Table of Contents

pp. 823–830 · DOI: 10.1177/09731296251383290 · 2026

Diabetes mellitus, a chronic condition marked by elevated blood glucose levels, has become a global health concern, requiring effective and sustainable treatments. 1-Deoxynojirimycin (DNJ), an iminosugar primarily found …

Li Fang, Lu Zhang, Mengyao Shi, Cheng Yang, Jiabing Tong, Yating Gao, Zegeng Li

pp. 831–841 · DOI: 10.1177/09731296251364981 · 2026

Background and Objectives: Chronic inflammation resulting from cigarette smoke extract (CSE) is frequently driven by activation of the high mobility group box 1 (HMGB1)–toll-like receptor 4 (TLR4)–nuclear factor kappa B …

Shengjie Chen, Xinxin Zhou, Jiaohui Yang, Wei Xu

pp. 842–849 · DOI: 10.1177/09731296251384061 · 2026

Background and Objectives: Gui-Zhi (Cinnamomi ramulus) and Shao-Yao (Paeoniae radix Alba) are traditional Chinese medicinal herbs with well-documented analgesic and antispasmodic properties. This study explores the effic…

Shiya Li, Fang Qian, Huili Wu, Chen Tang, Lijuan Wang

pp. 850–860 · DOI: 10.1177/09731296251384058 · 2026

Background and Objectives: Plumbagin (PLB), a natural compound derived from Plumbago zeylanica L., exhibits potent antioxidant, anti-inflammatory, antibacterial, and anticancer properties. However, its role in modulating…

Yuanyuan Song, Chen Cheng, Ying Liu, Jin Cheng, Heng Li, Yanyun Zhao

pp. 861–871 · DOI: 10.1177/09731296251384068 · 2026

Background: Chuanxing Qingfei Tangjiang (CQT) is a classic traditional Chinese medicine (TCM) formulation composed of nine herbal components: Mentha haplocalyx (Bohe), Glycyrrhiza uralensis (Gancao), Eriobotrya japonica …

Abdullah A. Alarfaj, Abdurahman H. Hirad, Akon Higuchi, Murugan A. Munusamy, Suresh Kumar Subbiah

pp. 872–884 · DOI: 10.1177/09731296251391939 · 2026

Background: Nanotechnology based research offers a favorable method to address breast cancer and bacterial resistance, two serious global health challenges. Breast cancer is one of the most commonly diagnosed tumors glob…

Weiwei Yuan, Hongtao Tan, Huihui Li, Junxian Chen, Jun Qiu

pp. 885–897 · DOI: 10.1177/09731296251325348 · 2026

Background: Chronic obstructive pulmonary disease (COPD) is a common inflammatory disorder that is significantly aggravated by tobacco smoke exposure. Objectives: This study aimed to explore the effect of glabridin (Glab…

Xueyin Wang, Yanwu Jin, Yingui Sun

pp. 898–908 · DOI: 10.1177/09731296251384048 · 2026

Background and Objectives: To systematically evaluate the therapeutic potential and underlying mechanisms of Tripterygium wilfordii Hook F. (TwHF) and its active constituents, particularly celastrol and triptolide, in au…

Xiaoyue Zhang, Junqin Wang, Xiaojuan Shen, Yaqin Shen, Xiaomei Zhang, Chenlu Zhu

pp. 909–917 · DOI: 10.1177/09731296251396308 · 2026

Background: 5-Fluorouracil (5-FU) is a classic chemotherapy drug. Iron oxide nanocarriers (Fe3O4-NPs) significantly increase 5-FU concentration at tumor sites by enhancing targeting and sustained-release properties, whil…

Yuxiao Zeng, Tao Lian, Jian Li, Yongwei Zhuang

pp. 918–924 · DOI: 10.1177/09731296251400050 · 2026

Background: Qijiao Shengbai Capsule is a traditional multi-herb formulation composed of natural products including Jujube (Ziziphus jujuba), Donkey-hide gelatin (Colla corii asini), Pseudostellaria heterophylla, Epimediu…

Xueling Liang, Xiaojie Zhang, Yanhong Qin

pp. 925–932 · DOI: 10.1177/09731296251408896 · 2026

Background: Pediatric Dingchuan Oral Liquid (PDOL) is a traditional Chinese polyherbal formulation widely used in the clinical treatment of pediatric asthma. It comprises 11 medicinal ingredients, including Ephedra sinic…

Xiaofei Wang, Shiqin Wang, Jin Li, Chen Ma

pp. 933–943 · DOI: 10.1177/09731296251384414 · 2026

Background: Oral squamous cell carcinoma (OSCC) signifies a major global health issue, defined by its destructive nature and often delayed diagnosis, leading to suboptimal prognoses. The global case and mortality rates o…

Na Ri Choi, Seok-Jae Ko, Woo-Gyun Choi, Joo Hyun Nam, Jae-Woo Park, Byung Joo Kim

pp. 944–953 · DOI: 10.1177/09731296251388725 · 2026

Background: Irritable bowel syndrome (IBS) is a common functional disorder of the gastrointestinal (GI) tract, typically presenting with abdominal discomfort, distension, and irregular bowel movements. In IBS, the underl…

Gaiyan Li, Man Li

pp. 954–963 · DOI: 10.1177/09731296251385797 · 2026

Background: Gastric ulcers, a predominant type of peptic ulcer disease, are defined by lesions in the stomach lining that extend into the muscularis mucosa. Optimal management of gastric ulcers requires a multidisciplina…

Qiaolin Wang, Jingjing Cheng

pp. 964–973 · DOI: 10.1177/09731296251391924 · 2026

Background: Osajin (OSJ), a prenylated isoflavone from Maclura pomifera, has specific ethnobotanical or traditional medicinal uses. While its role in oxidative stress modulation is established, its efficacy in preventing…

Zhongting Pan, Yanling Guo

pp. 974–985 · DOI: 10.1177/09731296251391926 · 2026

Background: Gastric cancer remains a major global health challenge, with approximately 1.1 million new cases and 770,000 deaths reported annually. Despite ongoing advancements in therapeutics, the prognosis for patients …

Hongyan Zhang, Kun Zhang

pp. 986–997 · DOI: 10.1177/09731296251396330 · 2026

Background: Stroke, a formidable global health issue, is characterized by high disability and mortality rates, thus necessitating advances in acute treatment strategies and preventative medical regimens. Ischemic stroke …

Mei Tsz Lai, Siu Kan Law, Sze Wing Ng, Yanping Wang, Xiao Xiao Wu

pp. 998–1008 · DOI: 10.1177/09731296251384395 · 2026

Background: Many cosmetic products possess antioxidant and anti-bacterial properties. However, they are chemically synthesized products. This research project focuses on “organic” and “natural” for skin care products. “O…

Rinka Juneja, Deepti Mathpal, Bimlesh Kumar, Amir Saeed, Khalid Alshaghdali, Fahad Aldakheel, Mohd Salih, Raja Rezgyi, Mohd Saeed, Vishal M. Balramnavar

pp. 1009–1019 · DOI: 10.1177/09731296251384413 · 2026

Background: Rohitukine (RH) in Benzo[α]pyrene, an experimental model of cognitive and memory impairment, has not been reported yet. Hence, with the state of the art in repurposing techniques, we redefined the use of RH a…

Juan Xu, Qiong Liu, Qiong Pan

pp. 1020–1027 · DOI: 10.1177/09731296251398962 · 2026

Background: Cervical cancer continues to pose a considerable global health concern, disproportionately impacting women in low- and middle-income nations due to various barriers. Although mostly preventable with immunizat…