance developed by micro-organisms against antibiotics is now a global threat. There is a need to look at alternate sources from which substances useful against various diseases can be obtained. Soil sur…

Hamdan I. Almohammed, Abdullah D. Alanazi

pp. 830–835 · DOI: 10.4103/pm.pm_53_22 · 2022

Background: In recent years, increasing resistance to synthetic agents, their long‑term treatment, and lasting side effects, has faced many problems in treatment of leishmaniasis; so that finding a new high‑efficacy anti…

Bibhuti Bhusan Champati, Bhuban Mohan Padhiari, Asit Ray, Sudipta Jena, Ambika Sahoo, Jeetendranath Patnaik, Sujata Mohanty, Pradeep Kumar Naik, Pratap Chandra Panda, Sanghamitra Nayak

pp. 836–843 · DOI: 10.4103/pm.pm_51_22 · 2022

Objectives: Selection of elite germplasm for commercial cultivation was done by studying the variation of Shatavarin IV from different geographical regions. The development of simple and reliable high‑performance thin la…

Weijian Li, Changqing Lin, Zhonghong Chen

pp. 844–850 · DOI: 10.4103/pm.pm_87_22 · 2022

Objectives: In the present study, the in vitro anticancer effects of globularifolin were evaluated against human lung cancer and attempts were made to explore the underlying molecular mechanisms. Materials and Methods: C…

Seong‑Wook Seo, Sang‑Cheol Im, Kyoung Kim

pp. 851–858 · DOI: 10.4103/pm.pm_46_22 · 2022

Objectives: Accordingly, the current study was performed to evaluate the effects and the underlying mechanisms of CP on dexamethasone (DEX)‑provoked muscle atrophy in C57BL/6 mice. Materials and Methods: The 8‑week‑old m…

Xiang Wang, Qingqing Ding, Tongshan Wang, Weiping Xie, Mao Huang

pp. 859–870 · DOI: 10.4103/pm.pm_439_21 · 2022

Background: This research explored the effects of vinorelbine combined with oxaliplatin on non‑small cell lung cancer (NSCLC). Materials and Methods: NSCLC cells were treated with vinorelbine, oxaliplatin, and insulin‑li…

Xiaoyan Wang, Lihong Liu, Huilan Zhang, Xiaoyan Liu, Hui Liu

pp. 871–878 · DOI: 10.4103/pm.pm_173_22 · 2022

Objectives: We induced epilepsy in zebrafish through the administration of pentylenetetrazole as a model organism. Materials and Methods: To assess the anti‑epileptic potency of plant extract, behavioural changes were re…

Wei Ding, Yuan Fang, Fei Fan, Bibo Lei, Mingqiang Zhang, Hui Yong

pp. 879–885 · DOI: 10.4103/pm.pm_215_22 · 2022

Objectives: Pain or nociception is a devastating experience that alters both the physiological and psychological status of individuals. A variety of chemical and physiological tissue damage and physical parameters like t…

Sandeep R. Pai, Parthraj R. Kshirsagar, Nilesh V. Pawar, Mansingraj S. Nimbalkar

pp. 886–892 · DOI: 10.4103/pm.pm_77_22 · 2022

Aim: The study herein was performed in view of prospecting 15 species and one variety of Barleria in comparison to Adathoda vasica for phytochemical composition, and antioxidant activities. Materials and Methods: In addi…

Abdulrahman Alsultan, Mohammad Aatif, Ghazala Muteeb

pp. 893–902 · DOI: 10.4103/pm.pm_195_22 · 2022

Background: Antibiotic resistance in bacteria mediated by New Delhi Metallo‑β‑lactamase (NDM) is a global threat to human health with an enormous economic burden. NDM can hydrolyze all the β‑lactam core‑containing antibi…

Huibo Guan, Miao Yu, Yanyan Zhou, Xinmin Yao

pp. 903–910 · DOI: 10.4103/pm.pm_375_21 · 2022

Background: In this study, we elucidated the neuroprotective effect of dioscin, a plant‑derived steroidal saponin utilized in Chinese medicine to treat various diseases. To achieve this, we established the aluminum chlor…

Sandip Ashok Murtale, Prakash S. Goudanavar, N. Raghavendra Naveen, Walaa F. Alsanie, Majid Alhomrani, Abdulhakeem S. Alamri, Syed Mohammed Basheeruddin Asdaq, Md.Khalid Anwer, Nagaraja Sreeharsha, Mazen Al Gharsan, Santosh Fattepur

pp. 911–918 · DOI: 10.4103/pm.pm_161_22 · 2022

Objectives: Natural polymers are chosen over semisynthetic and synthetic excipients due to their lack of toxicity, low cost, availability, soothing action, and nonirritant nature, as well as their ability to undergo a va…

Xiaoping Yang, Vidya Devanathadesikan Seshadri, Jianfei Zhang

pp. 919–925 · DOI: 10.4103/pm.pm_219_22 · 2022

Background: Cancer, a deadly disease seems to be a major concern for the global medical field. Controlling the spread of disease is not only a problem for under developed countries but also the developed countries face a…

Jianrui Chen, Wei Liang, Hao Li, Jianzhong Huo

pp. 926–931 · DOI: 10.4103/pm.pm_287_22 · 2022

Background: Osteoarthritis (OA) is a major bone‑related disease, which is characterized by joint deterioration, bone destruction, and whole joint damage, leading to permanent disability. The present study aimed to assess…

Xue Liang, Ziquan Lan, Yiqiao Huang, Ganggang Jiang, Ting Liu

pp. 932–939 · DOI: 10.4103/pm.pm_296_21 · 2022

Objectives: Formononetin is a natural isoflavone compound and has been reported to have anti‑cancer properties. However, the mechanism by which formononetin inhibits hormone‑resistant prostate cancer (PCa) has not been r…

Oumaima Boutoub, Smail Aazza, Soukaina El‑Guendouz, Lahsen El Ghadraoui, Maria G. Miguel

pp. 940–952 · DOI: 10.4103/pm.pm_2_22 · 2022

Objectives: The aerial part of two plant samples (Euphorbia resinifera and Euphorbia officinarum) collected in Morocco was examined for the solvent effect, extraction time, and plant concentration in order to determine t…

Rakesh Pandit Dhavale, Swapnil Sanjay Patil, Sagar Ujwal Jadhav, Rushikesh Pandit Dhavale, Sachin Bharat Agawane

pp. 953–961 · DOI: 10.4103/pm.pm_356_21 · 2022

Objectives: The synthesis of Fe‑NPs using Sphagneticola trilobata leaf extract using ferric chloride solution and its biological assessment. Materials and Methods: The present study involved the synthesis of Fe‑NPs using…