Table of Contents

Original Article

1. Article

   S1 Identification and Quantification of the Major Constituents in Egyptian Carob Extract by Liquid Chromatography–Electrospray Ionization‑Tandem Mass Spectrometry

   Asmaa Ibrahim Owis, El‑Motaz Bellah El‑Naggar

   pp. S1–S6 · DOI: 10.4103/0973-1296.176108 · 2016

   Background: Carob ‑ Ceratonia siliqua L., commonly known as St John’s‑bread or locust bean, family Fabaceae ‑ is one of the most useful native Mediterranean trees. There is no data about the chromatography methods perfor…

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2. Article

   S7 Alteration in Memory and Electroencephalogram Waves with Sub‑acute Noise Stress in Albino Rats and Safeguarded by Scoparia dulcis

   Sundareswaran Loganathan, Sheeladevi Rathinasamy

   pp. S7–S13 · DOI: 10.4103/0973-1296.176119 · 2016

   Background: Noise stress has different effects on memory and novelty and the link between them with an electroencephalogram (EEG) has not yet been reported. Objective: To find the effect of sub‑acute noise stress on the …

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3. Article

   S21 Molecular Docking Analysis of Selected Clinacanthus nutans Constituents as Xanthine Oxidase, Nitric Oxide Synthase, Human Neutrophil Elastase, Matrix Metalloproteinase 2, Matrix Metalloproteinase 9 and Squalene Synthase Inhibitors

   Radhakrishnan Narayanaswamy, Azizul Isha, Lam Kok Wai, Intan Safinar Ismail

   pp. S21–SS6 · DOI: 10.4103/0973-1296.176111 · 2016

   Background: Clinacanthus nutans (Burm. f.) Lindau has gained popularity among Malaysians as a traditional plant for anti‑inflammatory activity. Objective: This prompted us to carry out the present study on a selected 11 …

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4. Article

   Cytotoxic Properties and Complete Nuclear Magnetic Resonance Assignment of Isolated Xanthones from the Root of Garcinia cowa Roxb.

   Fatma Sri Wahyuni, Khozirah Shaari, Johnson Stanslas, Nordin HJ Lajis, Dachriyanus Hamidi

   pp. S52–SS6 · DOI: 10.4103/0973-1296.176115 · 2016

   Objective: To isolate compounds from the roots of Garcinia cowa and to evaluated their cytotoxic activity against breast (MCF‑7), prostate (DU‑145), and lung (H‑460) cell lines. Materials and Methods: The ground air‑drie…

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5. Article

   S57 New Synthetic Pyrazine Carboxamide Derivatives as Potential Elicitors in Production of Secondary Metabolite in In vitro Cultures

   Lenka Tůmová, Jiří Tůma, Martin Doležal, Zuzana Dučaiová, Jan Kubeš

   pp. S57–S62 · DOI: 10.4103/0973-1296.176117 · 2016

   Background: Silymarin, an active polyphenolic fraction of Silybum marianum, and high flavonoid content of Fagopyrum possess various interesting biological activities. The substituted pyrazine‑2‑carboxamides were previous…

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6. Article

   S71 Hybrid analysis (barcode‑high resolution melting) for authentication of Thai herbal products, Andrographis paniculata (Burm.f.) Wall.ex Nees

   Maslin Osathanunkul, Chatmongkon Suwannapoom, Nuttaluck Khamyong, Danupol Pintakum, Santisuk Na Lamphun, Kanokporn Triwitayakorn, Kitisak Osathanunkul, Panagiotis Madesis

   pp. S71–SS5 · DOI: 10.4103/0973-1296.176112 · 2016

   Background: Andrographis paniculata Nees is a medicinal plant with multiple pharmacological properties. It has been used over many centuries as a household remedy. A. paniculata products sold on the markets are in proces…

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7. Article

   Protective Mechanisms of Thymoquinone on Methotrexate‑induced Intestinal Toxicity in Rats

