Table of Contents

Original Article

1. Article

   New free radical scavenging neolignans from fruits of Piper attenuatum

   S. Divya Reddy, Bandi Siva, B. Poornima, D. Anand Kumar, Ashok K. Tiwari, U. Ramesh

   pp. 235–241 · DOI: 10.4103/0973-1296.153063 · 2015

   Objective: The aim was to study and identify free radicals scavenging and antihyperglycemic principles in fruit of Piper attenuatum. Materials and Methods: Bioassay guided identification of extracts possessing potent fre…

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2. Article

   Anti‑arthritic activity of Fu‑Fang‑Lu‑Jiao‑Shuang on collagen‑induced arthritis in Balb/c mice and its underlying mechanisms

   Yanyan Wang, Weiguang Sun, Laxia Chen, Xin Xu, Yunxia Wu, Jinwen Zhang, Yonghui Zhang

   pp. 242–249 · DOI: 10.4103/0973-1296.153065 · 2015

   Background: Rheumatoid arthritis (RA) is a common, autoimmune disorder characterized by progressive multiple joint destruction, deformity, disability and premature death in most patients. Fu‑Fang‑Lu‑Jiao‑Shuang (FFLJS) i…

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3. Article

   Shikonin induces apoptosis in the human gastric cancer cells HGC‑27 through mitochondria‑mediated pathway

   Yue Hou, Jinghua Xu, Xia Liu, Xichun Xia, Ning Li, Xiuli Bi

   pp. 250–256 · DOI: 10.4103/0973-1296.153074 · 2015

   Background: Gastric cancer (GC) is one of the most frequently occurring digestive tract cancers and fewer chemotherapeutic drugs for GC have shown promising results. In this study, we investigated the anti-tumor activity…

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4. Article

   The enriched fraction of Elephantopus scaber Triggers apoptosis and inhibits multi‑drug resistance transporters in human epithelial cancer cells

   Asmy Appadath Beeran, Naseer Maliyakkal, Chamallamudi Mallikarjuna Rao, Nayanabhirama Udupa

   pp. 257–268 · DOI: 10.4103/0973-1296.153077 · 2015

   Background: Medicinal plants have played an important role in the development of clinically useful anticancer agents. Elephantopus scaber (Asteraceae) (ES) is widely used in Indian traditional system of medicine for the …

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5. Article

   Methyl gallate isolated from Spondias pinnata exhibits anticancer activity against human glioblastoma by induction of apoptosis and sustained extracellular signal‑regulated kinase 1/2 activation

   Dipankar Chaudhuri, Nikhil Baban Ghate, Sudhir Shankar Singh, Nripendranath Mandal

   pp. 269–276 · DOI: 10.4103/0973-1296.153078 · 2015

   Background: Spondias pinnata has been reported for its efficient anticancer effects, but the studies were mostly focused on its extract. Objective: Since its bioactive compounds are largely unknown, this study was design…

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6. Article

   Comparative evaluation of standardized alcoholic, hydroalcoholic, and aqueous extracts of Phyllanthus maderaspatensis Linn. against galactosamine‑induced hepatopathy in albino rats

   U. K. Ilyas, Deepshikha P. Katare, Vidhu Aeri

   pp. 277–282 · DOI: 10.4103/0973-1296.153079 · 2015

   Background: Phyllanthus maderaspatensis species (Euphorbiaceae) has been used in folk medicine of many countries as a remedy against several pathological conditions including jaundice and hepatitis. This study is an atte…

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7. Article

   Attenuation of reactive oxygen/nitrogen species with suppression of inducible nitric oxide synthase expression in RAW 264.7 macrophages by bark extract of Buchanania lanzan

   Shailasree Sekhar, K. K. Sampath-Kumara, S. R. Niranjana, H. S. Prakash

   pp. 283–291 · DOI: 10.4103/0973-1296.153080 · 2015

   Background: Oxidative stress is one of the most critical factors implicated in disease conditions. Buchanania lanzan Spr. (Anacardiaceae) bark powder preparation has been reported for treating an inflammatory condition i…

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8. Article

   Preconditioning with glycyrrhizic, ferulic, paeoniflorin, cinnamic prevents rat hearts from ischemia/reperfusion injury via endothelial nitric oxide pathway

   Guo-Qiang Qian, Jingjing Ding, Xiaozhao Zhang, Xiaofeng Yin, Yuqin Gao, Guo-Ping Zhao

   pp. 292–296 · DOI: 10.4103/0973-1296.153081 · 2015

   Objective: The objective was to investigate the endothelial nitric oxide synthase (eNOS/NO) pathway is involved or not in the protective effects of glycyrrhizic, ferulic, paeoniflorin, cinnamic (GFPC) in myocardial ische…

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9. Article

   Simultaneous determination three phytosterol compounds, campesterol, stigmasterol and daucosterol in Artemisia apiacea by high performance liquid chromatography‑diode array ultraviolet/visible detector

   Jiwoo Lee, Jin Bae Weon, Bo‑Ra Yun, Min Rye Eom, Choong Je Ma

   pp. 297–303 · DOI: 10.4103/0973-1296.153082 · 2015

   Background: Artemisia apiacea is a traditional herbal medicine using treatment of eczema and jaundice in Eastern Asia, including China, Korea, and Japan. Objective: An accurate and sensitive analysis method using high pe…

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10. Article

    A new method for identification of natural, artificial and in vitro cultured Calculus bovis using high‑performance liquid chromatography‑mass spectrometry

    Yonggang Liu, Peng Tan, Shanshan Liu, Hang Shi, Xin Feng, Qun Ma

    pp. 304–310 · DOI: 10.4103/0973-1296.153083 · 2015

    Objective: Calculus bovis have been widely used in Chinese herbology for the treatment of hyperpyrexia, convulsions, and epilepsy. Nowadays, due to the limited source and high market price, the substitutes, artificial an…

