Table of Contents

Original Article(continued)

1. Article

   Protective Effect of Caffeic Acid Phenethyl Ester against Acute and Subchronic Mice Cardiotoxicity Induced by Cyclophosphamide Alone or Plus Naproxen

   Promise Madu Emeka, Mohamed A. Morsy, Ibrahim A. Alhaider, Muhammad S. Chohan

   pp. 585–591 · DOI: 10.4103/pm.pm_159_20 · 2020

   Objectives: This study aims to investigate the possible protective effect of caffeic acid phenethyl ester (CAPE) in the co‑administration of CYP and naproxen (NAP) with acute and subchronic treatments in mice. Materials …

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2. Article

   Profiling of Antiviral and Antioxidant Phytochemicals of Pterocephalus frutescens Hochist. using High‑Resolution Ultra‑Performance Liquid Chromatography/Quadrupole Time‑of‑Flight Mass Spectrometer

   Atef A. El-Hela, Mostafa M. Hegazy, Marwa S. Abu Bakr, Hatem S. Abbass

   pp. 592–599 · DOI: 10.4103/pm.pm_558_19 · 2020

   Background: Medicinal plant extracts and herbal preparations are complex mixtures of active and ballast substances, which may contain in frequently up to several hundreds of different constituents, with no exactly define…

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3. Article

   Polygonum chinense Water Decoction Lessens Acute Lung Injury in Mice Induced by Influenza Virus

   Rongkui Liu, Zhao Zhang, Xueyang Peng, Yueling Su, Yan Xiao, Xiuli Ji

   pp. 600–604 · DOI: 10.4103/pm.pm_206_19 · 2020

   Background: In traditional Chinese medicine, Polygonum chinense has been used to treat influenza. However, little information is available from current studies regarding the anti‑influenza pharmacological activities of P…

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4. Article

   Fisetin Attenuates Gastric Mucosal Lesions through Modulating Nuclear Factor‑Kappa B and Peroxisome Proliferator‑Activated Receptor‑γ in Rats

   Jinchen Hu, Li Cai, Zengwu Yao, Zhenbin Zhang, Menglai Zhang, Yifei Zhang, Lixin Jiang, Baohong Hu

   pp. 605–612 · DOI: 10.4103/pm.pm_4_20 · 2020

   Objective: The objective of this study was to explore the underlying mechanism of action of fisetin on ethanol‑induced gastric ulcer model. Materials and Methods: In this study, gastric mucosal lesions were induced by et…

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5. Article

   Rehmannia radix Extract Ameliorates Imiquimod‑Induced Psoriasis‑Like Skin Inflammation in a Mouse Model via the Janus‑Kinase Signal Transducer and Activator of Transcription Pathway

   Haixiu Zhang, Minyan Dang, Xuemei Chen, Xin Yan

   pp. 613–619 · DOI: 10.4103/pm.pm_218_19 · 2020

   Background: Rehmannia glutinosa, commonly known as Dihuang, is a medicinal herb widely used in the formulations of traditional Chinese medicine. Radix or the root of Rehmannia is a vital ingredient used in various orient…

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6. Article

   Naringenin Reduced Migration in Osteosarcoma Cells through Downregulation of Matrix Metalloproteinase‑2 and Matrix Metalloproteinase‑9 and Snail

   Yuh‑Ming Chang, Ming‑Cheng Lin, Ling‑Zong Hong, Pei‑Ni Chen, Yu‑Hsin Tsai, You‑Cheng Hseu, Ke‑Min Chen, Li‑Sung Hsu, Ting‑Hsien Kao

   pp. 620–624 · DOI: 10.4103/pm.pm_31_20 · 2020

   Objectives: In this study, we investigate the effects of naringenin on osteosarcoma. Materials and Methods: 3‑(4,5‑dimethylthiazol‑2‑yl)‑2,5‑diphenyltetra zolium bromide (MTT) assay was performed to detect the cell viabi…

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7. Article

   A Special Aromatic Chrysanthemum Breed with High Content of Thujone

   Ying Zhang, Risheng Cheng, Zijie Xu, Yaoyao She, Keli Chen, Yimei Liu

   pp. 625–629 · DOI: 10.4103/pm.pm_382_19 · 2020

   Objective: The objective of the study was to determine taxonomic status of the cultivar in genus Dendranthema. Materials and Methods: The differences of morphological characteristics and volatile oil components between t…