   Azza A. El‑Sheikh, Mohamed A. Morsy, Azza H. Hamouda

   pp. S76–S81 · DOI: 10.4103/0973-1296.176106 · 2016

   Background: Intestinal toxicity is a serious side effect in methotrexate (MTX) chemotherapy. Objective: To investigate the mechanisms by which the anticancer drug MTX‑induced intestinal damage could be prevented by thymo…

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ORIGINAL ARTICLE

1. Article

   Steroidal Saponin Diosgenin from Dioscorea bulbifera Protects Cardiac Cells from Hypoxia-reoxygenation Injury Through Modulation of Pro-survival and Pro-death Molecules

   Karuppiah Shanmugasundarapandian Jayachandran, A. Hannah Rachel Vasanthi, Narasimman Gurusamy

   pp. S14–S20 · DOI: 10.4103/0973-1296.176114 · 2016

   Background: Diosgenin, a steroidal saponin from plants, exhibits many biological potentials. Herein, the cardioprotective role of diosgenin is studied. Materials and Methods: The effect of diosgenin, isolated from Diosco…

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2. Article

   Potential Antidepressant Constituents of Nigella sativa Seeds

   Ehab S. Elkhayat, Mohammad S. Alorainy, Ibrahim M. El-Ashmawy, Shawkat Fat’hi

   pp. S27–S31 · DOI: 10.4103/0973-1296.176118 · 2016

   Background: Nigella sativa Linn. is well known seed in the Middle East, Asia, and the Far East as a natural remedy for many ailments and as a flavoring agent proclaimed medicinal usage dating back to the ancient Egyptian…

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3. Article

   Crispene A, B, C and D, Four New Clerodane Type Furanoid Diterpenes from Tinospora crispa (L.)

   Farhad Hossen, Rubaida Ahasan, Mohammad Rashedul Haque, Bilkis Begum, Choudhury Mahmood Hasan

   pp. S37–S41 · DOI: 10.4103/0973-1296.176116 · 2016

   Background: Tinospora crispa (L.) is used to alleviate the symptoms of diabetes mellitus in folk medicine. It is also used for hypertension and to treat malaria, remedy for diarrhea, and as vermifuge. Materials and Metho…

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4. Article

   Essential Oil from the Resin of Protium heptaphyllum: Chemical Composition, Cytotoxicity, Antimicrobial Activity, and Antimutagenicity

   Ewelyne Miranda Lima, Didley Sâmia Paiva Cazelli, Fernanda Endringer Pinto, Renata Alves Mazuco, Ieda Carneiro Kalil, Dominik Lenz, Rodrigo Scherer, Tadeu Uggere Andrade, Denise Coutinho Endringer

   pp. S42–S6 · DOI: 10.4103/0973-1296.176113 · 2016

   Background: Protium heptaphyllum (Aubl.) March is popularly used as an analgesic and anti‑inflammatory agent. Objective: This study aimed to evaluate the chemical composition of P. heptaphyllum essential oil, its cytotox…

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5. Article

   Bioactivities of Ethanolic Extract and its Fractions of Cistus laurifolius L. (Cistaceae) and Salvia wiedemannii Boiss. (Lamiaceae) Species

   Osman Ustun, Berrin-Ozcelik Berrin-Ozcelik, Turhan Baykal

   pp. S82–S5 · DOI: 10.4103/0973-1296.176125 · 2016

   Background: Cistus laurifolius L. (Cistaceae) and Salvia wiedemannii Boiss. (Lamiaceae) have been used for treatment of some illnesses in Turkish folk medicine. In the present study, the ethanolic extract and its fractio…

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1. Article

   Endoplasmic reticulum stress‑induced apoptotic pathway and mitochondrial dysregulation in HeLa cells treated with dichloromethane extract of Dillenia suffruticosa

   Wan Abd Ghani Wan Nor Hafiza, Latifah Saiful Yazan, Yin Sim Tor, Jhi Biau Foo, Nurdin Armania, Heshu Sulaiman Rahman

   pp. S86–S95 · DOI: 10.4103/0973-1296.176107 · 2016

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