Table of Contents

Sachin Ranjan, Nidhi Singh Kushwaha, Shalini Trivedi, Neha Tiwari, Salman Khan

pp. 7–26 · DOI: 10.1177/09731296241243132 · 2025

Psoralea corylifolia (PC) seed extract (PCE) has been extensively utilized as an herbal drug due to its favorable effects on human health. It’s extracts and active components have demonstrated a variety of biological act…

Mohammed Abu Sayeed, Min Gab Kim

pp. 27–43 · DOI: 10.1177/09731296241262567 · 2025

A naturally occurring xanthone, mangostanin (1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9- one), was isolated from Garcinia mangostana L. It demonstrates a range of pharmacological effects, such…

Mohd Saeed, Ambreen Shoaib, Lubna Azmi, Asma Al-Shammary, Md Jahoor Alam, Yazeed Albulaihed, Vishal M Balaramnavar, Chandrakant Bonde, Mohd Adnan Kausar, Abdelmuhsin Abdelgadir, Saad Saeed Alqathani, Irfan Ahmad Ansari

pp. 44–54 · DOI: 10.1177/09731296241274877 · 2025

Background: It is estimated that the plant has been utilized in India’s traditional medical system for close to 2,500 years. Alkanin is a key active component in Boraginaceae medicinal plant roots. Many scientists are in…

Xie Ran, Liu Feng, Fang Hongying, Xu Yuguo, Zhang Honglian

pp. 55–59 · DOI: 10.1177/09731296241265167 · 2025

Background: Lonicerae japonicae flos, a representative kind of Traditional Chinese Medicine (TCM) for clearing heat and detoxifying, is known as Jinyinhua in China. The determination of multiple components’ content, espe…

Qishan Sun, Xiaodong Zhan, Feng Jiang

pp. 60–66 · DOI: 10.1177/09731296241281445 · 2025

Background: Cell division control protein 42 homolog (Cdc42)/neuronal Wiskott–Aldrich Syndrome Protein (N-WASP) is involved in a variety of tumors; however, its regulatory mechanism in breast cancer is unclear. Objective…

Sasi Kumar Murugan, Bharathi Bethapudi, Deepak Mundkinajeddu

pp. 67–73 · DOI: 10.1177/09731296241281434 · 2025

Background: The immune system plays a crucial role in protecting the host by regulating biological activities in multiple organs and circulatory fluids. The phytoextracts are evident to modulate a series of biological ac…

Xing Jin, Chunhui Ma, Xiaojing Tan, Jian Qian, Yongbing Chen, Dongfeng Wang

pp. 74–80 · DOI: 10.1177/09731296241262832 · 2025

Background and Purpose: Cantharidin can or cannot reverse the drug resistance of non-small cell lung cancer to cisplatin (DDP) by reducing the expression of programmed cell death ligand 1 (PD-L1). Materials and Methods: …

Lan Li, Lina Yin, Jia Shi, Li Zheng, Liu Min, Xiaoling Wu

pp. 81–88 · DOI: 10.1177/09731296241282390 · 2025

Background: Although it does not represent a threat to healthy humans, Pseudomonas aeruginosa is a type of aerobic, gramnegative bacteria that can cause catastrophic infections in patients with immune system abnormalitie…

Mi-Rae Shin, Jeong Won Choi, Seong-Soo Roh

pp. 89–98 · DOI: 10.1177/09731296241262566 · 2025

Background: Hepatocellular carcinoma (HCC) is one of the most common malignancies and a leading cause of cancerrelated mortality and morbidity worldwide. Objectives: This study evaluated the enhanced efficacy of a combin…

Qi Li, Yong Zhou, Hai-Feng Yang, Guang-Hong Yu, Xiao-Hui Chi

pp. 99–106 · DOI: 10.1177/09731296241264616 · 2025

Background: Poor sleep quality and even insomnia are global problems, especially after the COVID-19 pandemic, and bioactive substances in natural herbal medicines may improve subjective sleep for people with insomnia. Ho…

Rewaida Abdel-Gaber, Esam M. Al-Shaebi, Tahani Al-Otaibi, Esam S. Al-Malki, Nawal Al-Hoshani, Saleh Al Quraishy

pp. 107–115 · DOI: 10.1177/09731296241264060 · 2025

Background: Eimeria papillata is a parasitic protozoan that causes intestinal coccidiosis in mice. Due to the rise of drugresistant strains, medicinal plants are now employed to treat parasite diseases. Objectives: This …

