Table of Contents

Original Article(continued)

1. Article

   Anticancer Effects of Piper nigrum Extract against Cholangiocarcinoma Cells

   Benjaporn Buranrat, Laddawan Senggunprai, Auemduan Prawan, Veerapol Kukongviriyapan

   pp. 160–167 · DOI: 10.4103/pm.pm_521_21 · 2022

   Objectives: Piper nigrum (PN) is well known for its cytotoxic and pharmacological benefits in several cancer cells. However, there is less documented evidence about its cytotoxic efficacy against cholangiocarcinoma (CCA)…

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2. Article

   Syringin Protects against Cerebral Ischemia and Reperfusion Injury via Suppression of Inflammatory Mediators and Toll‑Like Receptor/MyD88 Signaling Pathway in Rats

   Yihong Huang, Xiaopeng Wang, Shaobing Guan, Han Lin, Zhizhong Mei, Zhi Huang

   pp. 168–174 · DOI: 10.4103/pm.pm_98_21 · 2022

   Objectives: In this research work, we envisioned to observe the neuroprotective actions of syringin against ischemic‑reperfusion (I/R)‑provoked ischemic stroke in rats. Materials and Methods: The focal cerebral I/R injur…

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3. Article

   Network Pharmacology Analysis with Molecular Docking of Phytochemicals of Panax ginseng against Osteosarcoma

   Fahad Hassan Shah, Song Ja Kim

   pp. 175–182 · DOI: 10.4103/pm.pm_518_21 · 2022

   Background: Panax ginseng is a perennial medicinal herb also known as Korean ginseng or Insam (인삼), commonly found in Korean Peninsula. These herbs are used to treat different types of diseases. Recent studies have shown…

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4. Article

   Protective Effect of the Traditional Korean Herbal Prescription, Bojangunbi‑tang, on Non-steroidal Anti‑Inflammatory Drug‑induced Small Bowel Injury

   Minji Cho, Jinhyun Bae, Ji‑Hye Park, Youngmin Bu, Beom‑Joon Lee, Jae‑Woo Park, Jinsung Kim, Hye Hyun Yoo

   pp. 183–187 · DOI: 10.4103/pm.pm_333_21 · 2022

   Background: Bojanggunbi‑tang (BGT) is a well‑known combination of ancient Korean herbal medicines and has been widely used for treating gastrointestinal symptoms. Objectives: This study was aimed at investigating whether…

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5. Article

   Anti‑Inflammatory, Antioxidant, Cytotoxic Activities, and Sesquiterpenoid Contents of Paralemnalia thyrsoides

   Aya Ali Alassass, Marwa S. Abubakr, Walied M. Alarif, Seif-Eldin N. Ayyad, Abd-Elsalam E. Mohammed

   pp. 188–192 · DOI: 10.4103/pm.pm_222_21 · 2022

   Objectives: Paralemnalia thyrsoides is an octocoral species of the family Nephtheidae. It has established as platform for the production of a varied array of sesquiterpenoids such as africanane, nardosinane, and neolemna…

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6. Article

   Elucidating the Immunomodulatory Effect of Daidzein in Benzo(a)pyrene ‑Induced Lung Cancer Mice Model through Modulation of Proliferating Cell Nuclear Antigen, NF‑κB, CYP1A1, and NRF

   Jianyu Feng, Wei Meng, Yandong Liu, Cuiyun Li, Chunnan Zhang, Peng Wang, Hesham S. Almoallim, Velu Manikandan, Hui Guan

   pp. 193–200 · DOI: 10.4103/pm.pm_325_21 · 2022

   Objectives: In this study, we aimed to understand the immunomodulatory activity of DAZ in the mice model with benzo(a)pyrene (B(a)P)‑induced lung carcinoma. Materials and Methods: The mice were divided into five groups: …

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7. Article

   The Ethanol Extract of Caragana sinica Ameliorated Skin Lesions in Mice with Contact Dermatitis