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11. Article

    Effects of Pogostemon cablin Blanco extract on hypoxia induced rabbit cardiomyocyte injury

    Chi‑Yeon Lim, Bu‑Yeo Kim, Se‑Hyun Lim, Su‑In Cho

    pp. 311–319 · DOI: 10.4103/0973-1296.153084 · 2015

    Background: Pogostemonis Herba, the dried aerial part of Pogostemon cablin Blanco, is a well‑known materia medica in Asia that is widely used for syndrome of gastrointestinal dysfunctions. Objective: This study was under…

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12. Article

    Quantitative analysis of the eight major compounds in the Samsoeum using a high‑performance liquid chromatography coupled with diode array detection and electrospray ionization mass spectrometer

    Jin Bae Weon, Hye Jin Yang, Bohyoung Lee, Jin Yeul Ma, Choong Je Ma

    pp. 320–326 · DOI: 10.4103/0973-1296.153085 · 2015

    Background: Samsoeum was traditionally used for treatment of a respiratory disease. Objective: The simultaneous determination of eight major compounds, ginsenoside Rg3, caffeic acid, puerarin, costunolide, hesperidin, na…

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13. Article

    Sesamol, a lipid lowering agent, ameliorates aluminium chloride induced behavioral and biochemical alterations in rats

    Jessy John, Madhavan Nampoothiri, Nitesh Kumar, Jayesh Mudgal, Gopalan Kutty Nampurath

    pp. 327–336 · DOI: 10.4103/0973-1296.153086 · 2015

    Background: Sesame oil from the seeds of Sesamum indicum Linn. (Pedaliaceae) has been used traditionally in Indian medical practice of Ayurveda in the treatment of central nervous system disorders and insomnia. A few pub…

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14. Article

    The influences of inorganic elements in soil on the development of famous ‑ region Atractylodes lancea (Thunb.) DC

    Weiwanqi Zhang, Zhen Ouyang, Ming Zhao, Yuan Wei, Huasheng Peng, Qiang Wang, Ling Guo

    pp. 337–344 · DOI: 10.4103/0973-1296.153087 · 2015

    Background: Atractylodes lancea (Thunb.) DC., is an important medicinal plant in China. Recently, researches of A. Lancea were focused on chemical composition and genetics, only a few were concerned with soil factors. Ob…

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15. Article

    Ethyl acetate extract from marine sponge Hyattella cribriformis exhibit potent anticancer activity by promoting tubulin polymerization as evidenced mitotic arrest and induction of apoptosis

    Pazhanimuthu Annamalai, Malini Thayman, Sowmiya Rajan, Lakshmi Sundaram Raman, Sankar Ramasubbu, Pachiappan Perumal

    pp. 345–355 · DOI: 10.4103/0973-1296.153088 · 2015

    Background: Marine sponges are important sources of bioactive compounds. Objective: This study investigated the anticancer properties of Hyattella cribriformis ethyl acetate (EA) fraction in various cancer and normal cel…

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16. Article

    Identification of longevity, fertility and growth‑promoting properties of pomegranate in Caenorhabditis elegans

    Hasan Kılıçgün, Nazlı Arda, Evren Önay Uçar

    pp. 356–359 · DOI: 10.4103/0973-1296.153089 · 2015

    Background: Pomegranate (Punica granatum L.) is commonly consumed as fresh fruit and fruit juice. It is also used in the production of jam, wine, food coloring agent, and flavor enhancer. Objective: The aim of this study…

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17. Article

    Simultaneous quantification of six alkaloid components from commercial stemonae radix by solid phase extraction‑high‑performance liquid chromatography coupled with evaporative light scattering detector

    Rong‑Rong Zhang, Dan‑Yi Lu, Zhen‑Ya Yang, Wen Zhao, Paul Pui‑Hay But, Pang‑Chui Shaw, Ren‑Wang Jiang, Zhi‑Guo Ma

    pp. 360–367 · DOI: 10.4103/0973-1296.153090 · 2015

    Background: Stemonae radix has been applied in traditional Chinese medicine for centuries. Alkaloids are the main active ingredient in stemonae radix, so their composition and concentration levels are directly linked to …

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18. Article

    Evaluation of extraction method on the chemical composition in Apeiba tibourbou Aubl’s extracts

    Frederico Severino Martins, Edemilson Cardoso da Conceição

    pp. 368–373 · DOI: 10.4103/0973-1296.153091 · 2015

    Background: The extraction method of bioactive compounds is an important step in the manufacturing of herbal medicines, because secondary metabolites with therapeutic potential are usually found in small quantities in pl…

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19. Article

    In vitro regeneration and Agrobacterium tumefaciens‑mediated genetic transformation in asakura‑sanshoo (Zanthoxylum piperitum (L.) DC. F. inerme Makino) an important medicinal plant

    Xiaofang Zeng, Degang Zhao

    pp. 374–380 · DOI: 10.4103/0973-1296.153092 · 2015

    Context: Asakura‑sanshoo (Zanthoxylum piperitum [L.] DC. f. inerme Makino) is an important medicinal plant in East Asia. Transgenic technique could be applied to improve plant traits and analyze gene function. However, t…

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20. Article

    Effects of Valerianae Radix et Rhizoma extract on psychological stress in mice

    Jeong Suk Kim, Jeong Deok Ahn, Su-In Cho

    pp. 381–388 · DOI: 10.4103/0973-1296.153093 · 2015

    Background: The aim of this study was to identify the effects of Valerianae Radix et Rhizoma water extract (VRe) originated from Valeriana fauriei Briquet on reducing psychological stress (PS) on mice. Objective: Mice we…

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