Table of Contents

Khemkaran Ahirwar, Junaid Khan, Anand Kumar, Mukesh Nag

pp. 7–16 · DOI: 10.1177/09731296251330393 · 2026

Background: The medicinal properties of plants and plant derivatives have led to their long-term use in medicine. Objectives: The present review article was drafted to discuss the traditional importance of Cordia macleod…

Zhenhai Cai, Jieen Pan, Xiaojun He, Wenmin Wang, Zhengwei Zhou

pp. 17–29 · DOI: 10.1177/09731296241305887 · 2026

Osteosarcoma (OS) is a predominant malignancy among children and adolescents, ranked third in frequency after lymphoma and leukemia. It presents a significant risk of metastasis, particularly to the lungs and distal bone…

Lu Li, Xuxi Chen, Yufei Xue, Weiyi Chen

pp. 30–42 · DOI: 10.1177/09731296251324704 · 2026

Background: Periodontitis is a persistent inflammatory condition that mainly affects the supportive tissues of the teeth, comprising the gingiva, periodontal ligament, and alveolar bone. Objectives: The present study foc…

Shujing Qi, Gaixia Fu, Zhaozhen Chu

pp. 43–52 · DOI: 10.1177/09731296251330001 · 2026

Background: Anorexia–cachexia syndrome in head and neck cancer (ACSHNC) seriously affects the patient’s quality of life and prognosis. Curcumin inhibits head and neck cancer and anorexic cachexia syndrome. S100A9 is rela…

Amir Mahgoub Awadelkareem, Abd Elmoneim O. Elkhalifa, Mohd Adnan, Mohammed Kuddus, Mohammed Idreesh Khan, Manojkumar Sachidanandan, Fauzia Ashfaq, Mirza Sarwar Baig, Syed Amir Ashraf

pp. 53–66 · DOI: 10.1177/09731296251322233 · 2026

Background: Breast cancer remains a significant global health challenge despite the emergence of various drug molecules. However, the adverse side effects of several drugs and chemotherapy necessitate the exploration of …

Yezhou Li, Chengjian Tang

pp. 67–79 · DOI: 10.1177/09731296251323311 · 2026

Background and Objectives: Alginate and gelatin have biocompatibility and biodegradability for drug formulations or carriers, but the roles and mechanisms in cartilage injury (CI) repair remain unclear. This research inv…

Baoping Duan, Hongyan Ge, Meng Sun, Sheng Su, Shiqiang Zhao, Ping Liu

pp. 80–89 · DOI: 10.1177/09731296251325353 · 2026

Background: Diabetic cataract, an ocular complication arising from diabetes, can lead to damage to ocular tissues, particularly affecting the lens and causing symptoms such as blurred vision. Objectives: This work aimed …

Bin Zhang, Xinghui Ren, Juan Wang, Wei Zhang

pp. 90–98 · DOI: 10.1177/09731296251325329 · 2026

Background: Allicin has anti-tumor activity and an inhibitory effect on lung cancer. Objectives: In this experiment, lung cancer mice were used as the research subjects to explore the mechanism of allicin with cisplatin …

Yaming Li, Jiayin Liu, Shuang Pan

pp. 99–112 · DOI: 10.1177/09731296251324741 · 2026

Background: Benzo[a]pyrene (B[a]P), a polycyclic aromatic hydrocarbon exposure, is a major public health issue globally, particularly as a result of its connection to lung cancer. Individuals exposed to higher levels of …

Huan Hui, Fan Li

pp. 113–124 · DOI: 10.1177/09731296251322829 · 2026

Background: Epilepsy is a complex neurological condition characterized by recurrent seizures due to abnormal neuronal activity. Objectives: The major aim of this study is to examine the therapeutic activities of leonurin…

Siddig Ibrahim Abdelwahab, Manal Mohamed Elhassan Taha, Syam Mohan, Mukul Sharma, Md Shamsher Alam, Mohamed Eltaib Elmobark, Sivakumar S Moni, Mohammed Albeishy, Ohood Sufyani, Afraim Koty, Adel S. Al-Zubairi

pp. 125–135 · DOI: 10.1177/09731296251324742 · 2026

Background: This study conducted a comprehensive comparative analysis of Cheilocostus speciosus (sea qust) and Saussurea lappa (Indian qust) using various bioanalytical techniques. Objectives: To identify the undiscovere…

Yulong Li, Xiang Li

pp. 136–146 · DOI: 10.1177/09731296251323316 · 2026

Background: Myocardial ischemia/reperfusion (I/R) injury refers to myocardial tissue damage caused by blood reperfusion after acute heart ischemia caused by coronary artery thrombosis and others. This process is closely …

Jie Yang, Xinrong Zhang, Jiawei Zhang, Lu Yan

pp. 147–157 · DOI: 10.1177/09731296251342290 · 2026

Background: Diabetes mellitus, a persistent metabolic disorder defined by elevated blood glucose, poses a global public health challenge. One of the most debilitating complications of this disease is the progression of c…

Xiaoli Yuan

pp. 158–166 · DOI: 10.1177/09731296251362609 · 2026

Background: Parkinson’s disease (PD) is a prevalent age-associated neurodegenerative disorder, primarily characterized by dopaminergic neuronal loss, oxidative stress, and microglia-mediated neuroinflammation. Current th…

Yang Li, Yan Zhao, Rou Shi, Yan Li, Yun-Yun Chen, Zhu Zhou, Hui-Fang Li

pp. 167–177 · DOI: 10.1177/09731296251361610 · 2026

Background: Diabetic nephropathy (DN) is a common microvascular complication of diabetes and its currently the leading cause of end-stage renal disease worldwide. Reducing its incidence and delaying its progression are u…

Nehru Sai Suresh Chalichem, Min-Jung Kim, Tae-Jong Kim, Seung-Un Kim, Prasanna Raja, Mohammed S. Khan

pp. 178–193 · DOI: 10.1177/09731296251326792 · 2026

Background: Osteoarthritis affects millions of people worldwide. Currently, available pharmacological treatment is limited to topical and oral non-steroidal anti-inflammatory drugs (NSAIDs). Several studies have reported…

Meikang Peng, Tao Chen, Hongliang Peng

pp. 194–202 · DOI: 10.1177/09731296251325350 · 2026

Background: There is an abnormal enhancement of androgen receptor activity in prostate cancer cells, leading to increased sensitivity to androgens and the promotion of cancer cell proliferation. Objectives: This study ai…

Jianjiang Luo, Lixia Wang, Yongwei Zhao, Huifang Liu, Dan Xu, Fengsen Li

pp. 203–216 · DOI: 10.1177/09731296251325347 · 2026

Background: Cough variant asthma (CVA) is a distinct type of asthma manifested as dysregulation of fluid metabolism and modulation of ferroptosis. Objectives: The aim of this study was to demonstrate the regulatory effec…

Mingyan He, Ru Liu, Yalin Li, Qi Zhang

pp. 217–222 · DOI: 10.1177/09731296251325341 · 2026

Background: Myocardial ischemia-reperfusion (MI/R) injury is a leading cause of myocardial damage, characterized by apoptosis and impaired cardiac function. Dezocine, a mixed opioid receptor agonist/antagonist, has shown…

Ping Ren, Rongjuan Xi

pp. 223–234 · DOI: 10.1177/09731296251330715 · 2026

Background: Pneumonia is a serious respiratory illness that impacts the lungs, leading to inflammation and fluid accumulation in the alveoli, the tiny air sacs essential for gas exchange. Mycoplasma pneumonia is a severe…