Table of Contents

Fenglin Li, Yumiao Ma, Wuyang Hua, Yanxia Liu, Li Li, Zhongkui Lu, Xiaokun Jiang, Chao Liu, Jingxue Liu

pp. 669–674 · DOI: 10.4103/pm.pm_585_21 · 2022

Background: Despite tremendous efforts that have been made, cancer is still the leading cause of death all over the world. Chemotherapy, considered a routine method, always faces severe side effects and drug resistance. …

Chao‑Wen Hsueh, Chun Chen, Po‑Yen Chiu, Ni‑Na Chiang, Chi‑Cheng Lu, Jai‑Sing Yang, Fu‑An Chen

pp. 675–678 · DOI: 10.4103/pm.pm_101_22 · 2022

Background: Benzyl isothiocyanate (BITC) is a natural compound found in numerous cruciferous vegetables, and research has indicated that it has diverse biological activities. Isothiocyanate and its derivatives are the ma…

Xi Mei, Conglong Qiu, Lingli Shi, Xingxing Li, Mengxiang Yang, Jun Hu, Zhongming Chen, Chenjun Zou

pp. 679–684 · DOI: 10.4103/pm.pm_490_21 · 2022

Background: Curcumin possesses multifunctional pharmacological properties, including antioxidant, anti‑inflammatory, and antidiabetic properties. We investigated whether curcumin can improve pathological changes associate…

Zhengfeng Fu, Nian Sun, Shuqi Li, Jiahong Han, Shiyue Lang, Xiuyong Yue, Enbo Cai

pp. 685–691 · DOI: 10.4103/pm.pm_451_21 · 2022

Background: 20(R)‑ginsenoside Rg3 (R‑Rg3) is a kind of ginseng glycol tetracyclic triterpenoid saponin, which is a recognized traditional Chinese medicine monomer and has the action of inhibiting the proliferation of tum…

Yonghong-Liang Yonghong-Liang, Xiuying-Huang Xiuying-Huang, Xunli-Xia Xunli-Xia, Huiying-Yao Huiying-Yao, Yu-Lu Yu-Lu

pp. 692–698 · DOI: 10.4103/pm.pm_6_22 · 2022

Objectives: To investigate the effects of gavage and transdermal administration on the anti‑tumor activity of QJ623 (extracts of Paris polyphylla rhizome and Tinosporae Radix) on a murine H22 solid tumor transplantation …

Dae‑Young Noh, Ji‑Yeon Hyun, Donguk Kim, Dong‑Seok Lee

pp. 699–706 · DOI: 10.4103/pm.pm_497_21 · 2022

Background: Orostachys japonicus has traditionally been used for antifever, anti‑inflammation, and anticancer. O. japonicus has not yet been studied for cosmetic effects. Objectives: In this study, O. japonicus extracts …

Miao Yu, Huibo Guan, Yanyan Zhou, Xinmin Yao, Yuguang Yang

pp. 707–712 · DOI: 10.4103/pm.pm_202_21 · 2022

Objectives: The present study evaluated Ruta graveolens Linn. extract (RGLE) for its possible role in the treatment of vascular dementia (VD) in the rat model and inhibition of autophagy in hippocampus tissues. Materials…

Zhiling Zhuang, Shenghong Wu, Shimin Deng, Pengjian Zhu, Xin Zhou, Xiaoying Chen, Weimin Zhang, Xiaoxia Gao

pp. 713–728 · DOI: 10.4103/pm.pm_340_21 · 2022

Background: Agarwood is a resinous heartwood produced in certain Aquilaria species that is often used as a spice and Chinese medicine materials. Objectives: This study aimed to comprehensively evaluate the agarwood quali…

Laddawan Senggunprai, Auemduan Prawan, Sarinya Kongpetch, Veerapol Kukongviriyapan, Benjaporn Buranrat

pp. 729–737 · DOI: 10.4103/pm.pm_133_22 · 2022

Background: Cholangiocarcinoma (CCA), epithelial bile duct cancer, is deadly cancer with a very poor prognosis and standard anticancer drugs strategy remains poor and unfavorable outcomes. Objectives: In this study, we e…

Zhihong Zhang, Yuanning Zeng, Donghui Peng, Na Xing, Haodong Bai, Yuxin Li, Na Cui, Huilin Su, Tingting Qiao, Congjing Shi, Haixue Kuang, Qiuhong Wang

pp. 738–745 · DOI: 10.4103/pm.pm_14_22 · 2022

Background: We investigated the composition and structure of intracellular polysaccharides in cucumber seeds (CSs) and their effect on Sprague-Dawley (SD) rats and potential activity for fracture healing. Materials and M…

Haifeng Zhu, Qian Xia, Hong Jiang, Furong Wang, Long Yu, Liwei Zhang

pp. 746–751 · DOI: 10.4103/pm.pm_535_21 · 2022

Background: Thrombosis is a major complication and is responsible for cardiovascular diseases (CVDs). The majority of CVDs like stroke, coronary syndrome, and vascular ailments are tightly connected to venous/arterial bl…

Wei‑xia Li, Xiao‑yan Wang, Hui Zhang, Ming‑liang Zhang, Ya‑li Wu, Lu Niu, Shu‑qi Zhang, Xiao‑fei Chen, Jin‑fa Tang

pp. 758–765 · DOI: 10.4103/pm.pm_332_21 · 2022

Background: Psoralea Fructus (PF) is one of the most frequently applied tonic Chinese herbs with various bioactivities, while recently, the idiosyncratic drug‑induced liver injury (IDILI) nature of PF was addressed, and …

Hao Huiyao, Zhang Rongjin, Guo Pengpeng, Zhang Fang, Xu Yi, Li Chunhui, Hao Yongmei

pp. 766–772 · DOI: 10.4103/pm.pm_454_21 · 2022

Background: The genus <em>Crotalaria</em> (Fabaceae) is known for its diverse pharmacological activities. <em>Crotalaria pallida</em> Aiton is a medicinal plant used in traditional medicine for various ailments. Objectiv…

Mejdi Snoussi, Iqrar Ahmad, Harun Patel, Emira Noumi, Rafat Zrieq, Mohd Saeed, Shadi Sulaiman, Nasrin E. Khalifa, Fakher Chabchoub, Vincenzo De Feo, Mohamed A. M. Gad-Elkareem, Kaïss Aouadi, Adel Kadri

pp. 773–782 · DOI: 10.4103/pm.pm_251_22 · 2022

Background: Tabebuia impetiginosa is an important medicinal plant rich in lapachol, α‑lapachone, and β‑lapachone known to possess several biological activities. Objective: In this study, we investigated the drug potentia…

Jin A. Lee, Min Ju Kim, Mi-Rae Shin, Hae-Jin Park, Seong-Soo Roh

pp. 783–789 · DOI: 10.4103/pm.pm_422_20 · 2022

Background: Angelica gigas Nakai (AGN) is well‑known for anti‑ inflammatory and anti‑oxidative effects; however, the mechanism underlying the protective effects of AGN on monosodium iodoacetate (MIA)‑induced osteoarthrit…

Weizhuo Lu, Jingru Tong, Miaomiao Zhou, Jiyue Wen

pp. 752–7 · DOI: 10.4103/pm.pm_572_21 · 2022

Objective: The aim of this study was to demonstrate the role of the total flavones of Abelmoschus manihot (TFA) in the reactive proliferation of astrocytes after cerebral ischemia in mice. Materials and Methods: The expr…