Hui Dong, Jie Song, Yanju Jia, Hongyan Cui, Xu Chen

pp. 116–123 · DOI: 10.1177/09731296241277301 · 2025

Background: Preeclampsia is a pregnancy complication characterized by high blood pressure and signs of damage to another organ system, often the kidneys. Recent studies suggest that endothelial dysfunction and trophoblas…

Yanxin Dang, Wenjie Zhao, Xiaohan Li, Yongchao Chen, Jie Liu, Lin Li, Minzhen Xie, Zhouxiu Chen, Siqi Gu, Qi Wang, Guijun Liu

pp. 124–132 · DOI: 10.1177/09731296241280347 · 2025

Background: Potentilla discolor Bunge (PDB) is a plant of the Rosaceae family. A wide range of pharmacological activities, such as antibacterial, hypoglycemic, and others, can be achieved through its chemical components,…

Qijie Mei, Wenfei Xu, Qi Hu, Jinrong Guo, Chao Zeng, Chunyu Ming, Chongming Li, Changshen Yuan, Kan Duan

pp. 133–141 · DOI: 10.1177/09731296241283126 · 2025

Background: Osteoarthritis (OA) is a chronic disease worldwide. With resatovir usually used as an inhibitor, resatovir and glycyrrhizic acid have several pharmacological activities. Objectives: We intend to explore the m…

You Jeong Jin, Su Jin Lee, Ji Eun Kim, Yu Jeong Roh, Hee Jin Song, Ayun Seol, Tae Ryeol Kim, Kyeong Seon Min, Eun Seo Park, Gi Ho Park, Hye Mi Kang, Nam Jun Kang, Ki Won Lee, Young-Whan Choi, Dae Youn Hwang

pp. 142–151 · DOI: 10.1177/09731296241266394 · 2025

Background and Purpose: The anti-obesity effects of vitalmelon extracts have been well verified in only adipogenesis and lipogenesis of adipocytes and high-fat diet-induced obesity mice except lipolysis. Therefore, we we…

Mi Zhang, Yuntian Zhang, Hongyun Wang, Chunlei Fan

pp. 152–160 · DOI: 10.1177/09731296241281441 · 2025

Background: Hyperlipidemia, caused by abnormal lipid metabolism, has become a significant health concern, especially in younger populations. While statins are commonly used for treatment, they often cause severe side eff…

Kuo Liu, Nannan Ding, Mengying Han, Shuping Shen, Lin Li, Fang Bian, Li Chen, Ji Zhang, Lailiang Qu, Dan Yang

pp. 161–169 · DOI: 10.1177/09731296241279103 · 2025

Background: Neurodegenerative diseases (NDs) have become a significant public health problem, and oxidative stress (OS) serves as a pivotal factor in the pathological progression of NDs. Pharmacological research indicate…

Yuxi Jia

pp. 170–180 · DOI: 10.1177/09731296241281421 · 2025

Background: Diabetic retinopathy (DR) is a major cause of visual problems and ultimately results in vision loss. Nearly 25% of diabetic patients have suffered from DR. Objectives: The present research has been designed t…

Doha M. Al-Nouri, Ghalia Shamlan, Latifah Y. Al-Faifi, Wahidah H. Al-Qahtani, Ghedeir M. Alshammari, Islam A. El Redh, Shaista Arzoo

pp. 181–191 · DOI: 10.1177/09731296241262555 · 2025

Background: Rheumatoid arthritis (RA) is a chronic, immune-inflammatory disease that could be managed by an attenuation in dietary habits. With the increase in research that links the effect of nutrition linked to RA. Ob…

Xia Lei, Si-Cheng Yang, Kang-Bo Peng, Meng-Fan Wang, He-Zhen Wu, Yan-Fang Yang

pp. 192–206 · DOI: 10.1177/09731296231220980 · 2025

Objectives: The objective of this study was to investigate the impacts and mechanisms of Picroside II on hepatocellular carcinoma (HCC). Materials and Methods: The GeneCards database was mined for HCC-related targets. Th…