Volume 57, Issue 3S

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1. Article

   Formulation and Evaluation of Nanoemulsion of the Phenolic Content of Foeniculum vulgare for Antidepressant and Antihypertensive Potentiality

   Sanjita Das, Sweta Rani

   pp. s660–s666 · DOI: 10.5530/ijper.57.3s.75 · 2023

   Objectives: Foeniculum vulgare (common name: fennel; family: Umbelifereae) is a well-documented plant with various medicinal properties to manage different types of disease. Depression and hypertension are associated wit…

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2. Article

   Bioactivity-guided Isolation of Phytoconstituents from Saraca asoca Seeds for Anti-asthmatic Potential

   Chandrakant Prabhu Rathod, Mahavir Ghante

   pp. s667–s677 · DOI: 10.5530/ijper.57.3s.76 · 2023

   Objectives: It is interesting to consider biologically active substances derived from natural sources as potential novel medications for infectious disorders. Saraca asoca is an indigenous medicinal plant with lots of tr…

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3. Article

   Ethnobotanical Study of Medicinal Plants Used Traditionally for Managing Cuts and Wounds by the Rural People of Kailashpur, Assam, India

   Pal Gogoi, Saikat Sen

   pp. s678–s689 · DOI: 10.5530/ijper.57.3s.77 · 2023

   Background: Folk medicinal knowledge of plants is vital in primary health care management system, predominantly in rural and remote areas. Managing cuts and wounds continues to be a significant healthcare issue. Material…

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4. Article

   Syringodium isoetifolium Fosters an Antioxidant Defense System, Modulates Glycolytic Enzymes and Protects Membrane Integrity in DEN-induced Hepatocellular Carcinoma in Albino Wistar Rats

   Dhanaraju Kavitha, Ramakrishnan Padmini, Magharla Dasaratha Dhanaraju, Chandravadivelu Gopi, Deepan Thiyagarajan, Alekkhya Veeramaneni

   pp. s690–s700 · DOI: 10.5530/ijper.57.3s.78 · 2023

   Background: Syringodium isoetifolium seagrass has bioactive constituents with potential pharmacological uses, but their use is limited. Materials and methods: Wistar albino rats were split into five groups. Except for gr…

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5. Article

   Brassinin Exhibits Anti-Diabetic Activity against Streptozotocin-induced Diabetes Mellitus in Experimental Rats

   Bixia Xu, Abdullah A. Alarfaj, Abdurahman Hajinur Hirad, Nandakumar Natarajan, Petchi Iyappan, Samer Hasan Hussein Al Ali

   pp. s701–s709 · DOI: 10.5530/ijper.57.3s.79 · 2023

   Background: Diabetes mellitus is among the most serious public health problems worldwide. Materials and Methods: 35mg/kg STZ was injected to rats for stimulating diabetes. Then rats were treated with 25mg/kg of brassinin…

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6. Article

   In vitro and in vivo Antidiabetic Activity of Ag Nanoparticles Mediated from Gymnemic Acid I and II

   Navanita Sivaramakumar, Kalakotla Shanker

   pp. s710–s717 · DOI: 10.5530/ijper.57.3s.80 · 2023

   Background: Gymnema sylvestre is traditionally used to treat diabetes in Asia. Materials and methods: GA-I and GA-II were docked to PTP 1B. Nanoparticles were produced using centrifugation green synthesis. Results: Blood…

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7. Article

   Evaluation of Anti-obesity Activity of n-hexane and Methanolic Extracts of Cajanus cajan Linn. Seeds Using Enzymatic Methods

   Sakshi Sharma, Anjna Rani

   pp. s718–s723 · DOI: 10.5530/ijper.57.3s.81 · 2023

   Objectives: To evaluate the in vitro anti-obesity activity of Cajanus cajan Linn. seeds. Materials and Methods: Phytochemical screening and in vitro studies on pancreatic lipase and alpha-glucosidase activity were perfor…

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8. Article

   Isolation and Functioning Investigation of Salvia hispanica Seed Mucilage as a Potential Sustained Release Carrier for Water Soluble Drug

   Dibya Sundar Panda, Madhusmruti Khandai

   pp. s724–s733 · DOI: 10.5530/ijper.57.3s.82 · 2023

   Background: Natural biopolymers or hydrogels are explored to sustain release of water-soluble drugs. Materials and Methods: Mucilage was isolated from Salvia hispanica seeds. Gelispheres loaded with Losartan Potassium (L…

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9. Article

   The Formation Analysis of Ca (II), Mg (II), Zn (II) and 5-Hydroxysalicylic Acid Binary Complexes in Cetyltrimethylammonium Bromide Cationic Micelles

   Malla Ramanaiah, Sattaru Gouthamsri

   pp. s734–s741 · DOI: 10.5530/ijper.57.3s.83 · 2023

   Aim: The aim of the study is to confirm the species formed and validate models by statistical treatment. Materials and Methods: Alkali metric titrations were carried out in CTAB-water mixtures using sodium hydroxide. Res…