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8. Article

   Effect and Mechanism of Ginsenoside Rg1 on Synaptic Plasticity of Oxygen‑Glucose Deprivation/Reoxygenation‑Induced Neuronal Injury

   Chen Yan, Yan Ma, Lin Li, Meng Zhang, Junhua Zhan, Xiang Fan

   pp. 630–636 · DOI: 10.4103/pm.pm_541_19 · 2020

   Objective: In this study, we aim to establish the model of oxygen–glucose deprivation/reoxygenation (OGD/ R)‑injured primary cortical neurons to mimic ischemia/reperfusion injury and investigate the mechanisms of action …

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9. Article

   Sagittaria sagittifolia Polysaccharide, a Chinese Herbal Extract, Protects against Isoniazid‑ and Rifampicin‑induced Hepatotoxicity in in-vitro Model

   Yibo Tang, Junping Lv, Jing Wang, Bing Li, Qiaohui Zhang, Zhenquan Liu, Xiuhui Ke, Weizao Luo, Yin Lin, Yan Liao

   pp. 637–643 · DOI: 10.4103/pm.pm_542_19 · 2020

   Objectives: In this study, we aimed to investigate the protective effect and the underlying mechanisms of SSP in cultured HepG2 cells after induction with INH and RFP. Materials and Methods: The study was designed as fol…

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10. Article

    Methanolic Extracts of Capparis ecuadorica Iltis Inhibit the Inflammatory Response in Lipopolysaccharide‑Stimulated RAW 264.7 Macrophage Cells

    Bo Ram Song, Ji Eun Kim, Jin Ju Park, Mi Rim Lee, Jun Young Choi, Jin Kyung Noh, Hyun Keun Song, Dae Youn Hwang

    pp. 644–653 · DOI: 10.4103/pm.pm_464_19 · 2020

    Objectives: In this study, we investigated the anti‑inflammatory activity of a methanolic extract of C. ecuadorica leaves (MCE) in macrophages. Materials and Methods: Anti‑inflammatory responses and mechanisms were asses…

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11. Article

    Distinguishing the Rhizomes of Atractylodes japonica, Atractylodes chinensis, and Atractylodes lancea by Comprehensive Two‑Dimensional Gas Chromatography Coupled with Mass Spectrometry Combined with Multivariate Data Analysis

    Jie Lu, WenTing Chen, BoWen Zhou, Yang Chen, XinHong Wang, Rui An, Ming Yang

    pp. 654–661 · DOI: 10.4103/pm.pm_33_20 · 2020

    Background: In clinical practice, the species of Atractylodes are difficult to identify based on their morphological and chemical features which often leads to confusion. In addition, the composition of volatile componen…

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12. Article

    Content Determination and Anti-fatigue Effect of the Purified Anthocyanin from Purple Daucus carota

    Fang-Rong Cheng, Yue-Yue Mao, Song-Heng Jin, Rong-Rong Cai, Ke Yuan

    pp. 670–674 · DOI: 10.4103/pm.pm_452_19 · 2020

    Background: The genus <em>Cissus</em> (Vitaceae) is known for its medicinal properties. <em>Cissus quadrangularis</em> is a well-known medicinal plant used in traditional medicine for bone healing. Objective: The present…

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13. Article

    Glabridin Downregulates Lipopolysaccharide‑Induced Oxidative Stress and Neuroinflammation in BV‑2 Microglial Cells via Suppression of Nuclear Factor‑κB Signaling Pathway

    Yan Wu, Jia Geng, Xiaoguang Lei, Qian Wu, Tao Chen, Lianmei Zhong

    pp. 675–680 · DOI: 10.4103/pm.pm_497_19 · 2020

    Background: Microglia initially undergoes chronic activation in response to the damages caused by stressful stimuli, such as bacterial infection and hypoxia. Inflammatory responses, as well as oxidative stress, perform c…

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14. Article

    Fucoxanthin Modulates the Development of 7, 12-dimethyl benz (a) anthracene-induced Skin Carcinogenesis in Swiss Albino Mice in vivo

    Pengtao Kou, Najat Marraiki, Abdallah M. Elgorban, Yaowu Du

    pp. 681–688 · DOI: 10.4103/pm.pm_292_19 · 2020

    Background: Fucoxanthin (Fx), an distinctive carotenoid occurs on brown seaweed, contains several benefits including anti‑cancer effects. To investigate the chemopreventive effectual of Fx on 7,12‑dimethylbenz[a] anthrac…

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