   Seonkyung Jang, Yoonhyoung Kang, Yuntae Kang, Seungyeop Oh, Soyeon Kim, Ji‑Hyo Lyu, Hyungwoo Kim

   pp. 201–206 · DOI: 10.4103/pm.pm_370_21 · 2022

   : Background: Caragana sinica (Buc’hoz) Rehd, which belongs to the legume family, is used to treat a variety of diseases such as gout, high blood pressure, neuralgia, arthritis, and eczema. Morden studies reveal that C. …

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8. Article

   Genetic Clonal Fidelity Assessment of Rhizome‑Derived Micropropagated Acorus calamus L. – A Medicinally Important Plant by Random Amplified Polymorphic DNA and Inter‑Simple Sequence Repeat Markers

   Leimapokpam Tikendra, Oinam Sushma, Thoungamba Amom, Nandeibam Apana Devi, Sonia Paonam, Nongthombam Bidyananda, Angamba Meetei Potshangbam, Abhijit Dey, Rajkumari Sanayaima Devi, Potshangbam Nongdam

   pp. 207–215 · DOI: 10.4103/pm.pm_408_21 · 2022

   Objectives: Development of fast and reliable in vitro regeneration protocol for A. calamus and clonal fidelity assessment of the regenerants using molecular markers. Materials and Methods: Plants were regenerated on Mura…

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9. Article

   Synthesis, Characterization, and Anti‑hepatocellular Carcinoma Effect of Glycyrrhizin‑coupled Bovine Serum Albumin‑loaded Luteolin Nanoparticles

   Yongxia Yang, Huaguo Liang, Pei Zeng, Wei Fu, Jingwei Yu, Luxi Chen, Dong Chai, Ying Wen, Ali Chen, Yongli Zhang

   pp. 216–225 · DOI: 10.4103/pm.pm_34_21 · 2022

   Objectives: Synthesis of glycyrrhizin‑coupled bovine serum albumin‑loaded Lut nanoparticles (GL‑BSA‑Lut‑Nps) to progress the water solubility, anticancer effect, liver targeting, cycle arrest, induction apoptosis, and re…

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10. Article

    Anti‑tick Potential and Intra‑Specific Chemical Variations in Ageratum conyzoides L. Collected from Indus Plain and Central India

    Bhanu Kumar, Pushpendra Kumar Shukla, Anil Kumar Sharma, Ajay Kumar Singh Rawat, Yashwant Singh Rawat, Srikant Ghosh, Sharad Srivastava

    pp. 226–232 · DOI: 10.4103/pm.pm_261_21 · 2022

    Objectives: Search for safe and efficacious plant‑based alternatives to the chemical acaricides and to assess chemical variability among intra‑specific germplasms. Materials and Methods: Ageratum conyzoides L. samples we…

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11. Article

    Enhanced Synergistic Antitumor Efficacy with Topotecan (Camptothecin Derivative) and Curcumin Analogs Coadministration in Novel Proniosomal Formulations

    Afzal Haq Asif, Predeepkumar Narayanappa Shiroorkar, Purna Singh, Pottathil Shinu, Nagaraja Sreeharsha, Md. Khalid Anwer

    pp. 233–241 · DOI: 10.4103/pm.pm_588_21 · 2022

    Background: In the modern era of therapeutics, the proniosomal system has been identified as the most intriguing one among various novel systems, thus considerably enhancing the bioavailability of low‑soluble drugs. The …

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12. Article

    Possible Correction of Thiazide‑Induced Hypokalemia with Co‑Administration of Date Palm Fruits with Hydrochlorothiazide in Rats

    Promise Madu Emeka, Kazeem Yusuff Babatunde, Mahesh Attimarad, Abdulaziz K. Al Mouslem

    pp. 242–246 · DOI: 10.4103/pm.pm_548_21 · 2022

    Background: Thiazide diuretics are one of the most effective, least expensive antihypertensive medicines, however, they are associated with hypokalemia, which can complicate the outcome of care among hypertensive patient…

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