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10. Article

    Multicomponent Synthesis, Characterization of Novel Pyrimidine Derivatives with Anti-cancer Potential

    Swetha Devidi, M Swamivel Manickam, R Suresh

    pp. s742–s748 · DOI: 10.5530/ijper.57.3s.84 · 2023

    Background: Design and development of target specific anti-cancer agents is a central research goal. Materials and Methods: Substituted pyrimidines were synthesized from substituted enamine, triethoxy methane and ammoniu…

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11. Article

    Synthesis of Cyclopyrrolidine Clubbed with Oxadiazole Bases and Evaluation of their Anti-Diabetic Activity through in vivo Model

    Megha Tukaram Salve, Shailaja Jadhav

    pp. s749–s757 · 2023

    Background and Aim: Based on inhibitors of DPP-IV, there is a fantastic method for creating anti-diabetic medications. These inhibitors regulate diabetic patients' blood sugar levels to prevent difficulties with their he…

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12. Article

    Understanding the Trending of Laboratory Investigations as Part of Quality Management Systems-A Quality Assurance Perspective

    Anupriya Naduparambil Reji, Marina Koland, Sandeep Divate Satyanarayana

    pp. s758–s765 · 2023

    Background: In the pharmaceutical sector, the effectiveness of the laboratory and its compliance with regulatory standards is critical in establishing an effective Quality Management System (QMS). Objectives: The present…

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13. Article

    Stability Indicating Reverse Phase-High Performance Liquid Chromatography Method for Simultaneous Estimation of Cabotegravir and Rilpivirine

    Padmabhushana Chary Vemuluri, Sireesha Dodda

    pp. s766–s771 · 2023

    Background: For the estimation of cabotegravir and rilpivirine in the bulk and pharmaceutical dosage form, a stability-indicating reverse-phase high-performance liquid chromatography method was developed and validated us…

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14. Article

    Marker Based Standardization of Quercetin in Marketed Capsules by Novel Zero Order Spectroscopic and Area Under Curve Spectroscopic Methods

    Revati R. Surve, Harshal P. Tavanoji, Taufeeque R. Nadaf, Shweta C. Pote, Meenaxi M. Maste, Shailendra S. Suryawanshi

    pp. s772–s786 · 2023

    Background: Quality control and standardization of phytomedicines play a vital role in herbal drug industries. Marker based quantification and standardization is one of the essential approaches used in quality evaluation…

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15. Article

    Different Innovative UV-spectroscopic Approaches for Simultaneous Assessment of Celecoxib and Tramadol Hydrochloride in Binary Mixture

    Ashim Kumar Sen, Preksha Darji, Dhanya B. Sen, Aarti S. Zanwar, Chintan J. Aundhia, Rajesh A. Maheshwari

    pp. s787–s797 · 2023

    Background and Aim: Tablets containing celecoxib and tramadol hydrochloride that are sold under the brand name Seglentis® have given approval by the “Food and Drug Administration” (FDA) for the treatment of adults suffer…

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16. Article

    Stability-Indicating Reversed Phase-HPLC Method Development and Validation for Estimation of Phenylephrine in Bulk and Tablet

    Shruti Srivastava, Suneela Dhaneshwar, Neha Kawathekar

    pp. s798–s804 · 2023

    Background: This study is aimed to develop a validated stability-indicating method of a nasal decongestant phenylephrine hydrochloride in bulk and tablet. Materials and Methods: A sensitive, accurate, and specific revers…

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17. Article

    Implementation of Analytical Quality by Design Methodology to Develop a UV-spectrometric Technique for Arteether Quantification

    Neha Bajwa, Pallavi Saroch, Ashish Baldi

    pp. s805–s813 · 2023

    Aim/Background: Analytical Quality by Design refers to applying the Quality by Design idea to the development of analytical procedures. The present study emphasizes the AQbD concept of developing and validating a spectro…

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18. Article

    Chemical Composition and Therapeutic Effects of Ammodicus leucotricus Essential Oils on Neurobehavioral Changes in Wistar Rats after Experimental Scorpion Envenomation

    Ammam Abdelkader, Belmamoun Ahmed Reda, Chadli Redouane, Boudia Rafik, Benhafsa Mekhalef Fouad, Hafidh Zemour, Didier Villemin, Walid Soufan, Fathi Abdellatif Belhouadjeb

    pp. s814–s820 · 2023

    Background: Our study consists of a study of the chemical composition of the essential oil administered to a batch of rats undergoing a scorpion sting. Compared with control batches, the nervous state was evaluated by se…

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19. Article

    Effects of Artemisinin on Anti-epileptogenic, Antioxidant and Cholinesterase Enzymes in Pentylenetetrazole-induced Kindling Model in Mice

    Yilmaz Kocak, Oruc Yunusoglu, Zubeyir Huyut, Fikret Turkan

    pp. s821–s830 · 2023

    Background: Artemisinin (ART) is a compound synthesized from the plant Artemisia annua. This compound has various therapeutic effects and is widely used against malaria. However, ART is known to have modulating effects o…

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